Motif ID: CUACAGU

Z-value: 0.253


Mature miRNA associated with seed CUACAGU:

NamemiRBase Accession
hsa-miR-139-5p MIMAT0000250



Activity profile for motif CUACAGU.

activity profile for motif CUACAGU


Sorted Z-values histogram for motif CUACAGU

Sorted Z-values for motif CUACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUACAGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_148651395 0.116 NM_001146337
NM_152406
AFAP1L1

actin filament associated protein 1-like 1

chr14_+_100259445 0.114 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chrX_+_16804531 0.106 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr7_+_94285620 0.106 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr2_+_128403438 0.103 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr7_+_94285676 0.101 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr16_+_58534045 0.088 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr1_+_2985730 0.087 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr6_-_46138584 0.087 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr12_+_49372235 0.082 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr16_+_58497993 0.080 NM_001130487
NDRG4
NDRG family member 4
chr16_+_58497548 0.080 NM_020465
NDRG4
NDRG family member 4
chr3_-_123603144 0.079 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr8_+_81398416 0.078 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr19_-_57678855 0.073 NM_001012729
DUXA
double homeobox A
chr3_-_123339423 0.072 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr1_-_245027808 0.072 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr11_-_118016134 0.070 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr11_-_118023534 0.069 NM_001142348
NM_174934
SCN4B

sodium channel, voltage-gated, type IV, beta

chr5_+_149109814 0.069 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr2_-_160654736 0.069 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr5_+_149151502 0.067 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr16_+_58498725 0.066 NM_022910
NDRG4
NDRG family member 4
chr9_+_80911990 0.066 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr6_-_90121966 0.061 NM_021244
RRAGD
Ras-related GTP binding D
chr12_-_77459198 0.061 NM_203394
E2F7
E2F transcription factor 7
chr6_-_13295817 0.061 NM_001242698
LOC100130357
uncharacterized LOC100130357
chr8_+_58906968 0.060 NM_147189
FAM110B
family with sequence similarity 110, member B
chr4_-_23891608 0.059 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_+_17354562 0.059 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr16_-_75590107 0.058 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231


chr1_+_213031596 0.055 NM_014053
FLVCR1
feline leukemia virus subgroup C cellular receptor 1
chr3_-_196439067 0.055 NM_032898
CEP19
centrosomal protein 19kDa
chr5_-_132073143 0.054 NM_007054
KIF3A
kinesin family member 3A
chrX_-_25034064 0.053 NM_139058
ARX
aristaless related homeobox
chr8_+_76452202 0.052 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_85155885 0.052 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr12_-_94853696 0.051 NM_001042399
NM_016122
CCDC41

coiled-coil domain containing 41

chr15_-_74988342 0.051 NM_001142443
NM_001142444
NM_025083
EDC3


enhancer of mRNA decapping 3 homolog (S. cerevisiae)


chr11_+_120894756 0.050 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr4_-_139163222 0.050 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr11_-_128392061 0.050 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr8_+_99130067 0.050 NM_015029
POP1
processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr16_+_58283819 0.050 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr9_+_100069909 0.050 NM_020893
C9orf174
chromosome 9 open reading frame 174
chr1_-_217262946 0.048 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr1_+_245133628 0.047 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr8_+_17396285 0.047 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr2_+_178257371 0.047 NM_003659
AGPS
alkylglycerone phosphate synthase
chr8_+_99129488 0.047 NM_001145860
NM_001145861
POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chrX_-_13338517 0.046 NM_001135995
ATXN3L
ataxin 3-like
chr22_+_24105207 0.046 NM_182520
C22orf15
chromosome 22 open reading frame 15
chr9_-_125027080 0.046 NM_033117
RBM18
RNA binding motif protein 18
chr1_-_217311095 0.045 NM_001134285
ESRRG
estrogen-related receptor gamma
chr6_+_84743250 0.044 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chrX_+_37545008 0.044 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr5_+_179234002 0.044 NM_001142299
SQSTM1
sequestosome 1
chr3_-_47324255 0.043 NM_001134878
NM_022342
NM_182902
KIF9


kinesin family member 9


chr1_-_115632047 0.043 NM_005725
TSPAN2
tetraspanin 2
chr1_-_216896640 0.043 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr9_+_123850573 0.043 NM_007018
CNTRL
centriolin
chr5_+_179247841 0.043 NM_003900
SQSTM1
sequestosome 1
chr22_-_42336222 0.041 NM_001110215
CENPM
centromere protein M
chr5_+_170846659 0.041 NM_003862
FGF18
fibroblast growth factor 18
chr5_+_61714710 0.040 NM_001134779
IPO11
importin 11
chr15_-_48470453 0.040 NM_016132
MYEF2
myelin expression factor 2
chr2_+_219187858 0.040 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr16_-_46782104 0.040 NM_182493
MYLK3
myosin light chain kinase 3
chr15_-_40545109 0.040 NM_001039905
C15orf56
chromosome 15 open reading frame 56
chr13_+_24734788 0.039 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr22_-_42343079 0.039 NM_001002876
NM_024053
CENPM

centromere protein M

chr11_+_71498497 0.039 NM_001099653
NM_018172
NM_152563
FAM86C1


family with sequence similarity 86, member C1


chr5_-_81574198 0.039 NM_001025
RPS23
ribosomal protein S23
chr5_+_179233351 0.039 NM_001142298
SQSTM1
sequestosome 1
chr3_+_49449638 0.039 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr2_-_200322699 0.038 NM_001172509
SATB2
SATB homeobox 2
chr12_+_123237302 0.038 NM_003677
DENR
density-regulated protein
chr11_-_128457452 0.037 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr7_-_56119115 0.037 NM_004577
PSPH
phosphoserine phosphatase
chr2_+_149632772 0.037 NM_004522
KIF5C
kinesin family member 5C
chr13_+_39261172 0.036 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr8_+_21900389 0.036 NM_003867
FGF17
fibroblast growth factor 17
chr5_+_149340287 0.036 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr18_+_55888750 0.036 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_+_7069454 0.035 NM_001044387
NM_001044388
NM_024341
ZNF557


zinc finger protein 557


chr2_-_55920947 0.035 NM_033109
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr1_-_205782135 0.035 NM_173854
SLC41A1
solute carrier family 41, member 1
chr5_+_134240752 0.035 NM_032151
PCBD2
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr2_+_183580960 0.034 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_-_95522945 0.033 NM_144664
FAM76B
family with sequence similarity 76, member B
chr9_-_27573444 0.033 NM_018325
C9orf72
chromosome 9 open reading frame 72
chr17_+_34891340 0.033 NM_178517
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr2_+_183943286 0.033 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr7_-_44887697 0.032 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr6_+_39760772 0.032 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr6_-_109762373 0.032 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr7_+_39605871 0.032 NM_020192
YAE1D1
Yae1 domain containing 1
chr12_+_102271082 0.031 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr7_+_114055048 0.031 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr1_-_200992824 0.031 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr17_-_27621163 0.031 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr4_-_54232007 0.031 NM_152540
SCFD2
sec1 family domain containing 2
chr13_-_46756326 0.030 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr5_-_114880536 0.030 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr1_+_114496498 0.030 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr16_+_68298326 0.030 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (amino acid transporter light chain, y+L system), member 6

chr12_-_24715349 0.030 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr1_+_227751218 0.030 NM_178549
ZNF678
zinc finger protein 678
chr1_+_89990396 0.029 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr18_+_55711388 0.029 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr2_-_225450105 0.029 NM_003590
CUL3
cullin 3
chr9_+_100395704 0.029 NM_002486
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr8_+_22224997 0.029 NM_001135153
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr5_+_139175385 0.028 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr18_+_55816546 0.028 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr6_-_105584220 0.028 NM_147147
BVES
blood vessel epicardial substance
chr6_+_39760148 0.028 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_59249687 0.028 NM_002228
JUN
jun proto-oncogene
chr18_+_55714457 0.028 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_200335988 0.028 NM_015265
SATB2
SATB homeobox 2
chr6_-_105584982 0.028 NM_001199563
BVES
blood vessel epicardial substance
chr12_+_98909331 0.028 NM_001032283
NM_001032284
NM_003276
TMPO


thymopoietin


chr3_+_179370779 0.027 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr21_+_44394634 0.027 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr11_+_109964086 0.027 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr7_+_94536926 0.027 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr1_+_90024271 0.027 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_+_114493766 0.027 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr1_-_185126153 0.027 NM_001202423
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr4_-_146100793 0.026 NM_001102653
OTUD4
OTU domain containing 4
chr9_-_117554809 0.026 NM_001204344
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr1_+_150230168 0.026 NM_012113
CA14
carbonic anhydrase XIV
chr1_+_167189948 0.026 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chrX_-_134049248 0.026 NM_019556
MOSPD1
motile sperm domain containing 1
chr7_-_112726143 0.026 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr5_+_61708565 0.026 NM_016338
IPO11
importin 11
chr6_-_105584542 0.025 NM_007073
BVES
blood vessel epicardial substance
chr8_-_90996884 0.025 NM_002485
NBN
nibrin
chr18_+_55862577 0.025 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_-_77363519 0.025 NM_001168412
NM_005724
NM_198902
TSPAN3


tetraspanin 3


chr12_+_31812120 0.025 NM_173802
METTL20
methyltransferase like 20
chr5_+_68462836 0.025 NM_031966
CCNB1
cyclin B1
chr2_-_11484699 0.025 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr11_-_108368918 0.025 NM_153705
KDELC2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr6_-_108279409 0.025 NM_007214
SEC63
SEC63 homolog (S. cerevisiae)
chr1_-_225840660 0.025 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr19_+_1248548 0.025 NM_177401
MIDN
midnolin
chr1_-_70820363 0.025 NM_030816
ANKRD13C
ankyrin repeat domain 13C
chr1_+_162466963 0.025 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr3_-_15106806 0.024 NM_022497
MRPS25
mitochondrial ribosomal protein S25
chr9_+_129622935 0.024 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr1_+_61547625 0.024 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr16_-_68033355 0.024 NM_022355
DPEP2
dipeptidase 2
chr11_+_100862719 0.024 NM_032021
TMEM133
transmembrane protein 133
chr2_-_200329810 0.024 NM_001172517
SATB2
SATB homeobox 2
chr3_+_174577069 0.024 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr1_+_57110745 0.024 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr12_+_20522178 0.023 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr3_+_186648273 0.023 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr16_-_70719854 0.023 NM_138383
MTSS1L
metastasis suppressor 1-like
chr1_-_55681024 0.023 NM_015306
USP24
ubiquitin specific peptidase 24
chr2_+_170683900 0.023 NM_172070
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr8_-_105601234 0.023 NM_001135703
NM_013437
LRP12

low density lipoprotein receptor-related protein 12

chr3_+_186739643 0.023 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_+_167298280 0.023 NM_001198783
POU2F1
POU class 2 homeobox 1
chr17_-_42908178 0.023 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr4_+_71768056 0.023 NM_001244766
NM_001244767
NM_173468
MOB1B


MOB kinase activator 1B


chr3_+_101280679 0.023 NM_017819
RG9MTD1
RNA (guanine-9-) methyltransferase domain containing 1
chr17_+_40985416 0.023 NM_005789
NM_176863
PSME3

proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

chr18_+_11689135 0.023 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_51701943 0.023 NM_014372
RNF11
ring finger protein 11
chr14_+_90863302 0.023 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_-_109969058 0.022 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr17_-_42907606 0.022 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr7_+_94539209 0.022 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr2_-_27886443 0.022 NM_014860
SUPT7L
suppressor of Ty 7 (S. cerevisiae)-like
chr11_-_95657255 0.022 NM_001243571
NM_016156
NM_201278
NM_201281
MTMR2



myotubularin related protein 2



chr6_+_33168602 0.022 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr2_-_202316227 0.022 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr6_+_143999058 0.022 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_-_185125819 0.022 NM_030934
TRMT1L
TRM1 tRNA methyltransferase 1-like
chr4_+_52709165 0.022 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr12_+_31800093 0.022 NM_001135864
METTL20
methyltransferase like 20
chr16_-_72128214 0.022 NM_001142318
TXNL4B
thioredoxin-like 4B
chr2_+_191273012 0.022 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr2_-_54197786 0.022 NM_014614
PSME4
proteasome (prosome, macropain) activator subunit 4
chr9_+_27109138 0.021 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr3_-_179754516 0.021 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr22_+_17565844 0.021 NM_014339
IL17RA
interleukin 17 receptor A
chr3_+_119187782 0.021 NM_152305
POGLUT1
protein O-glucosyltransferase 1
chr2_-_172750724 0.021 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr6_-_89673347 0.021 NM_003800
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr15_+_75550898 0.021 NM_001164404
GOLGA6A
GOLGA6C
golgin A6 family, member A
golgin A6 family, member C
chr9_-_117568292 0.020 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr19_+_32897021 0.020 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr17_-_54991399 0.020 NM_005082
TRIM25
tripartite motif containing 25
chr16_-_12010518 0.020 NM_001130007
GSPT1
G1 to S phase transition 1
chr1_-_179112178 0.020 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr15_-_59949536 0.020 NM_004492
GTF2A2
general transcription factor IIA, 2, 12kDa
chr10_-_121632265 0.020 NM_024834
MCMBP
minichromosome maintenance complex binding protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 9.29e-04 GO:0009987 cellular process
1.39 1.76e-03 GO:0044260 cellular macromolecule metabolic process
2.66 1.06e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
2.68 1.40e-02 GO:0006511 ubiquitin-dependent protein catabolic process
2.61 1.49e-02 GO:0044257 cellular protein catabolic process
2.63 1.98e-02 GO:0019941 modification-dependent protein catabolic process
2.23 2.13e-02 GO:0044265 cellular macromolecule catabolic process
2.61 2.22e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.50 2.24e-02 GO:0044267 cellular protein metabolic process
1.26 4.00e-02 GO:0044237 cellular metabolic process
2.44 4.82e-02 GO:0030163 protein catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.49e-03 GO:0005634 nucleus
1.14 2.65e-03 GO:0005622 intracellular
1.14 5.72e-03 GO:0044424 intracellular part
1.36 1.44e-02 GO:0032991 macromolecular complex
1.38 3.17e-02 GO:0043234 protein complex
1.15 4.14e-02 GO:0043229 intracellular organelle
1.15 4.92e-02 GO:0043226 organelle

Nothing significant found in function category.