Motif ID: CRX.p2

Z-value: 0.853


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CRXchr19_+_48325098-0.496.1e-03Click!


Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_7921068 2.786 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr3_-_19975671 2.378 NM_144715
EFHB
EF-hand domain family, member B
chr17_+_68100994 1.896 NM_170742
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_-_86001197 1.816 NM_015613
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr4_+_81106423 1.316 NM_020226
PRDM8
PR domain containing 8
chr11_-_102668892 1.298 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr17_-_39280377 1.215 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr3_+_149192367 1.130 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr3_+_97158453 1.112 NM_173655
EPHA6
EPH receptor A6
chr11_+_61717355 1.100 NM_001139443
NM_004183
BEST1

bestrophin 1

chr4_+_88896868 1.008 SPP1
secreted phosphoprotein 1
chr13_-_61989209 0.958 PCDH20
protocadherin 20
chr12_-_91398744 0.955 EPYC
epiphycan
chr11_+_118175294 0.899 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr7_-_138363789 0.898 NM_001139456
SVOPL
SVOP-like
chrY_+_16634487 0.892 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr4_+_88896899 0.846 SPP1
secreted phosphoprotein 1
chr4_+_88896838 0.816 SPP1
secreted phosphoprotein 1
chr20_+_9288446 0.809 NM_000933
PLCB4
phospholipase C, beta 4
chr17_-_39334439 0.790 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr1_+_171217632 0.777 NM_002021
FMO1
flavin containing monooxygenase 1
chr7_+_141463896 0.774 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr2_+_61292999 0.766 NM_001129993
KIAA1841
KIAA1841
chr17_+_39261640 0.754 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr1_-_161337663 0.750 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr19_-_51893791 0.716 NM_001193623
LOC147646
uncharacterized LOC147646
chr12_+_7942025 0.710 NANOG
Nanog homeobox
chr12_-_25706177 0.670 NM_152590
NM_001145728
NM_001145729
IFLTD1


intermediate filament tail domain containing 1


chrM_+_9182 0.665


chr9_+_12693385 0.660 NM_000550
TYRP1
tyrosinase-related protein 1
chrM_+_8857 0.652


chr11_+_60467046 0.635 NM_031457
MS4A8B
membrane-spanning 4-domains, subfamily A, member 8B
chr9_-_114090712 0.619 NM_205859
OR2K2
olfactory receptor, family 2, subfamily K, member 2
chr12_-_4488707 0.615 NM_020638
FGF23
fibroblast growth factor 23
chr21_-_40816127 0.614 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr8_-_10512616 0.613 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr16_+_57728711 0.608 NM_032269
CCDC135
coiled-coil domain containing 135
chr11_-_116663106 0.607 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr1_+_114522029 0.602 NM_020190
OLFML3
olfactomedin-like 3
chr22_-_30867944 0.590 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr16_-_28414940 0.580 EIF3C
eukaryotic translation initiation factor 3, subunit C
chr4_+_187070326 0.574 NM_001006655
FAM149A
family with sequence similarity 149, member A
chrX_+_41548225 0.569 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr4_+_186350543 0.560 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr16_+_28722781 0.559 NM_001099661
NM_001037808
NM_003752
EIF3CL
EIF3C

eukaryotic translation initiation factor 3, subunit C-like
eukaryotic translation initiation factor 3, subunit C

chr12_-_111358353 0.536 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr22_-_42336222 0.525 NM_001110215
CENPM
centromere protein M
chr8_+_1952875 0.523 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr9_-_4152182 0.519 NM_152629
GLIS3
GLIS family zinc finger 3
chr14_-_61748193 0.498


chr20_-_44006876 0.497 NM_014477
TP53TG5
TP53 target 5
chr19_+_46001730 0.497 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr7_-_122339186 0.497 NM_139175
RNF133
ring finger protein 133
chrM_+_9217 0.494


chr17_+_7591666 0.493 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr12_-_15091441 0.486 NM_152321
ERP27
endoplasmic reticulum protein 27
chr17_+_3118911 0.485 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr3_+_160394946 0.473 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr5_-_159739482 0.457 NM_024565
CCNJL
cyclin J-like
chrX_-_117107700 0.450 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chrX_+_17653412 0.445 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_217113007 0.433 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr1_+_171283372 0.427 NM_002022
FMO4
flavin containing monooxygenase 4
chr16_+_21689834 0.426 NM_144672
OTOA
otoancorin
chr18_+_61582744 0.425 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_90604185 0.424 NM_032602
GJA10
gap junction protein, alpha 10, 62kDa
chr3_+_149192479 0.420 TM4SF4
transmembrane 4 L six family member 4
chr1_+_40713572 0.418 NM_001008740
TMCO2
transmembrane and coiled-coil domains 2
chr6_+_52284948 0.418 NM_018100
EFHC1
EF-hand domain (C-terminal) containing 1
chr17_-_9808496 0.413 NM_002903
RCVRN
recoverin
chrY_+_2803409 0.408 NM_001145275
NM_003411
ZFY

zinc finger protein, Y-linked

chr1_-_241799101 0.407 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr13_-_36429798 0.406 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr6_-_31697568 0.403 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_-_64727608 0.402 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr3_+_49059490 0.400 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr1_+_179560747 0.398 NM_001199091
NM_001199085
NM_173533
TDRD5


tudor domain containing 5


chr2_-_188312872 0.398 NM_005795
CALCRL
calcitonin receptor-like
chr7_-_142659397 0.397 KEL
Kell blood group, metallo-endopeptidase
chr9_-_8733893 0.396 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr20_-_3762060 0.395 NM_015417
SPEF1
sperm flagellar 1
chr17_-_42908178 0.389 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr12_+_7941994 0.388 NM_024865
NANOG
Nanog homeobox
chr16_+_58010338 0.374 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr14_-_24777153 0.372 CIDEB
cell death-inducing DFFA-like effector b
chr12_-_71148063 0.372 PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_196621007 0.371 NM_000186
NM_001014975
CFH

complement factor H

chr11_+_73357222 0.370 NM_001130033
NM_021200
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr9_+_1050333 0.366 NM_006557
NM_001130865
DMRT2

doublesex and mab-3 related transcription factor 2

chr21_+_31768294 0.365 NM_181599
KRTAP13-1
keratin associated protein 13-1
chr12_-_11175169 0.365 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr14_-_73360792 0.360 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr4_+_71108304 0.357 NM_005212
CSN3
casein kappa
chr2_+_152214105 0.355 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_236681513 0.354 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr4_-_140060601 0.350 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr16_-_5116030 0.349 NM_001098514
NM_152459
C16orf89

chromosome 16 open reading frame 89

chr14_-_24777160 0.348 CIDEB
cell death-inducing DFFA-like effector b
chr14_-_24777184 0.347 CIDEB
cell death-inducing DFFA-like effector b
chr1_+_20396652 0.344 NM_000929
PLA2G5
phospholipase A2, group V
chr10_+_102732285 0.341 NM_001203244
NM_017893
SEMA4G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

chr18_-_24722757 0.341 NM_001243848
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr6_+_46761093 0.339 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr8_+_74903563 0.339 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr5_-_169724614 0.338 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_-_15333726 0.337 NM_001201583
NM_080873
ASB11

ankyrin repeat and SOCS box containing 11

chr9_-_117444368 0.336 NM_001199233
LOC100505478
uncharacterized LOC100505478
chr6_-_80247103 0.336 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr3_+_99833773 0.336 NM_001167924
C3orf26
chromosome 3 open reading frame 26
chr11_+_112047088 0.330 NM_001037290
BCO2
beta-carotene oxygenase 2
chr1_-_155006235 0.328 NM_144622
DCST2
DC-STAMP domain containing 2
chr1_+_32712817 0.322 NM_032648
FAM167B
family with sequence similarity 167, member B
chr12_+_12224401 0.322 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr7_-_138348968 0.319 NM_174959
SVOPL
SVOP-like
chr13_+_43355685 0.316 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr6_-_139613114 0.316 NM_153235
TXLNB
taxilin beta
chr11_-_5323174 0.316 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr1_+_12806162 0.313 NM_152290
C1orf158
chromosome 1 open reading frame 158
chr3_+_50306305 0.312 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_-_144385647 0.310 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr21_-_35884503 0.309 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr12_+_109554391 0.309 ACACB
acetyl-CoA carboxylase beta
chr4_+_36283243 0.307 NM_001136536
DTHD1
death domain containing 1
chr3_-_109056388 0.306 NM_018189
DPPA4
developmental pluripotency associated 4
chr1_+_170904611 0.305 NM_001163629
NM_025063
C1orf129

chromosome 1 open reading frame 129

chr12_-_121454285 0.305 NM_022895
C12orf43
chromosome 12 open reading frame 43
chr4_+_88896801 0.304 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr12_-_56236614 0.304 NM_002429
MMP19
matrix metallopeptidase 19
chr14_+_58906398 0.304 NM_001244193
KIAA0586
KIAA0586
chr11_+_71791376 0.303 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr11_-_59950498 0.303 NM_022349
NM_152851
MS4A6A

membrane-spanning 4-domains, subfamily A, member 6A

chr3_+_158787040 0.303 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr6_-_149806116 0.298 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr7_-_138482848 0.297 NM_020632
NM_130840
ATP6V0A4

ATPase, H+ transporting, lysosomal V0 subunit a4

chr1_+_61547388 0.296 NM_001145512
NFIA
nuclear factor I/A
chr2_-_190927321 0.295 NM_005259
MSTN
myostatin
chr12_-_7818467 0.291 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr8_-_87755880 0.290 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr9_+_1050367 0.289 DMRT2
doublesex and mab-3 related transcription factor 2
chr20_-_1638359 0.289 NM_001039508
NM_018556
NM_080816
SIRPG


signal-regulatory protein gamma


chr7_+_150102376 0.288


chr2_-_111435604 0.287 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chrX_+_110339374 0.285 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr17_+_42977141 0.285 NM_213607
CCDC103
coiled-coil domain containing 103
chr20_-_44516237 0.284 NM_080608
SPATA25
spermatogenesis associated 25
chr12_-_11184005 0.283 NM_176885
TAS2R31
taste receptor, type 2, member 31
chr11_-_102668822 0.280 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr7_-_142659412 0.279 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr6_+_159309618 0.277 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chr9_-_100700422 0.274 NM_197978
HEMGN
hemogen
chr9_-_112970412 0.272 NM_001012993
C9orf152
chromosome 9 open reading frame 152
chrX_-_1331526 0.271 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr10_-_82049178 0.270 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr11_+_15133969 0.269 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr2_-_152146373 0.268 NM_004688
NMI
N-myc (and STAT) interactor
chrX_+_64708614 0.267 NM_001010888
ZC3H12B
zinc finger CCCH-type containing 12B
chr1_+_214776582 0.266 CENPF
centromere protein F, 350/400kDa (mitosin)
chr11_-_118900078 0.263 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr11_+_7618416 0.263 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_217540722 0.263 IGFBP5
insulin-like growth factor binding protein 5
chr1_+_207277577 0.263 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr15_-_55800431 0.262 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr7_-_18067445 0.261 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr17_-_47286742 0.261 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chrX_+_100333835 0.261 NM_021637
TMEM35
transmembrane protein 35
chrX_-_112066353 0.260 NM_001113490
AMOT
angiomotin
chr3_+_49059046 0.260 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chrX_-_117119282 0.259 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr12_-_52761254 0.259 NM_002283
KRT85
keratin 85
chr20_+_31805118 0.259 NM_001042439
NM_178466
BPIFA3

BPI fold containing family A, member 3

chr4_+_124330 0.258 ZNF718
zinc finger protein 718
chr12_-_16758312 0.257 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_+_100432160 0.256 NM_032149
C4orf17
chromosome 4 open reading frame 17
chr14_+_88852065 0.256 SPATA7
spermatogenesis associated 7
chr22_+_22676814 0.256


chrX_+_144902865 0.256 NM_001144006
NM_001144008
NM_001144009
NM_001144010
SLITRK2



SLIT and NTRK-like family, member 2



chr1_-_7913094 0.254 NM_006786
UTS2
urotensin 2
chrX_+_110366304 0.254 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr12_-_52604488 0.253 NM_001242696
LOC283403
uncharacterized LOC283403
chr10_-_124605690 0.252 NM_022034
CUZD1
CUB and zona pellucida-like domains 1
chr9_+_97521930 0.251 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr11_-_55703875 0.251 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr1_-_48937791 0.251 NM_019073
SPATA6
spermatogenesis associated 6
chr10_-_118680978 0.251 KIAA1598
KIAA1598
chr3_+_50306578 0.250 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr11_-_62911692 0.249 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr1_+_43312259 0.248 ZNF691
zinc finger protein 691
chr3_-_112218383 0.247 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr12_-_2027802 0.247 NM_172364
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr3_-_109056333 0.246 DPPA4
developmental pluripotency associated 4
chr12_+_7341758 0.245 NM_001131026
PEX5
peroxisomal biogenesis factor 5
chr6_+_16143281 0.242 MYLIP
myosin regulatory light chain interacting protein
chr15_+_81426605 0.242 NM_173528
C15orf26
chromosome 15 open reading frame 26
chr3_-_107941168 0.242 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr11_+_61976139 0.240 NM_002407
SCGB2A1
secretoglobin, family 2A, member 1
chr1_+_167064086 0.239 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr12_-_54758228 0.238 NM_020370
GPR84
G protein-coupled receptor 84
chr12_-_122107559 0.237 NM_173855
MORN3
MORN repeat containing 3
chr8_+_17396285 0.237 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr2_+_68592432 0.236 PLEK
pleckstrin

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.