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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 0.998

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_+_42086533	2.593		SRSF6	serine/arginine-rich splicing factor 6
chr3_+_49449753	2.518		TCTA	T-cell leukemia translocation altered gene
chr3_+_49449638	2.245	NM_022171	TCTA	T-cell leukemia translocation altered gene
chr1_+_61547625	1.594	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr4_-_149363498	1.581	NM_000901 NM_001166104	NR3C2	nuclear receptor subfamily 3, group C, member 2
chr11_-_46867788	1.414		CKAP5	cytoskeleton associated protein 5
chr22_+_42372763	1.400	NM_019106 NM_145733	SEPT3	septin 3
chr5_-_134914447	1.354		CXCL14	chemokine (C-X-C motif) ligand 14
chr22_-_39548448	1.327	NM_175709	CBX7	chromobox homolog 7
chr13_-_36705432	1.324		DCLK1	doublecortin-like kinase 1
chr11_+_61276271	1.279	NM_001145077	LRRC10B	leucine rich repeat containing 10B
chr10_-_104178569	1.274		PSD	pleckstrin and Sec7 domain containing
chr5_+_42423811	1.268	NM_000163	GHR	growth hormone receptor
chr3_-_45267068	1.223		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr1_-_1535446	1.199	NM_001242659	LOC643988	uncharacterized LOC643988
chr1_+_228871109	1.113		RHOU	ras homolog gene family, member U
chr10_-_104178900	1.078	NM_002779	PSD	pleckstrin and Sec7 domain containing
chr20_-_3154169	1.071		ProSAPiP1	ProSAPiP1 protein
chr4_+_94750041	1.065	NM_005172	ATOH1	atonal homolog 1 (Drosophila)
chr11_-_2291809	1.056		ASCL2	achaete-scute complex homolog 2 (Drosophila)
chr18_+_23806385	1.030	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr6_-_90121656	0.996		RRAGD	Ras-related GTP binding D
chrX_-_136113832	0.978	NM_054021	GPR101	G protein-coupled receptor 101
chr5_+_151151483	0.978		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr7_-_73184535	0.954	NM_001306	CLDN3	claudin 3
chr4_-_105412466	0.954	NM_025212	CXXC4	CXXC finger protein 4
chr17_+_72667255	0.940	NM_175738	RAB37	RAB37, member RAS oncogene family
chr5_-_159739482	0.927	NM_024565	CCNJL	cyclin J-like
chr1_-_92351476	0.926		TGFBR3	transforming growth factor, beta receptor III
chr11_+_62104773	0.912	NM_001083926 NM_025080	ASRGL1	asparaginase like 1
chr3_+_14444083	0.911	NM_001134367 NM_001134368 NM_003043	SLC6A6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr3_-_171177851	0.905	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr19_-_18314731	0.895	NM_002866	RAB3A	RAB3A, member RAS oncogene family
chr10_+_12391728	0.894		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr20_+_32077780	0.894		CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr14_+_103243832	0.885		TRAF3	TNF receptor-associated factor 3
chr20_+_42086468	0.881	NM_006275	SRSF6	serine/arginine-rich splicing factor 6
chr11_-_2292181	0.877	NM_005170	ASCL2	achaete-scute complex homolog 2 (Drosophila)
chr14_-_54421269	0.876	NM_130851	BMP4	bone morphogenetic protein 4
chr2_+_85766291	0.871		MAT2A	methionine adenosyltransferase II, alpha
chr7_-_131241321	0.866	NM_001018111 NM_005397	PODXL	podocalyxin-like
chr5_+_151151516	0.864		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr14_-_21852085	0.856		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr1_+_183774214	0.849		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr6_-_86352656	0.839		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_-_134914968	0.801	NM_004887	CXCL14	chemokine (C-X-C motif) ligand 14
chr10_-_103879933	0.798	NM_001113407	LDB1	LIM domain binding 1
chr16_+_30710461	0.796	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr17_+_260092	0.781	NM_001013672	C17orf97	chromosome 17 open reading frame 97
chr3_-_45267804	0.759	NM_015444	TMEM158	transmembrane protein 158 (gene/pseudogene)
chr5_+_151151511	0.756		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151514	0.753		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr6_+_126070813	0.751		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr16_+_30709913	0.748
chr10_+_12391708	0.747		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr6_+_126070724	0.745	NM_012259	HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr1_+_227127959	0.744		ADCK3	aarF domain containing kinase 3
chr6_-_6007632	0.739	NM_016588	NRN1	neuritin 1
chr6_-_136610894	0.737		BCLAF1	BCL2-associated transcription factor 1
chr19_+_45909466	0.723	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr12_-_25348031	0.710	NM_001082972 NM_001082973 NM_001204101 NM_001204102 NM_018272	CASC1	cancer susceptibility candidate 1
chr5_+_151151462	0.704	NM_005754 NM_198395	G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr3_-_45267620	0.699		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr22_-_19512001	0.699		CLDN5	claudin 5
chr1_+_218519576	0.687		TGFB2	transforming growth factor, beta 2
chr9_+_4490193	0.687	NM_004170	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_219433302	0.678		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr5_+_42424553	0.677	NM_001242399 NM_001242400	GHR	growth hormone receptor
chr1_+_2518464	0.677		FAM213B	family with sequence similarity 213, member B
chr1_+_2518071	0.675	NM_001195736 NM_001195737 NM_001195738 NM_001195740 NM_001195741 NM_152371	FAM213B	family with sequence similarity 213, member B
chr8_+_120885899	0.672	NM_022783	DEPTOR	DEP domain containing MTOR-interacting protein
chr6_-_43543749	0.665		XPO5	exportin 5
chr18_-_71814948	0.663	NM_152676 NM_001142958	FBXO15	F-box protein 15
chr1_-_223537400	0.661	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr14_-_21852161	0.659		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr1_-_46598250	0.653	NM_003629 NM_001114172	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr16_-_4322695	0.651		TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chrX_-_112084006	0.650	NM_133265	AMOT	angiomotin
chr1_-_109656478	0.646	NM_001122961	C1orf194	chromosome 1 open reading frame 194
chr6_-_86352650	0.643		SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_83350452	0.639		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr6_-_90121966	0.638	NM_021244	RRAGD	Ras-related GTP binding D
chr4_+_156588811	0.624	NM_001130684	GUCY1A3	guanylate cyclase 1, soluble, alpha 3
chr5_+_42425093	0.615	NM_001242401	GHR	growth hormone receptor
chr2_+_29117503	0.613	NM_015131	WDR43	WD repeat domain 43
chr15_+_41952572	0.609	NM_001080541 NM_001164273	MGA	MAX gene associated
chr17_-_39203423	0.606	NM_001123387	KRTAP2-1	keratin associated protein 2-1
chr9_-_140196702	0.604	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr20_+_36531548	0.602		VSTM2L	V-set and transmembrane domain containing 2 like
chr11_-_76091866	0.599	NM_004705	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr2_-_73460326	0.586	NM_032319	PRADC1	protease-associated domain containing 1
chrX_-_54209639	0.582	NM_017848 NM_198456	FAM120C	family with sequence similarity 120C
chr16_-_52580805	0.579	NM_001080430	TOX3	TOX high mobility group box family member 3
chr12_+_124457568	0.579	NM_001204299 NM_001204298 NM_152437	ZNF664-FAM101A ZNF664	protein FAM101A zinc finger protein 664
chr6_+_126070738	0.574		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr20_-_20693122	0.573	NM_020343	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_+_17757494	0.571	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr20_+_36531498	0.571	NM_080607	VSTM2L	V-set and transmembrane domain containing 2 like
chr22_-_19511777	0.570		CLDN5	claudin 5
chr1_+_227127999	0.566		ADCK3	aarF domain containing kinase 3
chr13_+_28366779	0.566	NM_145657	GSX1	GS homeobox 1
chr7_-_122526781	0.564	NM_001009571 NM_001167940 NM_017954	CADPS2	Ca++-dependent secretion activator 2
chr6_-_86352982	0.564	NM_001159677 NM_006372	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_-_13390189	0.563	NM_001195602 NM_001195604 NM_012247	SEPHS1	selenophosphate synthetase 1
chr3_+_134514044	0.563	NM_004441	EPHB1	EPH receptor B1
chr22_+_20105068	0.562		RANBP1	RAN binding protein 1
chr5_-_130970803	0.559		RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr17_+_36861857	0.552	NM_005937	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr8_+_110346549	0.552	NM_001193557 NM_020189	ENY2	enhancer of yellow 2 homolog (Drosophila)
chr1_-_115053677	0.551		TRIM33	tripartite motif containing 33
chr19_-_7990974	0.548	NM_206833	CTXN1	cortexin 1
chr12_+_54943358	0.548		PDE1B	phosphodiesterase 1B, calmodulin-dependent
chr19_+_49956472	0.545	NM_001145396 NM_153329	ALDH16A1	aldehyde dehydrogenase 16 family, member A1
chr16_+_67282774	0.542	NM_004594	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr2_-_172016904	0.542		TLK1	tousled-like kinase 1
chr19_-_39340362	0.542		HNRNPL	heterogeneous nuclear ribonucleoprotein L
chr19_-_14316980	0.539	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr1_+_1447495	0.535	NM_001170535 NM_018188	ATAD3A	ATPase family, AAA domain containing 3A
chr19_+_49956492	0.535		ALDH16A1	aldehyde dehydrogenase 16 family, member A1
chrX_-_140271275	0.534		LDOC1	leucine zipper, down-regulated in cancer 1
chr19_-_7293876	0.532	NM_000208 NM_001079817	INSR	insulin receptor
chr6_-_43543600	0.531		XPO5	exportin 5
chr8_+_85095452	0.531	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr5_+_134181729	0.530		C5orf24	chromosome 5 open reading frame 24
chr17_+_72427535	0.529	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr16_+_22825806	0.529	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_19774472	0.528		ATP13A1	ATPase type 13A1
chr19_-_10341947	0.528	NM_004230	S1PR2	sphingosine-1-phosphate receptor 2
chr1_+_1447871	0.527	NM_001170536	ATAD3A	ATPase family, AAA domain containing 3A
chr15_-_93632161	0.525	NM_020211	RGMA	RGM domain family, member A
chr14_+_60975937	0.522	NM_007374	SIX6	SIX homeobox 6
chr10_+_26505235	0.522	NM_000818 NM_001134366	GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr19_-_19774501	0.520	NM_020410	ATP13A1	ATPase type 13A1
chr8_+_67341244	0.519	NM_015169	RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr6_-_119670897	0.519	NM_005907	MAN1A1	mannosidase, alpha, class 1A, member 1
chr20_+_13976014	0.517	NM_080676	MACROD2	MACRO domain containing 2
chr10_+_105156382	0.517	NM_014976	PDCD11	programmed cell death 11
chr6_-_136610932	0.516	NM_001077440 NM_001077441 NM_014739	BCLAF1	BCL2-associated transcription factor 1
chr6_-_90121911	0.516		RRAGD	Ras-related GTP binding D
chr1_+_227127937	0.514	NM_020247	ADCK3	aarF domain containing kinase 3
chr1_-_115053758	0.514	NM_015906 NM_033020	TRIM33	tripartite motif containing 33
chr8_+_85095501	0.512	NM_173848	RALYL	RALY RNA binding protein-like
chr10_+_105156430	0.509		PDCD11	programmed cell death 11
chr5_+_127419407	0.508	NM_001046	SLC12A2	solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr12_-_9102262	0.507	NM_001207024 NM_002355	M6PR	mannose-6-phosphate receptor (cation dependent)
chr15_+_84115979	0.506	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr1_+_227127993	0.505		ADCK3	aarF domain containing kinase 3
chr9_+_33025270	0.504		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr16_+_776957	0.503	NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr12_+_110906203	0.502	NM_013300	C12orf24	chromosome 12 open reading frame 24
chr14_+_103243813	0.501	NM_001199427 NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr5_-_81046943	0.499	NM_012446	SSBP2	single-stranded DNA binding protein 2
chr4_+_55523906	0.499	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr7_+_91763851	0.498		LOC613126	uncharacterized LOC613126
chr2_-_33824294	0.495	NM_015475	FAM98A	family with sequence similarity 98, member A
chr15_-_93631751	0.494	NM_001166287	RGMA	RGM domain family, member A
chr12_-_88974094	0.493	NM_000899 NM_003994	KITLG	KIT ligand
chr20_+_32077904	0.491	NM_001032999	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr7_+_145813828	0.490		CNTNAP2	contactin associated protein-like 2
chr17_+_53342356	0.490		HLF	hepatic leukemia factor
chr19_-_46088084	0.484	NM_001017989 NM_025136	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr6_+_43484834	0.484		POLR1C	polymerase (RNA) I polypeptide C, 30kDa
chr16_+_77225094	0.484		MON1B	MON1 homolog B (yeast)
chr13_-_36705513	0.481	NM_004734	DCLK1	doublecortin-like kinase 1
chr6_+_43484776	0.480	NM_203290	POLR1C	polymerase (RNA) I polypeptide C, 30kDa
chr11_+_819563	0.476		PNPLA2	patatin-like phospholipase domain containing 2
chr9_+_33025302	0.476		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr12_-_9102193	0.472		M6PR	mannose-6-phosphate receptor (cation dependent)
chr2_+_198570027	0.468	NM_138395	MARS2	methionyl-tRNA synthetase 2, mitochondrial
chr20_+_58179601	0.467	NM_080672	PHACTR3	phosphatase and actin regulator 3
chr11_+_73357222	0.467	NM_001130033 NM_021200	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr5_-_81046858	0.467		SSBP2	single-stranded DNA binding protein 2
chr16_+_22825481	0.466		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr7_+_44144002	0.462		AEBP1	AE binding protein 1
chr3_-_66024508	0.461	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_205538164	0.460		MFSD4	major facilitator superfamily domain containing 4
chr14_+_77648127	0.458		TMEM63C	transmembrane protein 63C
chr15_+_65822842	0.455		PTPLAD1	protein tyrosine phosphatase-like A domain containing 1
chr13_-_95953572	0.455	NM_001105515 NM_005845	ABCC4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr1_+_1447537	0.454		ATAD3A ATAD3B	ATPase family, AAA domain containing 3A ATPase family, AAA domain containing 3B
chr12_+_110906659	0.453		C12orf24	chromosome 12 open reading frame 24
chr11_+_66624501	0.451		LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr1_+_221052845	0.449		HLX	H2.0-like homeobox
chr12_+_110906532	0.448		C12orf24	chromosome 12 open reading frame 24
chr22_+_45098046	0.448	NM_181333	PRR5	proline rich 5 (renal)
chr11_-_86383355	0.447	NM_006680	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr2_-_27712520	0.447	NM_015662	IFT172	intraflagellar transport 172 homolog (Chlamydomonas)
chr14_-_65569056	0.445		MAX	MYC associated factor X
chr9_-_89562103	0.445	NM_002048	GAS1	growth arrest-specific 1
chr22_-_29196452	0.444		XBP1	X-box binding protein 1
chr7_-_117513466	0.442		CTTNBP2	cortactin binding protein 2
chr1_-_92351613	0.439	NM_001195683 NM_003243	TGFBR3	transforming growth factor, beta receptor III
chr16_-_4323000	0.439	NM_003223	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr13_+_37006408	0.438	NM_001111045 NM_003914	CCNA1	cyclin A1
chr4_-_54232007	0.436	NM_152540	SCFD2	sec1 family domain containing 2
chr1_+_9648931	0.434	NM_001010866 NM_001130924	TMEM201	transmembrane protein 201
chr20_-_45318135	0.433	NM_033550	TP53RK	TP53 regulating kinase
chr3_-_72897575	0.432		SHQ1	SHQ1 homolog (S. cerevisiae)
chr6_-_107435635	0.428	NM_001080450	BEND3	BEN domain containing 3
chr21_-_47743753	0.427	NM_058180	C21orf58	chromosome 21 open reading frame 58

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	3.41e-18	GO:0044260	cellular macromolecule metabolic process
1.57	1.77e-16	GO:0010467	gene expression
1.56	1.03e-14	GO:0016070	RNA metabolic process
1.12	2.22e-12	GO:0009987	cellular process
1.39	2.66e-12	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	2.84e-12	GO:0090304	nucleic acid metabolic process
1.26	1.15e-11	GO:0043170	macromolecule metabolic process
1.22	1.52e-11	GO:0044237	cellular metabolic process
1.32	1.55e-09	GO:0034641	cellular nitrogen compound metabolic process
1.29	5.20e-08	GO:0006807	nitrogen compound metabolic process
1.27	6.59e-08	GO:0031323	regulation of cellular metabolic process
1.28	8.31e-08	GO:0060255	regulation of macromolecule metabolic process
1.73	1.04e-07	GO:0006396	RNA processing
1.61	1.20e-07	GO:0006351	transcription, DNA-dependent
1.27	2.19e-07	GO:0080090	regulation of primary metabolic process
1.25	4.58e-07	GO:0019222	regulation of metabolic process
1.55	6.93e-07	GO:0032774	RNA biosynthetic process
1.17	1.63e-06	GO:0044238	primary metabolic process
1.33	2.05e-06	GO:0051252	regulation of RNA metabolic process
1.40	2.41e-06	GO:0034645	cellular macromolecule biosynthetic process
1.16	2.87e-06	GO:0050794	regulation of cellular process
1.31	3.08e-06	GO:0010468	regulation of gene expression
1.53	3.17e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.86	5.15e-06	GO:0006397	mRNA processing
1.38	5.60e-06	GO:0009059	macromolecule biosynthetic process
1.15	6.07e-06	GO:0008152	metabolic process
1.30	7.58e-06	GO:0044267	cellular protein metabolic process
1.35	1.33e-05	GO:0043412	macromolecule modification
1.46	2.42e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.69	2.48e-05	GO:0016071	mRNA metabolic process
1.28	2.52e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43	2.87e-05	GO:0009893	positive regulation of metabolic process
1.14	3.08e-05	GO:0050789	regulation of biological process
1.28	3.31e-05	GO:0071842	cellular component organization at cellular level
1.13	3.53e-05	GO:0065007	biological regulation
1.28	3.55e-05	GO:0071841	cellular component organization or biogenesis at cellular level
1.28	3.57e-05	GO:0031326	regulation of cellular biosynthetic process
1.27	7.47e-05	GO:0009889	regulation of biosynthetic process
1.34	9.56e-05	GO:0006464	protein modification process
1.26	1.06e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.27	2.04e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.28	2.10e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.29	4.18e-04	GO:0006355	regulation of transcription, DNA-dependent
1.35	9.49e-04	GO:0007399	nervous system development
1.54	1.14e-03	GO:0051254	positive regulation of RNA metabolic process
1.53	1.16e-03	GO:0010628	positive regulation of gene expression
1.21	1.27e-03	GO:0016043	cellular component organization
1.21	2.08e-03	GO:0071840	cellular component organization or biogenesis
1.38	2.28e-03	GO:0031325	positive regulation of cellular metabolic process
1.78	2.54e-03	GO:0008380	RNA splicing
1.53	3.39e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.48	4.77e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.68	7.58e-03	GO:0016568	chromatin modification
1.59	1.05e-02	GO:0006325	chromatin organization
1.58	1.29e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.42	1.31e-02	GO:0009891	positive regulation of biosynthetic process
1.74	1.39e-02	GO:0006366	transcription from RNA polymerase II promoter
1.23	1.50e-02	GO:0044249	cellular biosynthetic process
1.42	1.95e-02	GO:0031328	positive regulation of cellular biosynthetic process
1.49	1.99e-02	GO:0051276	chromosome organization
1.44	2.06e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17	2.21e-02	GO:0032502	developmental process
1.54	2.56e-02	GO:0007417	central nervous system development
1.20	2.77e-02	GO:0019538	protein metabolic process
1.49	2.99e-02	GO:0000902	cell morphogenesis
1.42	4.06e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.21	4.08e-02	GO:0048518	positive regulation of biological process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.15	1.37e-23	GO:0005622	intracellular
1.31	2.40e-22	GO:0005634	nucleus
1.20	2.82e-22	GO:0043231	intracellular membrane-bounded organelle
1.20	3.15e-22	GO:0043227	membrane-bounded organelle
1.14	1.30e-20	GO:0044424	intracellular part
1.17	1.72e-20	GO:0043226	organelle
1.17	2.53e-20	GO:0043229	intracellular organelle
1.45	1.99e-13	GO:0044428	nuclear part
1.41	4.51e-12	GO:0031974	membrane-enclosed lumen
1.47	4.90e-12	GO:0031981	nuclear lumen
1.41	6.06e-12	GO:0070013	intracellular organelle lumen
1.40	3.63e-11	GO:0043233	organelle lumen
1.50	1.82e-09	GO:0005654	nucleoplasm
1.20	2.45e-08	GO:0044446	intracellular organelle part
1.19	8.12e-08	GO:0044422	organelle part
1.62	2.54e-07	GO:0044451	nucleoplasm part
1.12	1.05e-05	GO:0005737	cytoplasm
1.04	2.73e-05	GO:0044464	cell part
1.04	2.86e-05	GO:0005623	cell
1.88	6.20e-04	GO:0016604	nuclear body
2.17	1.82e-03	GO:0016607	nuclear speck
1.54	1.93e-03	GO:0030529	ribonucleoprotein complex
1.12	8.44e-03	GO:0044444	cytoplasmic part
4.02	1.99e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.16	2.34e-02	GO:0032991	macromolecular complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.38	1.33e-16	GO:0003676	nucleic acid binding
1.10	8.73e-10	GO:0005488	binding
1.36	5.89e-09	GO:0000166	nucleotide binding
1.35	8.44e-09	GO:0003677	DNA binding
1.64	8.47e-09	GO:0003723	RNA binding
1.16	1.20e-08	GO:0005515	protein binding
1.51	5.02e-07	GO:0030528	transcription regulator activity
1.45	1.76e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.30	2.18e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.31	3.50e-04	GO:0016740	transferase activity
1.42	3.64e-04	GO:0001071	nucleic acid binding transcription factor activity
1.42	3.64e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.28	7.40e-04	GO:0032553	ribonucleotide binding
1.28	7.40e-04	GO:0032555	purine ribonucleotide binding
1.74	8.52e-04	GO:0016563	transcription activator activity
1.28	8.90e-04	GO:0017076	purine nucleotide binding
1.47	7.48e-03	GO:0004672	protein kinase activity
1.43	8.54e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.56	9.43e-03	GO:0004674	protein serine/threonine kinase activity
1.87	1.89e-02	GO:0016741	transferase activity, transferring one-carbon groups
1.89	1.94e-02	GO:0008168	methyltransferase activity
1.42	2.23e-02	GO:0043565	sequence-specific DNA binding
1.39	2.40e-02	GO:0016301	kinase activity
6.20	3.72e-02	GO:0034713	type I transforming growth factor beta receptor binding