Motif ID: CACAGUG

Z-value: 0.813


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_13590624 1.670 NM_001004019
NM_001998
FBLN2

fibulin 2

chr13_-_37494370 1.641 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr3_+_13610239 1.632 NM_001165035
FBLN2
fibulin 2
chr6_-_24911194 1.520 NM_014722
FAM65B
family with sequence similarity 65, member B
chr19_-_7293876 1.179 NM_000208
NM_001079817
INSR

insulin receptor

chr14_+_67999915 1.176 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_-_57755787 1.173 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr1_-_75139421 1.172 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr14_+_56584854 1.083 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr1_-_92351613 1.076 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr19_+_32897021 1.074 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr20_-_7921068 1.066 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr19_+_32896515 1.026 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr14_-_89883306 1.025 NM_005197
FOXN3
forkhead box N3
chr6_-_56112315 1.004 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr14_+_100259445 0.998 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr8_+_1922030 0.984 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr12_-_63328663 0.980 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_-_90085325 0.977 NM_001085471
FOXN3
forkhead box N3
chr1_-_92371558 0.951 NM_001195684
TGFBR3
transforming growth factor, beta receptor III

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 80 entries
enrichment   p-value GO term description
3.35 1.28e-06 GO:0007389 pattern specification process
3.34 1.37e-02 GO:0016570 histone modification
3.28 1.76e-02 GO:0016569 covalent chromatin modification
3.01 1.80e-03 GO:0035295 tube development
2.93 7.74e-03 GO:0045596 negative regulation of cell differentiation
2.83 3.59e-04 GO:0048598 embryonic morphogenesis
2.78 8.28e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.68 1.05e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.66 4.09e-04 GO:0032583 regulation of gene-specific transcription
2.60 7.62e-03 GO:0016568 chromatin modification
2.55 1.12e-05 GO:0045893 positive regulation of transcription, DNA-dependent
2.44 2.23e-03 GO:0031175 neuron projection development
2.43 3.51e-05 GO:0051254 positive regulation of RNA metabolic process
2.41 4.75e-05 GO:0010628 positive regulation of gene expression
2.40 3.38e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.39 6.90e-03 GO:0072358 cardiovascular system development
2.39 6.90e-03 GO:0072359 circulatory system development
2.35 3.57e-02 GO:0007409 axonogenesis
2.34 1.47e-03 GO:0048666 neuron development
2.33 3.18e-03 GO:0051253 negative regulation of RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
4.99 4.76e-02 GO:0044309 neuron spine
2.69 1.11e-02 GO:0005667 transcription factor complex
2.25 1.70e-02 GO:0045202 synapse
1.84 4.70e-02 GO:0044451 nucleoplasm part
1.26 1.42e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.94 1.01e-04 GO:0016563 transcription activator activity
2.79 6.39e-03 GO:0003702 RNA polymerase II transcription factor activity
2.78 3.87e-02 GO:0000975 regulatory region DNA binding
2.78 3.87e-02 GO:0001067 regulatory region nucleic acid binding
2.78 3.87e-02 GO:0044212 transcription regulatory region DNA binding
2.73 2.57e-03 GO:0008134 transcription factor binding
2.49 1.68e-02 GO:0016564 transcription repressor activity
2.43 1.10e-03 GO:0019904 protein domain specific binding
2.38 8.47e-06 GO:0043565 sequence-specific DNA binding
2.36 4.14e-09 GO:0030528 transcription regulator activity
2.11 6.71e-06 GO:0001071 nucleic acid binding transcription factor activity
2.11 6.71e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 3.45e-02 GO:0003677 DNA binding