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Inflammatory response time course, HUVEC (Wada et al., 2009)

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Results for ZNF350

Z-value: 0.37

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_52490113-0.048.7e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_77155856 0.76 ENST00000253506.5
ENST00000591814.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_68165657 0.63 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_99578776 0.62 ENST00000515287.1
tetraspanin 5
chr15_-_57210769 0.57 ENST00000559000.1
zinc finger protein 280D
chr16_-_46864955 0.56 ENST00000565112.1
chromosome 16 open reading frame 87
chr18_+_77155942 0.55 ENST00000397790.2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_+_132286754 0.53 ENST00000434330.1
coiled-coil domain containing 74A
chr19_+_39903185 0.48 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr4_-_99578789 0.42 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr11_-_45687128 0.40 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr19_+_39904168 0.39 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_98510843 0.38 ENST00000413670.2
ENST00000538428.1
MIR137 host gene (non-protein coding)
chr2_-_157198860 0.32 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr17_-_39968855 0.30 ENST00000355468.3
ENST00000590496.1
leprecan-like 4
chr16_-_46865286 0.30 ENST00000285697.4
chromosome 16 open reading frame 87
chr15_+_57210818 0.28 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr2_+_132287237 0.28 ENST00000467992.2
coiled-coil domain containing 74A
chr10_+_50822480 0.27 ENST00000455728.2
choline O-acetyltransferase
chr4_+_108910870 0.26 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chr11_-_63381925 0.25 ENST00000415826.1
phospholipase A2, group XVI
chr4_+_108911036 0.21 ENST00000505878.1
hydroxyacyl-CoA dehydrogenase
chr5_+_42423872 0.21 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr17_-_39674668 0.21 ENST00000393981.3
keratin 15
chr3_-_128212016 0.21 ENST00000498200.1
ENST00000341105.2
GATA binding protein 2
chr20_-_35374456 0.20 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG family member 3
chr20_+_62367989 0.18 ENST00000309546.3
Lck interacting transmembrane adaptor 1
chr1_-_33647267 0.18 ENST00000291416.5
tripartite motif containing 62
chr9_+_12693336 0.18 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr1_+_12123414 0.17 ENST00000263932.2
tumor necrosis factor receptor superfamily, member 8
chr5_-_107717058 0.17 ENST00000359660.5
F-box and leucine-rich repeat protein 17
chr15_+_57210961 0.16 ENST00000557843.1
transcription factor 12
chr12_-_109219937 0.15 ENST00000546697.1
slingshot protein phosphatase 1
chr11_+_7041677 0.14 ENST00000299481.4
NLR family, pyrin domain containing 14
chr1_-_155948218 0.14 ENST00000313667.4
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_-_119217365 0.14 ENST00000360167.4
ENST00000555262.1
ENST00000449574.2
ENST00000445041.2
membrane frizzled-related protein
C1q and tumor necrosis factor related protein 5
chr11_-_63381823 0.13 ENST00000323646.5
phospholipase A2, group XVI
chr16_-_46865047 0.13 ENST00000394806.2
chromosome 16 open reading frame 87
chr19_+_42829702 0.13 ENST00000334370.4
multiple EGF-like-domains 8
chr4_+_120133791 0.13 ENST00000274030.6
ubiquitin specific peptidase 53
chrX_-_134232630 0.13 ENST00000535837.1
ENST00000433425.2
long intergenic non-protein coding RNA 87
chr4_-_174255400 0.13 ENST00000506267.1
high mobility group box 2
chr17_+_48624450 0.13 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
spermatogenesis associated 20
chr17_+_19030782 0.13 ENST00000344415.4
ENST00000577213.1
GRB2-related adaptor protein-like
chr20_+_4667094 0.13 ENST00000424424.1
ENST00000457586.1
prion protein
chr20_+_4666882 0.12 ENST00000379440.4
ENST00000430350.2
prion protein
chr11_-_68671244 0.11 ENST00000567045.1
ENST00000450904.2
mitochondrial ribosomal protein L21
chr11_-_68671264 0.11 ENST00000362034.2
mitochondrial ribosomal protein L21
chrX_+_120181457 0.11 ENST00000328078.1
glutamate dehydrogenase 2
chr1_+_29213678 0.11 ENST00000347529.3
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_51425902 0.10 ENST00000396153.2
Fas (TNFRSF6) associated factor 1
chr10_+_69644404 0.10 ENST00000212015.6
sirtuin 1
chr19_+_5681011 0.10 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr7_+_2559399 0.10 ENST00000222725.5
ENST00000359574.3
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_-_46089718 0.10 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
coiled-coil domain containing 17
chr17_-_62340581 0.09 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr11_+_65779283 0.09 ENST00000312134.2
cystatin E/M
chr2_-_70780572 0.09 ENST00000450929.1
transforming growth factor, alpha
chr11_-_327537 0.09 ENST00000602735.1
interferon induced transmembrane protein 3
chr11_-_62473776 0.09 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr8_-_100905363 0.09 ENST00000524245.1
cytochrome c oxidase subunit VIc
chrX_-_120090454 0.09 ENST00000434883.2
cancer/testis antigen family 47, member A7
chr16_+_69600209 0.08 ENST00000566899.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_-_62473706 0.08 ENST00000403550.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_79881408 0.08 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr2_+_238600788 0.08 ENST00000289175.6
ENST00000244815.5
leucine rich repeat (in FLII) interacting protein 1
chr19_+_35532612 0.08 ENST00000600390.1
ENST00000597419.1
hepsin
chr3_+_100328433 0.08 ENST00000273352.3
G protein-coupled receptor 128
chr12_+_50451331 0.07 ENST00000228468.4
acid-sensing (proton-gated) ion channel 1
chr8_-_144679296 0.07 ENST00000317198.6
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_+_4526341 0.07 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
heme oxygenase (decycling) 2
chr16_+_71879861 0.06 ENST00000427980.2
ENST00000568581.1
ataxin 1-like
increased sodium tolerance 1 homolog (yeast)
chr17_+_75283973 0.06 ENST00000431235.2
ENST00000449803.2
septin 9
chr19_+_57050317 0.06 ENST00000301318.3
ENST00000591844.1
ZFP28 zinc finger protein
chr17_-_39597173 0.06 ENST00000246646.3
keratin 38
chr17_+_39969183 0.06 ENST00000321562.4
FK506 binding protein 10, 65 kDa
chr1_-_46089639 0.06 ENST00000445048.2
coiled-coil domain containing 17
chr12_+_50451462 0.06 ENST00000447966.2
acid-sensing (proton-gated) ion channel 1
chr15_+_42694573 0.06 ENST00000397200.4
ENST00000569827.1
calpain 3, (p94)
chr9_-_99616642 0.06 ENST00000478850.1
ENST00000481138.1
zinc finger protein 782
chr11_+_68671310 0.06 ENST00000255078.3
ENST00000539224.1
immunoglobulin mu binding protein 2
chr3_+_50229037 0.06 ENST00000232461.3
ENST00000433068.1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr3_-_151176497 0.06 ENST00000282466.3
immunoglobulin superfamily, member 10
chr4_+_75858290 0.05 ENST00000513238.1
prostate androgen-regulated mucin-like protein 1
chr11_-_414948 0.05 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr4_+_75858318 0.05 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr6_+_36973406 0.04 ENST00000274963.8
FYVE, RhoGEF and PH domain containing 2
chr6_-_28303901 0.04 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
zinc finger and SCAN domain containing 31
chr19_-_17488143 0.04 ENST00000599426.1
ENST00000252590.4
plasmalemma vesicle associated protein
chr2_-_70780770 0.04 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
transforming growth factor, alpha
chr17_-_18950950 0.04 ENST00000284154.5
GRB2-related adaptor protein
chr19_+_2977444 0.04 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr4_+_80748619 0.04 ENST00000504263.1
prostate cancer associated transcript 4 (non-protein coding)
chr2_+_120517174 0.04 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr4_+_80748640 0.03 ENST00000514836.1
prostate cancer associated transcript 4 (non-protein coding)
chr1_-_200379104 0.03 ENST00000367352.3
zinc finger protein 281
chr1_-_200379129 0.03 ENST00000367353.1
zinc finger protein 281
chr2_+_120301997 0.03 ENST00000602047.1
Primary ciliary dyskinesia protein 1
chr17_-_6554877 0.03 ENST00000225728.3
ENST00000575197.1
mediator complex subunit 31
chr1_+_22970119 0.03 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
complement component 1, q subcomponent, C chain
chr16_+_69600058 0.03 ENST00000393742.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_235860616 0.03 ENST00000392011.2
SH3-domain binding protein 4
chr17_+_68071389 0.03 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_-_174255536 0.03 ENST00000446922.2
high mobility group box 2
chr17_+_7487146 0.03 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr11_-_69633792 0.03 ENST00000334134.2
fibroblast growth factor 3
chr17_+_68071458 0.03 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_156611960 0.03 ENST00000361588.5
brevican
chr2_+_120302041 0.02 ENST00000442513.3
ENST00000413369.3
Primary ciliary dyskinesia protein 1
chr12_+_81471816 0.02 ENST00000261206.3
acyl-CoA synthetase short-chain family member 3
chr22_+_22697537 0.02 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr17_-_8093471 0.02 ENST00000389017.4
chromosome 17 open reading frame 59
chr22_+_22020273 0.01 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
peptidylprolyl isomerase (cyclophilin)-like 2
chr2_-_241759622 0.01 ENST00000320389.7
ENST00000498729.2
kinesin family member 1A
chr1_-_204654481 0.01 ENST00000367176.3
leucine rich repeat neuronal 2
chr4_-_174256276 0.01 ENST00000296503.5
high mobility group box 2
chr11_-_64511575 0.01 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_18950310 0.01 ENST00000573099.1
GRB2-related adaptor protein
chr16_+_31225337 0.01 ENST00000322122.3
tripartite motif containing 72
chr16_+_14802801 0.00 ENST00000526520.1
ENST00000531598.2
nuclear pore complex interacting protein family, member A3
chr13_+_50202435 0.00 ENST00000282026.1
ADP-ribosylation factor-like 11
chr3_-_128902729 0.00 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CCHC-type zinc finger, nucleic acid binding protein
chr3_-_128902759 0.00 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
CCHC-type zinc finger, nucleic acid binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.2 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.2 GO:1990535 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.1 0.2 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 1.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 1.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 0.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis