Motif ID: AAGGUGC

Z-value: 0.637


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
hsa-miR-18a MIMAT0000072
hsa-miR-18b MIMAT0001412
hsa-miR-4735-3p MIMAT0019861



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_132272311 3.110 NM_001901
 CTGF
connective tissue growth factor
chr6_+_112408673 2.558 NM_001033564
 C6orf225
chromosome 6 open reading frame 225
chr13_+_43355685 2.497 NM_182508
 C13orf30
chromosome 13 open reading frame 30
chr4_+_55523906 2.132 NM_000222
NM_001093772
 KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr6_+_39760148 1.443 NM_001201427
 DAAM2
dishevelled associated activator of morphogenesis 2
chr6_+_39760772 1.313 NM_015345
 DAAM2
dishevelled associated activator of morphogenesis 2
chr15_-_61521478 1.203 NM_134261
 RORA
RAR-related orphan receptor A
chr11_-_108464344 1.178 NM_015065
 EXPH5
exophilin 5
chr15_-_60884615 1.116 NM_134262
 RORA
RAR-related orphan receptor A
chr12_+_12764755 0.944 NM_001310
 CREBL2
cAMP responsive element binding protein-like 2
chr15_-_60919642 0.941 NM_002943
NM_134260
 RORA

RAR-related orphan receptor A

chr12_+_104458235 0.920 NM_013320
 HCFC2
host cell factor C2
chr9_-_35563895 0.850 NM_001099951
NM_001164310
 FAM166B

family with sequence similarity 166, member B

chr2_+_63277191 0.829 NM_001199770
 OTX1
orthodenticle homeobox 1
chr5_-_73937248 0.781 NM_003633
 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr2_+_63277936 0.765 NM_014562
 OTX1
orthodenticle homeobox 1
chr1_+_87794150 0.764 NM_006769
 LMO4
LIM domain only 4
chr9_-_74383301 0.675 NM_001135820
NM_013390
 TMEM2

transmembrane protein 2

chr9_+_96338671 0.617 NM_005392
 PHF2
PHD finger protein 2
chr11_-_130184459 0.607 NM_014155
 ZBTB44
zinc finger and BTB domain containing 44

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
4.87 4.97e-02 GO:0040029 regulation of gene expression, epigenetic
1.84 1.17e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.83 1.01e-05 GO:0010468 regulation of gene expression
1.83 3.50e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.81 3.80e-04 GO:0006355 regulation of transcription, DNA-dependent
1.79 1.46e-05 GO:0009889 regulation of biosynthetic process
1.79 3.98e-04 GO:0051252 regulation of RNA metabolic process
1.77 3.80e-05 GO:0031326 regulation of cellular biosynthetic process
1.68 1.28e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 4.33e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.60 3.08e-04 GO:0080090 regulation of primary metabolic process
1.59 3.29e-04 GO:0031323 regulation of cellular metabolic process
1.59 1.06e-03 GO:0060255 regulation of macromolecule metabolic process
1.50 3.82e-03 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.45 7.58e-06 GO:0005634 nucleus
1.22 6.51e-03 GO:0043231 intracellular membrane-bounded organelle
1.22 7.09e-03 GO:0043227 membrane-bounded organelle
1.18 4.14e-02 GO:0043229 intracellular organelle
1.18 4.74e-02 GO:0043226 organelle
1.15 2.32e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.89 8.79e-06 GO:0008270 zinc ion binding
1.75 9.66e-05 GO:0046914 transition metal ion binding
1.58 1.59e-02 GO:0003677 DNA binding
1.50 5.31e-04 GO:0046872 metal ion binding
1.48 9.31e-04 GO:0043169 cation binding
1.48 1.05e-03 GO:0043167 ion binding
1.48 8.61e-03 GO:0003676 nucleic acid binding