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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZNF232

Z-value: 0.27

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Transcription factors associated with ZNF232

Gene Symbol Gene ID Gene Info
ZNF232
ENSG00000167840.9 zinc finger protein 232

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF232hg19_v2_chr17_-_5015129_5015187-0.462.2e-02Click!

Activity profile of ZNF232 motif

Sorted Z-values of ZNF232 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_225811747 0.71 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr7_-_56101826 0.31 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr7_+_142919130 0.31 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr10_+_134150835 0.25 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr18_+_61637159 0.20 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr19_-_10491130 0.20 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr3_+_153202284 0.19 ENST00000446603.2
C3orf79
chromosome 3 open reading frame 79
chr2_-_113522177 0.18 ENST00000541405.1
CKAP2L
cytoskeleton associated protein 2-like
chr1_-_204654826 0.17 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr3_-_185216811 0.17 ENST00000421852.1
TMEM41A
transmembrane protein 41A
chr19_-_10491234 0.16 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chrX_+_30261847 0.15 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr1_+_156105878 0.13 ENST00000508500.1
LMNA
lamin A/C
chr2_+_74425689 0.13 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr19_-_11545920 0.13 ENST00000356392.4
ENST00000591179.1
CCDC151
coiled-coil domain containing 151
chr1_-_36107445 0.13 ENST00000373237.3
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr16_+_30662050 0.11 ENST00000568754.1
PRR14
proline rich 14
chr14_+_23016437 0.11 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr1_+_237205476 0.10 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chrY_+_15016013 0.10 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_-_113522248 0.10 ENST00000302450.6
CKAP2L
cytoskeleton associated protein 2-like
chr2_-_74619152 0.09 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr6_+_109416684 0.09 ENST00000521522.1
ENST00000524064.1
ENST00000522608.1
ENST00000521503.1
ENST00000519407.1
ENST00000519095.1
ENST00000368968.2
ENST00000522490.1
ENST00000523209.1
ENST00000368970.2
ENST00000520883.1
ENST00000523787.1
CEP57L1
centrosomal protein 57kDa-like 1
chr7_+_1609694 0.09 ENST00000437621.2
ENST00000457484.2
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr2_-_74618964 0.08 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr15_-_79383102 0.07 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr20_+_4129426 0.07 ENST00000339123.6
ENST00000305958.4
ENST00000278795.3
SMOX
spermine oxidase
chr4_-_84255935 0.07 ENST00000513463.1
HPSE
heparanase
chr2_+_102413726 0.07 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_185216766 0.06 ENST00000296254.3
TMEM41A
transmembrane protein 41A
chr17_-_3301704 0.06 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr16_+_30662360 0.06 ENST00000542965.2
PRR14
proline rich 14
chr14_-_107131560 0.06 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr16_+_30662184 0.06 ENST00000300835.4
PRR14
proline rich 14
chr1_-_153029980 0.05 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr10_+_50817141 0.05 ENST00000339797.1
CHAT
choline O-acetyltransferase
chr19_-_50380536 0.05 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr5_+_31532373 0.05 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr11_-_117800080 0.05 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13
transmembrane protease, serine 13
chr9_+_117085336 0.04 ENST00000259396.8
ENST00000538816.1
ORM1
orosomucoid 1
chr6_+_109416313 0.04 ENST00000521277.1
ENST00000517392.1
ENST00000407272.1
ENST00000336977.4
ENST00000519286.1
ENST00000518329.1
ENST00000522461.1
ENST00000518853.1
CEP57L1
centrosomal protein 57kDa-like 1
chr3_+_8543533 0.04 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr8_-_143999259 0.04 ENST00000323110.2
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr19_-_38210622 0.04 ENST00000591664.1
ENST00000355202.4
ZNF607
zinc finger protein 607
chr10_-_61900762 0.04 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_+_228735763 0.04 ENST00000373666.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr3_+_51863433 0.04 ENST00000444293.1
IQCF3
IQ motif containing F3
chr7_-_83278322 0.03 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr16_-_4852915 0.03 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr17_+_26800648 0.03 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr18_+_55816546 0.03 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr19_+_18043810 0.03 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chr17_+_26800756 0.03 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_-_79472365 0.03 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr4_+_96761238 0.03 ENST00000295266.4
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2
chr14_-_24711806 0.03 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_+_26800296 0.03 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr14_-_24711865 0.02 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr16_-_11367452 0.02 ENST00000327157.2
PRM3
protamine 3
chr1_-_160549235 0.02 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr1_-_16556038 0.02 ENST00000375605.2
C1orf134
chromosome 1 open reading frame 134
chrY_+_15016725 0.02 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrX_-_130423386 0.01 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr1_-_173572181 0.01 ENST00000536496.1
ENST00000367714.3
SLC9C2
solute carrier family 9, member C2 (putative)
chrX_-_100548045 0.01 ENST00000372907.3
ENST00000372905.2
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr3_+_184018352 0.01 ENST00000435761.1
ENST00000439383.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr2_+_241807870 0.01 ENST00000307503.3
AGXT
alanine-glyoxylate aminotransferase
chr9_+_5231413 0.01 ENST00000239316.4
INSL4
insulin-like 4 (placenta)
chr17_-_6915646 0.00 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr15_-_34635314 0.00 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr5_+_177435986 0.00 ENST00000398106.2
FAM153C
family with sequence similarity 153, member C
chr1_-_193074504 0.00 ENST00000367439.3
GLRX2
glutaredoxin 2
chrX_+_100805496 0.00 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr10_-_27389392 0.00 ENST00000376087.4
ANKRD26
ankyrin repeat domain 26
chr2_-_31637560 0.00 ENST00000379416.3
XDH
xanthine dehydrogenase

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0052895 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)