Motif ID: AGCAGCG

Z-value: 0.644


Mature miRNA associated with seed AGCAGCG:

NamemiRBase Accession
hsa-miR-503 MIMAT0002874



Activity profile for motif AGCAGCG.

activity profile for motif AGCAGCG


Sorted Z-values histogram for motif AGCAGCG

Sorted Z-values for motif AGCAGCG



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_22469414 2.856 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr6_-_24911194 2.689 NM_014722
FAM65B
family with sequence similarity 65, member B
chr4_+_72052354 2.664 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr1_-_159869897 2.449 NM_012337
CCDC19
coiled-coil domain containing 19
chr4_+_75858205 2.446 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr6_+_135502445 2.420 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr17_+_68165660 2.416 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr5_+_140254930 2.278 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr5_+_140186658 2.275 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr5_+_140213968 2.254 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr5_+_140220811 2.212 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr12_-_63328663 2.136 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_14316980 1.965 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr11_+_111848008 1.954 NM_033425
DIXDC1
DIX domain containing 1
chr16_+_58549382 1.952 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr5_+_140247767 1.856 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr20_-_39317875 1.829 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr17_+_7761063 1.606 NM_144607
CYB5D1
cytochrome b5 domain containing 1
chr4_+_72204769 1.566 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr5_+_140165875 1.465 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr5_+_140207562 1.423 NM_018909
NM_031848
NM_031849
PCDHA6


protocadherin alpha 6


chr6_-_134496006 1.385 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134497069 1.359 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_149632772 1.358 NM_004522
KIF5C
kinesin family member 5C
chr8_+_17354562 1.352 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr7_+_114055048 1.349 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr20_-_62436855 1.344 NM_025224
ZBTB46
zinc finger and BTB domain containing 46
chr12_-_39836760 1.310 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chr11_+_111807857 1.240 NM_001037954
DIXDC1
DIX domain containing 1
chr6_-_134639195 1.213 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_140345746 1.212 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr6_-_134498973 1.206 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chrX_-_8700170 1.113 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr5_+_127419407 1.108 NM_001046
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr18_-_30050394 1.102 NM_001242409
NM_022751
FAM59A

family with sequence similarity 59, member A

chr11_-_119234859 1.102 NM_171997
USP2
ubiquitin specific peptidase 2
chr13_-_36705513 1.094 NM_004734
DCLK1
doublecortin-like kinase 1
chr8_+_17396285 1.090 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr5_+_140180782 1.084 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr19_-_7293876 1.060 NM_000208
NM_001079817
INSR

insulin receptor

chr1_-_36915969 1.048 NM_145047
NM_206837
OSCP1

organic solute carrier partner 1

chr13_-_36429798 0.997 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_+_140261792 0.965 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr5_+_140235594 0.919 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr5_+_42423811 0.904 NM_000163
GHR
growth hormone receptor
chr11_-_110583120 0.903 NM_020809
ARHGAP20
Rho GTPase activating protein 20
chr6_+_163149001 0.899 NM_001080379
PACRG
PARK2 co-regulated
chr6_+_163148163 0.890 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr5_+_42424553 0.878 NM_001242399
NM_001242400
GHR

growth hormone receptor

chr5_+_42425093 0.852 NM_001242401
GHR
growth hormone receptor
chr5_+_42548144 0.842 NM_001242402
GHR
growth hormone receptor
chr5_+_42548314 0.825 NM_001242403
GHR
growth hormone receptor
chr5_+_42565963 0.822 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr6_-_80247103 0.809 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr5_+_42550181 0.808 NM_001242405
GHR
growth hormone receptor
chr11_-_8615412 0.806 NM_030906
STK33
serine/threonine kinase 33
chr5_+_42565562 0.801 NM_001242406
GHR
growth hormone receptor
chr16_+_67927170 0.780 NM_006742
PSKH1
protein serine kinase H1
chr1_+_33722158 0.780 NM_152493
ZNF362
zinc finger protein 362
chr5_+_42549657 0.767 NM_001242404
GHR
growth hormone receptor
chr6_+_143999058 0.761 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr6_+_143929316 0.746 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr14_-_39901619 0.742 NM_203301
FBXO33
F-box protein 33
chr20_-_1165116 0.738 NM_018354
TMEM74B
transmembrane protein 74B
chr11_-_119252364 0.722 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr5_+_67511578 0.712 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr13_+_100258886 0.707 NM_206808
CLYBL
citrate lyase beta like
chr18_+_29672568 0.703 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr10_+_88516340 0.664 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr12_+_12764755 0.638 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr5_-_54830369 0.636 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr5_+_102201526 0.632 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr5_+_67584251 0.604 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_179923870 0.599 NM_014810
CEP350
centrosomal protein 350kDa
chr10_-_21463019 0.588 NM_001173484
NM_213569
NEBL

nebulette

chr1_+_162467594 0.581 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr6_+_107811272 0.572 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr15_+_101459459 0.570 NM_024652
LRRK1
leucine-rich repeat kinase 1
chr4_+_184826427 0.567 NM_020225
STOX2
storkhead box 2
chr9_-_127703294 0.567 NM_002077
GOLGA1
golgin A1
chr1_+_162466963 0.564 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr16_-_20753117 0.558 NM_017736
THUMPD1
THUMP domain containing 1
chr18_+_67956136 0.555 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr5_+_139493689 0.555 NM_005859
PURA
purine-rich element binding protein A
chr11_-_130184459 0.553 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr15_+_69452799 0.548 NM_015554
GLCE
glucuronic acid epimerase
chr6_+_80340971 0.539 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr5_+_67586466 0.528 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr9_-_112260529 0.526 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_227127937 0.523 NM_020247
ADCK3
aarF domain containing kinase 3
chr17_-_27621163 0.505 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr16_-_30798206 0.500 NM_001080417
ZNF629
zinc finger protein 629
chr18_-_61034350 0.483 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr11_-_60928878 0.473 NM_017966
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr16_+_639668 0.470 NM_001172664
RAB40C
RAB40C, member RAS oncogene family
chr22_+_29279573 0.470 NM_001206998
ZNRF3
zinc and ring finger 3
chr11_-_74109417 0.466 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr15_-_66084544 0.466 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr6_-_165723074 0.465 NM_144980
C6orf118
chromosome 6 open reading frame 118
chr10_-_94050799 0.460 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr16_+_640056 0.458 NM_001172665
NM_001172666
RAB40C

RAB40C, member RAS oncogene family

chr14_-_31676680 0.455 NM_015382
HECTD1
HECT domain containing 1
chr2_-_99279935 0.453 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr12_+_8234796 0.452 NM_015509
NECAP1
NECAP endocytosis associated 1
chr10_-_116418056 0.451 NM_002313
ABLIM1
actin binding LIM protein 1
chr16_+_640172 0.444 NM_021168
RAB40C
RAB40C, member RAS oncogene family
chr8_-_72268720 0.443 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr10_-_116444374 0.442 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr8_-_12051533 0.440 NM_001083537
FAM86B2
FAM86B1
family with sequence similarity 86, member B2
family with sequence similarity 86, member B1
chr1_-_155532322 0.438 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr3_+_42201658 0.436 NM_014965
TRAK1
trafficking protein, kinesin binding 1
chr2_+_97481977 0.435 NM_017623
NM_199078
CNNM3

cyclin M3

chr7_+_66386129 0.429 NM_017994
C7orf42
chromosome 7 open reading frame 42
chr17_+_61627818 0.421 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr10_-_116286661 0.417 NM_006720
ABLIM1
actin binding LIM protein 1
chr14_-_67982020 0.415 NM_182526
TMEM229B
transmembrane protein 229B
chr10_-_21186530 0.413 NM_006393
NEBL
nebulette
chr5_+_67588395 0.413 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr20_-_31071187 0.409 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr20_+_19193282 0.398 NM_020689
SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr12_-_110505499 0.398 NM_207435
C12orf76
chromosome 12 open reading frame 76
chr15_-_93632161 0.398 NM_020211
RGMA
RGM domain family, member A
chrX_-_108976509 0.397 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr9_+_4679557 0.397 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr16_+_639356 0.396 NM_001172663
RAB40C
RAB40C, member RAS oncogene family
chr17_+_65821625 0.394 NM_004459
NM_182641
BPTF

bromodomain PHD finger transcription factor

chr15_-_93616891 0.392 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr1_-_160232286 0.391 NM_015726
DCAF8
DDB1 and CUL4 associated factor 8
chr15_-_93617091 0.375 NM_001166283
RGMA
RGM domain family, member A
chr18_+_29671817 0.372 NM_016271
RNF138
ring finger protein 138
chr4_+_160188997 0.372 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr13_+_97874540 0.369 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr13_-_67804432 0.366 NM_020403
NM_203487
PCDH9

protocadherin 9

chr15_-_93616358 0.363 NM_001166286
RGMA
RGM domain family, member A
chr12_+_10365415 0.359 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr15_-_93631751 0.354 NM_001166287
RGMA
RGM domain family, member A
chr19_-_47734215 0.353 NM_014417
BBC3
BCL2 binding component 3
chr12_-_117628112 0.353 NM_015002
NM_033624
FBXO21

F-box protein 21

chr1_+_110036657 0.353 NM_001134402
NM_001134400
NM_001134403
NM_001134404
NM_182580
CYB561D1




cytochrome b-561 domain containing 1




chrX_+_10124984 0.351 NM_001830
CLCN4
chloride channel 4
chr3_+_187930720 0.349 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_47249302 0.342 NM_001039885
NM_024301
FKRP

fukutin related protein

chr5_+_140306301 0.340 NM_018898
NM_031882
PCDHAC1

protocadherin alpha subfamily C, 1

chr11_-_72852957 0.337 NM_014824
FCHSD2
FCH and double SH3 domains 2
chr11_+_71498497 0.336 NM_001099653
NM_018172
NM_152563
FAM86C1


family with sequence similarity 86, member C1


chr10_-_94003002 0.335 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_+_140774031 0.330 NM_001195278
LOC100507421
transmembrane protein 178-like
chr5_+_172483285 0.325 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chrY_+_15016018 0.324 NM_001122665
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_-_25864430 0.322 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_-_72274466 0.321 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr12_-_112819755 0.319 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr15_+_99192696 0.319 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr9_+_82186846 0.316 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_72921280 0.315 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr9_-_112213663 0.307 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_147013181 0.307 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr19_-_47735858 0.304 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr17_+_46125675 0.304 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr22_+_29313376 0.300 NM_032173
ZNRF3
zinc and ring finger 3
chr11_+_118307072 0.292 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr11_+_66234293 0.291 NM_001098510
NM_001243136
NM_145065
PELI3


pellino homolog 3 (Drosophila)


chr4_-_146100793 0.291 NM_001102653
OTUD4
OTU domain containing 4
chr2_+_198381021 0.290 NM_001204094
MOB4
MOB family member 4, phocein
chr2_+_152266384 0.289 NM_001177663
NM_018151
NM_001177664
RIF1


RAP1 interacting factor homolog (yeast)


chr19_+_41305333 0.281 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr1_+_24286300 0.279 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr19_+_41305041 0.275 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr1_+_203764750 0.274 NM_014827
ZC3H11A
zinc finger CCCH-type containing 11A
chr12_-_57400199 0.274 NM_014830
ZBTB39
zinc finger and BTB domain containing 39
chr12_-_56881901 0.271 NM_013267
GLS2
glutaminase 2 (liver, mitochondrial)
chr12_-_96794207 0.269 NM_001170464
NM_002595
CDK17

cyclin-dependent kinase 17

chr3_+_187871473 0.269 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_183387501 0.269 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr9_-_112191105 0.268 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr10_+_104678001 0.268 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr11_-_126138824 0.264 NM_001177842
NM_003139
SRPR

signal recognition particle receptor (docking protein)

chr9_-_127905715 0.260 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr8_+_37594078 0.258 NM_001003791
NM_007175
ERLIN2

ER lipid raft associated 2

chr13_+_20532906 0.256 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr1_+_167298280 0.253 NM_001198783
POU2F1
POU class 2 homeobox 1
chr22_+_40440664 0.253 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr11_-_129062092 0.251 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr17_-_65241305 0.251 NM_014877
HELZ
helicase with zinc finger
chr2_+_148602569 0.250 NM_001616
ACVR2A
activin A receptor, type IIA
chrY_+_15016698 0.249 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr17_+_58677489 0.245 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr2_+_198380294 0.245 NM_199482
MOB4
MOB family member 4, phocein
chr7_+_100026412 0.244 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr20_+_49348050 0.240 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr4_+_95679075 0.239 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_46669005 0.226 NM_001013615
C1orf190
chromosome 1 open reading frame 190
chr16_+_475629 0.224 NM_014700
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr15_+_74466887 0.221 NM_201526
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr1_+_167189948 0.220 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr2_+_198380752 0.218 NM_001100819
NM_015387
MOB4

MOB family member 4, phocein

chr16_+_524843 0.215 NM_001142272
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr10_-_61666236 0.213 NM_005436
CCDC6
coiled-coil domain containing 6
chr7_+_100027253 0.210 NM_019606
MEPCE
methylphosphate capping enzyme
chr8_+_67687415 0.207 NM_013257
NM_170709
SGK3

serum/glucocorticoid regulated kinase family, member 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
7.34 6.04e-07 GO:0007156 homophilic cell adhesion
2.08 7.63e-05 GO:0006464 protein modification process
2.51 1.76e-04 GO:0006793 phosphorus metabolic process
2.51 1.76e-04 GO:0006796 phosphate metabolic process
2.18 2.63e-04 GO:0007399 nervous system development
1.98 4.46e-04 GO:0043412 macromolecule modification
1.70 2.88e-03 GO:0048731 system development
3.67 4.92e-03 GO:0016337 cell-cell adhesion
2.67 6.38e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.39 1.06e-02 GO:0016310 phosphorylation
1.58 1.18e-02 GO:0007275 multicellular organismal development
1.69 1.89e-02 GO:0044267 cellular protein metabolic process
1.59 1.90e-02 GO:0048856 anatomical structure development
2.44 2.13e-02 GO:0006468 protein phosphorylation
13.66 2.68e-02 GO:0030501 positive regulation of bone mineralization
20.04 3.47e-02 GO:0048009 insulin-like growth factor receptor signaling pathway
12.52 4.20e-02 GO:0070169 positive regulation of biomineral tissue development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 3.49e-04 GO:0005488 binding
6.68 1.98e-03 GO:0019199 transmembrane receptor protein kinase activity
2.59 3.78e-03 GO:0004672 protein kinase activity
45.08 4.46e-03 GO:0043559 insulin binding
2.87 6.52e-03 GO:0004674 protein serine/threonine kinase activity
2.35 9.39e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.17 1.12e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.27 1.24e-02 GO:0016301 kinase activity
14.14 3.74e-02 GO:0005024 transforming growth factor beta receptor activity
1.27 3.81e-02 GO:0005515 protein binding
1.69 4.95e-02 GO:0035639 purine ribonucleoside triphosphate binding