Motif ID: AGUGCAA

Z-value: 0.466


Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
hsa-miR-130a MIMAT0000425
hsa-miR-130b MIMAT0000691
hsa-miR-301a MIMAT0000688
hsa-miR-301b MIMAT0004958
hsa-miR-3666 MIMAT0018088
hsa-miR-4295 MIMAT0016844
hsa-miR-454 MIMAT0003885



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_34419957 0.871 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr8_+_26371461 0.730 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr8_+_26435339 0.654 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr8_+_75896707 0.565 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr6_+_135502445 0.527 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr11_-_46939908 0.483 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr2_-_101767714 0.424 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr2_-_217560247 0.419 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr11_-_70507911 0.404 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_+_172068188 0.400 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr2_-_86565205 0.392 NM_001164730
REEP1
receptor accessory protein 1
chr2_-_1748285 0.384 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr3_-_64211111 0.380 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr8_-_23712297 0.369 NM_003155
STC1
stanniocalcin 1
chr3_+_179370779 0.357 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr11_-_70935807 0.353 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_99797530 0.339 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr1_-_45956795 0.337 NM_007170
TESK2
testis-specific kinase 2
chr2_-_213403280 0.330 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr7_-_105319608 0.322 NM_138495
ATXN7L1
ataxin 7-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
2.33 2.87e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.30 2.19e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.25 3.64e-03 GO:0009890 negative regulation of biosynthetic process
2.25 1.23e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.22 1.18e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.21 1.32e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.19 3.68e-02 GO:0010629 negative regulation of gene expression
2.02 4.16e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.01 1.85e-02 GO:0048699 generation of neurons
2.00 5.18e-03 GO:0009892 negative regulation of metabolic process
1.96 2.70e-02 GO:0031324 negative regulation of cellular metabolic process
1.94 3.52e-02 GO:0022008 neurogenesis
1.77 1.85e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.75 7.56e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.75 1.38e-02 GO:0007399 nervous system development
1.74 1.77e-06 GO:0031326 regulation of cellular biosynthetic process
1.73 1.70e-06 GO:0009889 regulation of biosynthetic process
1.69 3.87e-05 GO:0010468 regulation of gene expression
1.69 2.60e-04 GO:0051252 regulation of RNA metabolic process
1.69 6.31e-04 GO:0006355 regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.28 1.23e-02 GO:0005634 nucleus
1.13 1.71e-02 GO:0005622 intracellular
1.13 3.55e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.65 1.10e-02 GO:0016564 transcription repressor activity
2.34 1.35e-02 GO:0008289 lipid binding
2.25 3.72e-02 GO:0004674 protein serine/threonine kinase activity
2.09 6.18e-05 GO:0030528 transcription regulator activity
2.03 3.56e-04 GO:0001071 nucleic acid binding transcription factor activity
2.03 3.56e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 2.06e-04 GO:0008270 zinc ion binding
1.56 2.32e-03 GO:0046914 transition metal ion binding
1.37 9.62e-03 GO:0046872 metal ion binding
1.36 1.68e-02 GO:0043169 cation binding
1.35 1.90e-02 GO:0043167 ion binding
1.32 3.50e-06 GO:0005515 protein binding
1.19 3.26e-07 GO:0005488 binding