Motif ID: AGCACCA

Z-value: 0.919


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a MIMAT0000086
hsa-miR-29b MIMAT0000100
hsa-miR-29c MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_23261675 2.917 NM_002318
 LOXL2
lysyl oxidase-like 2
chr2_-_1748285 2.663 NM_012293
 PXDN
peroxidasin homolog (Drosophila)
chr13_+_110959592 2.522 NM_001846
 COL4A2
collagen, type IV, alpha 2
chr5_-_151066492 2.515 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_-_17307107 2.502 NM_001135248
NM_002403
 MFAP2

microfibrillar-associated protein 2

chr1_-_17308072 2.343 NM_001135247
NM_017459
 MFAP2

microfibrillar-associated protein 2

chr1_+_151032150 2.263 NM_006818
 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_+_69139466 2.204 NM_001199280
 HAS3
hyaluronan synthase 3
chr1_-_113498828 2.194 NM_003051
 SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr15_+_81071708 2.178 NM_018689
 KIAA1199
KIAA1199
chr16_+_55515468 2.163 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_-_113498615 2.108 NM_001166496
 SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr16_+_69141442 2.097 NM_005329
 HAS3
hyaluronan synthase 3
chr8_+_86376130 2.088 NM_000067
 CA2
carbonic anhydrase II
chr12_+_13349601 2.067 NM_001423
 EMP1
epithelial membrane protein 1
chr2_-_190044330 2.051 NM_000393
 COL5A2
collagen, type V, alpha 2
chr3_-_48632592 2.015 NM_000094
 COL7A1
collagen, type VII, alpha 1
chr5_-_139726173 1.991 NM_001945
 HBEGF
heparin-binding EGF-like growth factor
chrX_-_107681555 1.924 NM_033641
 COL4A6
collagen, type IV, alpha 6
chrX_-_107682600 1.821 NM_001847
 COL4A6
collagen, type IV, alpha 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
28.62 2.85e-03 GO:0032964 collagen biosynthetic process
8.71 1.81e-02 GO:0046326 positive regulation of glucose import
8.02 3.34e-02 GO:0010828 positive regulation of glucose transport
7.71 4.43e-02 GO:0010676 positive regulation of cellular carbohydrate metabolic process
7.71 4.43e-02 GO:0045913 positive regulation of carbohydrate metabolic process
3.96 4.55e-02 GO:0030198 extracellular matrix organization
2.61 7.86e-03 GO:0007411 axon guidance
2.31 3.08e-02 GO:0007409 axonogenesis
2.26 2.19e-03 GO:0048666 neuron development
2.26 3.46e-02 GO:0048812 neuron projection morphogenesis
2.17 4.19e-02 GO:0031175 neuron projection development
2.14 5.26e-03 GO:0030030 cell projection organization
2.07 4.35e-04 GO:0048699 generation of neurons
2.06 2.55e-04 GO:0022008 neurogenesis
1.99 1.34e-02 GO:2000026 regulation of multicellular organismal development
1.96 4.47e-02 GO:0030182 neuron differentiation
1.92 6.11e-03 GO:0050793 regulation of developmental process
1.92 1.14e-02 GO:0040011 locomotion
1.90 7.17e-06 GO:0007399 nervous system development
1.90 7.86e-03 GO:0048468 cell development

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
28.62 1.27e-02 GO:0005588 collagen type V
23.85 9.04e-05 GO:0005587 collagen type IV
20.45 3.07e-04 GO:0030935 sheet-forming collagen
15.61 2.15e-04 GO:0005583 fibrillar collagen
11.93 1.06e-10 GO:0005581 collagen
5.83 2.06e-09 GO:0044420 extracellular matrix part
5.73 3.46e-05 GO:0005604 basement membrane
4.77 3.62e-04 GO:0030027 lamellipodium
3.20 1.49e-03 GO:0031252 cell leading edge
3.18 8.88e-07 GO:0005578 proteinaceous extracellular matrix
2.70 5.40e-05 GO:0031012 extracellular matrix
1.75 2.91e-02 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
15.61 2.75e-04 GO:0048407 platelet-derived growth factor binding
9.54 4.45e-02 GO:0005161 platelet-derived growth factor receptor binding
5.37 3.88e-05 GO:0005201 extracellular matrix structural constituent
3.85 1.56e-03 GO:0030674 protein binding, bridging
3.83 8.34e-04 GO:0060090 binding, bridging
1.33 2.49e-08 GO:0005515 protein binding
1.13 6.77e-04 GO:0005488 binding