Motif ID: CDC5L.p2

Z-value: 0.979


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44355250-0.163.9e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_111126706 2.634 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr2_+_228678556 2.599 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr2_-_216241321 2.514 FN1
fibronectin 1
chr18_-_31628557 2.251 NM_001198549
NOL4
nucleolar protein 4
chr7_+_80267922 1.764 CD36
CD36 molecule (thrombospondin receptor)
chr4_+_41614933 1.643 LIMCH1
LIM and calponin homology domains 1
chr18_+_61442611 1.539 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr8_+_39771327 1.477 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr4_-_69111333 1.443 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr5_+_147443534 1.442 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr2_-_161056573 1.412 NM_000888
ITGB6
integrin, beta 6
chr4_+_74606222 1.383 NM_000584
IL8
interleukin 8
chr10_+_118187381 1.372 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr9_+_105757592 1.247 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr12_+_8975149 1.237 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr12_-_91398757 1.226 NM_004950
EPYC
epiphycan
chr2_+_210444364 1.152 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr1_-_76076762 1.087 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr4_+_41614725 1.040 LIMCH1
LIM and calponin homology domains 1
chrX_-_15683153 1.013 NM_020665
TMEM27
transmembrane protein 27
chr17_-_7493389 0.943 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr9_-_110252045 0.922 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr12_+_13349720 0.922 EMP1
epithelial membrane protein 1
chr12_-_91505541 0.911 NM_002345
LUM
lumican
chr4_-_159093717 0.872 NM_016613
FAM198B
family with sequence similarity 198, member B
chr19_-_14889347 0.855 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr4_+_169013687 0.850 NM_007193
ANXA10
annexin A10
chr1_+_152956563 0.840 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr2_-_161056762 0.831 ITGB6
integrin, beta 6
chr9_+_125132823 0.813 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_80267972 0.801 CD36
CD36 molecule (thrombospondin receptor)
chr21_+_43619798 0.797 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr15_-_99789585 0.794 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr12_-_91573264 0.772 NM_133503
DCN
decorin
chr4_-_68749698 0.771 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chrX_+_135230736 0.764 NM_001159700
FHL1
four and a half LIM domains 1
chr13_+_32313678 0.747 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr1_-_204135420 0.696 NM_000537
REN
renin
chr2_-_215896809 0.686 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr12_-_53601051 0.686 ITGB7
integrin, beta 7
chr10_-_90611675 0.682 NM_144590
ANKRD22
ankyrin repeat domain 22
chr4_+_155484131 0.672 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr8_+_27179918 0.671 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr6_-_111894897 0.656 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr1_+_84609941 0.646 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_152974222 0.631 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr16_-_71610948 0.630 NM_000353
TAT
tyrosine aminotransferase
chr17_-_2966900 0.622 NM_014566
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr15_-_74495528 0.617 NM_001142618
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr2_-_163099877 0.612 NM_004460
FAP
fibroblast activation protein, alpha
chr2_+_132480063 0.594 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr1_+_84630575 0.590 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chrX_+_37892786 0.586 NM_001163334
SYTL5
synaptotagmin-like 5
chrX_+_99839789 0.559 NM_022144
TNMD
tenomodulin
chr4_+_70796798 0.554 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr2_+_102508377 0.552 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr18_+_616671 0.546 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr6_-_133084585 0.544 NM_078488
VNN2
vanin 2
chr12_-_68619535 0.542 NM_018402
IL26
interleukin 26
chr2_-_15701445 0.539 NM_015909
NBAS
neuroblastoma amplified sequence
chr15_-_31947541 0.533 NM_130901
OTUD7A
OTU domain containing 7A
chr2_-_225370687 0.525 CUL3
cullin 3
chr17_-_39150384 0.524 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr1_-_89641722 0.520 NM_207398
GBP7
guanylate binding protein 7
chr20_-_34241830 0.519 NM_003915
CPNE1
copine I
chr20_-_13971256 0.519 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr2_+_102508333 0.519 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_+_143412938 0.517 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr12_+_93096618 0.517 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr2_-_216003068 0.509 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_205391180 0.505 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr1_+_115572414 0.501 NM_000549
TSHB
thyroid stimulating hormone, beta
chr4_+_39063851 0.500 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr18_+_61554938 0.496 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr19_+_48758931 0.494 LOC100505812
uncharacterized LOC100505812
chr4_+_69313166 0.488 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr10_+_126630691 0.487 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr4_-_123377471 0.486 NM_000586
IL2
interleukin 2
chr10_-_69752385 0.486 HERC4
hect domain and RLD 4
chr6_-_49604524 0.482 NM_000324
RHAG
Rh-associated glycoprotein
chr1_+_202431870 0.481 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr6_+_125304509 0.471 NM_152553
RNF217
ring finger protein 217
chr20_+_20037289 0.464 NM_001167816
C20orf26
chromosome 20 open reading frame 26
chr5_-_138210992 0.462 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr17_+_37856174 0.455


chr7_+_123295860 0.454 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr4_-_15940362 0.450 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr21_+_30517897 0.447 C21orf7
chromosome 21 open reading frame 7
chr10_-_70066594 0.446 PBLD
phenazine biosynthesis-like protein domain containing
chr6_+_27107060 0.445 NM_003495
HIST2H4B
HIST1H4I
histone cluster 2, H4b
histone cluster 1, H4i
chr20_-_34243118 0.443 RBM12
RNA binding motif protein 12
chr1_+_153003677 0.443 NM_003125
SPRR1B
small proline-rich protein 1B
chr20_-_39928708 0.443 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr1_+_151630710 0.442 SNX27
sorting nexin family member 27
chr3_-_138478184 0.437 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr2_-_31440378 0.436 NM_001145122
CAPN14
calpain 14
chr5_+_140792507 0.435 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr6_-_66417069 0.435 NM_001142800
NM_001142801
EYS

eyes shut homolog (Drosophila)

chr12_-_80307690 0.430 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr5_-_138211054 0.429 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr5_+_92918924 0.419 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr1_-_231560789 0.419 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr3_+_186358148 0.409 NM_014375
FETUB
fetuin B
chr17_+_37856224 0.407 ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr6_+_105404922 0.405 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr7_+_18535351 0.398 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr10_-_106098161 0.398 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr10_-_21186530 0.397 NM_006393
NEBL
nebulette
chr4_+_95376396 0.396 PDLIM5
PDZ and LIM domain 5
chrX_-_131261871 0.391 NM_194277
FRMD7
FERM domain containing 7
chr2_-_61245363 0.391 NM_144709
PUS10
pseudouridylate synthase 10
chr18_-_31802433 0.388 NM_001198547
NOL4
nucleolar protein 4
chr2_+_167744996 0.386 NM_001079810
NM_001199143
NM_152381
XIRP2


xin actin-binding repeat containing 2


chr2_+_74120092 0.385 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr12_-_91576579 0.377 DCN
decorin
chr12_+_80603232 0.376 NM_173591
OTOGL
otogelin-like
chr10_+_225932 0.376 NM_001202467
NM_001202468
ZMYND11

zinc finger, MYND-type containing 11

chr4_+_119948554 0.376 SYNPO2
synaptopodin 2
chr16_+_69680959 0.373 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_+_74120132 0.371 ACTG2
actin, gamma 2, smooth muscle, enteric
chr2_+_204571197 0.368 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr12_-_121248679 0.365 SPPL3
signal peptide peptidase-like 3
chr12_+_21168629 0.365 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_-_91576805 0.361 NM_001920
DCN
decorin
chr15_+_71839540 0.359 THSD4
thrombospondin, type I, domain containing 4
chr2_+_204571379 0.356 CD28
CD28 molecule
chr1_+_89829435 0.356 NM_198460
GBP6
guanylate binding protein family, member 6
chr18_-_24445652 0.355 NM_001650
AQP4
aquaporin 4
chr5_-_27038650 0.354 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr11_+_89657231 0.353 NM_001105522
TRIM49L1
tripartite motif containing 49-like 1
chr11_+_33363104 0.352 HIPK3
homeodomain interacting protein kinase 3
chr7_+_80267782 0.351 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr5_+_96212167 0.348 ERAP2
endoplasmic reticulum aminopeptidase 2
chr7_-_108142934 0.345 PNPLA8
patatin-like phospholipase domain containing 8
chr11_-_89653575 0.345 NM_001105522
TRIM49L1
tripartite motif containing 49-like 1
chr10_-_29754478 0.341 SVIL
supervillin
chr1_-_155774769 0.337 GON4L
gon-4-like (C. elegans)
chr12_-_25150372 0.336 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr3_+_121774208 0.335 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr8_+_22210311 0.334 PIWIL2
piwi-like 2 (Drosophila)
chr9_+_22446783 0.333 NM_022160
DMRTA1
DMRT-like family A1
chr8_-_57906143 0.333 IMPAD1
inositol monophosphatase domain containing 1
chr16_-_47005339 0.331 DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chrX_+_48916515 0.329 NM_001163322
NM_033626
NM_001163321
NM_001163323
CCDC120



coiled-coil domain containing 120



chr4_+_187187117 0.329 NM_000128
F11
coagulation factor XI
chrX_+_135251795 0.325 NM_001167819
FHL1
four and a half LIM domains 1
chr9_+_75766794 0.321 ANXA1
annexin A1
chr6_+_20534686 0.321 NM_017774
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr20_-_1472168 0.318 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr12_-_46633551 0.314 SLC38A1
solute carrier family 38, member 1
chr12_-_53600999 0.312 NM_000889
ITGB7
integrin, beta 7
chr19_-_21646685 0.306


chrX_+_91090459 0.304 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr7_-_16505292 0.302 NM_015464
SOSTDC1
sclerostin domain containing 1
chr13_-_110802708 0.301 COL4A1
collagen, type IV, alpha 1
chr4_+_41614911 0.300 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr3_-_196911001 0.299 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr18_+_19353635 0.297 MIB1
mindbomb homolog 1 (Drosophila)
chr7_+_77469446 0.297 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr4_-_15939949 0.293 FGFBP1
fibroblast growth factor binding protein 1
chr2_+_207406815 0.292 ADAM23
ADAM metallopeptidase domain 23
chr13_-_38172862 0.290 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr20_+_42984338 0.288 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr1_+_22979681 0.286 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr14_-_101036130 0.281 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr2_+_190540710 0.281 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr8_+_49984902 0.280 NM_001007176
C8orf22
chromosome 8 open reading frame 22
chr10_+_118305427 0.280 NM_000936
PNLIP
pancreatic lipase
chr9_+_75766777 0.275 NM_000700
ANXA1
annexin A1
chr4_+_88720701 0.275 NM_004967
IBSP
integrin-binding sialoprotein
chr4_-_165118862 0.275 NM_012403
ANP32C
acidic (leucine-rich) nuclear phosphoprotein 32 family, member C
chr10_-_74283693 0.272 NM_001195519
MICU1
mitochondrial calcium uptake 1
chr15_-_55562483 0.272 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr6_-_71012750 0.271 NM_001851
COL9A1
collagen, type IX, alpha 1
chr2_+_33359607 0.268 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr5_+_149887673 0.268 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr22_+_51041561 0.267 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr5_+_143191725 0.267 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr13_-_99630243 0.266 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr3_-_64672285 0.266 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr4_+_71587674 0.266 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr4_+_15341559 0.265 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr15_+_80364902 0.263 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr5_-_39270708 0.262 NM_001243093
FYB
FYN binding protein
chrX_+_135278912 0.262 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr15_-_56209305 0.262 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr1_-_163113938 0.261 RGS5
regulator of G-protein signaling 5
chr5_+_55062712 0.258 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr6_-_155777036 0.258 NM_015718
NOX3
NADPH oxidase 3
chr18_-_48346297 0.257 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr12_+_101988746 0.256 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr11_-_118134956 0.256 MPZL2
myelin protein zero-like 2
chr3_-_129599220 0.254 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr3_+_122044010 0.251 NM_005213
CSTA
cystatin A (stefin A)
chrX_+_85517970 0.251 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr8_-_133117511 0.251 NM_001145095
HHLA1
HERV-H LTR-associating 1
chr19_-_4540035 0.246 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr20_-_45061554 0.243 ELMO2
engulfment and cell motility 2
chr9_+_96846710 0.242 NM_001253829
NM_152422
PTPDC1

protein tyrosine phosphatase domain containing 1

chr12_+_106994914 0.238 NM_001206691
RFX4
regulatory factor X, 4 (influences HLA class II expression)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.76 5.99e-04 GO:0018149 peptide cross-linking
1.88 1.25e-03 GO:0009611 response to wounding
2.00 1.42e-02 GO:0042060 wound healing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 1.49e-03 GO:0005576 extracellular region
1.59 4.23e-02 GO:0044421 extracellular region part

Nothing significant found in function category.