Motif ID: ACAGUAC

Z-value: 0.801


Mature miRNA associated with seed ACAGUAC:

NamemiRBase Accession
hsa-miR-101 MIMAT0000099



Activity profile for motif ACAGUAC.

activity profile for motif ACAGUAC


Sorted Z-values histogram for motif ACAGUAC

Sorted Z-values for motif ACAGUAC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_163149001 1.475 NM_001080379
PACRG
PARK2 co-regulated
chr6_+_163148163 1.454 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr8_-_23712297 1.443 NM_003155
STC1
stanniocalcin 1
chr3_+_3841079 1.333 NM_020873
LRRN1
leucine rich repeat neuronal 1
chrY_+_15016018 1.318 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_+_115803805 1.298 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr7_-_148580600 0.891 NM_001203249
EZH2
enhancer of zeste homolog 2 (Drosophila)
chrY_+_15016698 0.861 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr11_-_115375065 0.858 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_-_186649421 0.818 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_148581403 0.815 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr1_-_204459445 0.806 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr5_+_149151502 0.796 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_151815174 0.791 NM_025059
C6orf97
chromosome 6 open reading frame 97
chr5_+_149109814 0.745 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr20_+_11898536 0.739 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr8_+_75896707 0.695 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr2_-_217560247 0.693 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr2_-_99771186 0.657 NM_025244
TSGA10
testis specific, 10
chr2_-_99758034 0.642 NM_182911
TSGA10
testis specific, 10
chr12_+_56414688 0.631 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr8_+_40010986 0.618 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr11_-_74660165 0.555 NM_182969
XRRA1
X-ray radiation resistance associated 1
chr2_+_220094478 0.553 NM_018089
NM_001042410
ANKZF1

ankyrin repeat and zinc finger domain containing 1

chr7_+_73442426 0.544 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr6_+_143929316 0.540 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr3_+_88188261 0.537 NM_018293
ZNF654
zinc finger protein 654
chr6_+_143999058 0.535 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr10_+_76586299 0.532 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr14_+_45431333 0.532 NM_015091
FAM179B
family with sequence similarity 179, member B
chr19_+_10543110 0.526 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_+_135502445 0.518 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr1_+_244214552 0.506 NM_205768
ZNF238
zinc finger protein 238
chr13_-_61989654 0.503 NM_022843
PCDH20
protocadherin 20
chr17_+_60556247 0.494 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr2_+_191273012 0.492 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr20_+_11871364 0.489 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr1_+_244216506 0.466 NM_006352
ZNF238
zinc finger protein 238
chr6_-_111804413 0.453 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr10_-_94050799 0.450 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr8_-_72268720 0.443 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr19_+_10563581 0.442 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_+_107811272 0.438 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr7_-_44887697 0.434 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr9_-_14398981 0.425 NM_001190738
NFIB
nuclear factor I/B
chr5_+_127419407 0.421 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr5_-_59783885 0.418 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_93963597 0.418 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr5_+_153825497 0.417 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr4_+_72052354 0.416 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr10_+_97889467 0.408 NM_014803
ZNF518A
zinc finger protein 518A
chr14_-_61190458 0.404 NM_017420
SIX4
SIX homeobox 4
chr1_+_183605207 0.400 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr9_-_14314036 0.396 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr3_+_23986735 0.392 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr21_+_35445808 0.388 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr4_+_106816593 0.385 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr8_-_56685869 0.383 NM_152417
TMEM68
transmembrane protein 68
chr5_-_58571916 0.382 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_72274466 0.373 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr10_-_94003002 0.372 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr4_-_141075232 0.369 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr6_-_10838712 0.367 NM_001242385
NM_001242957
NM_005906
MAK


male germ cell-associated kinase


chr1_-_47779651 0.365 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr1_-_169455099 0.360 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr5_-_59189620 0.360 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_23987514 0.358 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr16_+_14164879 0.357 NM_014048
MKL2
MKL/myocardin-like 2
chr19_+_10541334 0.354 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_+_35937351 0.351 NM_014310
RASD2
RASD family, member 2
chr12_+_111843743 0.347 NM_005475
SH2B3
SH2B adaptor protein 3
chr15_+_33603162 0.346 NM_001036
NM_001243996
RYR3

ryanodine receptor 3

chr1_+_179923870 0.346 NM_014810
CEP350
centrosomal protein 350kDa
chr6_+_33387846 0.343 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr1_-_173962050 0.343 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr4_+_72204769 0.341 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr18_-_53255734 0.341 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr20_+_61427804 0.337 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr11_-_70507911 0.334 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_+_220701547 0.332 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr6_-_52926588 0.331 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr14_-_65438794 0.329 NM_198686
RAB15
RAB15, member RAS onocogene family
chr19_-_33793429 0.326 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr22_+_47022657 0.325 NM_015124
GRAMD4
GRAM domain containing 4
chr2_+_74056042 0.321 NM_201647
STAMBP
STAM binding protein
chr1_-_86043932 0.317 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_-_112726143 0.313 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr19_+_10531128 0.305 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_-_95657255 0.305 NM_001243571
NM_016156
NM_201278
NM_201281
MTMR2



myotubularin related protein 2



chr3_-_183273407 0.296 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_-_197169635 0.292 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr2_+_74056095 0.288 NM_006463
NM_213622
STAMBP

STAM binding protein

chr10_+_120789227 0.282 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chrX_+_106449861 0.282 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr20_+_51801821 0.282 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr15_-_51914770 0.279 NM_001174116
NM_001174117
NM_015263
DMXL2


Dmx-like 2


chr15_-_37391596 0.277 NM_172316
MEIS2
Meis homeobox 2
chr15_-_59225800 0.277 NM_001013843
NM_024755
SLTM

SAFB-like, transcription modulator

chr5_-_58295758 0.276 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_37390372 0.275 NM_172315
MEIS2
Meis homeobox 2
chr17_-_63557615 0.275 NM_004655
AXIN2
axin 2
chr20_+_51588945 0.275 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr11_-_70935807 0.274 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_-_85930733 0.265 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_+_75898836 0.262 NM_001135049
JDP2
Jun dimerization protein 2
chr2_+_46926049 0.261 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr8_-_74659082 0.261 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr20_+_58515408 0.261 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr16_+_58059281 0.261 NM_002428
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr10_-_105614952 0.260 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr7_+_100026412 0.260 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr5_+_137688270 0.260 NM_016604
KDM3B
lysine (K)-specific demethylase 3B
chr3_+_143692166 0.252 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr4_+_15004297 0.251 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr4_-_18023358 0.246 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr14_+_75894919 0.246 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr8_+_110346549 0.242 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr12_-_76478737 0.237 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr16_-_1429612 0.236 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr7_+_8008416 0.235 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr8_+_17354562 0.235 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chrX_-_19988381 0.235 NM_198279
CXorf23
chromosome X open reading frame 23
chr17_-_65241305 0.234 NM_014877
HELZ
helicase with zinc finger
chr7_+_120590816 0.231 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chrX_-_128657453 0.231 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr15_-_37393364 0.229 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr1_+_205473683 0.225 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr14_-_57735614 0.222 NM_006544
EXOC5
exocyst complex component 5
chr5_-_40798263 0.222 NM_006251
NM_206907
PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

chr16_-_74808699 0.219 NM_024306
FA2H
fatty acid 2-hydroxylase
chr15_-_37392358 0.219 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr7_+_100027253 0.218 NM_019606
MEPCE
methylphosphate capping enzyme
chr14_+_75894508 0.216 NM_001135047
JDP2
Jun dimerization protein 2
chr2_-_20527120 0.215 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr4_+_38665587 0.213 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr2_+_198380294 0.213 NM_199482
MOB4
MOB family member 4, phocein
chr6_-_82462374 0.213 NM_017633
FAM46A
family with sequence similarity 46, member A
chr5_+_141488314 0.212 NM_030571
NDFIP1
Nedd4 family interacting protein 1
chr3_-_69101236 0.211 NM_007114
TMF1
TATA element modulatory factor 1
chr6_+_19837599 0.209 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chrX_-_108976509 0.209 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr19_-_31840118 0.209 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr3_-_15839674 0.208 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr9_+_101867401 0.207 NM_001130916
NM_004612
TGFBR1

transforming growth factor, beta receptor 1

chr5_-_58652671 0.207 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_38495778 0.206 NM_001106
ACVR2B
activin A receptor, type IIB
chr11_+_121322848 0.205 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr6_-_33168369 0.205 NM_021976
RXRB
retinoid X receptor, beta
chr2_+_46926323 0.202 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr20_+_58508818 0.201 NM_001190826
C20orf177
chromosome 20 open reading frame 177
chr21_+_18885104 0.201 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr12_+_19592311 0.200 NM_001114176
NM_153207
AEBP2

AE binding protein 2

chr1_+_82266081 0.200 NM_012302
LPHN2
latrophilin 2
chr2_-_24149899 0.200 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr6_+_138483024 0.200 NM_020340
KIAA1244
KIAA1244
chr6_-_13711643 0.200 NM_005493
RANBP9
RAN binding protein 9
chr5_-_114880536 0.199 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr15_+_100173182 0.198 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr2_+_198381021 0.197 NM_001204094
MOB4
MOB family member 4, phocein
chr16_+_67596309 0.193 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr8_+_136469557 0.193 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr2_-_68479481 0.192 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr8_+_17396285 0.192 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr8_+_79578258 0.191 NM_016010
FAM164A
family with sequence similarity 164, member A
chr6_-_35464716 0.190 NM_003214
TEAD3
TEA domain family member 3
chr16_+_71879893 0.189 NM_001137675
ATXN1L
ataxin 1-like
chr18_-_812268 0.189 NM_005433
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr16_+_19125243 0.189 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr15_-_60884615 0.188 NM_134262
RORA
RAR-related orphan receptor A
chr21_-_27543134 0.186 NM_000484
NM_001136129
NM_001136130
NM_001204301
NM_001204302
NM_001204303
NM_201413
NM_201414
APP







amyloid beta (A4) precursor protein







chr8_-_124553448 0.185 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr7_-_44924946 0.185 NM_033224
PURB
purine-rich element binding protein B
chr7_-_47621741 0.184 NM_022748
TNS3
tensin 3
chr10_-_43903220 0.183 NM_001098206
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr4_-_78740508 0.180 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr3_-_125094003 0.180 NM_021964
ZNF148
zinc finger protein 148
chr16_-_10674443 0.176 NM_001424
EMP2
epithelial membrane protein 2
chr5_-_115910406 0.172 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_123095555 0.172 NM_001042750
NM_001042751
NM_006603
STAG2


stromal antigen 2


chr8_-_42698447 0.172 NM_018105
NM_199003
THAP1

THAP domain containing, apoptosis associated protein 1

chr19_+_2164119 0.171 NM_032482
DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr11_+_109964086 0.171 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr5_-_59064437 0.170 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_109065576 0.170 NM_181453
GCC2
GRIP and coiled-coil domain containing 2
chr11_+_11862955 0.169 NM_017944
USP47
ubiquitin specific peptidase 47
chr1_+_154193294 0.168 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr3_-_15900928 0.168 NM_015199
ANKRD28
ankyrin repeat domain 28
chr4_+_106067754 0.168 NM_001127208
TET2
tet methylcytosine dioxygenase 2
chr15_-_60919642 0.167 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr6_+_4021500 0.167 NM_003913
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr4_-_125633716 0.166 NM_001167882
NM_020337
ANKRD50

ankyrin repeat domain 50

chr11_-_34535302 0.165 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr20_-_52199635 0.163 NM_006526
ZNF217
zinc finger protein 217
chr15_+_77223942 0.163 NM_002902
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr8_-_82024277 0.162 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr8_-_124544376 0.161 NM_148177
FBXO32
F-box protein 32
chr4_-_36245893 0.160 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_+_9137560 0.159 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr6_-_166075520 0.158 NM_006661
NM_001130690
PDE10A

phosphodiesterase 10A

chr13_-_79233266 0.157 NM_024546
RNF219
ring finger protein 219

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 4.56e-08 GO:0050794 regulation of cellular process
1.64 6.26e-07 GO:0080090 regulation of primary metabolic process
1.65 9.87e-07 GO:0060255 regulation of macromolecule metabolic process
1.78 2.72e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.35 2.74e-06 GO:0050789 regulation of biological process
1.60 3.16e-06 GO:0031323 regulation of cellular metabolic process
2.34 4.36e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.75 5.69e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.72 1.43e-05 GO:0010468 regulation of gene expression
1.68 3.87e-05 GO:0031326 regulation of cellular biosynthetic process
1.66 7.05e-05 GO:0009889 regulation of biosynthetic process
1.72 1.09e-04 GO:0051252 regulation of RNA metabolic process
1.65 1.43e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 1.65e-04 GO:0019222 regulation of metabolic process
1.28 2.82e-04 GO:0065007 biological regulation
2.25 2.98e-04 GO:0009891 positive regulation of biosynthetic process
1.61 3.53e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.30 4.21e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
2.48 4.35e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.24 4.60e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.32 4.76e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.58 7.58e-04 GO:0045892 negative regulation of transcription, DNA-dependent
2.30 7.67e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.42 1.10e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.53 1.21e-03 GO:0051253 negative regulation of RNA metabolic process
2.37 1.32e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.34 1.39e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.43 1.44e-03 GO:0010629 negative regulation of gene expression
1.66 1.94e-03 GO:0006355 regulation of transcription, DNA-dependent
2.40 2.02e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32 2.24e-03 GO:0051254 positive regulation of RNA metabolic process
2.29 2.33e-03 GO:0009890 negative regulation of biosynthetic process
2.37 2.70e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.85 2.84e-03 GO:0016568 chromatin modification
2.30 2.84e-03 GO:0010628 positive regulation of gene expression
2.09 3.32e-03 GO:0031324 negative regulation of cellular metabolic process
2.24 5.25e-03 GO:0009790 embryo development
1.89 6.33e-03 GO:0031325 positive regulation of cellular metabolic process
1.85 8.00e-03 GO:0009893 positive regulation of metabolic process
1.53 9.43e-03 GO:0048518 positive regulation of biological process
2.02 1.01e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.49 1.07e-02 GO:0006325 chromatin organization
2.48 1.17e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.63 1.21e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.88 1.23e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.57 1.48e-02 GO:0048519 negative regulation of biological process
1.95 1.53e-02 GO:0009892 negative regulation of metabolic process
5.58 1.63e-02 GO:0060538 skeletal muscle organ development
1.55 1.82e-02 GO:0048522 positive regulation of cellular process
1.36 2.89e-02 GO:0044260 cellular macromolecule metabolic process
2.57 3.96e-02 GO:0009792 embryo development ending in birth or egg hatching
2.18 4.06e-02 GO:0051276 chromosome organization
1.57 4.17e-02 GO:0048523 negative regulation of cellular process
4.21 4.23e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
1.96 4.27e-02 GO:0006351 transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.52 9.16e-11 GO:0005634 nucleus
1.95 9.80e-08 GO:0031981 nuclear lumen
1.80 9.87e-07 GO:0044428 nuclear part
2.07 1.64e-06 GO:0005654 nucleoplasm
1.17 3.43e-05 GO:0005622 intracellular
1.68 5.39e-05 GO:0070013 intracellular organelle lumen
2.34 6.18e-05 GO:0044451 nucleoplasm part
1.67 7.13e-05 GO:0043233 organelle lumen
1.64 1.51e-04 GO:0031974 membrane-enclosed lumen
1.17 1.91e-04 GO:0044424 intracellular part
1.20 4.77e-03 GO:0043231 intracellular membrane-bounded organelle
1.20 5.28e-03 GO:0043227 membrane-bounded organelle
2.73 3.09e-02 GO:0005667 transcription factor complex
1.16 3.44e-02 GO:0043229 intracellular organelle
1.16 4.04e-02 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 4.54e-09 GO:0005488 binding
2.28 9.63e-07 GO:0030528 transcription regulator activity
1.58 5.24e-06 GO:0003676 nucleic acid binding
2.52 6.94e-06 GO:0043565 sequence-specific DNA binding
1.49 2.14e-05 GO:0046872 metal ion binding
1.48 2.95e-05 GO:0043167 ion binding
1.48 4.43e-05 GO:0043169 cation binding
5.73 4.72e-05 GO:0003704 specific RNA polymerase II transcription factor activity
1.30 5.93e-05 GO:0005515 protein binding
3.19 7.46e-05 GO:0016564 transcription repressor activity
3.44 9.82e-05 GO:0003702 RNA polymerase II transcription factor activity
1.64 1.77e-04 GO:0003677 DNA binding
2.02 5.17e-04 GO:0001071 nucleic acid binding transcription factor activity
2.02 5.17e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
3.58 1.09e-03 GO:0043566 structure-specific DNA binding
4.09 1.41e-03 GO:0003690 double-stranded DNA binding
1.61 2.38e-03 GO:0008270 zinc ion binding
6.54 8.52e-03 GO:0046332 SMAD binding
3.17 1.75e-02 GO:0003682 chromatin binding
1.50 1.87e-02 GO:0046914 transition metal ion binding
2.43 2.21e-02 GO:0003712 transcription cofactor activity
2.42 2.31e-02 GO:0000988 protein binding transcription factor activity
2.42 2.31e-02 GO:0000989 transcription factor binding transcription factor activity
2.29 3.03e-02 GO:0004674 protein serine/threonine kinase activity
2.26 3.54e-02 GO:0019904 protein domain specific binding
2.57 4.04e-02 GO:0008134 transcription factor binding