Motif ID: CREB1.p2

Z-value: 1.425


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2083946150.604.7e-04Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_22634373 6.848 NM_001253854
NM_001253855
NM_012443
NM_172242
 SPAG6



sperm associated antigen 6



chr21_-_43916298 6.466 NM_080860
 RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr3_-_197686837 4.214 NM_032263
 IQCG
IQ motif containing G
chr12_-_94853453 4.060 CCDC41
coiled-coil domain containing 41
chr16_+_19078958 3.810 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr16_-_66959418 3.751 NM_001128850
NM_004165
 RRAD

Ras-related associated with diabetes

chr6_+_163149001 3.599 NM_001080379
 PACRG
PARK2 co-regulated
chr19_-_46088021 3.521 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr15_+_78556485 3.329 NM_018602
 DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr11_-_119252267 3.171 USP2
ubiquitin specific peptidase 2
chrX_-_44202834 3.059 NM_025184
 EFHC2
EF-hand domain (C-terminal) containing 2
chrX_+_152240726 2.903 NM_001170944
NM_001242319
NM_032882
 PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr19_+_54058493 2.876 NM_001079907
 ZNF331
zinc finger protein 331
chr6_-_43478423 2.783 NM_001012974
 LRRC73
leucine rich repeat containing 73
chr7_-_73184535 2.761 NM_001306
 CLDN3
claudin 3
chr6_-_43477980 2.736 LRRC73
leucine rich repeat containing 73
chr8_-_110661007 2.732 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
 SYBU




syntabulin (syntaxin-interacting)




chr14_+_74486049 2.714 NM_025057
 C14orf45
chromosome 14 open reading frame 45
chr16_+_19078916 2.693 NM_016138
 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_158288952 2.662 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
 MLF1





myeloid leukemia factor 1






Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
3.00 8.37e-04 GO:0006403 RNA localization
3.00 3.96e-03 GO:0051028 mRNA transport
2.99 1.57e-03 GO:0050657 nucleic acid transport
2.99 1.57e-03 GO:0050658 RNA transport
2.99 1.57e-03 GO:0051236 establishment of RNA localization
2.70 6.05e-05 GO:0000375 RNA splicing, via transesterification reactions
2.70 9.61e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.70 9.61e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.57 2.67e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.43 1.38e-05 GO:0008380 RNA splicing
2.32 2.43e-06 GO:0006397 mRNA processing
2.23 5.48e-10 GO:0006396 RNA processing
2.17 3.79e-07 GO:0016071 mRNA metabolic process
1.97 8.13e-04 GO:0006325 chromatin organization
1.95 3.86e-02 GO:0006281 DNA repair
1.86 4.25e-03 GO:0006974 response to DNA damage stimulus
1.84 6.57e-04 GO:0051276 chromosome organization
1.84 4.79e-03 GO:0044265 cellular macromolecule catabolic process
1.80 2.86e-05 GO:0033554 cellular response to stress
1.74 1.96e-02 GO:0006259 DNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
2.86 4.85e-02 GO:0071013 catalytic step 2 spliceosome
2.82 1.35e-03 GO:0016607 nuclear speck
2.74 9.67e-04 GO:0005681 spliceosomal complex
2.32 8.14e-04 GO:0016604 nuclear body
1.92 1.31e-04 GO:0005730 nucleolus
1.87 2.29e-02 GO:0005815 microtubule organizing center
1.84 6.06e-12 GO:0005654 nucleoplasm
1.81 1.97e-05 GO:0044451 nucleoplasm part
1.79 1.53e-15 GO:0031981 nuclear lumen
1.69 1.05e-14 GO:0044428 nuclear part
1.67 2.14e-02 GO:0005694 chromosome
1.67 3.47e-02 GO:0030529 ribonucleoprotein complex
1.65 1.59e-13 GO:0070013 intracellular organelle lumen
1.63 2.64e-13 GO:0031974 membrane-enclosed lumen
1.62 9.08e-13 GO:0043233 organelle lumen
1.60 1.23e-02 GO:0031967 organelle envelope
1.58 2.24e-02 GO:0031975 envelope
1.57 4.07e-02 GO:0044429 mitochondrial part
1.44 2.42e-21 GO:0005634 nucleus
1.35 2.85e-13 GO:0044446 intracellular organelle part

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.85 6.32e-03 GO:0008026 ATP-dependent helicase activity
2.85 6.32e-03 GO:0070035 purine NTP-dependent helicase activity
2.47 1.89e-02 GO:0004386 helicase activity
1.92 2.78e-08 GO:0003723 RNA binding
1.89 1.68e-02 GO:0016887 ATPase activity
1.46 3.39e-11 GO:0003676 nucleic acid binding
1.45 1.22e-03 GO:0005524 ATP binding
1.43 2.84e-03 GO:0032559 adenyl ribonucleotide binding
1.42 1.27e-05 GO:0000166 nucleotide binding
1.42 4.81e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.42 3.83e-03 GO:0030554 adenyl nucleotide binding
1.40 1.37e-03 GO:0032553 ribonucleotide binding
1.40 1.37e-03 GO:0032555 purine ribonucleotide binding
1.39 1.94e-03 GO:0017076 purine nucleotide binding
1.35 1.15e-03 GO:0003677 DNA binding
1.15 3.00e-03 GO:0005515 protein binding
1.10 2.28e-05 GO:0005488 binding