Motif ID: ACAGUAC

Z-value: 0.801


Mature miRNA associated with seed ACAGUAC:

NamemiRBase Accession
hsa-miR-101 MIMAT0000099



Activity profile for motif ACAGUAC.

activity profile for motif ACAGUAC


Sorted Z-values histogram for motif ACAGUAC

Sorted Z-values for motif ACAGUAC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_163149001 1.475 NM_001080379
 PACRG
PARK2 co-regulated
chr6_+_163148163 1.454 NM_001080378
NM_152410
 PACRG

PARK2 co-regulated

chr8_-_23712297 1.443 NM_003155
 STC1
stanniocalcin 1
chr3_+_3841079 1.333 NM_020873
 LRRN1
leucine rich repeat neuronal 1
chrY_+_15016018 1.318 NM_001122665
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_+_115803805 1.298 NM_000684
 ADRB1
adrenergic, beta-1-, receptor
chr7_-_148580600 0.891 NM_001203249
 EZH2
enhancer of zeste homolog 2 (Drosophila)
chrY_+_15016698 0.861 NM_004660
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr11_-_115375065 0.858 NM_001098517
NM_014333
 CADM1

cell adhesion molecule 1

chr1_-_186649421 0.818 NM_000963
 PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_148581403 0.815 NM_001203247
NM_001203248
NM_004456
NM_152998
 EZH2



enhancer of zeste homolog 2 (Drosophila)



chr1_-_204459445 0.806 NM_002646
 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr5_+_149151502 0.796 NM_001172699
 PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr6_+_151815174 0.791 NM_025059
 C6orf97
chromosome 6 open reading frame 97
chr5_+_149109814 0.745 NM_001172698
NM_133263
 PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr20_+_11898536 0.739 NM_014962
 BTBD3
BTB (POZ) domain containing 3
chr8_+_75896707 0.695 NM_031461
 CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr2_-_217560247 0.693 NM_000599
 IGFBP5
insulin-like growth factor binding protein 5
chr2_-_99771186 0.657 NM_025244
 TSGA10
testis specific, 10
chr2_-_99758034 0.642 NM_182911
 TSGA10
testis specific, 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 55 entries
enrichment   p-value GO term description
5.58 1.63e-02 GO:0060538 skeletal muscle organ development
4.21 4.23e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
2.85 2.84e-03 GO:0016568 chromatin modification
2.63 1.21e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.58 7.58e-04 GO:0045892 negative regulation of transcription, DNA-dependent
2.57 3.96e-02 GO:0009792 embryo development ending in birth or egg hatching
2.53 1.21e-03 GO:0051253 negative regulation of RNA metabolic process
2.49 1.07e-02 GO:0006325 chromatin organization
2.48 4.35e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.48 1.17e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.43 1.44e-03 GO:0010629 negative regulation of gene expression
2.42 1.10e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.40 2.02e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.37 1.32e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.37 2.70e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.34 4.36e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.34 1.39e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.32 4.76e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32 2.24e-03 GO:0051254 positive regulation of RNA metabolic process
2.30 4.21e-04 GO:0051173 positive regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.73 3.09e-02 GO:0005667 transcription factor complex
2.34 6.18e-05 GO:0044451 nucleoplasm part
2.07 1.64e-06 GO:0005654 nucleoplasm
1.95 9.80e-08 GO:0031981 nuclear lumen
1.80 9.87e-07 GO:0044428 nuclear part
1.68 5.39e-05 GO:0070013 intracellular organelle lumen
1.67 7.13e-05 GO:0043233 organelle lumen
1.64 1.51e-04 GO:0031974 membrane-enclosed lumen
1.52 9.16e-11 GO:0005634 nucleus
1.20 4.77e-03 GO:0043231 intracellular membrane-bounded organelle
1.20 5.28e-03 GO:0043227 membrane-bounded organelle
1.17 3.43e-05 GO:0005622 intracellular
1.17 1.91e-04 GO:0044424 intracellular part
1.16 3.44e-02 GO:0043229 intracellular organelle
1.16 4.04e-02 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
6.54 8.52e-03 GO:0046332 SMAD binding
5.73 4.72e-05 GO:0003704 specific RNA polymerase II transcription factor activity
4.09 1.41e-03 GO:0003690 double-stranded DNA binding
3.58 1.09e-03 GO:0043566 structure-specific DNA binding
3.44 9.82e-05 GO:0003702 RNA polymerase II transcription factor activity
3.19 7.46e-05 GO:0016564 transcription repressor activity
3.17 1.75e-02 GO:0003682 chromatin binding
2.57 4.04e-02 GO:0008134 transcription factor binding
2.52 6.94e-06 GO:0043565 sequence-specific DNA binding
2.43 2.21e-02 GO:0003712 transcription cofactor activity
2.42 2.31e-02 GO:0000988 protein binding transcription factor activity
2.42 2.31e-02 GO:0000989 transcription factor binding transcription factor activity
2.29 3.03e-02 GO:0004674 protein serine/threonine kinase activity
2.28 9.63e-07 GO:0030528 transcription regulator activity
2.26 3.54e-02 GO:0019904 protein domain specific binding
2.02 5.17e-04 GO:0001071 nucleic acid binding transcription factor activity
2.02 5.17e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.64 1.77e-04 GO:0003677 DNA binding
1.61 2.38e-03 GO:0008270 zinc ion binding
1.58 5.24e-06 GO:0003676 nucleic acid binding