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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZNF263

Z-value: 0.59

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Transcription factors associated with ZNF263

Gene Symbol Gene ID Gene Info
ZNF263
ENSG00000006194.6 zinc finger protein 263

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF263hg19_v2_chr16_+_3313791_33138340.077.3e-01Click!

Activity profile of ZNF263 motif

Sorted Z-values of ZNF263 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_29595779 2.41 ENST00000355973.3
ENST00000377012.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_+_77020224 2.14 ENST00000339142.2
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr16_+_86544113 1.96 ENST00000262426.4
FOXF1
forkhead box F1
chr6_-_32821599 1.93 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_+_74702214 1.83 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr17_+_77020325 1.83 ENST00000311661.4
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr6_+_32821924 1.75 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_-_127542021 1.65 ENST00000434178.2
MGLL
monoglyceride lipase
chr19_-_55658687 1.64 ENST00000593046.1
TNNT1
troponin T type 1 (skeletal, slow)
chr3_-_127542051 1.62 ENST00000398104.1
MGLL
monoglyceride lipase
chr16_-_75590114 1.13 ENST00000568377.1
ENST00000565067.1
ENST00000258173.6
TMEM231
transmembrane protein 231
chr3_-_127541679 1.06 ENST00000265052.5
MGLL
monoglyceride lipase
chr17_+_77020146 1.01 ENST00000579760.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_+_44037546 0.99 ENST00000601282.1
ZNF575
zinc finger protein 575
chr7_-_47621736 0.95 ENST00000311160.9
TNS3
tensin 3
chr12_+_52626898 0.94 ENST00000331817.5
KRT7
keratin 7
chr19_-_55658281 0.93 ENST00000585321.2
ENST00000587465.2
TNNT1
troponin T type 1 (skeletal, slow)
chr6_-_30654977 0.93 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr4_-_74864386 0.92 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr13_-_44361025 0.87 ENST00000261488.6
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr1_-_205782304 0.83 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr16_+_57662138 0.80 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56
G protein-coupled receptor 56
chr16_+_57662419 0.79 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr5_+_129240151 0.73 ENST00000305031.4
CHSY3
chondroitin sulfate synthase 3
chr7_-_77045617 0.69 ENST00000257626.7
GSAP
gamma-secretase activating protein
chr9_+_109625378 0.67 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr11_-_46142948 0.64 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr6_+_71998506 0.64 ENST00000370435.4
OGFRL1
opioid growth factor receptor-like 1
chr8_+_56014949 0.63 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr1_+_90286562 0.63 ENST00000525774.1
ENST00000337338.5
LRRC8D
leucine rich repeat containing 8 family, member D
chr1_-_120612240 0.62 ENST00000256646.2
NOTCH2
notch 2
chr17_+_73750699 0.61 ENST00000584939.1
ITGB4
integrin, beta 4
chr19_-_47975417 0.60 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_-_51893827 0.59 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr14_+_55033815 0.58 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr8_+_31497271 0.57 ENST00000520407.1
NRG1
neuregulin 1
chr19_-_44174330 0.57 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr3_+_105086056 0.56 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr10_-_49701686 0.55 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr19_-_10679697 0.55 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr19_-_10679644 0.55 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr11_-_72492903 0.55 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr3_+_105085734 0.54 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr4_-_38666430 0.54 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr17_+_46985731 0.53 ENST00000360943.5
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr19_-_44306590 0.53 ENST00000377950.3
LYPD5
LY6/PLAUR domain containing 5
chr14_-_27066960 0.52 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr5_-_146833222 0.52 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr1_+_171107241 0.51 ENST00000236166.3
FMO6P
flavin containing monooxygenase 6 pseudogene
chr1_-_89664595 0.51 ENST00000355754.6
GBP4
guanylate binding protein 4
chr5_-_146833485 0.51 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr19_-_44174305 0.50 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr1_+_209848749 0.50 ENST00000367029.4
G0S2
G0/G1switch 2
chr1_+_167599330 0.49 ENST00000367854.3
ENST00000361496.3
RCSD1
RCSD domain containing 1
chr17_-_20370847 0.49 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr11_-_72492878 0.49 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_+_18155560 0.48 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chr7_+_55086703 0.48 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr11_-_57089671 0.48 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_-_4414880 0.47 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr2_-_231989808 0.46 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr2_-_11810284 0.46 ENST00000306928.5
NTSR2
neurotensin receptor 2
chr11_-_46142615 0.46 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr8_+_90769967 0.45 ENST00000220751.4
RIPK2
receptor-interacting serine-threonine kinase 2
chr5_-_121413974 0.44 ENST00000231004.4
LOX
lysyl oxidase
chr6_+_18155632 0.44 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr2_-_27718052 0.44 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr15_-_64338521 0.44 ENST00000457488.1
ENST00000558069.1
DAPK2
death-associated protein kinase 2
chr3_+_184098065 0.44 ENST00000348986.3
CHRD
chordin
chr4_-_113207048 0.43 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr14_+_93799556 0.42 ENST00000256339.4
UNC79
unc-79 homolog (C. elegans)
chr12_+_54943134 0.42 ENST00000243052.3
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr1_+_28199047 0.41 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
THEMIS2
thymocyte selection associated family member 2
chr1_+_166808692 0.41 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr22_+_41697520 0.40 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr3_+_133292759 0.40 ENST00000431519.2
CDV3
CDV3 homolog (mouse)
chr6_+_4776580 0.40 ENST00000397588.3
CDYL
chromodomain protein, Y-like
chr10_+_73724123 0.40 ENST00000373115.4
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr14_-_65409438 0.40 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_65409502 0.40 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_-_51975942 0.39 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr11_-_46142505 0.39 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr17_+_21191341 0.39 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr3_+_133292851 0.39 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr6_+_83073952 0.38 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr19_+_36249044 0.38 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
C19orf55
chromosome 19 open reading frame 55
chr2_-_60780536 0.38 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr5_+_135385202 0.38 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr6_-_31324943 0.38 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr17_+_25958174 0.38 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr3_+_184097905 0.37 ENST00000450923.1
CHRD
chordin
chr15_-_40212363 0.37 ENST00000299092.3
GPR176
G protein-coupled receptor 176
chr8_-_119124045 0.37 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr8_+_31496809 0.37 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr17_-_45928521 0.37 ENST00000536300.1
SP6
Sp6 transcription factor
chr11_-_64646086 0.37 ENST00000320631.3
EHD1
EH-domain containing 1
chr19_+_12902289 0.37 ENST00000302754.4
JUNB
jun B proto-oncogene
chr11_-_117698765 0.36 ENST00000532119.1
FXYD2
FXYD domain containing ion transport regulator 2
chr7_-_96654133 0.36 ENST00000486603.2
ENST00000222598.4
DLX5
distal-less homeobox 5
chr11_+_33061543 0.36 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr6_+_126112001 0.36 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr3_+_184097836 0.35 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr21_-_16437255 0.35 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr16_+_23690138 0.35 ENST00000300093.4
PLK1
polo-like kinase 1
chr16_+_30671223 0.35 ENST00000568722.1
FBRS
fibrosin
chr9_-_21975038 0.34 ENST00000446177.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr21_-_16437126 0.34 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr12_+_6930813 0.34 ENST00000428545.2
GPR162
G protein-coupled receptor 162
chr3_+_11196206 0.34 ENST00000431010.2
HRH1
histamine receptor H1
chr11_+_33060963 0.34 ENST00000530419.1
ENST00000334274.4
TCP11L1
t-complex 11, testis-specific-like 1
chr8_+_22462532 0.34 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr4_-_80994471 0.33 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr17_-_1083078 0.33 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr12_+_6930703 0.33 ENST00000311268.3
GPR162
G protein-coupled receptor 162
chr14_+_55034330 0.33 ENST00000251091.5
SAMD4A
sterile alpha motif domain containing 4A
chr8_-_26371608 0.33 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr12_+_4382917 0.33 ENST00000261254.3
CCND2
cyclin D2
chr14_+_33408449 0.33 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3
neuronal PAS domain protein 3
chr10_-_25305011 0.33 ENST00000331161.4
ENST00000376363.1
ENKUR
enkurin, TRPC channel interacting protein
chr1_+_155107820 0.33 ENST00000484157.1
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr22_+_31644388 0.33 ENST00000333611.4
ENST00000340552.4
LIMK2
LIM domain kinase 2
chr9_-_21974820 0.32 ENST00000579122.1
ENST00000498124.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr12_-_54779511 0.32 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr2_-_231084820 0.32 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr4_-_5891918 0.32 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr11_+_74951948 0.32 ENST00000562197.2
TPBGL
trophoblast glycoprotein-like
chr14_-_24020858 0.32 ENST00000419474.3
ZFHX2
zinc finger homeobox 2
chrX_-_74145273 0.31 ENST00000055682.6
KIAA2022
KIAA2022
chr1_-_156722015 0.31 ENST00000368209.5
HDGF
hepatoma-derived growth factor
chr6_-_169654139 0.31 ENST00000366787.3
THBS2
thrombospondin 2
chr1_-_201096312 0.31 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr20_+_45523227 0.31 ENST00000327619.5
ENST00000357410.3
EYA2
eyes absent homolog 2 (Drosophila)
chr9_+_33629119 0.31 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr12_+_6930964 0.31 ENST00000382315.3
GPR162
G protein-coupled receptor 162
chr7_+_100728720 0.31 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr2_-_225450013 0.31 ENST00000264414.4
CUL3
cullin 3
chr1_+_212782012 0.30 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr3_+_133292574 0.30 ENST00000264993.3
CDV3
CDV3 homolog (mouse)
chr1_-_156721389 0.30 ENST00000537739.1
HDGF
hepatoma-derived growth factor
chr17_-_53499310 0.30 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr6_+_69345166 0.29 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr9_-_130477912 0.29 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr3_-_42744312 0.29 ENST00000416756.1
ENST00000441594.1
HHATL
hedgehog acyltransferase-like
chr10_-_79397391 0.28 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_+_56111361 0.27 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr15_+_92937144 0.27 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr3_-_46735155 0.27 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr22_-_42017021 0.27 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr14_-_51297837 0.27 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr7_+_28725585 0.27 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr7_-_100493744 0.27 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr7_+_134331550 0.27 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM
2,3-bisphosphoglycerate mutase
chr11_-_128392085 0.27 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr5_-_95297534 0.27 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chrX_-_68385274 0.27 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr9_+_35673853 0.27 ENST00000378357.4
CA9
carbonic anhydrase IX
chr4_-_153457197 0.27 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr6_-_114664180 0.27 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr6_+_7541845 0.27 ENST00000418664.2
DSP
desmoplakin
chr1_+_46269248 0.26 ENST00000361297.2
ENST00000372009.2
MAST2
microtubule associated serine/threonine kinase 2
chr19_+_59055814 0.26 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28
tripartite motif containing 28
chrX_-_68385354 0.26 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr3_+_190231891 0.26 ENST00000434491.1
ENST00000422940.1
ENST00000317757.3
IL1RAP
interleukin 1 receptor accessory protein
chr1_-_111743285 0.26 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr10_+_23983671 0.26 ENST00000376462.1
KIAA1217
KIAA1217
chr5_+_156693091 0.26 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr14_-_24740709 0.26 ENST00000399409.3
ENST00000216840.6
RABGGTA
Rab geranylgeranyltransferase, alpha subunit
chr4_-_80994619 0.26 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr22_+_18593446 0.26 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr4_-_80993717 0.26 ENST00000307333.7
ANTXR2
anthrax toxin receptor 2
chr2_+_154728426 0.26 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr15_-_71146480 0.26 ENST00000299213.8
LARP6
La ribonucleoprotein domain family, member 6
chr1_-_6321035 0.26 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr1_+_205473720 0.25 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr2_-_224702257 0.25 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr4_+_140222609 0.25 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr8_+_81397876 0.25 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr2_-_64881018 0.25 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr14_-_27066636 0.25 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr11_+_71640112 0.25 ENST00000530137.1
RNF121
ring finger protein 121
chr11_+_73676281 0.25 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr19_+_57106647 0.25 ENST00000328070.6
ZNF71
zinc finger protein 71
chrX_+_153409678 0.25 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr3_+_38323785 0.25 ENST00000466887.1
ENST00000448498.1
SLC22A14
solute carrier family 22, member 14
chr2_-_231084617 0.25 ENST00000409815.2
SP110
SP110 nuclear body protein
chr1_+_147374915 0.25 ENST00000240986.4
GJA8
gap junction protein, alpha 8, 50kDa
chr18_-_51750948 0.25 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr18_-_47721447 0.24 ENST00000285039.7
MYO5B
myosin VB
chr12_-_53625958 0.24 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr10_+_71561704 0.24 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr2_-_50574856 0.24 ENST00000342183.5
NRXN1
neurexin 1
chr1_-_2461684 0.24 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr7_-_92463210 0.24 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr20_-_62203808 0.24 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr10_+_89419370 0.24 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr8_+_22462145 0.24 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr12_-_54785074 0.24 ENST00000338010.5
ENST00000550774.1
ZNF385A
zinc finger protein 385A
chr8_+_32405728 0.24 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1
neuregulin 1
chr8_+_32405785 0.24 ENST00000287842.3
NRG1
neuregulin 1
chrX_-_130423386 0.24 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) right lung development(GO:0060458)
0.6 5.0 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.6 4.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.5 1.9 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 1.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.3 2.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 1.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.7 GO:1904800 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 0.4 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 0.8 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.5 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.1 0.4 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.5 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 3.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.3 GO:1901656 glycoside transport(GO:1901656)
0.1 0.3 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.9 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 0.1 GO:0060516 primary prostatic bud elongation(GO:0060516)
0.1 1.0 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.1 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.3 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.3 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.1 0.2 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.3 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.3 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.2 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.2 GO:1904172 NAD transport(GO:0043132) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.2 GO:1903762 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.2 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 2.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.4 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.2 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.6 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.5 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0003193 pulmonary valve formation(GO:0003193) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:2001168 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.1 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.1 GO:1902869 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.0 0.0 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:1904627 negative regulation of monocyte differentiation(GO:0045656) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0070213 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.2 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 2.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.3 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0035524 leucine transport(GO:0015820) proline transmembrane transport(GO:0035524)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.0 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.2 GO:0061635 negative regulation of growth of symbiont in host(GO:0044130) regulation of protein complex stability(GO:0061635)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.9 GO:0042825 TAP complex(GO:0042825)
0.2 1.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.6 GO:0044609 DBIRD complex(GO:0044609)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 2.6 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 4.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 4.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 1.9 GO:0046979 TAP2 binding(GO:0046979)
0.2 4.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.7 GO:0031014 troponin T binding(GO:0031014)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 2.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 1.1 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.4 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.3 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.5 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 3.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.1 GO:0043739 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.2 PID P73PATHWAY p73 transcription factor network
0.0 3.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation