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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZNF282

Z-value: 0.53

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_1488925800.193.5e-01Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_93964158 1.68 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chrX_-_135849484 1.06 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_+_101967257 0.99 ENST00000543253.1
ENST00000535209.1
GPRASP2
G protein-coupled receptor associated sorting protein 2
chr12_-_46766577 0.98 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr13_+_50656307 0.78 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr17_+_66509019 0.78 ENST00000585981.1
ENST00000589480.1
ENST00000585815.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr11_-_66445219 0.77 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RBM4B
RNA binding motif protein 4B
chr7_+_139026057 0.73 ENST00000541515.3
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr22_+_27017921 0.69 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr7_+_139025875 0.69 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr5_+_175299743 0.63 ENST00000502265.1
CPLX2
complexin 2
chr6_-_36807762 0.63 ENST00000244751.2
CPNE5
copine V
chr8_-_27630102 0.62 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
CCDC25
coiled-coil domain containing 25
chr16_+_67204400 0.60 ENST00000563439.1
ENST00000432069.2
ENST00000564992.1
ENST00000564053.1
NOL3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr14_-_36989336 0.59 ENST00000522719.2
NKX2-1
NK2 homeobox 1
chr16_+_66586461 0.59 ENST00000264001.4
ENST00000351137.4
ENST00000345436.4
ENST00000362093.4
ENST00000417030.2
ENST00000527729.1
ENST00000532838.1
CKLF
CKLF-CMTM1
chemokine-like factor
CKLF-CMTM1 readthrough
chr2_-_188378368 0.54 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr9_+_34652164 0.54 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr8_+_10383039 0.52 ENST00000328655.3
ENST00000522210.1
PRSS55
protease, serine, 55
chr6_-_79944336 0.50 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr13_-_103019744 0.48 ENST00000437115.2
FGF14-IT1
FGF14 intronic transcript 1 (non-protein coding)
chr1_+_2004901 0.45 ENST00000400921.2
PRKCZ
protein kinase C, zeta
chr16_+_29802036 0.45 ENST00000561482.1
ENST00000160827.4
ENST00000569636.2
ENST00000400750.2
KIF22
kinesin family member 22
chr3_-_180707306 0.43 ENST00000479269.1
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr4_+_52709229 0.43 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chr17_-_76899275 0.43 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr15_+_38276910 0.42 ENST00000558081.2
RP11-1008C21.1
RP11-1008C21.1
chr4_+_88343952 0.42 ENST00000440591.2
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr4_+_88343717 0.40 ENST00000302174.4
ENST00000512216.1
ENST00000473942.1
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr11_+_63998006 0.38 ENST00000355040.4
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr1_-_54303934 0.37 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr1_-_54303949 0.37 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr1_+_52682052 0.36 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr1_+_2005425 0.35 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr1_+_17248418 0.35 ENST00000375541.5
CROCC
ciliary rootlet coiled-coil, rootletin
chr12_-_127256772 0.35 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr1_+_160313062 0.33 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
NCSTN
nicastrin
chr19_-_39390440 0.33 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr3_-_180707466 0.33 ENST00000491873.1
ENST00000486355.1
ENST00000382564.2
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr1_-_24151892 0.32 ENST00000235958.4
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr11_-_321340 0.31 ENST00000526811.1
IFITM3
interferon induced transmembrane protein 3
chr1_-_24151903 0.31 ENST00000436439.2
ENST00000374490.3
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_+_145507587 0.30 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr17_-_56605341 0.30 ENST00000583114.1
SEPT4
septin 4
chr4_-_74904398 0.29 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr12_-_9102549 0.28 ENST00000000412.3
M6PR
mannose-6-phosphate receptor (cation dependent)
chr5_+_140552218 0.25 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr19_+_44617511 0.24 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr2_+_242289502 0.24 ENST00000451310.1
SEPT2
septin 2
chr7_-_158497431 0.24 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
NCAPG2
non-SMC condensin II complex, subunit G2
chr11_+_111957497 0.23 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr18_+_54318566 0.23 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr2_-_241497374 0.23 ENST00000373318.2
ENST00000406958.1
ENST00000391987.1
ENST00000373320.4
ANKMY1
ankyrin repeat and MYND domain containing 1
chr1_+_45792541 0.22 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr21_+_35747773 0.21 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
SMIM11
small integral membrane protein 11
chr15_+_51200871 0.21 ENST00000560508.1
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr1_-_160313025 0.21 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr19_-_39390350 0.21 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr11_+_66278080 0.20 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
BBS1
Bardet-Biedl syndrome 1
chr16_+_67927147 0.20 ENST00000291041.5
PSKH1
protein serine kinase H1
chr3_+_45927994 0.20 ENST00000357632.2
ENST00000395963.2
CCR9
chemokine (C-C motif) receptor 9
chr6_-_32152020 0.20 ENST00000375055.2
AGER
advanced glycosylation end product-specific receptor
chr19_-_51340469 0.19 ENST00000326856.4
KLK15
kallikrein-related peptidase 15
chr2_-_241497390 0.19 ENST00000272972.3
ENST00000401804.1
ENST00000361678.4
ENST00000405523.3
ANKMY1
ankyrin repeat and MYND domain containing 1
chr21_-_35014027 0.19 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr15_+_51200859 0.18 ENST00000261842.5
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr6_-_32152064 0.18 ENST00000375076.4
ENST00000375070.3
AGER
advanced glycosylation end product-specific receptor
chr6_+_32938692 0.18 ENST00000443797.2
BRD2
bromodomain containing 2
chr15_-_44955842 0.18 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
SPG11
spastic paraplegia 11 (autosomal recessive)
chr1_+_35247859 0.18 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr17_-_73937116 0.16 ENST00000586717.1
ENST00000389570.4
ENST00000319129.5
FBF1
Fas (TNFRSF6) binding factor 1
chr19_-_6110474 0.16 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr6_-_17706618 0.15 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr6_+_32938665 0.14 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr6_+_44187334 0.14 ENST00000313248.7
ENST00000427851.2
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr4_+_39460689 0.13 ENST00000381846.1
LIAS
lipoic acid synthetase
chr6_+_39760783 0.13 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr6_-_32151999 0.13 ENST00000375069.3
ENST00000538695.1
ENST00000438221.2
ENST00000375065.5
ENST00000450110.1
ENST00000375067.3
ENST00000375056.2
AGER
advanced glycosylation end product-specific receptor
chr17_+_41323204 0.13 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1
neighbor of BRCA1 gene 1
chrX_-_49121165 0.12 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr3_-_49907323 0.12 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr1_-_54304212 0.11 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr20_-_43150601 0.11 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr18_-_47017956 0.10 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr2_-_197664366 0.10 ENST00000409364.3
ENST00000263956.3
GTF3C3
general transcription factor IIIC, polypeptide 3, 102kDa
chr11_-_111957451 0.10 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr1_+_226250379 0.10 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr2_+_232260254 0.09 ENST00000287590.5
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr16_-_70239683 0.08 ENST00000601706.1
AC009060.1
Uncharacterized protein
chr13_+_31309645 0.07 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr17_+_55183261 0.07 ENST00000576295.1
AKAP1
A kinase (PRKA) anchor protein 1
chr1_-_2126192 0.07 ENST00000378546.4
C1orf86
chromosome 1 open reading frame 86
chr4_+_39460659 0.07 ENST00000513731.1
LIAS
lipoic acid synthetase
chr2_+_233897382 0.05 ENST00000233840.3
NEU2
sialidase 2 (cytosolic sialidase)
chr4_+_39460620 0.05 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr9_+_139221880 0.05 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr10_+_114206956 0.05 ENST00000432306.1
ENST00000393077.2
VTI1A
vesicle transport through interaction with t-SNAREs 1A
chr19_-_49121054 0.04 ENST00000546623.1
ENST00000084795.5
RPL18
ribosomal protein L18
chr17_-_79905109 0.04 ENST00000409745.2
MYADML2
myeloid-associated differentiation marker-like 2
chr12_-_13248562 0.04 ENST00000457134.2
ENST00000537302.1
GSG1
germ cell associated 1
chr5_+_150816595 0.04 ENST00000520111.1
ENST00000520701.1
ENST00000429484.2
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr22_-_24641027 0.04 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5
gamma-glutamyltransferase 5
chr5_+_78365577 0.04 ENST00000518666.1
ENST00000521567.1
BHMT2
betaine--homocysteine S-methyltransferase 2
chr17_-_61959202 0.04 ENST00000449787.2
ENST00000456543.2
ENST00000423893.2
ENST00000332800.7
GH2
growth hormone 2
chr18_-_47018869 0.03 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr8_-_21988558 0.03 ENST00000312841.8
HR
hair growth associated
chr5_+_65892174 0.03 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_-_72095622 0.03 ENST00000290273.5
DMRTC1
DMRT-like family C1
chr6_+_129204337 0.03 ENST00000421865.2
LAMA2
laminin, alpha 2
chr18_-_47018897 0.03 ENST00000418495.1
RPL17
ribosomal protein L17
chr7_-_155326532 0.02 ENST00000406197.1
ENST00000321736.5
CNPY1
canopy FGF signaling regulator 1
chr6_+_10748019 0.02 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chrX_+_47004639 0.02 ENST00000345781.6
RBM10
RNA binding motif protein 10
chr14_-_36989427 0.01 ENST00000354822.5
NKX2-1
NK2 homeobox 1
chr18_-_54318353 0.01 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr6_+_106959718 0.01 ENST00000369066.3
AIM1
absent in melanoma 1
chr10_-_126480381 0.00 ENST00000368836.2
METTL10
methyltransferase like 10
chrX_-_13835461 0.00 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.3 0.8 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.2 0.6 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 0.5 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 0.5 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.8 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.0 GO:0032328 alanine transport(GO:0032328)
0.1 0.3 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.3 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 1.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.8 GO:0048806 genitalia development(GO:0048806)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.3 GO:0034205 beta-amyloid formation(GO:0034205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.6 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.8 GO:0043203 axon hillock(GO:0043203) apical cortex(GO:0045179)
0.1 0.2 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 0.5 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.2 0.8 GO:0043262 ADP-sugar diphosphatase activity(GO:0019144) adenosine-diphosphatase activity(GO:0043262)
0.1 0.6 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.3 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.6 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)