Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 0.998


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_150849147-0.711.3e-05Click!
ARNT2chr15_+_80696569-0.595.6e-04Click!
AHRchr7_+_173381820.251.8e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_42086533 2.593 SRSF6
serine/arginine-rich splicing factor 6
chr3_+_49449753 2.518 TCTA
T-cell leukemia translocation altered gene
chr3_+_49449638 2.245 NM_022171
 TCTA
T-cell leukemia translocation altered gene
chr1_+_61547625 1.594 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr4_-_149363498 1.581 NM_000901
NM_001166104
 NR3C2

nuclear receptor subfamily 3, group C, member 2

chr11_-_46867788 1.414 CKAP5
cytoskeleton associated protein 5
chr22_+_42372763 1.400 NM_019106
NM_145733
 SEPT3

septin 3

chr5_-_134914447 1.354 CXCL14
chemokine (C-X-C motif) ligand 14
chr22_-_39548448 1.327 NM_175709
 CBX7
chromobox homolog 7
chr13_-_36705432 1.324 DCLK1
doublecortin-like kinase 1
chr11_+_61276271 1.279 NM_001145077
 LRRC10B
leucine rich repeat containing 10B
chr10_-_104178569 1.274 PSD
pleckstrin and Sec7 domain containing
chr5_+_42423811 1.268 NM_000163
 GHR
growth hormone receptor
chr3_-_45267068 1.223 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr1_-_1535446 1.199 NM_001242659
 LOC643988
uncharacterized LOC643988
chr1_+_228871109 1.113 RHOU
ras homolog gene family, member U
chr10_-_104178900 1.078 NM_002779
 PSD
pleckstrin and Sec7 domain containing
chr20_-_3154169 1.071 ProSAPiP1
ProSAPiP1 protein
chr4_+_94750041 1.065 NM_005172
 ATOH1
atonal homolog 1 (Drosophila)
chr11_-_2291809 1.056 ASCL2
achaete-scute complex homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 67 entries
enrichment   p-value GO term description
1.86 5.15e-06 GO:0006397 mRNA processing
1.78 2.54e-03 GO:0008380 RNA splicing
1.74 1.39e-02 GO:0006366 transcription from RNA polymerase II promoter
1.73 1.04e-07 GO:0006396 RNA processing
1.69 2.48e-05 GO:0016071 mRNA metabolic process
1.68 7.58e-03 GO:0016568 chromatin modification
1.61 1.20e-07 GO:0006351 transcription, DNA-dependent
1.59 1.05e-02 GO:0006325 chromatin organization
1.58 1.29e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.57 1.77e-16 GO:0010467 gene expression
1.56 1.03e-14 GO:0016070 RNA metabolic process
1.55 6.93e-07 GO:0032774 RNA biosynthetic process
1.54 1.14e-03 GO:0051254 positive regulation of RNA metabolic process
1.54 2.56e-02 GO:0007417 central nervous system development
1.53 3.17e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.53 1.16e-03 GO:0010628 positive regulation of gene expression
1.53 3.39e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.49 1.99e-02 GO:0051276 chromosome organization
1.49 2.99e-02 GO:0000902 cell morphogenesis
1.48 4.77e-03 GO:0010557 positive regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
4.02 1.99e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
2.17 1.82e-03 GO:0016607 nuclear speck
1.88 6.20e-04 GO:0016604 nuclear body
1.62 2.54e-07 GO:0044451 nucleoplasm part
1.54 1.93e-03 GO:0030529 ribonucleoprotein complex
1.50 1.82e-09 GO:0005654 nucleoplasm
1.47 4.90e-12 GO:0031981 nuclear lumen
1.45 1.99e-13 GO:0044428 nuclear part
1.41 4.51e-12 GO:0031974 membrane-enclosed lumen
1.41 6.06e-12 GO:0070013 intracellular organelle lumen
1.40 3.63e-11 GO:0043233 organelle lumen
1.31 2.40e-22 GO:0005634 nucleus
1.20 2.82e-22 GO:0043231 intracellular membrane-bounded organelle
1.20 3.15e-22 GO:0043227 membrane-bounded organelle
1.20 2.45e-08 GO:0044446 intracellular organelle part
1.19 8.12e-08 GO:0044422 organelle part
1.17 1.72e-20 GO:0043226 organelle
1.17 2.53e-20 GO:0043229 intracellular organelle
1.16 2.34e-02 GO:0032991 macromolecular complex
1.15 1.37e-23 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
6.20 3.72e-02 GO:0034713 type I transforming growth factor beta receptor binding
1.89 1.94e-02 GO:0008168 methyltransferase activity
1.87 1.89e-02 GO:0016741 transferase activity, transferring one-carbon groups
1.74 8.52e-04 GO:0016563 transcription activator activity
1.64 8.47e-09 GO:0003723 RNA binding
1.56 9.43e-03 GO:0004674 protein serine/threonine kinase activity
1.51 5.02e-07 GO:0030528 transcription regulator activity
1.47 7.48e-03 GO:0004672 protein kinase activity
1.45 1.76e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.43 8.54e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.42 3.64e-04 GO:0001071 nucleic acid binding transcription factor activity
1.42 3.64e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.42 2.23e-02 GO:0043565 sequence-specific DNA binding
1.39 2.40e-02 GO:0016301 kinase activity
1.38 1.33e-16 GO:0003676 nucleic acid binding
1.36 5.89e-09 GO:0000166 nucleotide binding
1.35 8.44e-09 GO:0003677 DNA binding
1.31 3.50e-04 GO:0016740 transferase activity
1.30 2.18e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.28 7.40e-04 GO:0032553 ribonucleotide binding