Motif ID: AAUACUG

Z-value: 1.799


Mature miRNA associated with seed AAUACUG:

NamemiRBase Accession
hsa-miR-200b MIMAT0000318
hsa-miR-200c MIMAT0000617
hsa-miR-429 MIMAT0001536



Activity profile for motif AAUACUG.

activity profile for motif AAUACUG


Sorted Z-values histogram for motif AAUACUG

Sorted Z-values for motif AAUACUG



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUACUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_30655671 6.811 NM_133471
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr6_-_30655078 6.259 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr10_+_102106771 6.095 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr7_+_5632435 5.781 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr18_-_21166440 5.234 NM_000271
NPC1
Niemann-Pick disease, type C1
chr2_+_210444364 5.164 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr2_+_210288668 4.864 NM_001039538
MAP2
microtubule-associated protein 2
chrX_+_64887510 4.839 NM_002444
MSN
moesin
chr11_-_128457452 4.631 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr15_-_64673569 4.414 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr1_-_8086392 4.325 NM_018948
ERRFI1
ERBB receptor feedback inhibitor 1
chr11_-_128392061 4.291 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr9_+_34990266 4.250 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_+_11886739 4.236 NM_145693
LPIN1
lipin 1
chr18_+_56530060 4.120 NM_018181
ZNF532
zinc finger protein 532
chr7_+_36429388 3.854 NM_018685
ANLN
anillin, actin binding protein
chr2_+_102314162 3.665 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr9_+_34989637 3.637 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr1_+_182992329 3.473 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr12_-_52585686 3.383 NM_001081492
NM_182507
KRT80

keratin 80

chr9_+_112887780 3.355 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr17_+_16945766 3.353 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr1_+_178694273 3.283 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr2_+_208576239 3.217 NM_001142300
NM_152523
CCNYL1

cyclin Y-like 1

chr11_+_119076974 3.166 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr16_+_8806825 3.145 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr21_-_16437125 3.121 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr7_-_73133917 3.081 NM_001165903
NM_004603
STX1A

syntaxin 1A (brain)

chr3_-_52090090 3.059 NM_001947
DUSP7
dual specificity phosphatase 7
chr7_-_28220342 3.038 NM_175061
JAZF1
JAZF zinc finger 1
chr12_+_1800188 2.985 NM_024551
ADIPOR2
adiponectin receptor 2
chr5_-_112824526 2.983 NM_001085377
MCC
mutated in colorectal cancers
chr9_+_112810877 2.977 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr10_-_14372807 2.913 NM_018027
FRMD4A
FERM domain containing 4A
chr3_+_150126705 2.828 NM_014779
TSC22D2
TSC22 domain family, member 2
chr1_+_230202928 2.815 NM_004481
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr16_+_8814567 2.797 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr1_+_84630575 2.771 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr13_-_30881556 2.761 NM_032116
KATNAL1
katanin p60 subunit A-like 1
chr2_-_216300770 2.728 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr5_-_112630557 2.684 NM_002387
MCC
mutated in colorectal cancers
chr2_-_9143742 2.665 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr3_-_27498244 2.655 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_-_76921453 2.609 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr6_+_163835668 2.548 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr9_+_706744 2.524 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_201252579 2.499 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr1_-_208417635 2.453 NM_025179
PLXNA2
plexin A2
chr17_-_42907606 2.444 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr22_+_21271619 2.444 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_110091185 2.442 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr9_-_34458477 2.435 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184945
NM_147202
C9orf25





chromosome 9 open reading frame 25





chr9_+_112542496 2.433 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr6_+_106534188 2.407 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_117210301 2.401 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr9_+_128510477 2.396 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3
chr9_+_128509616 2.381 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr9_-_113800243 2.339 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr13_-_30881141 2.337 NM_001014380
KATNAL1
katanin p60 subunit A-like 1
chr3_+_50192847 2.325 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_-_123339423 2.309 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr6_+_20402040 2.299 NM_001949
E2F3
E2F transcription factor 3
chr1_-_231560789 2.273 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr12_+_57522247 2.248 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr6_-_108395939 2.235 NM_014028
OSTM1
osteopetrosis associated transmembrane protein 1
chr1_+_84609941 2.232 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_+_43737937 2.229 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr1_+_25071759 2.216 NM_013943
CLIC4
chloride intracellular channel 4
chr1_+_84630014 2.204 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr7_+_130131921 2.169 NM_002402
MEST
mesoderm specific transcript homolog (mouse)
chr6_-_10415438 2.146 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr13_-_40177355 2.119 NM_005780
LHFP
lipoma HMGIC fusion partner
chr8_+_86376130 2.097 NM_000067
CA2
carbonic anhydrase II
chr12_-_109125289 2.093 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr14_-_35183722 2.084 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr9_+_504661 2.060 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_84647342 2.037 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_35182944 2.037 NM_021914
CFL2
cofilin 2 (muscle)
chr5_+_149887673 2.016 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_-_22307212 2.005 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr1_+_77333158 1.978 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_-_122406994 1.965 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr7_+_130126035 1.953 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr17_-_53499055 1.944 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr17_-_42908178 1.931 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr8_+_22224997 1.926 NM_001135153
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr11_+_118477212 1.917 NM_015157
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr17_-_49198084 1.906 NM_001130527
NM_001130528
NM_003971
SPAG9


sperm associated antigen 9


chr19_-_11308184 1.905 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chrX_-_131351917 1.898 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr12_+_13349601 1.878 NM_001423
EMP1
epithelial membrane protein 1
chr1_-_175161832 1.865 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr19_-_11305186 1.853 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr8_+_8860313 1.852 NM_153332
ERI1
exoribonuclease 1
chr3_-_98620452 1.847 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr3_+_121902529 1.829 NM_000388
CASR
calcium-sensing receptor
chr6_-_10419786 1.812 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr7_+_130131172 1.807 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr7_-_98741681 1.805 NM_001199847
NM_020429
NM_181349
SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr11_+_33060962 1.795 NM_018393
TCP11L1
t-complex 11 (mouse)-like 1
chr2_-_37193609 1.782 NM_003162
STRN
striatin, calmodulin binding protein
chr6_+_106546736 1.781 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr2_+_228336877 1.769 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chr11_+_33061560 1.762 NM_001145541
TCP11L1
t-complex 11 (mouse)-like 1
chr16_+_8768403 1.752 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr13_-_33859835 1.745 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr22_-_36424397 1.733 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr4_-_122744978 1.731 NM_001237
CCNA2
cyclin A2
chr11_+_118478305 1.709 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr6_+_114178516 1.674 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_+_5629110 1.670 NM_001135920
NM_001206557
NM_020829
KIAA1432


KIAA1432


chr8_+_32579350 1.660 NM_001159996
NRG1
neuregulin 1
chr12_-_106641675 1.637 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr22_-_36236421 1.624 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr10_+_96162185 1.618 NM_015188
TBC1D12
TBC1 domain family, member 12
chr12_+_120105656 1.617 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr8_-_82024277 1.605 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr3_-_123603144 1.594 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr9_+_131644780 1.573 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr8_+_70405027 1.571 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr6_-_10412606 1.568 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_-_120514669 1.563 NM_153810
C10orf46
chromosome 10 open reading frame 46
chr17_-_79885544 1.552 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr12_+_56324945 1.517 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr19_-_40791291 1.512 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr10_-_23003443 1.511 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr15_+_40509628 1.511 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr2_+_201170603 1.510 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr2_-_47143250 1.504 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr17_-_71640226 1.498 NM_001144952
SDK2
sidekick cell adhesion molecule 2
chr7_+_4721722 1.493 NM_001037165
FOXK1
forkhead box K1
chrX_-_54522318 1.490 NM_004463
FGD1
FYVE, RhoGEF and PH domain containing 1
chr3_+_44379923 1.483 NM_001029839
NM_173826
C3orf23

chromosome 3 open reading frame 23

chr19_+_34287662 1.477 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr9_+_131644368 1.474 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr14_-_39572414 1.473 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr13_-_74707913 1.471 NM_007249
KLF12
Kruppel-like factor 12
chr1_-_120190389 1.471 NM_001080470
ZNF697
zinc finger protein 697
chr11_+_128563772 1.466 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr5_+_38845962 1.465 NM_003999
OSMR
oncostatin M receptor
chr4_-_153303663 1.456 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr7_+_77167351 1.439 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr3_-_185826748 1.415 NM_004454
ETV5
ets variant 5
chr4_-_139163222 1.403 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr8_+_90769974 1.392 NM_003821
RIPK2
receptor-interacting serine-threonine kinase 2
chr13_-_33760215 1.391 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr9_+_132815984 1.381 NM_001136557
NM_001136558
NM_020960
GPR107


G protein-coupled receptor 107


chr10_-_105614952 1.376 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr9_+_112403067 1.373 NM_001037293
PALM2
paralemmin 2
chr9_-_139440237 1.368 NM_017617
NOTCH1
notch 1
chr13_-_33780142 1.367 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr3_-_120169493 1.366 NM_007085
FSTL1
follistatin-like 1
chr1_-_214724974 1.365 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr7_-_42276617 1.364 NM_000168
GLI3
GLI family zinc finger 3
chr22_-_50913270 1.352 NM_002972
SBF1
SET binding factor 1
chr7_+_28338939 1.341 NM_182899
CREB5
cAMP responsive element binding protein 5
chr12_+_26205490 1.339 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr10_-_99052429 1.338 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr4_-_176923572 1.332 NM_005277
NM_201592
GPM6A

glycoprotein M6A

chr10_-_101945686 1.331 NM_006459
ERLIN1
ER lipid raft associated 1
chr13_-_21635703 1.321 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr2_-_47142950 1.312 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr2_+_198669316 1.294 NM_006226
PLCL1
phospholipase C-like 1
chr3_+_158991035 1.291 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr12_+_79439432 1.277 NM_001135806
SYT1
synaptotagmin I
chr12_-_51591949 1.273 NM_002702
POU6F1
POU class 6 homeobox 1
chr10_-_101945787 1.269 NM_001100626
ERLIN1
ER lipid raft associated 1
chr5_+_70751435 1.252 NM_018429
BDP1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chrX_+_150151757 1.243 NM_005342
HMGB3
high mobility group box 3
chr3_-_15140652 1.237 NM_022340
ZFYVE20
zinc finger, FYVE domain containing 20
chr16_-_67281398 1.236 NM_013241
FHOD1
formin homology 2 domain containing 1
chr7_+_138916230 1.229 NM_173569
UBN2
ubinuclein 2
chr2_+_201170795 1.227 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr12_+_26126687 1.222 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr11_-_46939908 1.222 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr8_+_106331146 1.220 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr14_-_99737821 1.219 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr2_+_23608297 1.218 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr14_+_55518313 1.210 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr7_+_77166750 1.208 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr7_+_28725597 1.197 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr21_-_15755439 1.192 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr9_-_23826062 1.191 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr19_-_18632886 1.181 NM_006532
ELL
elongation factor RNA polymerase II
chr11_-_35441099 1.180 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_-_156272909 1.173 NM_007107
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr15_+_72766665 1.170 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)
chr5_-_171433876 1.162 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr17_-_56084656 1.159 NM_001078166
NM_006924
SRSF1

serine/arginine-rich splicing factor 1

chr5_+_7396030 1.156 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr8_+_32405727 1.155 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr13_-_107187312 1.121 NM_004093
EFNB2
ephrin-B2
chr2_-_47168902 1.119 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chr21_+_40177847 1.113 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr4_-_73434467 1.100 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chrX_-_15873094 1.099 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr8_+_11561710 1.095 NM_002052
GATA4
GATA binding protein 4
chr4_-_68566847 1.089 NM_018227
UBA6
ubiquitin-like modifier activating enzyme 6
chr1_-_225616556 1.081 NM_194442
LBR
lamin B receptor
chr9_+_33817168 1.073 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.59e-10 GO:0050794 regulation of cellular process
1.34 2.64e-10 GO:0065007 biological regulation
1.36 3.11e-10 GO:0050789 regulation of biological process
1.21 2.11e-09 GO:0009987 cellular process
1.58 1.15e-08 GO:0031323 regulation of cellular metabolic process
1.58 2.18e-08 GO:0080090 regulation of primary metabolic process
1.53 3.42e-08 GO:0019222 regulation of metabolic process
1.58 1.13e-07 GO:0060255 regulation of macromolecule metabolic process
1.50 1.69e-06 GO:0023052 signaling
1.71 1.73e-06 GO:0048523 negative regulation of cellular process
1.62 1.96e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 2.75e-06 GO:0044260 cellular macromolecule metabolic process
1.58 8.50e-06 GO:0051171 regulation of nitrogen compound metabolic process
2.37 1.21e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.50 1.59e-05 GO:0007165 signal transduction
1.61 2.87e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.56 7.10e-05 GO:0031326 regulation of cellular biosynthetic process
2.47 7.17e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.44 1.22e-04 GO:0032502 developmental process
1.59 1.28e-04 GO:0048519 negative regulation of biological process
1.57 1.41e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.54 1.43e-04 GO:0009889 regulation of biosynthetic process
1.56 1.49e-04 GO:0010468 regulation of gene expression
1.35 2.34e-04 GO:0043170 macromolecule metabolic process
1.45 2.76e-04 GO:0007275 multicellular organismal development
1.58 4.16e-04 GO:0051252 regulation of RNA metabolic process
1.74 4.48e-04 GO:0007399 nervous system development
2.52 5.44e-04 GO:0007409 axonogenesis
2.73 5.78e-04 GO:0007411 axon guidance
1.99 6.25e-04 GO:0006351 transcription, DNA-dependent
1.73 6.84e-04 GO:0009653 anatomical structure morphogenesis
1.50 8.01e-04 GO:0048518 positive regulation of biological process
1.54 8.43e-04 GO:0048522 positive regulation of cellular process
2.34 1.23e-03 GO:0031175 neuron projection development
1.67 1.27e-03 GO:0023051 regulation of signaling
2.43 1.31e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.32 1.64e-03 GO:0000904 cell morphogenesis involved in differentiation
2.40 1.77e-03 GO:0010648 negative regulation of cell communication
2.30 1.94e-03 GO:0048858 cell projection morphogenesis
2.39 2.00e-03 GO:0048812 neuron projection morphogenesis
2.14 2.32e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.28 2.42e-03 GO:0032990 cell part morphogenesis
2.01 2.97e-03 GO:2000026 regulation of multicellular organismal development
2.14 3.24e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69 3.76e-03 GO:0009966 regulation of signal transduction
2.98 3.80e-03 GO:0048011 nerve growth factor receptor signaling pathway
2.14 3.89e-03 GO:0000902 cell morphogenesis
2.10 4.13e-03 GO:0030030 cell projection organization
2.34 4.45e-03 GO:0023057 negative regulation of signaling
2.11 4.53e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.53 4.93e-03 GO:0006355 regulation of transcription, DNA-dependent
1.85 4.97e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.39 5.78e-03 GO:0009968 negative regulation of signal transduction
1.42 6.25e-03 GO:0048856 anatomical structure development
1.87 6.99e-03 GO:0031324 negative regulation of cellular metabolic process
1.58 7.29e-03 GO:0006464 protein modification process
2.05 7.86e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.03 8.12e-03 GO:0010628 positive regulation of gene expression
1.25 8.57e-03 GO:0044237 cellular metabolic process
1.85 9.80e-03 GO:0050793 regulation of developmental process
2.01 1.05e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.74 1.07e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.34 1.11e-02 GO:0051716 cellular response to stimulus
2.05 1.15e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.19 1.16e-02 GO:0048585 negative regulation of response to stimulus
1.54 1.37e-02 GO:0043412 macromolecule modification
2.00 1.39e-02 GO:0051254 positive regulation of RNA metabolic process
1.56 1.44e-02 GO:0010467 gene expression
2.03 1.50e-02 GO:0032989 cellular component morphogenesis
1.69 1.57e-02 GO:0009893 positive regulation of metabolic process
1.57 1.62e-02 GO:0016070 RNA metabolic process
1.56 1.71e-02 GO:0007166 cell surface receptor linked signaling pathway
1.66 1.72e-02 GO:0035556 intracellular signal transduction
1.80 1.74e-02 GO:0032774 RNA biosynthetic process
2.18 1.78e-02 GO:0043549 regulation of kinase activity
1.92 1.80e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 1.82e-02 GO:0048731 system development
1.96 1.83e-02 GO:0009890 negative regulation of biosynthetic process
2.07 1.93e-02 GO:0048666 neuron development
4.26 1.95e-02 GO:0060485 mesenchyme development
1.82 1.99e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.82 1.99e-02 GO:0022008 neurogenesis
1.81 2.55e-02 GO:0048468 cell development
1.69 2.75e-02 GO:0031325 positive regulation of cellular metabolic process
1.24 2.93e-02 GO:0044238 primary metabolic process
1.83 2.99e-02 GO:0048699 generation of neurons
1.53 3.02e-02 GO:0048583 regulation of response to stimulus
2.07 3.38e-02 GO:0051253 negative regulation of RNA metabolic process
2.10 3.88e-02 GO:0051338 regulation of transferase activity
1.86 4.05e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
2.27 4.13e-02 GO:0007264 small GTPase mediated signal transduction
2.15 4.20e-02 GO:0045859 regulation of protein kinase activity
1.60 4.28e-02 GO:0065009 regulation of molecular function
1.75 4.92e-02 GO:0009892 negative regulation of metabolic process
1.87 4.95e-02 GO:0010557 positive regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 6.48e-09 GO:0005622 intracellular
1.19 8.70e-09 GO:0044424 intracellular part
1.35 1.67e-06 GO:0005634 nucleus
1.19 1.59e-05 GO:0043229 intracellular organelle
1.19 2.08e-05 GO:0043226 organelle
1.21 3.92e-05 GO:0043231 intracellular membrane-bounded organelle
1.21 4.54e-05 GO:0043227 membrane-bounded organelle
1.21 2.52e-04 GO:0005737 cytoplasm
1.07 6.20e-04 GO:0044464 cell part
1.07 6.32e-04 GO:0005623 cell
6.40 7.34e-04 GO:0008287 protein serine/threonine phosphatase complex
1.56 1.31e-03 GO:0031981 nuclear lumen
1.50 2.25e-03 GO:0044428 nuclear part
1.50 3.08e-03 GO:0005829 cytosol
1.65 3.58e-03 GO:0005654 nucleoplasm
8.74 1.16e-02 GO:0000159 protein phosphatase type 2A complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.31 3.16e-08 GO:0005515 protein binding
1.15 1.04e-05 GO:0005488 binding
1.84 7.92e-04 GO:0001071 nucleic acid binding transcription factor activity
1.84 7.92e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.14 1.53e-03 GO:0008092 cytoskeletal protein binding
2.49 6.41e-03 GO:0005083 small GTPase regulator activity
2.39 9.58e-03 GO:0016563 transcription activator activity
1.36 9.77e-03 GO:0003676 nucleic acid binding
1.71 1.28e-02 GO:0030528 transcription regulator activity
1.74 1.29e-02 GO:0030234 enzyme regulator activity
3.08 1.77e-02 GO:0003714 transcription corepressor activity
1.84 3.21e-02 GO:0043565 sequence-specific DNA binding
2.01 3.43e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.01 4.53e-02 GO:0030695 GTPase regulator activity