Motif ID: AACCUGG

Z-value: 0.230


Mature miRNA associated with seed AACCUGG:

NamemiRBase Accession
hsa-miR-490-3p MIMAT0002806



Activity profile for motif AACCUGG.

activity profile for motif AACCUGG


Sorted Z-values histogram for motif AACCUGG

Sorted Z-values for motif AACCUGG



Network of associatons between targets according to the STRING database.



First level regulatory network of AACCUGG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_69357019 0.324 NM_001874
CPM
carboxypeptidase M
chr12_-_69326946 0.308 NM_001005502
NM_198320
CPM

carboxypeptidase M

chr1_-_230513390 0.201 NM_024554
PGBD5
piggyBac transposable element derived 5
chr7_+_100797685 0.180 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr7_+_77167351 0.157 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr7_+_77166750 0.154 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_-_8190535 0.154 NM_001135109
NM_001206671
NM_001206672
NM_024557
RIC3



resistance to inhibitors of cholinesterase 3 homolog (C. elegans)



chr1_+_153388999 0.128 NM_176823
S100A7A
S100 calcium binding protein A7A
chr6_-_88411984 0.107 NM_018064
AKIRIN2
akirin 2
chr8_-_93111915 0.098 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_110038992 0.094 NM_145234
CHRDL1
chordin-like 1
chr7_-_139477437 0.088 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr15_-_26874236 0.087 NM_001191321
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr8_-_93029864 0.084 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_110039285 0.083 NM_001143981
NM_001143982
NM_001143983
CHRDL1


chordin-like 1


chr22_+_36649116 0.083 NM_001136540
NM_001136541
NM_003661
NM_145343
APOL1



apolipoprotein L, 1



chr21_+_37536838 0.077 NM_005128
DOPEY2
dopey family member 2
chr20_-_56286540 0.071 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_93107881 0.069 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr15_-_26961911 0.069 NM_001191320
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_+_210444364 0.066 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr20_-_56284945 0.065 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_93115453 0.065 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr19_+_11200037 0.064 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr12_+_54674478 0.064 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chrX_+_152110214 0.063 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr8_-_93107442 0.062 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chrX_+_152082985 0.061 NM_001178106
NM_001178107
NM_001178108
NM_001178109
NM_001178110
NM_007150
ZNF185





zinc finger protein 185 (LIM domain)





chr2_+_171571800 0.061 NM_001003845
SP5
Sp5 transcription factor
chr1_-_8086392 0.061 NM_018948
ERRFI1
ERBB receptor feedback inhibitor 1
chr8_-_93075190 0.060 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_123094377 0.060 NM_001042749
STAG2
stromal antigen 2
chr2_+_210288668 0.057 NM_001039538
MAP2
microtubule-associated protein 2
chr3_-_189840225 0.057 NM_001134418
LEPREL1
leprecan-like 1
chr5_+_109025135 0.057 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chrX_+_152086408 0.057 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr20_-_56285576 0.056 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr11_+_125462736 0.056 NM_152713
STT3A
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr4_+_113066552 0.055 NM_152400
C4orf32
chromosome 4 open reading frame 32
chr3_-_87040246 0.054 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr15_-_27018917 0.053 NM_021912
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr18_+_42260774 0.053 NM_015559
SETBP1
SET binding protein 1
chr9_-_123964337 0.053 NM_016322
RAB14
RAB14, member RAS oncogene family
chr22_-_36635666 0.052 NM_030882
APOL2
apolipoprotein L, 2
chr22_-_36635999 0.051 NM_145637
APOL2
apolipoprotein L, 2
chr12_+_113659216 0.050 NM_001143819
NM_017901
TPCN1

two pore segment channel 1

chr6_+_11538486 0.045 NM_001100829
TMEM170B
transmembrane protein 170B
chr9_-_27529434 0.044 NM_024761
MOB3B
MOB kinase activator 3B
chr3_-_45017600 0.042 NM_001135179
NM_016598
ZDHHC3

zinc finger, DHHC-type containing 3

chr20_+_34700257 0.042 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr4_+_174089889 0.042 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr11_+_121163501 0.041 NM_001024956
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chr14_-_94942513 0.041 NM_001042518
NM_175739
SERPINA9

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9

chr7_+_128379345 0.040 NM_001130674
NM_001199671
NM_001199672
NM_001199673
NM_001199674
NM_001219
CALU





calumenin





chr2_+_192109879 0.040 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr11_+_121163343 0.039 NM_006918
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chr15_-_52821004 0.039 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr20_-_57617836 0.036 NM_016045
SLMO2
slowmo homolog 2 (Drosophila)
chrX_+_18709044 0.036 NM_006240
NM_152224
NM_152226
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr3_-_189838907 0.036 NM_018192
LEPREL1
leprecan-like 1
chr5_-_82373253 0.035 NM_174909
TMEM167A
transmembrane protein 167A
chr11_-_3862183 0.035 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr19_-_48018317 0.035 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr15_+_67358194 0.032 NM_005902
SMAD3
SMAD family member 3
chr2_+_232651059 0.032 NM_022730
COPS7B
COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
chr17_-_29648631 0.031 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr5_-_16936371 0.029 NM_012334
MYO10
myosin X
chr16_+_1203240 0.028 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr19_-_44100127 0.028 NM_001007561
IRGQ
immunity-related GTPase family, Q
chr13_-_73356070 0.027 NM_001128226
NM_014953
DIS3

DIS3 mitotic control homolog (S. cerevisiae)

chr15_+_67418053 0.027 NM_001145102
SMAD3
SMAD family member 3
chr5_-_171881421 0.026 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr1_-_36235422 0.026 NM_001190481
NM_022111
CLSPN

claspin

chr13_+_30002776 0.025 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr15_-_27018216 0.024 NM_000814
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr15_+_67430358 0.023 NM_001145103
SMAD3
SMAD family member 3
chr6_+_45389818 0.023 NM_004348
RUNX2
runt-related transcription factor 2
chr12_+_132379262 0.021 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr11_-_46722115 0.021 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr5_+_176560056 0.020 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr15_+_67458492 0.020 NM_001145104
SMAD3
SMAD family member 3
chr6_-_82462374 0.020 NM_017633
FAM46A
family with sequence similarity 46, member A
chr8_-_67525426 0.019 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr1_-_8003224 0.019 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr6_+_7590405 0.018 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr19_+_42788605 0.018 NM_015125
CIC
capicua homolog (Drosophila)
chr1_+_158149736 0.018 NM_001766
CD1D
CD1d molecule
chr6_+_45296053 0.018 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr5_+_176560627 0.018 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr5_-_95297597 0.018 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr7_+_150147936 0.017 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr7_-_26240366 0.017 NM_002137
NM_031243
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr1_-_151882360 0.017 NM_053055
THEM4
thioesterase superfamily member 4
chr8_+_12803150 0.017 NM_020844
KIAA1456
KIAA1456
chr12_+_32654976 0.017 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr13_-_46425756 0.016 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr1_-_224622000 0.016 NM_001115113
NM_025160
WDR26

WD repeat domain 26

chr2_-_85788644 0.016 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr18_+_55102777 0.016 NM_004852
ONECUT2
one cut homeobox 2
chr7_+_4721722 0.015 NM_001037165
FOXK1
forkhead box K1
chr17_-_77005822 0.015 NM_001159772
NM_001159773
NM_138793
CANT1


calcium activated nucleotidase 1


chr8_+_12869772 0.015 NM_001099677
KIAA1456
KIAA1456
chr16_+_15737123 0.015 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr1_+_231298673 0.014 NM_001004342
TRIM67
tripartite motif containing 67
chr3_-_122233781 0.014 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr9_+_91606349 0.014 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr20_-_34252861 0.014 NM_001198838
NM_001198840
NM_006047
NM_152838
NM_001198863
NM_152925
NM_152926
NM_152927
NM_152928
RBM12



CPNE1




RNA binding motif protein 12



copine I




chr18_+_34409058 0.014 NM_020776
KIAA1328
KIAA1328
chr12_+_56360547 0.013 NM_001798
NM_052827
CDK2

cyclin-dependent kinase 2

chr20_+_37101457 0.013 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr11_+_125439294 0.013 NM_001007277
NM_004879
EI24

etoposide induced 2.4 mRNA

chr3_+_114012832 0.013 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr7_+_128828712 0.013 NM_005631
SMO
smoothened, frizzled family receptor
chr1_+_145096391 0.013 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr4_+_56212381 0.013 NM_024592
SRD5A3
steroid 5 alpha-reductase 3
chr17_-_48785016 0.012 NM_052855
ANKRD40
ankyrin repeat domain 40
chr19_-_2456954 0.012 NM_032737
LMNB2
lamin B2
chr19_+_56915693 0.012 NM_152478
NM_001159861
ZNF583

zinc finger protein 583

chr4_+_1902352 0.012 NM_133334
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr1_+_145524989 0.012 NM_003637
ITGA10
integrin, alpha 10
chr12_+_2162388 0.011 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr19_+_56915382 0.011 NM_001159860
ZNF583
zinc finger protein 583
chr12_-_21487831 0.011 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr1_-_150849211 0.010 NM_001197325
NM_001668
NM_178427
ARNT


aryl hydrocarbon receptor nuclear translocator


chr17_-_8022134 0.010 NM_001165960
ALOXE3
arachidonate lipoxygenase 3
chr10_-_52645430 0.010 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr11_+_18720342 0.010 NM_153347
TMEM86A
transmembrane protein 86A
chr18_+_55019720 0.010 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr4_+_699529 0.010 NM_006315
PCGF3
polycomb group ring finger 3
chr1_-_226187055 0.010 NM_152608
C1orf55
chromosome 1 open reading frame 55
chrX_-_65835845 0.010 NM_001242310
EDA2R
ectodysplasin A2 receptor
chr2_+_97001463 0.009 NM_015341
NCAPH
non-SMC condensin I complex, subunit H
chr20_+_34742656 0.009 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr1_-_173572179 0.009 NM_178527
SLC9A11
solute carrier family 9, member 11
chr18_-_33647336 0.009 NM_018170
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr1_-_201475966 0.009 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr1_-_201476248 0.009 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chrX_-_65859107 0.009 NM_001199687
EDA2R
ectodysplasin A2 receptor
chr12_-_56615484 0.009 NM_001242826
RNF41
ring finger protein 41
chr12_-_56615679 0.009 NM_005785
NM_194358
NM_194359
RNF41


ring finger protein 41


chr22_-_33454328 0.009 NM_001135774
SYN3
synapsin III
chr13_+_50202434 0.009 NM_138450
ARL11
ADP-ribosylation factor-like 11
chr3_+_196295708 0.008 NM_001105573
FBXO45
F-box protein 45
chr16_+_15744082 0.008 NM_017668
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr6_+_34759743 0.008 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr2_+_48757292 0.008 NM_001198595
NM_006873
STON1

stonin 1

chrX_-_65858882 0.008 NM_021783
EDA2R
ectodysplasin A2 receptor
chr8_-_101315457 0.007 NM_015435
RNF19A
ring finger protein 19A
chr12_+_1929432 0.007 NM_001039029
NM_001163925
NM_001163926
LRTM2


leucine-rich repeats and transmembrane domains 2


chr1_-_201465700 0.007 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr17_-_1303548 0.007 NM_006761
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr12_-_53994783 0.007 NM_001130059
ATF7
activating transcription factor 7
chr13_+_29598746 0.006 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2
chr22_+_24951617 0.006 NM_004175
SNRPD3
small nuclear ribonucleoprotein D3 polypeptide 18kDa
chr22_+_36044412 0.005 NM_030641
APOL6
apolipoprotein L, 6
chr17_-_40190043 0.005 NM_001242704
ZNF385C
zinc finger protein 385C
chr20_+_43104513 0.004 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr9_-_38069207 0.004 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr12_-_21548370 0.004 NM_134431
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr12_+_72057676 0.004 NM_031435
THAP2
THAP domain containing, apoptosis associated protein 2
chr13_+_53191601 0.004 NM_001011724
NM_001011725
HNRNPA1L2

heterogeneous nuclear ribonucleoprotein A1-like 2

chr4_+_184020343 0.003 NM_024949
WWC2
WW and C2 domain containing 2
chr6_+_76458888 0.003 NM_004999
MYO6
myosin VI
chr22_-_33402648 0.003 NM_003490
NM_133633
SYN3

synapsin III

chr18_+_77794345 0.003 NM_001171967
NM_024805
RBFA

ribosome binding factor A (putative)

chr11_-_6640661 0.003 NM_000391
TPP1
tripeptidyl peptidase I
chrX_+_146993450 0.002 NM_001185075
NM_001185076
NM_001185081
NM_001185082
NM_002024
FMR1




fragile X mental retardation 1




chr17_-_8021806 0.002 NM_021628
ALOXE3
arachidonate lipoxygenase 3
chr3_+_193310921 0.002 NM_015560
NM_130831
NM_130832
NM_130833
NM_130834
NM_130835
NM_130836
NM_130837
OPA1







optic atrophy 1 (autosomal dominant)







chr4_-_47840058 0.002 NM_006587
CORIN
corin, serine peptidase
chr4_-_113437327 0.002 NM_024019
NEUROG2
neurogenin 2
chr3_+_187943192 0.002 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_206950895 0.001 NM_017759
INO80D
INO80 complex subunit D
chr8_+_59323822 0.001 NM_001077619
UBXN2B
UBX domain protein 2B
chr11_+_109964086 0.001 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr6_+_42788793 0.001 NM_015349
KIAA0240
KIAA0240
chr3_+_143690639 0.000 NM_173552
C3orf58
chromosome 3 open reading frame 58
chr2_+_75873907 0.000 NM_014763
MRPL19
mitochondrial ribosomal protein L19

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.37 2.98e-03 GO:0012505 endomembrane system
1.54 1.02e-02 GO:0044446 intracellular organelle part
1.51 1.62e-02 GO:0044422 organelle part
2.52 4.11e-02 GO:0005794 Golgi apparatus
1.28 4.47e-02 GO:0043229 intracellular organelle
1.28 4.84e-02 GO:0043226 organelle

Nothing significant found in function category.