Motif ID: ATF5_CREB3.p2

Z-value: 1.276


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF5chr19_+_504323990.319.6e-02Click!
CREB3chr9_+_357326290.058.0e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_58179601 4.041 NM_080672
 PHACTR3
phosphatase and actin regulator 3
chr8_-_110661007 3.246 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
 SYBU




syntabulin (syntaxin-interacting)




chr12_+_132629014 2.794 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_-_216300770 2.595 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr12_+_132628978 2.582 NM_024078
 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_+_50979656 2.497 NM_175063
NM_206538
 C19orf63

chromosome 19 open reading frame 63

chr19_+_50979788 2.114 C19orf63
chromosome 19 open reading frame 63
chr5_+_72861567 2.041 NM_032175
 UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr4_-_89618928 1.848 NM_153757
 NAP1L5
nucleosome assembly protein 1-like 5
chr19_-_9695166 1.741 NM_001008727
 ZNF121
zinc finger protein 121
chr9_-_125027017 1.730 RBM18
RNA binding motif protein 18
chr10_+_103911932 1.592 NM_004741
 NOLC1
nucleolar and coiled-body phosphoprotein 1
chr10_+_35484829 1.513 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
 CREM




cAMP responsive element modulator




chr10_-_97416367 1.491 ALDH18A1
aldehyde dehydrogenase 18 family, member A1
chr8_+_40010986 1.422 NM_020130
 C8orf4
chromosome 8 open reading frame 4
chr17_+_1633754 1.402 WDR81
WD repeat domain 81
chr7_-_25164902 1.358 NM_018947
 CYCS
cytochrome c, somatic
chr11_-_3818736 1.318 NUP98
nucleoporin 98kDa
chr11_+_126138934 1.300 NM_017547
 FOXRED1
FAD-dependent oxidoreductase domain containing 1
chr9_-_140082983 1.291 ANAPC2
anaphase promoting complex subunit 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
3.06 9.62e-04 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
2.96 5.30e-03 GO:0034130 toll-like receptor 1 signaling pathway
2.96 5.30e-03 GO:0034134 toll-like receptor 2 signaling pathway
2.95 1.66e-02 GO:0034138 toll-like receptor 3 signaling pathway
2.86 2.83e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
2.81 8.55e-03 GO:0034142 toll-like receptor 4 signaling pathway
2.73 5.77e-03 GO:0002224 toll-like receptor signaling pathway
2.69 3.10e-02 GO:0008063 Toll signaling pathway
2.61 1.44e-02 GO:0002221 pattern recognition receptor signaling pathway
2.53 2.75e-02 GO:0002758 innate immune response-activating signal transduction
2.47 4.13e-02 GO:0002218 activation of innate immune response
2.13 1.09e-02 GO:0006913 nucleocytoplasmic transport
2.12 3.22e-03 GO:0000375 RNA splicing, via transesterification reactions
2.11 1.48e-02 GO:0051169 nuclear transport
2.08 4.26e-07 GO:0006397 mRNA processing
2.08 9.75e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.08 9.75e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.00 2.96e-04 GO:0008380 RNA splicing
1.96 3.12e-10 GO:0006396 RNA processing
1.94 8.39e-08 GO:0016071 mRNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
5.16 2.03e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.40 3.29e-02 GO:0031201 SNARE complex
2.32 4.05e-03 GO:0016607 nuclear speck
2.08 3.87e-02 GO:0005681 spliceosomal complex
1.64 1.84e-11 GO:0005654 nucleoplasm
1.64 1.60e-03 GO:0030529 ribonucleoprotein complex
1.60 2.07e-14 GO:0031981 nuclear lumen
1.56 1.13e-15 GO:0044428 nuclear part
1.56 4.32e-04 GO:0044451 nucleoplasm part
1.54 3.74e-02 GO:0005730 nucleolus
1.52 1.89e-14 GO:0043233 organelle lumen
1.52 4.61e-14 GO:0070013 intracellular organelle lumen
1.51 2.55e-14 GO:0031974 membrane-enclosed lumen
1.51 2.34e-02 GO:0044431 Golgi apparatus part
1.31 1.16e-16 GO:0005634 nucleus
1.30 5.68e-16 GO:0044422 organelle part
1.30 1.05e-15 GO:0044446 intracellular organelle part
1.28 2.53e-03 GO:0031090 organelle membrane
1.24 1.54e-23 GO:0043227 membrane-bounded organelle
1.24 2.68e-23 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
2.17 1.35e-02 GO:0004386 helicase activity
1.84 2.16e-11 GO:0003723 RNA binding
1.74 6.15e-03 GO:0016887 ATPase activity
1.59 5.72e-05 GO:0016462 pyrophosphatase activity
1.58 7.23e-05 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.58 9.11e-05 GO:0016817 hydrolase activity, acting on acid anhydrides
1.58 1.24e-04 GO:0017111 nucleoside-triphosphatase activity
1.49 1.79e-02 GO:0043565 sequence-specific DNA binding
1.47 6.79e-04 GO:0001071 nucleic acid binding transcription factor activity
1.47 6.79e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 5.39e-11 GO:0000166 nucleotide binding
1.45 3.36e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.44 7.65e-08 GO:0032553 ribonucleotide binding
1.44 7.65e-08 GO:0032555 purine ribonucleotide binding
1.43 8.70e-08 GO:0017076 purine nucleotide binding
1.43 1.03e-05 GO:0005524 ATP binding
1.42 1.48e-05 GO:0032559 adenyl ribonucleotide binding
1.42 1.49e-05 GO:0030554 adenyl nucleotide binding
1.36 1.46e-10 GO:0003676 nucleic acid binding
1.24 2.39e-02 GO:0003677 DNA binding