Motif ID: AIRE.p2

Z-value: 0.639


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AIREchr21_+_457101470.355.9e-02Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_216241321 1.831 FN1
fibronectin 1
chr1_+_84630575 1.185 NM_001242860
NM_001242861
 PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr6_-_46703429 1.044 NM_001168357
 PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr19_-_49865638 0.845 NM_003598
 TEAD2
TEA domain family member 2
chr4_-_103245468 0.814 NM_001135148
 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_-_64727608 0.740 NM_001037225
 C11orf85
chromosome 11 open reading frame 85
chr19_-_14785626 0.657 NM_032571
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr1_-_144997110 0.628 NM_001195260
 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_7110164 0.615 NM_014469
 RBMXL2
RNA binding motif protein, X-linked-like 2
chr19_-_39826676 0.604 NM_004877
 GMFG
glia maturation factor, gamma
chr3_+_189507448 0.568 NM_001114980
NM_001114981
NM_001114982
 TP63


tumor protein p63


chr1_-_17308072 0.556 NM_001135247
NM_017459
 MFAP2

microfibrillar-associated protein 2

chr16_-_58328879 0.530 NM_001080492
 PRSS54
protease, serine, 54
chr14_-_60632019 0.516 DHRS7
dehydrogenase/reductase (SDR family) member 7
chr11_-_59612925 0.505 NM_005142
 GIF
gastric intrinsic factor (vitamin B synthesis)
chr15_-_50411405 0.498 NM_024837
 ATP8B4
ATPase, class I, type 8B, member 4
chr17_+_41006094 0.496 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr18_-_61311465 0.489 NM_002974
 SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr1_+_84609941 0.469 NM_182948
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_70146216 0.443 NM_001207004
NM_053039
 UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.16 3.58e-04 GO:0006952 defense response
2.11 2.80e-03 GO:0006955 immune response
1.84 2.42e-03 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.68 4.29e-02 GO:0044421 extracellular region part
1.66 5.10e-05 GO:0005576 extracellular region

Nothing significant found in function category.