Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 1.311


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2
BHLHB2 8553 basic helix-loop-helix domain containing, class B, 2
MAX 4149 MYC associated factor X
MYC 4609 v-myc myelocytomatosis viral oncogene homolog (avian)
USF1 7391 upstream transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNTchr1_-_150849211-0.711.1e-05Click!
MAXchr14_-_655692210.478.3e-03Click!
BHLHE40chr3_+_5021096-0.134.9e-01Click!
MYCchr8_+_1287484760.135.0e-01Click!
USF1chr1_-_161015688-0.115.6e-01Click!
ARNT2chr15_+_80696569-0.105.8e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_58146110 5.659 CDK4
cyclin-dependent kinase 4
chr12_-_58146118 5.436 NM_000075
CDK4
cyclin-dependent kinase 4
chr12_-_58146025 5.386 CDK4
cyclin-dependent kinase 4
chr12_-_58146108 4.229 CDK4
cyclin-dependent kinase 4
chr2_-_10588451 4.146 NM_002539
ODC1
ornithine decarboxylase 1
chr9_-_131709783 3.563 NM_014908
DOLK
dolichol kinase
chr17_+_46970128 3.415 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chrX_-_100603956 3.362 NM_004085
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr9_+_131709991 3.085 NUP188
nucleoporin 188kDa
chr9_+_131709970 3.054 NM_015354
NUP188
nucleoporin 188kDa
chr1_-_11120081 3.018 NM_003132
SRM
spermidine synthase
chr2_+_27440342 2.987 CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_11120047 2.653 SRM
spermidine synthase
chr19_+_7587436 2.504 NM_020533
MCOLN1
mucolipin 1
chr16_+_89778242 2.415 LOC100128881
uncharacterized LOC100128881
chr16_-_1525020 2.400 CLCN7
chloride channel 7
chr3_+_127317271 2.291 MCM2
minichromosome maintenance complex component 2
chr4_+_100871625 2.256 LOC256880
uncharacterized LOC256880
chr5_+_149340287 2.251 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr11_+_61560108 2.248 NM_004111
FEN1
flap structure-specific endonuclease 1
chr3_+_127317274 2.247 MCM2
minichromosome maintenance complex component 2
chr16_-_4897265 2.218 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chrX_-_100662905 2.156 NM_000169
GLA
galactosidase, alpha
chr3_+_127317212 2.099 NM_004526
MCM2
minichromosome maintenance complex component 2
chr16_-_5083933 2.051 NM_016256
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_+_150827138 2.013 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr1_-_154531083 2.002 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chrX_-_100662788 1.988 GLA
galactosidase, alpha
chr19_-_13227212 1.978 NM_001142554
NM_017722
NM_001136035
TRMT1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr1_-_53164014 1.975 SELRC1
Sel1 repeat containing 1
chr5_+_149340437 1.935 SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr16_-_5083913 1.916 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr11_+_66624501 1.909 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr6_+_160390128 1.869 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr7_+_27135672 1.868 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr9_-_130890401 1.851 NM_025072
PTGES2
prostaglandin E synthase 2
chr16_-_1525040 1.833 NM_001114331
NM_001287
CLCN7

chloride channel 7

chr14_-_20923266 1.826 NM_017807
OSGEP
O-sialoglycoprotein endopeptidase
chr8_-_126103873 1.821 KIAA0196
KIAA0196
chr3_+_184032319 1.812 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr2_-_71221833 1.799 TEX261
testis expressed 261
chr7_+_150759633 1.797 NM_001199693
NM_001199694
SLC4A2

solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)

chr17_+_7211693 1.784 NM_001143762
EIF5A
eukaryotic translation initiation factor 5A
chr6_-_7313352 1.768 NM_003144
SSR1
signal sequence receptor, alpha
chr1_+_1167622 1.766 NM_080605
B3GALT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr11_+_61560401 1.735 FEN1
flap structure-specific endonuclease 1
chr3_+_184032414 1.713 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr2_+_216176818 1.667 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr16_-_4588738 1.665 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr17_+_78075299 1.655 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr1_-_53163985 1.616 SELRC1
Sel1 repeat containing 1
chr2_+_216176808 1.615 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr18_+_56807115 1.604 NM_033280
SEC11C
SEC11 homolog C (S. cerevisiae)
chr8_-_71581354 1.577 LACTB2
lactamase, beta 2
chr8_-_126104004 1.573 KIAA0196
KIAA0196
chr17_+_46018888 1.542 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr11_+_61560352 1.540 FEN1
flap structure-specific endonuclease 1
chr17_-_4458618 1.540 NM_001105538
NM_014520
MYBBP1A

MYB binding protein (P160) 1a

chr19_-_40854283 1.530 NM_178830
C19orf47
chromosome 19 open reading frame 47
chr8_-_126103926 1.530 KIAA0196
KIAA0196
chr8_-_126104021 1.526 KIAA0196
KIAA0196
chr17_+_49230929 1.525 NME1
non-metastatic cells 1, protein (NM23A) expressed in
chr2_-_10588273 1.514 ODC1
ornithine decarboxylase 1
chr17_+_78075390 1.514 GAA
glucosidase, alpha; acid
chr11_-_71814335 1.485 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr10_+_104474297 1.464 NM_178858
SFXN2
sideroflexin 2
chr8_+_99129488 1.457 NM_001145860
NM_001145861
POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chrX_+_16804531 1.454 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr22_-_36903033 1.453 FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr16_+_28986024 1.453 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr6_-_43197178 1.446 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr2_+_113403433 1.436 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr3_+_50654600 1.412 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr11_+_20409075 1.411 NM_001145166
NM_001145167
NM_005788
PRMT3


protein arginine methyltransferase 3


chr16_-_58718607 1.409 NM_018231
SLC38A7
solute carrier family 38, member 7
chr8_+_104427612 1.407 DCAF13
DDB1 and CUL4 associated factor 13
chr8_-_126104045 1.389 NM_014846
KIAA0196
KIAA0196
chr8_+_104427659 1.362 DCAF13
DDB1 and CUL4 associated factor 13
chr3_+_50654589 1.348 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr17_+_7211260 1.334 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr1_-_11120076 1.330 SRM
spermidine synthase
chr2_-_238499317 1.327 RAB17
RAB17, member RAS oncogene family
chr4_-_103266396 1.318 NM_001135147
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr12_-_85306569 1.309 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chrX_-_100603673 1.306 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr17_+_42148097 1.304 NM_138387
G6PC3
glucose 6 phosphatase, catalytic, 3
chr6_-_31763415 1.302 VARS
valyl-tRNA synthetase
chr12_+_56862300 1.289 NM_207344
SPRYD4
SPRY domain containing 4
chr11_-_71814294 1.280 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr17_+_49230954 1.270 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough
chr19_+_10812111 1.270 NM_031209
QTRT1
queuine tRNA-ribosyltransferase 1
chr8_-_126104007 1.265 KIAA0196
KIAA0196
chr1_-_11120001 1.264 SRM
spermidine synthase
chr5_+_149737296 1.261 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr19_+_45909466 1.249 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr14_+_93799564 1.247 NM_020818
UNC79
unc-79 homolog (C. elegans)
chr22_-_36903086 1.247 NM_024955
NM_001102371
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr12_+_132413776 1.216 NM_001002019
NM_025215
PUS1

pseudouridylate synthase 1

chr1_-_226111803 1.195 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr17_+_49337882 1.194 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr1_-_26232643 1.187 NM_203401
STMN1
stathmin 1
chr17_-_41132019 1.181 NM_025267
AARSD1
alanyl-tRNA synthetase domain containing 1
chr2_+_68384986 1.179 NM_020143
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr1_-_53164023 1.174 NM_023077
SELRC1
Sel1 repeat containing 1
chr17_+_49337892 1.174 NM_016001
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr12_-_65153148 1.172 GNS
glucosamine (N-acetyl)-6-sulfatase
chr3_-_51975879 1.158 NM_004704
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr8_-_71581419 1.156 NM_016027
LACTB2
lactamase, beta 2
chr19_-_2783313 1.149 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_-_71814371 1.145 NM_017907
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr3_-_124931562 1.145 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr4_-_4291731 1.141 NM_001145725
LYAR
Ly1 antibody reactive homolog (mouse)
chr1_-_155210887 1.135 GBA
glucosidase, beta, acid
chr16_-_1525006 1.135 CLCN7
chloride channel 7
chr2_+_27440233 1.135 NM_004341
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr2_-_193059249 1.135 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr9_+_115913266 1.133 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr4_-_4291889 1.133 NM_017816
LYAR
Ly1 antibody reactive homolog (mouse)
chr3_+_50654558 1.131 NM_001243925
NM_004635
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chr4_-_4291817 1.130 LYAR
Ly1 antibody reactive homolog (mouse)
chr19_-_2783332 1.129 NM_003021
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr10_+_51827710 1.126 FAM21A
family with sequence similarity 21, member A
chr6_-_35656677 1.123 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr15_-_83316621 1.120 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr17_+_1628032 1.109 NM_001163809
WDR81
WD repeat domain 81
chr1_-_155211049 1.107 NM_001171812
NM_000157
GBA

glucosidase, beta, acid

chr19_-_40854410 1.106 C19orf47
chromosome 19 open reading frame 47
chr19_-_2783225 1.105 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr11_+_20409212 1.104 PRMT3
protein arginine methyltransferase 3
chr8_+_67341244 1.097 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr19_-_48018163 1.095 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr3_+_184032243 1.084 NM_001194946
NM_001194947
NM_198241
NM_198242
NM_198244
EIF4G1




eukaryotic translation initiation factor 4 gamma, 1




chr8_+_22224758 1.074 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr3_-_49967194 1.072 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr12_-_65153055 1.070 GNS
glucosamine (N-acetyl)-6-sulfatase
chr1_-_111991790 1.058 NM_024102
WDR77
WD repeat domain 77
chr16_+_1401936 1.049 GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr16_-_4588379 1.048 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr17_+_49337909 1.043 UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr8_-_104427373 1.039 NM_030780
SLC25A32
solute carrier family 25, member 32
chr12_+_54393876 1.039 NM_006897
HOXC9
homeobox C9
chr17_+_49230896 1.030 NM_000269
NM_198175
NM_001018136
NME1

NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in

NME1-NME2 readthrough
chr9_+_130159383 1.019 NM_014580
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr5_+_110427869 1.017 NM_139281
WDR36
WD repeat domain 36
chr16_+_1401899 1.015 NM_032520
GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr5_+_176730812 1.012 NM_013237
PRELID1
PRELI domain containing 1
chr11_+_66624875 1.012 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr9_-_139137646 1.006 NM_181701
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr5_+_70883132 1.004 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr8_+_104427637 0.995 DCAF13
DDB1 and CUL4 associated factor 13
chr19_+_8509869 0.994 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr1_-_111991859 0.991 WDR77
WD repeat domain 77
chr19_-_48018277 0.984 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_-_6424820 0.982 NM_003685
KHSRP
KH-type splicing regulatory protein
chr1_-_52831817 0.978 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr14_-_20922969 0.977 OSGEP
O-sialoglycoprotein endopeptidase
chr8_-_95274540 0.969 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr7_-_99698993 0.966 MCM7
minichromosome maintenance complex component 7
chr19_+_33685140 0.963 LRP3
low density lipoprotein receptor-related protein 3
chr1_+_154193757 0.955 UBAP2L
ubiquitin associated protein 2-like
chr19_-_6424536 0.952 KHSRP
KH-type splicing regulatory protein
chr8_-_104427268 0.940 SLC25A32
solute carrier family 25, member 32
chr8_-_8750739 0.940 NM_004225
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chrX_+_101380659 0.938 NM_080390
TCEAL2
transcription elongation factor A (SII)-like 2
chr4_-_57301643 0.934 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr6_-_8102753 0.933 NM_001135650
NM_004280
EEF1E1

eukaryotic translation elongation factor 1 epsilon 1

chr10_+_70715883 0.932 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr5_-_131132690 0.931 FNIP1
folliculin interacting protein 1
chr8_-_110657025 0.931 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr8_+_22224786 0.926 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr9_-_103115094 0.925 NM_017746
TEX10
testis expressed 10
chr16_+_11762235 0.925 NM_003498
SNN
stannin
chr10_+_46222647 0.922 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr16_-_1401765 0.922 NM_001001410
C16orf42
chromosome 16 open reading frame 42
chr13_+_113951537 0.921 LAMP1
lysosomal-associated membrane protein 1
chr17_+_49230938 0.916 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough
chr16_+_22308722 0.916 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr7_-_99699030 0.913 MCM7
minichromosome maintenance complex component 7
chr3_-_170626425 0.911 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr6_-_35696359 0.911 NM_001145775
FKBP5
FK506 binding protein 5
chr19_+_8509802 0.909 NM_005968
NM_031203
HNRNPM

heterogeneous nuclear ribonucleoprotein M

chr13_-_50159628 0.905 RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr1_+_44440642 0.902 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr2_-_120980912 0.901 TMEM185B
transmembrane protein 185B
chr5_+_126112847 0.899 LMNB1
lamin B1
chr7_-_27135524 0.899 NM_005522
NM_153620
HOXA1

homeobox A1

chr12_-_76953526 0.897 OSBPL8
oxysterol binding protein-like 8
chr14_+_21510384 0.893 NM_032572
RNASE7
ribonuclease, RNase A family, 7
chr2_+_198364720 0.886 NM_001202485
NM_002157
HSPE1-MOB4
HSPE1
HSPE1-MOB4 readthrough
heat shock 10kDa protein 1 (chaperonin 10)
chr7_-_99698916 0.884 MCM7
minichromosome maintenance complex component 7
chr11_+_33037397 0.884 NM_001077242
DEPDC7
DEP domain containing 7
chr6_-_31763473 0.879 VARS
valyl-tRNA synthetase
chr1_-_28559513 0.875 NM_014280
DNAJC8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr14_-_20922841 0.875 OSGEP
O-sialoglycoprotein endopeptidase
chr2_+_178077421 0.875 NM_194247
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr5_+_126112819 0.872 NM_001198557
LMNB1
lamin B1
chr1_-_26233367 0.871 NM_203399
STMN1
stathmin 1
chr1_-_36184392 0.861 C1orf216
chromosome 1 open reading frame 216
chr20_-_39766522 0.860


chr5_+_126112314 0.853 NM_005573
LMNB1
lamin B1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 6.47e-16 GO:0034641 cellular nitrogen compound metabolic process
1.51 1.05e-15 GO:0006807 nitrogen compound metabolic process
1.55 1.58e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 6.30e-12 GO:0009987 cellular process
1.28 2.10e-11 GO:0044237 cellular metabolic process
1.27 6.71e-11 GO:0044238 primary metabolic process
1.24 1.27e-10 GO:0008152 metabolic process
1.33 2.81e-09 GO:0044260 cellular macromolecule metabolic process
1.51 7.15e-09 GO:0090304 nucleic acid metabolic process
1.54 4.62e-08 GO:0010467 gene expression
1.55 1.71e-07 GO:0016070 RNA metabolic process
1.28 2.76e-07 GO:0043170 macromolecule metabolic process
1.41 5.13e-06 GO:0044249 cellular biosynthetic process
1.40 6.44e-06 GO:0009058 biosynthetic process
1.48 9.85e-06 GO:0044281 small molecule metabolic process
1.83 2.91e-05 GO:0006396 RNA processing
1.56 4.15e-05 GO:0051641 cellular localization
1.33 5.10e-05 GO:0051234 establishment of localization
2.10 8.04e-05 GO:0044419 interspecies interaction between organisms
1.53 9.51e-05 GO:0033036 macromolecule localization
1.33 1.19e-04 GO:0006810 transport
1.68 1.92e-04 GO:0055085 transmembrane transport
1.28 3.21e-04 GO:0051179 localization
1.68 3.64e-04 GO:0046907 intracellular transport
1.80 7.12e-04 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.54 7.13e-04 GO:0051649 establishment of localization in cell
2.80 7.18e-04 GO:0042254 ribosome biogenesis
5.07 1.02e-03 GO:0015682 ferric iron transport
5.07 1.02e-03 GO:0033572 transferrin transport
1.69 1.99e-03 GO:0046483 heterocycle metabolic process
1.80 2.18e-03 GO:0006753 nucleoside phosphate metabolic process
1.80 2.18e-03 GO:0009117 nucleotide metabolic process
1.94 2.58e-03 GO:0044271 cellular nitrogen compound biosynthetic process
2.31 3.10e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.52 3.88e-03 GO:0008104 protein localization
2.26 4.30e-03 GO:0071843 cellular component biogenesis at cellular level
2.13 7.75e-03 GO:0018130 heterocycle biosynthetic process
2.31 8.51e-03 GO:0051169 nuclear transport
1.38 1.19e-02 GO:0009059 macromolecule biosynthetic process
1.74 1.26e-02 GO:0044283 small molecule biosynthetic process
1.38 1.30e-02 GO:0034645 cellular macromolecule biosynthetic process
1.70 1.75e-02 GO:0016071 mRNA metabolic process
2.27 1.78e-02 GO:0006913 nucleocytoplasmic transport
1.79 1.88e-02 GO:0072521 purine-containing compound metabolic process
1.89 2.04e-02 GO:0006520 cellular amino acid metabolic process
1.53 2.05e-02 GO:0045184 establishment of protein localization
1.53 2.70e-02 GO:0015031 protein transport
2.66 3.01e-02 GO:0000041 transition metal ion transport
1.70 3.06e-02 GO:0034613 cellular protein localization
2.39 3.20e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.69 3.79e-02 GO:0070727 cellular macromolecule localization
2.06 4.09e-02 GO:0051186 cofactor metabolic process
2.12 4.49e-02 GO:0000375 RNA splicing, via transesterification reactions

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.64 1.93e-17 GO:0031974 membrane-enclosed lumen
1.17 6.34e-17 GO:0044424 intracellular part
1.16 1.55e-16 GO:0005622 intracellular
1.64 2.46e-16 GO:0070013 intracellular organelle lumen
1.63 3.31e-16 GO:0043233 organelle lumen
1.24 1.83e-15 GO:0005737 cytoplasm
1.21 7.46e-14 GO:0043227 membrane-bounded organelle
1.66 9.34e-14 GO:0031981 nuclear lumen
1.60 1.20e-13 GO:0044428 nuclear part
1.21 1.32e-13 GO:0043231 intracellular membrane-bounded organelle
1.30 8.22e-13 GO:0044422 organelle part
1.31 1.38e-12 GO:0044446 intracellular organelle part
1.18 3.81e-12 GO:0043226 organelle
1.28 4.86e-12 GO:0044444 cytoplasmic part
1.18 5.13e-12 GO:0043229 intracellular organelle
2.20 2.39e-10 GO:0005730 nucleolus
1.65 6.59e-09 GO:0005654 nucleoplasm
1.22 2.00e-06 GO:0005634 nucleus
2.16 8.61e-06 GO:0005773 vacuole
1.73 1.67e-05 GO:0031967 organelle envelope
1.73 1.81e-05 GO:0044451 nucleoplasm part
2.24 2.04e-05 GO:0000323 lytic vacuole
2.24 2.04e-05 GO:0005764 lysosome
1.72 2.10e-05 GO:0031975 envelope
1.87 2.24e-05 GO:0030529 ribonucleoprotein complex
1.36 2.35e-04 GO:0005829 cytosol
1.05 5.00e-04 GO:0044464 cell part
1.05 5.16e-04 GO:0005623 cell
5.85 7.32e-04 GO:0033176 proton-transporting V-type ATPase complex
1.64 1.00e-03 GO:0044429 mitochondrial part
1.43 1.26e-03 GO:0005739 mitochondrion
1.78 1.87e-03 GO:0031966 mitochondrial membrane
1.75 2.10e-03 GO:0005740 mitochondrial envelope
1.23 3.39e-03 GO:0032991 macromolecular complex
1.87 3.41e-03 GO:0019866 organelle inner membrane
2.08 3.75e-03 GO:0016604 nuclear body
2.25 8.79e-03 GO:0044437 vacuolar part
9.75 1.09e-02 GO:0042719 mitochondrial intermembrane space protein transporter complex
1.85 1.33e-02 GO:0005743 mitochondrial inner membrane
3.54 1.72e-02 GO:0016469 proton-transporting two-sector ATPase complex
5.20 2.43e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
5.85 2.86e-02 GO:0030684 preribosome
8.35 3.56e-02 GO:0005666 DNA-directed RNA polymerase III complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 8.68e-09 GO:0005515 protein binding
1.77 3.23e-07 GO:0003723 RNA binding
1.08 1.69e-03 GO:0005488 binding
5.20 3.86e-02 GO:0046961 proton-transporting ATPase activity, rotational mechanism
1.15 4.11e-02 GO:0003824 catalytic activity