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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: ATF5_CREB3.p2

Z-value: 1.276

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_+_58179601	4.041	NM_080672	PHACTR3	phosphatase and actin regulator 3
chr8_-_110661007	3.246	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr12_+_132629014	2.794		NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_-_216300770	2.595	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr12_+_132628978	2.582	NM_024078	NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_+_50979656	2.497	NM_175063 NM_206538	C19orf63	chromosome 19 open reading frame 63
chr19_+_50979788	2.114		C19orf63	chromosome 19 open reading frame 63
chr5_+_72861567	2.041	NM_032175	UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr4_-_89618928	1.848	NM_153757	NAP1L5	nucleosome assembly protein 1-like 5
chr19_-_9695166	1.741	NM_001008727	ZNF121	zinc finger protein 121
chr9_-_125027017	1.730		RBM18	RNA binding motif protein 18
chr10_+_103911932	1.592	NM_004741	NOLC1	nucleolar and coiled-body phosphoprotein 1
chr10_+_35484829	1.513	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr10_-_97416367	1.491		ALDH18A1	aldehyde dehydrogenase 18 family, member A1
chr8_+_40010986	1.422	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr17_+_1633754	1.402		WDR81	WD repeat domain 81
chr7_-_25164902	1.358	NM_018947	CYCS	cytochrome c, somatic
chr11_-_3818736	1.318		NUP98	nucleoporin 98kDa
chr11_+_126138934	1.300	NM_017547	FOXRED1	FAD-dependent oxidoreductase domain containing 1
chr9_-_140082983	1.291		ANAPC2	anaphase promoting complex subunit 2
chr4_+_75310852	1.275	NM_001657	AREG	amphiregulin
chr20_+_42086533	1.263		SRSF6	serine/arginine-rich splicing factor 6
chr17_+_40985444	1.252		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr16_+_19078958	1.248		COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr12_-_132628841	1.232	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_-_10588451	1.231	NM_002539	ODC1	ornithine decarboxylase 1
chr4_+_75480628	1.230	NM_001657	AREG	amphiregulin
chr2_-_10588273	1.229		ODC1	ornithine decarboxylase 1
chr19_-_46088021	1.228		OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr11_+_6502607	1.227	NM_012192	FXC1	fracture callus 1 homolog (rat)
chr10_-_97416564	1.197	NM_001017423 NM_002860	ALDH18A1	aldehyde dehydrogenase 18 family, member A1
chr17_+_40985416	1.193	NM_005789 NM_176863	PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr17_+_40985412	1.176		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr9_-_125027080	1.165	NM_033117	RBM18	RNA binding motif protein 18
chr3_+_158288952	1.149	NM_001130156 NM_001130157 NM_001195432 NM_001195433 NM_001195434 NM_022443	MLF1	myeloid leukemia factor 1
chrX_+_24167861	1.144		ZFX	zinc finger protein, X-linked
chr12_+_122150638	1.126	NM_001080825	TMEM120B	transmembrane protein 120B
chrX_+_24167728	1.119	NM_001178086 NM_001178095 NM_001178084 NM_001178085 NM_003410	ZFX	zinc finger protein, X-linked
chr19_-_46088074	1.113		OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr4_+_56261763	1.105
chr6_-_134496833	1.096		SGK1	serum/glucocorticoid regulated kinase 1
chr11_+_126139022	1.092		FOXRED1	FAD-dependent oxidoreductase domain containing 1
chr11_+_126139049	1.090		FOXRED1	FAD-dependent oxidoreductase domain containing 1
chr10_+_119000583	1.079	NM_003054	SLC18A2	solute carrier family 18 (vesicular monoamine), member 2
chr4_+_72052354	1.073	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr7_+_44646189	1.067		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_19078916	1.062	NM_016138	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr7_+_44646197	1.057		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_44646168	1.037		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr17_+_40985434	1.015		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr5_-_1524022	1.007	NM_024830	LPCAT1	lysophosphatidylcholine acyltransferase 1
chr16_+_19079220	0.976	NM_001190983	COQ7	coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_134497069	0.970	NM_001143678	SGK1	serum/glucocorticoid regulated kinase 1
chr3_-_195808980	0.960		TFRC	transferrin receptor (p90, CD71)
chr21_-_34915124	0.959	NM_001136005 NM_001136006	GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr2_-_157189040	0.943	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr6_+_64282449	0.933		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr17_+_46018888	0.922	NM_018129	PNPO	pyridoxamine 5'-phosphate oxidase
chr17_+_1619816	0.919	NM_001163673 NM_152348	WDR81	WD repeat domain 81
chr11_-_111749810	0.910		FDXACB1	ferredoxin-fold anticodon binding domain containing 1
chr4_-_79860369	0.909	NM_001040202	PAQR3	progestin and adipoQ receptor family member III
chr7_+_6144504	0.908	NM_032172	USP42	ubiquitin specific peptidase 42
chr4_-_23891608	0.908	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_-_60780404	0.905	NM_018014 NM_022893 NM_138559	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr11_-_118927815	0.902		HYOU1	hypoxia up-regulated 1
chr20_-_56284945	0.895	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr21_-_43430448	0.886	NM_001098402 NM_001098403 NM_020727	ZNF295	zinc finger protein 295
chr7_-_25164869	0.881		CYCS	cytochrome c, somatic
chr12_+_66583004	0.867		IRAK3	interleukin-1 receptor-associated kinase 3
chr19_+_10362886	0.867		MRPL4	mitochondrial ribosomal protein L4
chr9_+_125027152	0.865		MRRF	mitochondrial ribosome recycling factor
chr10_+_99079017	0.865	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr13_-_45563554	0.864	NM_012345	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1
chr16_-_68057098	0.859		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr18_-_267987	0.855	NM_005131	THOC1	THO complex 1
chr22_-_29196452	0.836		XBP1	X-box binding protein 1
chr17_+_38171613	0.832	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr17_+_27071008	0.831	NM_004295	TRAF4	TNF receptor-associated factor 4
chr11_-_3818971	0.829	NM_005387 NM_016320 NM_139131 NM_139132	NUP98	nucleoporin 98kDa
chr1_-_91487543	0.828		ZNF644	zinc finger protein 644
chr12_+_82752275	0.825	NM_032230	C12orf26	chromosome 12 open reading frame 26
chr17_+_40985425	0.819		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr8_-_104427319	0.815		SLC25A32	solute carrier family 25, member 32
chr20_+_18794369	0.813	NM_178483	C20orf79	chromosome 20 open reading frame 79
chr7_-_156685621	0.812		LMBR1	limb region 1 homolog (mouse)
chr17_-_39165343	0.808	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr7_+_30174343	0.807	NM_152793	C7orf41	chromosome 7 open reading frame 41
chr7_-_8301767	0.804	NM_001136020	ICA1	islet cell autoantigen 1, 69kDa
chr12_+_66582914	0.795	NM_001142523 NM_007199	IRAK3	interleukin-1 receptor-associated kinase 3
chr12_+_90103470	0.783		LOC338758	uncharacterized LOC338758
chr4_-_156297944	0.780		MAP9	microtubule-associated protein 9
chr16_-_68057120	0.776		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr1_-_53704121	0.772	NM_002370	MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)
chr6_-_108395939	0.771	NM_014028	OSTM1	osteopetrosis associated transmembrane protein 1
chr12_+_27397077	0.767	NM_015000	STK38L	serine/threonine kinase 38 like
chr9_+_80850938	0.765	NM_001098802 NM_032171	CEP78	centrosomal protein 78kDa
chr11_-_116968986	0.762	NM_025164	SIK3	SIK family kinase 3
chr11_-_77184549	0.761	NM_001128620 NM_002576	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr17_-_72968750	0.758
chr8_-_10697382	0.758		PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1
chr7_+_116660263	0.756		ST7	suppression of tumorigenicity 7
chr7_+_129008044	0.754		AHCYL2	adenosylhomocysteinase-like 2
chr11_+_113930430	0.751	NM_006006	ZBTB16	zinc finger and BTB domain containing 16
chr1_+_948846	0.750	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr7_+_44646220	0.748		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr11_-_67276101	0.744	NM_005851	CDK2AP2	cyclin-dependent kinase 2 associated protein 2
chr3_-_119182423	0.742	NM_018266	TMEM39A	transmembrane protein 39A
chr20_+_35201948	0.738	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr12_-_94853453	0.733		CCDC41	coiled-coil domain containing 41
chr19_+_49122762	0.728		SPHK2	sphingosine kinase 2
chr11_+_113930296	0.726		ZBTB16	zinc finger and BTB domain containing 16
chr18_+_7567313	0.723	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr3_+_170075449	0.723	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr22_-_29196537	0.723	NM_001079539 NM_005080	XBP1	X-box binding protein 1
chr7_+_107531585	0.720	NM_000108	DLD	dihydrolipoamide dehydrogenase
chr7_+_129007942	0.716	NM_001130723	AHCYL2	adenosylhomocysteinase-like 2
chr3_-_195808934	0.712		TFRC	transferrin receptor (p90, CD71)
chr19_+_49122789	0.710	NM_001204159	SPHK2	sphingosine kinase 2
chr12_+_56660913	0.702		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr19_-_46088084	0.697	NM_001017989 NM_025136	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr4_-_54232007	0.696	NM_152540	SCFD2	sec1 family domain containing 2
chr20_+_33292117	0.695	NM_021202	TP53INP2	tumor protein p53 inducible nuclear protein 2
chr5_+_50679239	0.693		ISL1	ISL LIM homeobox 1
chr6_+_41888993	0.692		BYSL	bystin-like
chr3_+_93698959	0.690	NM_001174150 NM_001174151 NM_144996 NM_182896	ARL13B	ADP-ribosylation factor-like 13B
chr10_+_22634373	0.680	NM_001253854 NM_001253855 NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr20_+_18488167	0.679	NM_006363 NM_032985 NM_032986 NM_001172746	SEC23B	Sec23 homolog B (S. cerevisiae)
chr6_+_41888964	0.677	NM_004053	BYSL	bystin-like
chr7_+_6144589	0.675		USP42	ubiquitin specific peptidase 42
chr3_-_195808958	0.675	NM_003234	TFRC	transferrin receptor (p90, CD71)
chr1_+_87794150	0.673	NM_006769	LMO4	LIM domain only 4
chr11_-_3818706	0.672		NUP98	nucleoporin 98kDa
chr3_-_154042204	0.668	NM_001114397 NM_020865	DHX36	DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr3_-_185655776	0.666		TRA2B	transformer 2 beta homolog (Drosophila)
chr19_+_3762671	0.664		MRPL54	mitochondrial ribosomal protein L54
chr3_+_186739643	0.662	NM_003032	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_64281910	0.659	NM_003463	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr3_-_186288331	0.658	NM_001134415	TBCCD1	TBCC domain containing 1
chr6_-_108395854	0.650		OSTM1	osteopetrosis associated transmembrane protein 1
chr12_+_56660724	0.649		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr3_+_99536667	0.648	NM_032359	C3orf26	chromosome 3 open reading frame 26
chr7_-_8301681	0.647	NM_022307	ICA1	islet cell autoantigen 1, 69kDa
chr12_+_56661026	0.647	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr3_-_195808997	0.640	NM_001128148	TFRC	transferrin receptor (p90, CD71)
chr6_-_108395918	0.637		OSTM1	osteopetrosis associated transmembrane protein 1
chr16_+_70148213	0.637		PDPR	pyruvate dehydrogenase phosphatase regulatory subunit
chr19_+_3762650	0.635	NM_172251	MRPL54	mitochondrial ribosomal protein L54
chr14_-_76448091	0.635	NM_003239	TGFB3	transforming growth factor, beta 3
chr18_+_20513277	0.634	NM_002894	RBBP8	retinoblastoma binding protein 8
chr19_-_44100127	0.632	NM_001007561	IRGQ	immunity-related GTPase family, Q
chr16_+_475605	0.631		RAB11FIP3	RAB11 family interacting protein 3 (class II)
chrX_+_44732402	0.630	NM_021140	KDM6A	lysine (K)-specific demethylase 6A
chr7_+_22766765	0.628	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr17_-_47785527	0.626		SLC35B1	solute carrier family 35, member B1
chr17_-_47785132	0.625		SLC35B1	solute carrier family 35, member B1
chr8_+_64081187	0.623		YTHDF3	YTH domain family, member 3
chr9_-_70490123	0.622		CBWD3	COBW domain containing 3
chr8_-_74791078	0.620		UBE2W	ubiquitin-conjugating enzyme E2W (putative)
chr1_-_31769599	0.619	NM_004814	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chrX_-_13956644	0.619	NM_001001994	GPM6B	glycoprotein M6B
chr17_-_8151353	0.618		CTC1	CTS telomere maintenance complex component 1
chr6_-_31846751	0.618		SLC44A4	solute carrier family 44, member 4
chr12_+_59989847	0.617		SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr20_+_42086468	0.615	NM_006275	SRSF6	serine/arginine-rich splicing factor 6
chr1_+_231114839	0.613
chr17_+_2497233	0.613		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr8_-_29207795	0.611	NM_001394	DUSP4	dual specificity phosphatase 4
chr12_+_56660548	0.610	NM_144576	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr19_-_14316980	0.608	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr6_+_43211221	0.606	NM_032538	TTBK1	tau tubulin kinase 1
chr16_+_475629	0.604	NM_014700	RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr6_+_39760148	0.604	NM_001201427	DAAM2	dishevelled associated activator of morphogenesis 2
chrX_-_7895424	0.603	NM_004650	PNPLA4	patatin-like phospholipase domain containing 4
chr17_-_47785270	0.602	NM_005827	SLC35B1	solute carrier family 35, member B1
chr22_+_21996591	0.598		SDF2L1	stromal cell-derived factor 2-like 1
chr9_-_127703294	0.597	NM_002077	GOLGA1	golgin A1
chr9_+_91933384	0.596	NM_024077	SECISBP2	SECIS binding protein 2
chr1_+_218518675	0.595	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chr3_-_185655648	0.595		TRA2B	transformer 2 beta homolog (Drosophila)
chr1_-_38273823	0.595		YRDC	yrdC domain containing (E. coli)
chr12_+_7282963	0.595	NM_014718	CLSTN3	calsyntenin 3
chr19_+_49375677	0.587		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr5_+_148206155	0.586	NM_000024	ADRB2	adrenergic, beta-2-, receptor, surface
chr11_-_126138824	0.586	NM_001177842 NM_003139	SRPR	signal recognition particle receptor (docking protein)
chr8_+_17104384	0.586	NM_001145152 NM_152415	VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr22_+_21996572	0.585		SDF2L1	stromal cell-derived factor 2-like 1
chr2_-_9563584	0.585		ITGB1BP1	integrin beta 1 binding protein 1
chr17_-_72968790	0.585	NM_030630	C17orf28	chromosome 17 open reading frame 28
chr3_+_186288445	0.583	NM_016306	DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11
chr11_-_126138736	0.582		SRPR	signal recognition particle receptor (docking protein)
chr7_+_22767101	0.580		IL6	interleukin 6 (interferon, beta 2)
chr19_+_49375679	0.578		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr5_+_50678957	0.578	NM_002202	ISL1	ISL LIM homeobox 1
chr8_-_71581354	0.576		LACTB2	lactamase, beta 2
chr8_-_74791072	0.575		UBE2W	ubiquitin-conjugating enzyme E2W (putative)
chr8_+_123793894	0.574	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr19_-_18314731	0.573	NM_002866	RAB3A	RAB3A, member RAS oncogene family
chr1_-_11120001	0.571		SRM	spermidine synthase
chr11_+_65337923	0.569	NM_006396	SSSCA1	Sjogren syndrome/scleroderma autoantigen 1
chr3_-_185655806	0.567		TRA2B	transformer 2 beta homolog (Drosophila)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.39	2.54e-17	GO:0044260	cellular macromolecule metabolic process
1.56	2.33e-14	GO:0090304	nucleic acid metabolic process
1.48	2.74e-14	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	6.80e-14	GO:0044237	cellular metabolic process
1.60	2.60e-13	GO:0010467	gene expression
1.32	2.81e-13	GO:0043170	macromolecule metabolic process
1.41	6.51e-12	GO:0034641	cellular nitrogen compound metabolic process
1.59	7.01e-12	GO:0016070	RNA metabolic process
1.38	1.10e-10	GO:0006807	nitrogen compound metabolic process
1.96	3.12e-10	GO:0006396	RNA processing
1.23	5.46e-10	GO:0044238	primary metabolic process
1.21	1.79e-09	GO:0008152	metabolic process
1.68	2.26e-09	GO:0051649	establishment of localization in cell
1.12	5.59e-09	GO:0009987	cellular process
1.61	1.69e-08	GO:0051641	cellular localization
1.94	8.39e-08	GO:0016071	mRNA metabolic process
1.74	3.31e-07	GO:0046907	intracellular transport
2.08	4.26e-07	GO:0006397	mRNA processing
1.66	3.19e-06	GO:0015031	protein transport
1.64	5.75e-06	GO:0045184	establishment of protein localization
1.51	7.19e-06	GO:0033036	macromolecule localization
1.33	6.81e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.33	7.00e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.52	1.10e-04	GO:0008104	protein localization
1.30	1.35e-04	GO:0009889	regulation of biosynthetic process
1.40	1.96e-04	GO:0009059	macromolecule biosynthetic process
1.31	2.28e-04	GO:0010468	regulation of gene expression
1.30	2.54e-04	GO:0031326	regulation of cellular biosynthetic process
1.39	2.70e-04	GO:0034645	cellular macromolecule biosynthetic process
1.57	2.76e-04	GO:0006351	transcription, DNA-dependent
2.00	2.96e-04	GO:0008380	RNA splicing
1.33	3.39e-04	GO:0051252	regulation of RNA metabolic process
1.30	4.86e-04	GO:0044267	cellular protein metabolic process
1.24	5.74e-04	GO:0031323	regulation of cellular metabolic process
1.28	6.75e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.32	9.49e-04	GO:0006355	regulation of transcription, DNA-dependent
3.06	9.62e-04	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.25	1.03e-03	GO:0060255	regulation of macromolecule metabolic process
1.27	2.88e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.12	3.22e-03	GO:0000375	RNA splicing, via transesterification reactions
2.96	5.30e-03	GO:0034130	toll-like receptor 1 signaling pathway
2.96	5.30e-03	GO:0034134	toll-like receptor 2 signaling pathway
1.66	5.53e-03	GO:0044265	cellular macromolecule catabolic process
2.73	5.77e-03	GO:0002224	toll-like receptor signaling pathway
1.22	6.29e-03	GO:0080090	regulation of primary metabolic process
2.81	8.55e-03	GO:0034142	toll-like receptor 4 signaling pathway
1.28	9.38e-03	GO:0044249	cellular biosynthetic process
2.08	9.75e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.08	9.75e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.27	1.09e-02	GO:0009058	biosynthetic process
2.13	1.09e-02	GO:0006913	nucleocytoplasmic transport
1.20	1.14e-02	GO:0019222	regulation of metabolic process
2.61	1.44e-02	GO:0002221	pattern recognition receptor signaling pathway
2.11	1.48e-02	GO:0051169	nuclear transport
1.79	1.58e-02	GO:0070647	protein modification by small protein conjugation or removal
2.95	1.66e-02	GO:0034138	toll-like receptor 3 signaling pathway
1.44	1.92e-02	GO:0032774	RNA biosynthetic process
1.82	2.48e-02	GO:0051329	interphase of mitotic cell cycle
2.53	2.75e-02	GO:0002758	innate immune response-activating signal transduction
1.50	2.77e-02	GO:0016192	vesicle-mediated transport
2.86	2.83e-02	GO:0002756	MyD88-independent toll-like receptor signaling pathway
2.69	3.10e-02	GO:0008063	Toll signaling pathway
2.47	4.13e-02	GO:0002218	activation of innate immune response
1.79	4.22e-02	GO:0051325	interphase
1.76	4.77e-02	GO:0019941	modification-dependent protein catabolic process
1.46	4.85e-02	GO:0033554	cellular response to stress

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.24	1.54e-23	GO:0043227	membrane-bounded organelle
1.17	1.85e-23	GO:0044424	intracellular part
1.24	2.68e-23	GO:0043231	intracellular membrane-bounded organelle
1.17	3.65e-23	GO:0005622	intracellular
1.20	1.27e-20	GO:0043226	organelle
1.20	1.51e-20	GO:0043229	intracellular organelle
1.31	1.16e-16	GO:0005634	nucleus
1.30	5.68e-16	GO:0044422	organelle part
1.30	1.05e-15	GO:0044446	intracellular organelle part
1.56	1.13e-15	GO:0044428	nuclear part
1.52	1.89e-14	GO:0043233	organelle lumen
1.60	2.07e-14	GO:0031981	nuclear lumen
1.51	2.55e-14	GO:0031974	membrane-enclosed lumen
1.52	4.61e-14	GO:0070013	intracellular organelle lumen
1.64	1.84e-11	GO:0005654	nucleoplasm
1.16	5.26e-09	GO:0005737	cytoplasm
1.24	8.80e-05	GO:0032991	macromolecular complex
1.16	4.18e-04	GO:0044444	cytoplasmic part
1.56	4.32e-04	GO:0044451	nucleoplasm part
1.64	1.60e-03	GO:0030529	ribonucleoprotein complex
5.16	2.03e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.28	2.53e-03	GO:0031090	organelle membrane
2.32	4.05e-03	GO:0016607	nuclear speck
1.22	8.86e-03	GO:0043234	protein complex
1.51	2.34e-02	GO:0044431	Golgi apparatus part
4.40	3.29e-02	GO:0031201	SNARE complex
1.54	3.74e-02	GO:0005730	nucleolus
2.08	3.87e-02	GO:0005681	spliceosomal complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	1.51e-12	GO:0005515	protein binding
1.84	2.16e-11	GO:0003723	RNA binding
1.12	3.53e-11	GO:0005488	binding
1.45	5.39e-11	GO:0000166	nucleotide binding
1.36	1.46e-10	GO:0003676	nucleic acid binding
1.45	3.36e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.44	7.65e-08	GO:0032553	ribonucleotide binding
1.44	7.65e-08	GO:0032555	purine ribonucleotide binding
1.43	8.70e-08	GO:0017076	purine nucleotide binding
1.43	1.03e-05	GO:0005524	ATP binding
1.42	1.48e-05	GO:0032559	adenyl ribonucleotide binding
1.42	1.49e-05	GO:0030554	adenyl nucleotide binding
1.59	5.72e-05	GO:0016462	pyrophosphatase activity
1.58	7.23e-05	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.58	9.11e-05	GO:0016817	hydrolase activity, acting on acid anhydrides
1.58	1.24e-04	GO:0017111	nucleoside-triphosphatase activity
1.47	6.79e-04	GO:0001071	nucleic acid binding transcription factor activity
1.47	6.79e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.74	6.15e-03	GO:0016887	ATPase activity
2.17	1.35e-02	GO:0004386	helicase activity
1.49	1.79e-02	GO:0043565	sequence-specific DNA binding
1.24	2.39e-02	GO:0003677	DNA binding