Motif ID: ACAGUAU

Z-value: 0.885


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
hsa-miR-144 MIMAT0000436



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_131241321 2.940 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr15_-_48470453 1.840 NM_016132
MYEF2
myelin expression factor 2
chr2_-_99771186 1.477 NM_025244
TSGA10
testis specific, 10
chr2_-_99758034 1.462 NM_182911
TSGA10
testis specific, 10
chr8_+_136469557 1.317 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr22_+_29279573 1.286 NM_001206998
ZNRF3
zinc and ring finger 3
chr6_+_126111782 1.281 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr16_-_53737713 1.264 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr6_+_126240369 1.229 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr10_-_75335415 1.221 NM_152586
USP54
ubiquitin specific peptidase 54
chr3_+_3841079 1.219 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr6_+_107811272 1.214 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr8_+_75896707 1.204 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr6_+_19837599 1.203 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr6_+_17281773 1.188 NM_001143942
RBM24
RNA binding motif protein 24
chr6_+_17282931 1.165 NM_153020
RBM24
RNA binding motif protein 24
chr6_+_17282294 1.162 NM_001143941
RBM24
RNA binding motif protein 24
chr1_+_183605207 1.155 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_244214552 1.155 NM_205768
ZNF238
zinc finger protein 238
chr17_-_63557615 1.137 NM_004655
AXIN2
axin 2
chr19_-_33555757 1.128 NM_033103
RHPN2
rhophilin, Rho GTPase binding protein 2
chr19_+_10543110 1.059 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr5_-_38595506 1.031 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_244216506 1.021 NM_006352
ZNF238
zinc finger protein 238
chr22_+_29313376 1.010 NM_032173
ZNRF3
zinc and ring finger 3
chr5_+_127419407 0.993 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr4_+_72052354 0.972 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr5_-_115910406 0.969 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_135502445 0.969 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr5_-_38556682 0.922 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr6_+_126102278 0.914 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr20_+_37434294 0.913 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr15_-_93632161 0.906 NM_020211
RGMA
RGM domain family, member A
chr15_-_93616891 0.898 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr19_+_10563581 0.880 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_+_6784453 0.876 NM_001100590
NM_014743
KIAA0232

KIAA0232

chr15_-_93617091 0.874 NM_001166283
RGMA
RGM domain family, member A
chr6_-_10838712 0.870 NM_001242385
NM_001242957
NM_005906
MAK


male germ cell-associated kinase


chr10_+_115803805 0.842 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr20_+_51588945 0.838 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr16_+_14164879 0.833 NM_014048
MKL2
MKL/myocardin-like 2
chr15_-_93631751 0.830 NM_001166287
RGMA
RGM domain family, member A
chr20_+_51801821 0.827 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr5_+_149109814 0.815 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr1_-_217262946 0.814 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr21_-_43373938 0.813 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr5_+_149151502 0.809 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr15_-_93616358 0.802 NM_001166286
RGMA
RGM domain family, member A
chr19_+_10541334 0.789 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_33722158 0.772 NM_152493
ZNF362
zinc finger protein 362
chr19_+_10531128 0.762 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_+_95679075 0.761 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_61547625 0.756 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_-_217311095 0.750 NM_001134285
ESRRG
estrogen-related receptor gamma
chrX_+_51486479 0.747 NM_018094
GSPT2
G1 to S phase transition 2
chr1_+_61542928 0.731 NM_001145511
NFIA
nuclear factor I/A
chr1_-_173962050 0.729 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr1_-_216896640 0.727 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr15_-_75743776 0.717 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr15_-_75744029 0.705 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr6_+_36164528 0.695 NM_015695
BRPF3
bromodomain and PHD finger containing, 3
chr15_-_75748123 0.694 NM_001145357
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr6_+_122720685 0.684 NM_001135564
NM_001243094
NM_004506
HSF2


heat shock transcription factor 2


chr9_-_99329092 0.678 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr16_+_67927170 0.662 NM_006742
PSKH1
protein serine kinase H1
chr8_+_17354562 0.652 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_+_72204769 0.646 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_+_64936475 0.646 NM_020925
CACHD1
cache domain containing 1
chr4_+_41614911 0.634 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr12_+_46123495 0.633 NM_152641
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr7_-_120498128 0.629 NM_012338
TSPAN12
tetraspanin 12
chr12_-_56652118 0.610 NM_173595
ANKRD52
ankyrin repeat domain 52
chr14_-_61190458 0.609 NM_017420
SIX4
SIX homeobox 4
chr1_+_61547388 0.607 NM_001145512
NFIA
nuclear factor I/A
chr11_-_95522945 0.606 NM_144664
FAM76B
family with sequence similarity 76, member B
chr16_-_12010518 0.604 NM_001130007
GSPT1
G1 to S phase transition 1
chr7_-_139876718 0.597 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr10_-_94050799 0.591 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_+_56414688 0.591 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr13_-_37494370 0.570 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr2_-_217560247 0.569 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr11_-_34535302 0.559 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr4_+_41362750 0.558 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr4_+_106067754 0.557 NM_001127208
TET2
tet methylcytosine dioxygenase 2
chr2_-_188312872 0.555 NM_005795
CALCRL
calcitonin receptor-like
chr15_-_37392358 0.540 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr9_+_126773851 0.534 NM_004789
LHX2
LIM homeobox 2
chr9_-_125590809 0.533 NM_005388
PDCL
phosducin-like
chr7_-_149157866 0.531 NM_015694
ZNF777
zinc finger protein 777
chr11_-_34533117 0.530 NM_001243081
NM_198381
ELF5

E74-like factor 5 (ets domain transcription factor)

chr15_-_37391596 0.529 NM_172316
MEIS2
Meis homeobox 2
chr15_-_37390372 0.526 NM_172315
MEIS2
Meis homeobox 2
chr8_+_17396285 0.525 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr12_-_109747024 0.524 NM_213596
FOXN4
forkhead box N4
chr3_-_15900928 0.513 NM_015199
ANKRD28
ankyrin repeat domain 28
chr13_-_41240607 0.512 NM_002015
FOXO1
forkhead box O1
chr3_-_101231973 0.508 NM_001077203
NM_020654
SENP7

SUMO1/sentrin specific peptidase 7

chr11_-_8832881 0.507 NM_139157
ST5
suppression of tumorigenicity 5
chr11_-_8832189 0.503 NM_213618
ST5
suppression of tumorigenicity 5
chr14_+_45431333 0.501 NM_015091
FAM179B
family with sequence similarity 179, member B
chr18_+_9137560 0.496 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr2_+_191273012 0.487 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr3_+_150321065 0.486 NM_016275
SELT
selenoprotein T
chr18_+_48556483 0.482 NM_005359
SMAD4
SMAD family member 4
chr2_-_160472960 0.471 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr11_-_8932497 0.465 NM_005418
ST5
suppression of tumorigenicity 5
chr16_+_50186809 0.462 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr5_+_142150291 0.461 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr20_-_4982133 0.461 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr17_-_58603492 0.460 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr21_-_43430448 0.460 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr15_-_37393364 0.458 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr3_-_15839674 0.456 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr1_-_174992552 0.456 NM_022100
MRPS14
mitochondrial ribosomal protein S14
chr20_-_61492945 0.456 NM_006602
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr10_-_94003002 0.451 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr9_-_99382073 0.450 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr7_+_8008416 0.449 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr21_-_36421586 0.449 NM_001754
RUNX1
runt-related transcription factor 1
chr3_-_136471186 0.447 NM_005862
STAG1
stromal antigen 1
chr7_-_44887697 0.442 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr18_-_53255734 0.441 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr10_+_76586299 0.436 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr16_-_87525317 0.432 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr10_+_120789227 0.431 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr5_+_153825497 0.423 NM_001131062
NM_001131063
NM_024632
SAP30L


SAP30-like


chr5_-_176981537 0.413 NM_001190946
FAM193B
family with sequence similarity 193, member B
chr17_+_7608413 0.411 NM_001406
EFNB3
ephrin-B3
chr4_+_106816593 0.410 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr16_-_68482373 0.406 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr6_+_143929316 0.406 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr6_-_134496006 0.405 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_+_143999058 0.404 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_-_245027808 0.403 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr6_-_134497069 0.399 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_69812961 0.399 NM_006722
MITF
microphthalmia-associated transcription factor
chr15_-_61521478 0.397 NM_134261
RORA
RAR-related orphan receptor A
chr8_+_79578258 0.394 NM_016010
FAM164A
family with sequence similarity 164, member A
chr12_-_68726036 0.388 NM_001205028
NM_001205029
NM_017440
NM_020128
MDM1



Mdm1 nuclear protein homolog (mouse)



chr15_-_60884615 0.380 NM_134262
RORA
RAR-related orphan receptor A
chr21_-_43346780 0.374 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr7_+_73442426 0.371 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr6_-_90121966 0.370 NM_021244
RRAGD
Ras-related GTP binding D
chr5_-_59783885 0.370 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_107435635 0.369 NM_001080450
BEND3
BEN domain containing 3
chr15_+_96869156 0.367 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_+_23986735 0.361 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr4_-_141075232 0.356 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr14_+_73525187 0.356 NM_021239
RBM25
RNA binding motif protein 25
chr3_+_23987514 0.352 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr15_+_96876568 0.349 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_-_169455099 0.345 NM_006996
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr6_-_134639195 0.344 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr16_-_12009804 0.344 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr8_-_124553448 0.340 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr10_-_61900659 0.337 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_-_134498973 0.337 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_134181369 0.336 NM_152409
C5orf24
chromosome 5 open reading frame 24
chr1_-_47779651 0.335 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr19_-_47735858 0.331 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr15_-_77363519 0.327 NM_001168412
NM_005724
NM_198902
TSPAN3


tetraspanin 3


chr3_+_69915374 0.325 NM_198177
MITF
microphthalmia-associated transcription factor
chr8_-_42698447 0.325 NM_018105
NM_199003
THAP1

THAP domain containing, apoptosis associated protein 1

chr10_-_62149487 0.324 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_108976509 0.321 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr8_+_61429390 0.321 NM_001242644
NM_002865
RAB2A

RAB2A, member RAS oncogene family

chr15_-_60919642 0.318 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr3_+_69812620 0.314 NM_001184967
MITF
microphthalmia-associated transcription factor
chr6_-_139695349 0.313 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr19_-_47734215 0.313 NM_014417
BBC3
BCL2 binding component 3
chr10_-_13390189 0.310 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr21_+_44394634 0.309 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr7_-_47621741 0.309 NM_022748
TNS3
tensin 3
chr18_+_9136742 0.306 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr6_+_33387846 0.306 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr3_+_69788562 0.305 NM_198159
MITF
microphthalmia-associated transcription factor
chr15_+_100106132 0.305 NM_001130926
NM_001130927
NM_001171894
NM_005587
MEF2A



myocyte enhancer factor 2A



chr9_-_98270321 0.304 NM_001083604
NM_001083605
PTCH1

patched 1

chr6_-_139695784 0.300 NM_006079
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_235490801 0.300 NM_001206794
ARID4B
AT rich interactive domain 4B (RBP1-like)
chr4_+_144434555 0.299 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr1_+_26798901 0.294 NM_005517
HMGN2
high mobility group nucleosomal binding domain 2
chr11_+_109964086 0.293 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr11_-_70507911 0.291 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_+_179923870 0.290 NM_014810
CEP350
centrosomal protein 350kDa
chr12_-_102224509 0.290 NM_024312
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr10_-_62332666 0.289 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_+_68042493 0.286 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr6_+_148663728 0.283 NM_015278
SASH1
SAM and SH3 domain containing 1
chr10_-_98346793 0.282 NM_020123
TM9SF3
transmembrane 9 superfamily member 3
chr6_-_52926588 0.276 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr3_+_88188261 0.276 NM_018293
ZNF654
zinc finger protein 654
chr14_+_103800492 0.276 NM_001969
EIF5
eukaryotic translation initiation factor 5
chr19_-_33793429 0.274 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr9_-_98269686 0.274 NM_001083606
PTCH1
patched 1
chr1_+_204485461 0.274 NM_001204171
NM_001204172
NM_002393
MDM4


Mdm4 p53 binding protein homolog (mouse)


chr15_+_96875793 0.272 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_24149899 0.271 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr10_-_62493282 0.271 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr20_-_4990913 0.269 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.06 7.05e-13 GO:0010468 regulation of gene expression
2.04 1.75e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.02 1.92e-11 GO:0010556 regulation of macromolecule biosynthetic process
1.76 3.99e-10 GO:0080090 regulation of primary metabolic process
1.78 6.51e-10 GO:0060255 regulation of macromolecule metabolic process
1.74 1.23e-09 GO:0031323 regulation of cellular metabolic process
1.89 1.41e-09 GO:0009889 regulation of biosynthetic process
1.89 1.48e-09 GO:0031326 regulation of cellular biosynthetic process
1.97 3.61e-09 GO:0051252 regulation of RNA metabolic process
1.66 8.81e-09 GO:0019222 regulation of metabolic process
1.83 3.75e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 1.08e-07 GO:0050794 regulation of cellular process
1.78 2.54e-07 GO:0051171 regulation of nitrogen compound metabolic process
2.47 2.84e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.86 1.40e-06 GO:0006355 regulation of transcription, DNA-dependent
1.35 3.13e-06 GO:0050789 regulation of biological process
2.68 3.73e-05 GO:0010629 negative regulation of gene expression
2.78 5.23e-05 GO:0045892 negative regulation of transcription, DNA-dependent
2.45 6.34e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
2.73 8.75e-05 GO:0051253 negative regulation of RNA metabolic process
2.59 9.31e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.54 1.07e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.58 1.63e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.29 1.71e-04 GO:0009891 positive regulation of biosynthetic process
1.29 1.76e-04 GO:0065007 biological regulation
3.47 1.96e-04 GO:0010608 posttranscriptional regulation of gene expression
2.45 2.03e-04 GO:0009890 negative regulation of biosynthetic process
2.54 2.24e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
2.53 2.46e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.28 2.67e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.44 3.20e-04 GO:0031327 negative regulation of cellular biosynthetic process
4.27 3.53e-04 GO:0006417 regulation of translation
2.42 5.27e-04 GO:0051254 positive regulation of RNA metabolic process
2.40 6.77e-04 GO:0010628 positive regulation of gene expression
2.18 9.29e-04 GO:0006351 transcription, DNA-dependent
2.07 1.81e-03 GO:0009892 negative regulation of metabolic process
2.25 1.88e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.78 2.80e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.41 3.75e-03 GO:0044260 cellular macromolecule metabolic process
2.18 4.02e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.08 4.65e-03 GO:0031324 negative regulation of cellular metabolic process
2.05 6.19e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.91 7.11e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.72 7.33e-03 GO:0016070 RNA metabolic process
1.89 7.63e-03 GO:0031325 positive regulation of cellular metabolic process
2.52 8.07e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.85 9.36e-03 GO:0009893 positive regulation of metabolic process
1.68 9.93e-03 GO:0010467 gene expression
1.45 1.26e-02 GO:0007275 multicellular organismal development
1.97 1.47e-02 GO:0032774 RNA biosynthetic process
1.56 1.49e-02 GO:0048522 positive regulation of cellular process
1.41 2.43e-02 GO:0032502 developmental process
1.57 2.89e-02 GO:0090304 nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.55 8.98e-12 GO:0005634 nucleus
1.18 1.11e-05 GO:0005622 intracellular
1.92 1.01e-04 GO:0005654 nucleoplasm
1.75 1.52e-04 GO:0031981 nuclear lumen
1.17 2.15e-04 GO:0044424 intracellular part
1.23 4.15e-04 GO:0043231 intracellular membrane-bounded organelle
1.23 4.63e-04 GO:0043227 membrane-bounded organelle
2.21 5.84e-04 GO:0044451 nucleoplasm part
1.63 6.52e-04 GO:0044428 nuclear part
1.53 9.06e-03 GO:0070013 intracellular organelle lumen
1.52 1.09e-02 GO:0043233 organelle lumen
1.50 1.95e-02 GO:0031974 membrane-enclosed lumen
1.16 3.47e-02 GO:0043229 intracellular organelle
1.16 4.06e-02 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.89 2.95e-14 GO:0003676 nucleic acid binding
2.56 9.28e-10 GO:0030528 transcription regulator activity
2.54 2.81e-09 GO:0001071 nucleic acid binding transcription factor activity
2.54 2.81e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.88 1.17e-08 GO:0003677 DNA binding
1.20 4.11e-08 GO:0005488 binding
2.80 4.40e-08 GO:0043565 sequence-specific DNA binding
3.50 3.34e-06 GO:0016564 transcription repressor activity
1.76 2.12e-05 GO:0008270 zinc ion binding
2.99 5.86e-05 GO:0003712 transcription cofactor activity
2.98 6.21e-05 GO:0000988 protein binding transcription factor activity
2.98 6.21e-05 GO:0000989 transcription factor binding transcription factor activity
1.46 1.74e-04 GO:0046872 metal ion binding
1.44 3.38e-04 GO:0043169 cation binding
1.44 3.90e-04 GO:0043167 ion binding
3.20 9.93e-04 GO:0003702 RNA polymerase II transcription factor activity
1.58 1.67e-03 GO:0046914 transition metal ion binding
3.11 7.35e-03 GO:0003713 transcription coactivator activity
4.58 8.83e-03 GO:0003704 specific RNA polymerase II transcription factor activity
1.97 9.60e-03 GO:0003723 RNA binding
2.68 9.86e-03 GO:0016563 transcription activator activity
1.22 3.11e-02 GO:0005515 protein binding