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Motif ID: ATF6.p2

Z-value: 1.195

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_2018703	2.268		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr1_+_183605207	2.171	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_+_85527992	2.123	NM_145172	WDR63	WD repeat domain 63
chr7_-_73184535	2.119	NM_001306	CLDN3	claudin 3
chr16_-_54320367	2.073	NM_024336	IRX3	iroquois homeobox 3
chr3_-_197686837	2.070	NM_032263	IQCG	IQ motif containing G
chr3_-_187463227	1.845		BCL6	B-cell CLL/lymphoma 6
chrY_+_2803409	1.691	NM_001145275 NM_003411	ZFY	zinc finger protein, Y-linked
chr3_-_187463474	1.640	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr14_+_45431333	1.556	NM_015091	FAM179B	family with sequence similarity 179, member B
chrY_+_2803111	1.534	NM_001145276	ZFY	zinc finger protein, Y-linked
chr16_-_54320328	1.454		IRX3	iroquois homeobox 3
chr22_+_35777051	1.449	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr14_+_74486049	1.393	NM_025057	C14orf45	chromosome 14 open reading frame 45
chr16_-_75529289	1.382
chr22_+_35777087	1.326		HMOX1	heme oxygenase (decycling) 1
chr10_+_22634373	1.250	NM_001253854 NM_001253855 NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr20_-_25038501	1.204	NM_001252675 NM_001252677 NM_032501	ACSS1	acyl-CoA synthetase short-chain family member 1
chr1_+_87794150	1.201	NM_006769	LMO4	LIM domain only 4
chr3_+_39149151	1.184	NM_001105513 NM_145755	TTC21A	tetratricopeptide repeat domain 21A
chr16_-_66959418	1.180	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr21_-_43916298	1.138	NM_080860	RSPH1	radial spoke head 1 homolog (Chlamydomonas)
chr10_+_99079017	1.116	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr12_-_112450914	1.053	NM_001193453 NM_001193531 NM_138341	LOC728543 TMEM116	uncharacterized LOC728543 transmembrane protein 116
chr1_+_9599520	1.049	NM_032315	SLC25A33	solute carrier family 25, member 33
chr6_-_31846751	1.040		SLC44A4	solute carrier family 44, member 4
chr1_+_9599546	1.023		SLC25A33	solute carrier family 25, member 33
chr15_-_50978921	1.000		TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr5_+_78531848	0.989	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr11_+_67159421	0.974	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chrX_+_30671456	0.966	NM_000167 NM_001128127 NM_001205019 NM_203391	GK	glycerol kinase
chr6_-_31846816	0.961	NM_001178044 NM_025257	SLC44A4	solute carrier family 44, member 4
chr3_+_129159150	0.936		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129158949	0.936	NM_018262 NM_052985 NM_052989 NM_052990	IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr14_-_45431090	0.932		KLHL28	kelch-like 28 (Drosophila)
chr9_+_136325086	0.931	NM_001135775 NM_001242369 NM_001242370 NM_017586	C9orf7	chromosome 9 open reading frame 7
chr3_+_129159075	0.929		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159138	0.929		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_129159089	0.920		IFT122	intraflagellar transport 122 homolog (Chlamydomonas)
chrX_+_30671537	0.908		GK	glycerol kinase
chr4_+_166299942	0.906	NM_001873	CPE	carboxypeptidase E
chr11_-_2019070	0.904		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr3_-_119182423	0.903	NM_018266	TMEM39A	transmembrane protein 39A
chr11_+_7535000	0.883	NM_003621	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_+_219745243	0.873	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr1_+_87794548	0.870		LMO4	LIM domain only 4
chr5_+_172483285	0.861	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr10_-_99094427	0.859	NM_012083	FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr12_+_56660913	0.835		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr1_+_183774214	0.834		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr15_-_50978726	0.829		TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr11_+_7535213	0.825		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_+_56212381	0.820	NM_024592	SRD5A3	steroid 5 alpha-reductase 3
chr8_-_110661007	0.818	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr2_-_242212198	0.814		HDLBP	high density lipoprotein binding protein
chr2_+_97426571	0.811	NM_020184	CNNM4	cyclin M4
chr20_+_33146500	0.810	NM_032514	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha
chr5_-_139944045	0.810	NM_006051 NM_133172 NM_133173 NM_133174	APBB3	amyloid beta (A4) precursor protein-binding, family B, member 3
chr12_+_56660724	0.808		COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr6_+_159070994	0.805	NM_001009991 NM_001242384 NM_001242394 NM_001242395	SYTL3	synaptotagmin-like 3
chr11_+_46299161	0.799	NM_052854	CREB3L1	cAMP responsive element binding protein 3-like 1
chr11_-_62476976	0.798		BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr21_-_38444814	0.797	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr6_-_31846766	0.795		SLC44A4	solute carrier family 44, member 4
chr1_+_222791151	0.793	NM_198551	MIA3	melanoma inhibitory activity family, member 3
chr12_+_56661026	0.788	NM_001099337	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr14_-_38064440	0.776	NM_004496	FOXA1	forkhead box A1
chr12_+_56660548	0.772	NM_144576	COQ10A	coenzyme Q10 homolog A (S. cerevisiae)
chr16_+_22217369	0.764	NM_013302	EEF2K	eukaryotic elongation factor-2 kinase
chr4_+_85504056	0.761	NM_001263	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr19_-_5340700	0.754	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr1_+_151483861	0.746	NM_020770	CGN	cingulin
chr10_-_62703822	0.745	NM_001242359 NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr11_+_67776016	0.741	NM_001161473	ALDH3B1	aldehyde dehydrogenase 3 family, member B1
chr4_+_37455551	0.737	NM_001104629	C4orf19	chromosome 4 open reading frame 19
chr9_+_34458810	0.736	NM_012144	DNAI1	dynein, axonemal, intermediate chain 1
chr4_-_39640461	0.736	NM_174921	C4orf34	chromosome 4 open reading frame 34
chr22_-_31503484	0.736	NM_080430	SELM	selenoprotein M
chr13_-_49107250	0.735	NM_001268	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr7_+_116593554	0.735		ST7	suppression of tumorigenicity 7
chr3_-_107941168	0.734	NM_018010	IFT57	intraflagellar transport 57 homolog (Chlamydomonas)
chr3_-_190580464	0.730	NM_001146686	GMNC	geminin coiled-coil domain containing
chr10_+_99496847	0.730	NM_001002262 NM_001174119 NM_001174120 NM_001174121 NM_001174122 NM_144588	ZFYVE27	zinc finger, FYVE domain containing 27
chr11_-_119234859	0.728	NM_171997	USP2	ubiquitin specific peptidase 2
chr10_+_99496891	0.728		ZFYVE27	zinc finger, FYVE domain containing 27
chr12_+_112451261	0.719		ERP29	endoplasmic reticulum protein 29
chr10_-_50122279	0.718	NM_001006939	LRRC18	leucine rich repeat containing 18
chr17_+_53342356	0.707		HLF	hepatic leukemia factor
chr20_+_3451727	0.701		ATRN	attractin
chr13_-_49107357	0.693		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_+_100211554	0.678		TMEM45A	transmembrane protein 45A
chr1_-_204329043	0.671	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr12_+_112451151	0.668	NM_001034025 NM_006817	ERP29	endoplasmic reticulum protein 29
chr6_+_33168602	0.660	NM_001077516 NM_006979	SLC39A7	solute carrier family 39 (zinc transporter), member 7
chr9_-_90589593	0.659	NM_001039803 NM_001170639 NM_001170640 NM_012119 NM_178432	CDK20	cyclin-dependent kinase 20
chr3_-_122512526	0.654	NM_024610	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr5_+_56469655	0.653	NM_001203246 NM_022913	GPBP1	GC-rich promoter binding protein 1
chrX_+_30671602	0.652		GK	glycerol kinase
chr19_-_36705556	0.651	NM_152477	ZNF565	zinc finger protein 565
chr1_+_110527327	0.641	NM_001242673 NM_006621	AHCYL1	adenosylhomocysteinase-like 1
chr1_+_6640094	0.640		ZBTB48	zinc finger and BTB domain containing 48
chr17_+_53342320	0.639	NM_002126	HLF	hepatic leukemia factor
chr3_+_100211408	0.638	NM_018004	TMEM45A	transmembrane protein 45A
chr4_+_52917440	0.631	NM_145263	SPATA18	spermatogenesis associated 18 homolog (rat)
chr11_-_66445218	0.626	NM_031492	RBM4B	RNA binding motif protein 4B
chr17_+_79935493	0.625		ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr10_+_94833646	0.625	NM_000783	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1
chrX_+_55744049	0.624	NM_006064 NM_016656	RRAGB	Ras-related GTP binding B
chr17_+_42977141	0.623	NM_213607	CCDC103	coiled-coil domain containing 103
chr12_+_6898705	0.621		CD4	CD4 molecule
chrX_-_100914816	0.611	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr6_+_64345709	0.611		PHF3	PHD finger protein 3
chr20_-_2821245	0.608	NM_022760	FAM113A	family with sequence similarity 113, member A
chr5_+_56469851	0.603		GPBP1	GC-rich promoter binding protein 1
chr13_-_49107185	0.601		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr10_+_99496938	0.601		ZFYVE27	zinc finger, FYVE domain containing 27
chr16_-_29910340	0.601	NM_001114099 NM_001114100 NM_001243332 NM_001243333 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr16_+_53164784	0.600		CHD9	chromodomain helicase DNA binding protein 9
chr19_+_10527448	0.600	NM_001243121	PDE4A	phosphodiesterase 4A, cAMP-specific
chr14_-_61190458	0.599	NM_017420	SIX4	SIX homeobox 4
chr17_+_6555037	0.597	NM_001105520	C17orf100	chromosome 17 open reading frame 100
chr17_-_49337370	0.594	NM_017643	MBTD1	mbt domain containing 1
chr13_-_101327102	0.593	NM_001079669 NM_032813	TMTC4	transmembrane and tetratricopeptide repeat containing 4
chr12_+_6898605	0.592	NM_000616 NM_001195014 NM_001195015 NM_001195016 NM_001195017	CD4	CD4 molecule
chr2_-_25194772	0.581	NM_001198559 NM_016544	DNAJC27	DnaJ (Hsp40) homolog, subfamily C, member 27
chr1_+_87794576	0.580		LMO4	LIM domain only 4
chr21_-_38445389	0.578	NM_153682	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_157189040	0.576	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr17_-_57184116	0.575		TRIM37	tripartite motif containing 37
chr11_-_67272773	0.564	NM_001130848 NM_004910	PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1
chr7_+_116660263	0.562		ST7	suppression of tumorigenicity 7
chr13_-_101327027	0.562		TMTC4	transmembrane and tetratricopeptide repeat containing 4
chr5_+_99871234	0.561		FAM174A	family with sequence similarity 174, member A
chr7_+_23719743	0.560	NM_001127364 NM_001127365 NM_199136	C7orf46	chromosome 7 open reading frame 46
chr5_-_139943829	0.556		APBB3	amyloid beta (A4) precursor protein-binding, family B, member 3
chr16_-_75528925	0.553	NM_021615	CHST6	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
chr6_-_30043547	0.548	NM_170769 NM_025236	RNF39	ring finger protein 39
chr15_-_72668184	0.548		HEXA	hexosaminidase A (alpha polypeptide)
chr9_-_84304378	0.547		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr15_+_44084039	0.543	NM_001018108 NM_001199875 NM_001199876	SERF2	small EDRK-rich factor 2
chr1_+_109289266	0.543	NM_007269	STXBP3	syntaxin binding protein 3
chr17_-_7197896	0.540		YBX2	Y box binding protein 2
chr11_+_126081618	0.537	NM_024556	FAM118B	family with sequence similarity 118, member B
chr12_-_14720790	0.536	NM_024829	PLBD1	phospholipase B domain containing 1
chr1_+_26496382	0.535	NM_015871	ZNF593	zinc finger protein 593
chr7_+_102073953	0.532	NM_001126340 NM_032831	ORAI2	ORAI calcium release-activated calcium modulator 2
chr2_+_11052062	0.531	NM_002236	KCNF1	potassium voltage-gated channel, subfamily F, member 1
chr2_-_97535669	0.529	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr18_+_72922725	0.527	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr19_+_3708358	0.527		TJP3	tight junction protein 3 (zona occludens 3)
chr12_+_11802905	0.525		ETV6	ets variant 6
chr21_+_38445562	0.521	NM_001001894	TTC3	tetratricopeptide repeat domain 3
chr6_+_127587984	0.519		RNF146	ring finger protein 146
chr16_+_4385141	0.518		GLIS2	GLIS family zinc finger 2
chr3_+_197687070	0.514	NM_001136049 NM_033029	LMLN	leishmanolysin-like (metallopeptidase M8 family)
chr19_-_46088021	0.514		OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr14_-_39901619	0.513	NM_203301	FBXO33	F-box protein 33
chr7_+_27225009	0.510		HOXA11-AS1	HOXA11 antisense RNA 1 (non-protein coding)
chr14_+_74551655	0.510	NM_001024674	LIN52	lin-52 homolog (C. elegans)
chr5_+_99871023	0.509	NM_198507	FAM174A	family with sequence similarity 174, member A
chr12_+_11802642	0.506		ETV6	ets variant 6
chr4_-_18023358	0.505	NM_001166139 NM_153686	LCORL	ligand dependent nuclear receptor corepressor-like
chr4_+_56212456	0.504		SRD5A3	steroid 5 alpha-reductase 3
chr3_+_125688027	0.503	NM_001012337	ROPN1B	rhophilin associated tail protein 1B
chr1_+_233749749	0.503	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr3_+_49027770	0.503		P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr9_-_79520878	0.502	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr14_-_77494974	0.501	NM_024496	IRF2BPL	interferon regulatory factor 2 binding protein-like
chr9_-_90589360	0.497		CDK20	cyclin-dependent kinase 20
chr17_+_41132587	0.497		RUNDC1	RUN domain containing 1
chr1_+_84767288	0.496	NM_001134663	SAMD13	sterile alpha motif domain containing 13
chr3_-_12200339	0.495		TIMP4	TIMP metallopeptidase inhibitor 4
chr7_-_8301767	0.494	NM_001136020	ICA1	islet cell autoantigen 1, 69kDa
chr19_+_6772801	0.492
chr1_+_14026685	0.492	NM_001135610	PRDM2	PR domain containing 2, with ZNF domain
chr19_-_7553867	0.490	NM_080662	PEX11G	peroxisomal biogenesis factor 11 gamma
chr19_+_14544216	0.489		PKN1	protein kinase N1
chr19_+_3094266	0.487	NM_002067	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr17_+_41132581	0.487	NM_173079	RUNDC1	RUN domain containing 1
chr17_-_7197866	0.482	NM_015982	YBX2	Y box binding protein 2
chr17_-_46688279	0.482		HOXB7	homeobox B7
chr22_-_37172113	0.478	NM_001177701 NM_006860	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)
chr15_+_43809805	0.478	NM_002373	MAP1A	microtubule-associated protein 1A
chr1_+_6640047	0.478	NM_005341	ZBTB48	zinc finger and BTB domain containing 48
chr20_-_2821120	0.476		FAM113A	family with sequence similarity 113, member A
chr11_+_118938530	0.474		VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr17_+_7761310	0.473		CYB5D1	cytochrome b5 domain containing 1
chr2_-_211035913	0.471	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr9_+_6757919	0.468		KDM4C	lysine (K)-specific demethylase 4C
chr17_-_7197811	0.467		YBX2	Y box binding protein 2
chr6_-_106773607	0.466	NM_004849	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr1_-_166845469	0.466		TADA1	transcriptional adaptor 1
chr16_-_88923233	0.463		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr16_+_475605	0.461		RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr6_-_32551993	0.461		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr1_+_15250578	0.460	NM_001018000	KAZN	kazrin, periplakin interacting protein
chr3_+_113251217	0.459	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr8_+_27491384	0.458		SCARA3	scavenger receptor class A, member 3
chr22_-_39268214	0.455		CBX6	chromobox homolog 6
chr5_-_122759003	0.455	NM_001166226 NM_153223	CEP120	centrosomal protein 120kDa

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.35	1.68e-07	GO:0044260	cellular macromolecule metabolic process
1.30	9.98e-07	GO:0043170	macromolecule metabolic process
1.71	2.51e-05	GO:0008104	protein localization
1.78	6.44e-05	GO:0015031	protein transport
1.75	1.54e-04	GO:0045184	establishment of protein localization
1.58	3.21e-04	GO:0033036	macromolecule localization
1.21	7.98e-04	GO:0044237	cellular metabolic process
1.18	3.16e-03	GO:0008152	metabolic process
1.38	4.64e-03	GO:0090304	nucleic acid metabolic process
2.74	8.47e-03	GO:0048193	Golgi vesicle transport
1.18	1.15e-02	GO:0044238	primary metabolic process
1.50	1.50e-02	GO:0051641	cellular localization
1.65	1.57e-02	GO:0046907	intracellular transport
1.98	1.72e-02	GO:0016568	chromatin modification
1.81	1.77e-02	GO:0070727	cellular macromolecule localization
1.31	1.86e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79	2.92e-02	GO:0034613	cellular protein localization
1.38	4.59e-02	GO:0006464	protein modification process
1.37	4.81e-02	GO:0043412	macromolecule modification
1.32	4.83e-02	GO:0044267	cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.25	1.73e-15	GO:0043227	membrane-bounded organelle
1.25	2.12e-15	GO:0043231	intracellular membrane-bounded organelle
1.21	1.08e-12	GO:0043229	intracellular organelle
1.21	1.11e-12	GO:0043226	organelle
1.17	2.85e-12	GO:0044424	intracellular part
1.15	5.28e-11	GO:0005622	intracellular
1.30	2.68e-09	GO:0044446	intracellular organelle part
1.30	3.44e-09	GO:0044422	organelle part
1.20	9.31e-08	GO:0005737	cytoplasm
1.27	3.97e-07	GO:0005634	nucleus
1.55	6.12e-06	GO:0012505	endomembrane system
1.46	6.40e-06	GO:0031090	organelle membrane
1.23	7.26e-06	GO:0044444	cytoplasmic part
2.04	1.75e-05	GO:0000139	Golgi membrane
1.69	2.05e-05	GO:0005794	Golgi apparatus
1.88	7.03e-05	GO:0044431	Golgi apparatus part
1.40	2.05e-04	GO:0044428	nuclear part
1.44	2.40e-04	GO:0031981	nuclear lumen
1.50	1.14e-03	GO:0005654	nucleoplasm
1.52	3.76e-03	GO:0005783	endoplasmic reticulum
2.14	9.29e-03	GO:0000785	chromatin
1.32	1.23e-02	GO:0070013	intracellular organelle lumen
1.31	1.77e-02	GO:0031974	membrane-enclosed lumen
1.31	1.95e-02	GO:0043233	organelle lumen
1.56	2.78e-02	GO:0044432	endoplasmic reticulum part
1.60	3.00e-02	GO:0005789	endoplasmic reticulum membrane
1.57	3.62e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
1.56	3.86e-02	GO:0031988	membrane-bounded vesicle
2.13	3.88e-02	GO:0030135	coated vesicle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	3.25e-03	GO:0005515	protein binding
1.83	3.37e-02	GO:0003712	transcription cofactor activity
1.82	3.61e-02	GO:0000988	protein binding transcription factor activity
1.82	3.61e-02	GO:0000989	transcription factor binding transcription factor activity