Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.311


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_150849211-0.711.1e-05Click!
MAXchr14_-_655692210.478.3e-03Click!
BHLHE40chr3_+_5021096-0.134.9e-01Click!
MYCchr8_+_1287484760.135.0e-01Click!
USF1chr1_-_161015688-0.115.6e-01Click!
ARNT2chr15_+_80696569-0.105.8e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_58146110 5.659 CDK4
cyclin-dependent kinase 4
chr12_-_58146118 5.436 NM_000075
 CDK4
cyclin-dependent kinase 4
chr12_-_58146025 5.386 CDK4
cyclin-dependent kinase 4
chr12_-_58146108 4.229 CDK4
cyclin-dependent kinase 4
chr2_-_10588451 4.146 NM_002539
 ODC1
ornithine decarboxylase 1
chr9_-_131709783 3.563 NM_014908
 DOLK
dolichol kinase
chr17_+_46970128 3.415 NM_001002027
NM_005175
 ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chrX_-_100603956 3.362 NM_004085
 TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr9_+_131709991 3.085 NUP188
nucleoporin 188kDa
chr9_+_131709970 3.054 NM_015354
 NUP188
nucleoporin 188kDa
chr1_-_11120081 3.018 NM_003132
 SRM
spermidine synthase
chr2_+_27440342 2.987 CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_11120047 2.653 SRM
spermidine synthase
chr19_+_7587436 2.504 NM_020533
 MCOLN1
mucolipin 1
chr16_+_89778242 2.415 LOC100128881
uncharacterized LOC100128881
chr16_-_1525020 2.400 CLCN7
chloride channel 7
chr3_+_127317271 2.291 MCM2
minichromosome maintenance complex component 2
chr4_+_100871625 2.256 LOC256880
uncharacterized LOC256880
chr5_+_149340287 2.251 NM_000112
 SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr11_+_61560108 2.248 NM_004111
 FEN1
flap structure-specific endonuclease 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
5.07 1.02e-03 GO:0015682 ferric iron transport
5.07 1.02e-03 GO:0033572 transferrin transport
2.80 7.18e-04 GO:0042254 ribosome biogenesis
2.66 3.01e-02 GO:0000041 transition metal ion transport
2.39 3.20e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.31 3.10e-03 GO:0022613 ribonucleoprotein complex biogenesis
2.31 8.51e-03 GO:0051169 nuclear transport
2.27 1.78e-02 GO:0006913 nucleocytoplasmic transport
2.26 4.30e-03 GO:0071843 cellular component biogenesis at cellular level
2.13 7.75e-03 GO:0018130 heterocycle biosynthetic process
2.12 4.49e-02 GO:0000375 RNA splicing, via transesterification reactions
2.10 8.04e-05 GO:0044419 interspecies interaction between organisms
2.06 4.09e-02 GO:0051186 cofactor metabolic process
1.94 2.58e-03 GO:0044271 cellular nitrogen compound biosynthetic process
1.89 2.04e-02 GO:0006520 cellular amino acid metabolic process
1.83 2.91e-05 GO:0006396 RNA processing
1.80 7.12e-04 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.80 2.18e-03 GO:0006753 nucleoside phosphate metabolic process
1.80 2.18e-03 GO:0009117 nucleotide metabolic process
1.79 1.88e-02 GO:0072521 purine-containing compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
9.75 1.09e-02 GO:0042719 mitochondrial intermembrane space protein transporter complex
8.35 3.56e-02 GO:0005666 DNA-directed RNA polymerase III complex
5.85 7.32e-04 GO:0033176 proton-transporting V-type ATPase complex
5.85 2.86e-02 GO:0030684 preribosome
5.20 2.43e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
3.54 1.72e-02 GO:0016469 proton-transporting two-sector ATPase complex
2.25 8.79e-03 GO:0044437 vacuolar part
2.24 2.04e-05 GO:0000323 lytic vacuole
2.24 2.04e-05 GO:0005764 lysosome
2.20 2.39e-10 GO:0005730 nucleolus
2.16 8.61e-06 GO:0005773 vacuole
2.08 3.75e-03 GO:0016604 nuclear body
1.87 2.24e-05 GO:0030529 ribonucleoprotein complex
1.87 3.41e-03 GO:0019866 organelle inner membrane
1.85 1.33e-02 GO:0005743 mitochondrial inner membrane
1.78 1.87e-03 GO:0031966 mitochondrial membrane
1.75 2.10e-03 GO:0005740 mitochondrial envelope
1.73 1.67e-05 GO:0031967 organelle envelope
1.73 1.81e-05 GO:0044451 nucleoplasm part
1.72 2.10e-05 GO:0031975 envelope

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.20 3.86e-02 GO:0046961 proton-transporting ATPase activity, rotational mechanism
1.77 3.23e-07 GO:0003723 RNA binding
1.21 8.68e-09 GO:0005515 protein binding
1.15 4.11e-02 GO:0003824 catalytic activity
1.08 1.69e-03 GO:0005488 binding