Motif ID: AAUGCCC

Z-value: 0.667


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_149363498 2.191 NM_000901
NM_001166104
 NR3C2

nuclear receptor subfamily 3, group C, member 2

chr20_+_9049660 1.578 NM_001172646
 PLCB4
phospholipase C, beta 4
chr20_+_9288446 1.498 NM_000933
 PLCB4
phospholipase C, beta 4
chr20_+_9198036 1.405 NM_182797
 PLCB4
phospholipase C, beta 4
chr16_+_19467771 1.402 NM_024780
 TMC5
transmembrane channel-like 5
chr1_+_61547625 1.343 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr20_-_39317875 1.288 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_+_61542928 1.287 NM_001145511
 NFIA
nuclear factor I/A
chr6_-_134496006 1.202 NM_005627
 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134497069 1.182 NM_001143678
 SGK1
serum/glucocorticoid regulated kinase 1
chr9_-_117156684 1.132 NM_030767
 AKNA
AT-hook transcription factor
chr5_+_149109814 1.120 NM_001172698
NM_133263
 PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr16_+_19422056 1.111 NM_001105248
NM_001105249
 TMC5

transmembrane channel-like 5

chr5_+_149151502 1.103 NM_001172699
 PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr1_+_61547388 1.069 NM_001145512
 NFIA
nuclear factor I/A
chr12_-_89918531 1.058 NM_003774
 GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr6_-_134639195 1.042 NM_001143676
 SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134498973 1.038 NM_001143677
 SGK1
serum/glucocorticoid regulated kinase 1
chr20_+_37434294 0.821 NM_001172735
NM_015568
 PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr3_+_23986735 0.820 NM_005126
 NR1D2
nuclear receptor subfamily 1, group D, member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
5.76 2.85e-02 GO:0003001 generation of a signal involved in cell-cell signaling
5.76 2.85e-02 GO:0023061 signal release
4.44 4.29e-02 GO:0016570 histone modification
3.64 2.86e-03 GO:0016568 chromatin modification
3.49 1.58e-06 GO:0051254 positive regulation of RNA metabolic process
3.38 2.05e-05 GO:0045893 positive regulation of transcription, DNA-dependent
3.31 1.90e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.23 5.45e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
3.23 3.03e-05 GO:0010628 positive regulation of gene expression
3.18 8.33e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.08 1.71e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
3.05 7.30e-06 GO:0031328 positive regulation of cellular biosynthetic process
3.01 2.29e-02 GO:0006325 chromatin organization
3.00 1.12e-05 GO:0009891 positive regulation of biosynthetic process
2.68 3.08e-02 GO:0051276 chromosome organization
2.61 2.46e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.54 5.34e-05 GO:0031325 positive regulation of cellular metabolic process
2.52 2.97e-05 GO:0009893 positive regulation of metabolic process
2.47 2.44e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.00 2.75e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.80 1.64e-04 GO:0044451 nucleoplasm part
2.49 2.07e-06 GO:0005654 nucleoplasm
2.00 2.55e-04 GO:0031981 nuclear lumen
1.80 2.66e-03 GO:0044428 nuclear part
1.70 1.53e-02 GO:0070013 intracellular organelle lumen
1.67 2.56e-02 GO:0043233 organelle lumen
1.64 3.85e-02 GO:0031974 membrane-enclosed lumen
1.53 1.50e-05 GO:0005634 nucleus
1.26 5.95e-03 GO:0043231 intracellular membrane-bounded organelle
1.26 6.40e-03 GO:0043227 membrane-bounded organelle
1.25 2.33e-03 GO:0043229 intracellular organelle
1.25 2.66e-03 GO:0043226 organelle
1.19 5.36e-03 GO:0044424 intracellular part
1.17 1.47e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
7.98 2.32e-02 GO:0003707 steroid hormone receptor activity
7.54 3.20e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.76 3.97e-02 GO:0004674 protein serine/threonine kinase activity
2.46 3.52e-02 GO:0004672 protein kinase activity
2.36 2.19e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.19 1.10e-02 GO:0001071 nucleic acid binding transcription factor activity
2.19 1.10e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.07 4.07e-02 GO:0030528 transcription regulator activity
1.40 7.23e-05 GO:0005515 protein binding
1.17 1.89e-02 GO:0005488 binding