Motif ID: AAGUGCU

Z-value: 0.963


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
hsa-miR-302a MIMAT0000684
hsa-miR-302b MIMAT0000715
hsa-miR-302c MIMAT0000717
hsa-miR-302d MIMAT0000718
hsa-miR-302e MIMAT0005931
hsa-miR-372 MIMAT0000724
hsa-miR-373 MIMAT0000726
hsa-miR-520a-3p MIMAT0002834
hsa-miR-520b MIMAT0002843
hsa-miR-520c-3p MIMAT0002846
hsa-miR-520d-3p MIMAT0002856
hsa-miR-520e MIMAT0002825



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_52580805 5.620 NM_001080430
 TOX3
TOX high mobility group box family member 3
chr16_-_52581713 5.390 NM_001146188
 TOX3
TOX high mobility group box family member 3
chr1_-_75139421 3.771 NM_001002912
 C1orf173
chromosome 1 open reading frame 173
chr1_+_183605207 3.449 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr9_-_4300028 3.217 NM_001042413
 GLIS3
GLIS family zinc finger 3
chr6_-_90121966 3.140 NM_021244
 RRAGD
Ras-related GTP binding D
chr9_-_4152182 3.112 NM_152629
 GLIS3
GLIS family zinc finger 3
chr3_-_145968958 2.792 NM_001128306
NM_001177304
NM_020353
 PLSCR4


phospholipid scramblase 4


chr2_+_121103670 2.729 NM_002193
 INHBB
inhibin, beta B
chr10_+_115803805 2.616 NM_000684
 ADRB1
adrenergic, beta-1-, receptor
chr9_-_124984018 2.551 NM_001242335
 LHX6
LIM homeobox 6
chr9_-_124990949 2.425 NM_014368
NM_199160
 LHX6

LIM homeobox 6

chr1_+_61547625 2.403 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr5_-_134914968 2.378 NM_004887
 CXCL14
chemokine (C-X-C motif) ligand 14
chr9_-_124990706 2.308 NM_001242333
 LHX6
LIM homeobox 6
chr1_+_61542928 2.255 NM_001145511
 NFIA
nuclear factor I/A
chr15_-_93632161 2.087 NM_020211
 RGMA
RGM domain family, member A
chr15_-_93616891 2.044 NM_001166288
NM_001166289
 RGMA

RGM domain family, member A

chr9_+_74729510 2.038 NM_001242507
 GDA
guanine deaminase
chr15_-_93617091 1.925 NM_001166283
 RGMA
RGM domain family, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
3.76 3.25e-02 GO:0007156 homophilic cell adhesion
2.83 4.89e-03 GO:0070647 protein modification by small protein conjugation or removal
2.70 4.68e-05 GO:0051253 negative regulation of RNA metabolic process
2.69 8.40e-05 GO:0045892 negative regulation of transcription, DNA-dependent
2.58 6.89e-05 GO:0010629 negative regulation of gene expression
2.42 7.96e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.39 1.09e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.37 1.29e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.37 2.66e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.33 1.48e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.29 1.62e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.24 2.72e-03 GO:0009890 negative regulation of biosynthetic process
2.19 1.96e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.18 3.95e-04 GO:0006351 transcription, DNA-dependent
2.16 1.32e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.15 5.87e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.10 8.07e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.10 3.66e-02 GO:0051254 positive regulation of RNA metabolic process
2.10 4.87e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.08 4.51e-02 GO:0010628 positive regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
2.13 1.19e-03 GO:0044451 nucleoplasm part
1.78 1.81e-03 GO:0005654 nucleoplasm
1.68 5.41e-04 GO:0031981 nuclear lumen
1.61 2.43e-15 GO:0005634 nucleus
1.59 1.57e-03 GO:0044428 nuclear part
1.25 1.41e-07 GO:0043229 intracellular organelle
1.25 1.83e-07 GO:0043226 organelle
1.25 2.30e-05 GO:0043231 intracellular membrane-bounded organelle
1.25 2.61e-05 GO:0043227 membrane-bounded organelle
1.17 5.97e-05 GO:0005622 intracellular
1.16 4.23e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
5.99 1.43e-02 GO:0042054 histone methyltransferase activity
5.87 5.75e-03 GO:0004879 ligand-dependent nuclear receptor activity
5.52 2.61e-02 GO:0003707 steroid hormone receptor activity
5.28 1.37e-02 GO:0008276 protein methyltransferase activity
3.41 1.92e-03 GO:0003682 chromatin binding
3.05 1.54e-04 GO:0016564 transcription repressor activity
2.35 6.03e-05 GO:0043565 sequence-specific DNA binding
2.35 8.55e-03 GO:0004674 protein serine/threonine kinase activity
2.27 7.22e-07 GO:0001071 nucleic acid binding transcription factor activity
2.27 7.22e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
2.18 4.50e-06 GO:0030528 transcription regulator activity
2.06 1.60e-11 GO:0008270 zinc ion binding
2.06 1.87e-02 GO:0004672 protein kinase activity
1.94 9.39e-11 GO:0003677 DNA binding
1.86 6.38e-09 GO:0046914 transition metal ion binding
1.75 6.25e-11 GO:0003676 nucleic acid binding
1.63 1.07e-09 GO:0046872 metal ion binding
1.62 1.72e-09 GO:0043167 ion binding
1.61 2.80e-09 GO:0043169 cation binding
1.14 3.89e-03 GO:0005488 binding