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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 4.691

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_4909447	37.022	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr10_+_96305521	24.420	NM_018063	HELLS	helicase, lymphoid-specific
chr9_-_99180661	21.258	NM_153695	ZNF367	zinc finger protein 367
chr2_+_10262853	16.276	NM_001034	RRM2	ribonucleotide reductase M2
chr10_+_62538088	15.886	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr2_-_136633934	15.697		MCM6	minichromosome maintenance complex component 6
chr10_+_62538250	15.623		CDK1	cyclin-dependent kinase 1
chr2_+_10262694	15.063	NM_001165931	RRM2	ribonucleotide reductase M2
chr17_+_38444130	14.366		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr22_+_35796104	14.243	NM_006739	MCM5	minichromosome maintenance complex component 5
chr12_-_77459198	14.236	NM_203394	E2F7	E2F transcription factor 7
chr22_+_35796154	13.585		MCM5	minichromosome maintenance complex component 5
chr11_-_118966103	13.408		H2AFX	H2A histone family, member X
chr11_-_118966175	13.051	NM_002105	H2AFX	H2A histone family, member X
chr3_+_127317271	12.736		MCM2	minichromosome maintenance complex component 2
chr19_+_4910339	12.591	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr3_+_127317212	12.560	NM_004526	MCM2	minichromosome maintenance complex component 2
chr3_+_127317274	12.497		MCM2	minichromosome maintenance complex component 2
chr17_+_38444134	12.382	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr22_+_35796294	12.150		MCM5	minichromosome maintenance complex component 5
chr8_-_124408665	11.744		ATAD2	ATPase family, AAA domain containing 2
chr2_-_136634002	11.465	NM_005915	MCM6	minichromosome maintenance complex component 6
chr8_-_124408688	11.455	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr17_+_38444151	11.149		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr11_-_19263144	11.088		E2F8	E2F transcription factor 8
chr16_-_85722587	10.960	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr2_+_174219537	10.515	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr15_-_64673569	10.504	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr8_-_124408458	10.325		ATAD2	ATPase family, AAA domain containing 2
chr11_+_125495853	10.121		CHEK1	checkpoint kinase 1
chr14_-_55658205	10.094	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr7_-_99698993	9.945		MCM7	minichromosome maintenance complex component 7
chr7_-_99699030	9.811		MCM7	minichromosome maintenance complex component 7
chr7_-_99698916	9.752		MCM7	minichromosome maintenance complex component 7
chr20_+_25388328	9.598		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr6_+_31126340	9.084		TCF19	transcription factor 19
chr7_-_99699426	8.992	NM_005916	MCM7	minichromosome maintenance complex component 7
chr8_-_124408669	8.956		ATAD2	ATPase family, AAA domain containing 2
chr11_-_64851449	8.889		CDCA5	cell division cycle associated 5
chr1_+_212208918	8.845	NM_016448	DTL	denticleless homolog (Drosophila)
chr1_+_212209129	8.823		DTL	denticleless homolog (Drosophila)
chr20_+_25388320	8.817	NM_021067	GINS1	GINS complex subunit 1 (Psf1 homolog)
chr8_+_48873446	8.526		MCM4	minichromosome maintenance complex component 4
chr14_-_50154920	8.147		POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr14_-_50155097	8.058	NM_001197330 NM_001197331 NM_002692	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr20_-_5100443	8.056	NM_182649	PCNA	proliferating cell nuclear antigen
chr1_-_26232643	8.027	NM_203401	STMN1	stathmin 1
chr8_-_27695288	8.013	NM_018492	PBK	PDZ binding kinase
chr11_-_19262424	7.796	NM_024680	E2F8	E2F transcription factor 8
chr6_+_31126114	7.510	NM_001077511 NM_007109	TCF19	transcription factor 19
chr4_+_154265774	7.449	NM_001253861 NM_032117	MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr7_-_158497432	7.432	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr1_+_212209112	7.365		DTL	denticleless homolog (Drosophila)
chr15_+_41624891	7.133	NM_001243142 NM_001243143 NM_001243144 NM_016359 NM_018454	NUSAP1	nucleolar and spindle associated protein 1
chr8_+_26435339	7.080	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr15_-_41624760	7.012	NM_007280	OIP5	Opa interacting protein 5
chr13_+_34392254	6.979		RFC3	replication factor C (activator 1) 3, 38kDa
chr8_+_48873533	6.957		MCM4	minichromosome maintenance complex component 4
chr8_+_26435466	6.850		DPYSL2	dihydropyrimidinase-like 2
chr7_-_148581403	6.740	NM_001203247 NM_001203248 NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr19_-_10305536	6.697		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr19_-_10305600	6.691		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr1_-_26233367	6.687	NM_203399	STMN1	stathmin 1
chr7_-_148581297	6.679		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr8_-_95907423	6.599	NM_057749	CCNE2	cyclin E2
chr16_-_3030391	6.595		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr7_-_148581377	6.593		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr15_-_66648991	6.573	NM_017858	TIPIN	TIMELESS interacting protein
chr7_-_148581359	6.572		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr6_-_153304093	6.514	NM_012177	FBXO5	F-box protein 5
chr11_+_65029312	6.464	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr22_+_20105076	6.410		RANBP1	RAN binding protein 1
chr9_-_123639462	6.295		PHF19	PHD finger protein 19
chr10_+_13203547	6.238	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr16_-_3030473	6.198	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr19_-_10305645	6.081	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr16_+_88870185	6.052	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr15_+_41625052	6.051		NUSAP1	nucleolar and spindle associated protein 1
chr16_-_85722503	5.951		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr6_-_52149541	5.922	NM_002388	MCM3	minichromosome maintenance complex component 3
chr7_-_148581379	5.880		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr22_+_20105095	5.849		RANBP1	RAN binding protein 1
chr8_+_48873510	5.774		MCM4	minichromosome maintenance complex component 4
chr22_+_20105145	5.648		RANBP1	RAN binding protein 1
chr10_-_58121011	5.614		ZWINT	ZW10 interactor
chr10_-_58121019	5.585	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr9_-_35079520	5.462		FANCG	Fanconi anemia, complementation group G
chr6_-_52149516	5.453		MCM3	minichromosome maintenance complex component 3
chr22_+_19467413	5.375	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr22_+_20105068	5.318		RANBP1	RAN binding protein 1
chrX_+_24712063	5.300	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr1_-_23857711	5.298	NM_004091	E2F2	E2F transcription factor 2
chr9_-_123639566	5.168	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr3_+_44803280	5.165		KIF15	kinesin family member 15
chr11_+_125496123	5.036	NM_001274	CHEK1	checkpoint kinase 1
chr1_-_23857284	5.011		E2F2	E2F transcription factor 2
chr11_-_64851556	4.955	NM_080668	CDCA5	cell division cycle associated 5
chr1_-_47779651	4.934	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr13_+_73301980	4.926	NM_024808	BORA	bora, aurora kinase A activator
chr1_-_100598406	4.896	NM_194292	SASS6	spindle assembly 6 homolog (C. elegans)
chr7_+_94285620	4.855	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr6_-_52149472	4.775		MCM3	minichromosome maintenance complex component 3
chr15_+_41625152	4.705		NUSAP1	nucleolar and spindle associated protein 1
chr7_+_94285676	4.655	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr7_+_94285736	4.653		PEG10	paternally expressed 10
chr16_+_88870214	4.651		CDT1	chromatin licensing and DNA replication factor 1
chr9_-_35079751	4.619	NM_004629	FANCG	Fanconi anemia, complementation group G
chr3_+_44803208	4.589	NM_020242	KIF15	kinesin family member 15
chr22_+_19467467	4.472		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr3_-_48229800	4.459	NM_001789 NM_201567	CDC25A	cell division cycle 25 homolog A (S. pombe)
chr8_-_120868034	4.450	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr5_+_126112819	4.385	NM_001198557	LMNB1	lamin B1
chr6_+_24775640	4.303	NM_001251991	GMNN	geminin, DNA replication inhibitor
chr5_+_68485367	4.277	NM_022909	CENPH	centromere protein H
chr15_+_40987326	4.258	NM_001164270 NM_002875 NM_133487 NM_001164269	RAD51	RAD51 homolog (S. cerevisiae)
chr6_+_24775154	4.155	NM_001251989 NM_001251990 NM_015895	GMNN	geminin, DNA replication inhibitor
chr3_-_48229328	4.085		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr14_-_21572374	4.057
chr13_+_34392205	3.977	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chr10_-_129924467	3.930	NM_001145966 NM_002417	MKI67	antigen identified by monoclonal antibody Ki-67
chr5_-_79950348	3.913		DHFR	dihydrofolate reductase
chr15_+_91260575	3.905	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr5_-_146889618	3.903	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chr2_+_219433517	3.890	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_+_178230979	3.846	NM_018248	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr6_-_144329342	3.825	NM_001080952 NM_001080953 NM_001080954 NM_001080956 NM_002656 NM_006718	PLAGL1 HYMAI	pleiomorphic adenoma gene-like 1 hydatidiform mole associated and imprinted (non-protein coding)
chr9_-_98079856	3.784	NM_000136 NM_001243744	FANCC	Fanconi anemia, complementation group C
chr4_-_122744782	3.783		CCNA2	cyclin A2
chr11_+_64808375	3.723	NM_013299	SAC3D1	SAC3 domain containing 1
chr19_+_50887460	3.697		POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr15_+_32907690	3.666	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr1_+_38158189	3.619		CDCA8	cell division cycle associated 8
chr1_+_242011544	3.580		EXO1	exonuclease 1
chrX_+_48555124	3.573	NM_003173	SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr11_+_64808395	3.552		SAC3D1	SAC3 domain containing 1
chr1_-_26185847	3.534	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr5_-_79950307	3.532		DHFR	dihydrofolate reductase
chr1_+_38158176	3.507		CDCA8	cell division cycle associated 8
chr5_-_79950783	3.406	NM_000791	DHFR	dihydrofolate reductase
chr19_+_50887592	3.256	NM_002691	POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr10_+_102106958	3.252		SCD	stearoyl-CoA desaturase (delta-9-desaturase)
chr20_-_35724401	3.229	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr18_+_33877630	3.226	NM_025135	FHOD3	formin homology 2 domain containing 3
chrX_-_106243442	3.224	NM_001085354 NM_024657	MORC4	MORC family CW-type zinc finger 4
chr3_+_10068097	3.177	NM_001018115 NM_033084	FANCD2	Fanconi anemia, complementation group D2
chr5_-_37371078	3.144		NUP155	nucleoporin 155kDa
chr3_-_49893885	3.133	NM_005879	TRAIP	TRAF interacting protein
chr4_+_178231013	3.127		NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr16_+_58426297	3.067	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr13_+_114239047	3.062	NM_007111	TFDP1	transcription factor Dp-1
chr5_-_37371182	3.024	NM_153485	NUP155	nucleoporin 155kDa
chr1_+_242011471	3.020	NM_130398	EXO1	exonuclease 1
chr4_+_1873035	3.007	NM_001042424	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr1_-_54303933	2.990		TMEM48	transmembrane protein 48
chr8_+_31497267	2.984	NM_013962	NRG1	neuregulin 1
chr17_-_16256708	2.954	NM_181716	CENPV	centromere protein V
chr20_-_35724330	2.933		RBL1	retinoblastoma-like 1 (p107)
chr4_+_154265841	2.903		MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr5_+_36152221	2.852		SKP2	S-phase kinase-associated protein 2 (p45)
chrX_-_132092224	2.800		HS6ST2	heparan sulfate 6-O-sulfotransferase 2
chr10_+_94352960	2.794		KIF11	kinesin family member 11
chr10_+_14920781	2.785	NM_001193424 NM_001193426 NM_001193425 NM_001193427 NM_024670	SUV39H2	suppressor of variegation 3-9 homolog 2 (Drosophila)
chr15_+_40987387	2.757		RAD51	RAD51 homolog (S. cerevisiae)
chr10_+_94352873	2.717		KIF11	kinesin family member 11
chr9_+_139702389	2.700		C9orf86	chromosome 9 open reading frame 86
chr20_-_32274070	2.698		E2F1	E2F transcription factor 1
chr5_-_37370886	2.682	NM_004298	NUP155	nucleoporin 155kDa
chr3_+_10068139	2.667		FANCD2	Fanconi anemia, complementation group D2
chr12_-_12849120	2.661	NM_006143	GPR19	G protein-coupled receptor 19
chr5_+_36152142	2.647	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr1_-_26232890	2.645	NM_001145454 NM_005563	STMN1	stathmin 1
chr6_-_86388419	2.585		SNHG5	small nucleolar RNA host gene 5 (non-protein coding)
chr7_-_94285477	2.578	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chrX_+_106871739	2.561		PRPS1	phosphoribosyl pyrophosphate synthetase 1
chr6_+_135502521	2.557		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr7_-_94285426	2.542		SGCE	sarcoglycan, epsilon
chr2_+_178257371	2.541	NM_003659	AGPS	alkylglycerone phosphate synthase
chr1_-_24306739	2.532		SRSF10	serine/arginine-rich splicing factor 10
chr15_-_71184611	2.531	NM_020147	THAP10	THAP domain containing 10
chr10_-_25241504	2.525	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr5_+_93954352	2.516	NM_032290	ANKRD32	ankyrin repeat domain 32
chr21_-_34960937	2.506	NM_017613	DONSON	downstream neighbor of SON
chr2_+_17935124	2.502	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr4_+_71859391	2.499		DCK	deoxycytidine kinase
chr7_-_94285372	2.484		SGCE	sarcoglycan, epsilon
chr10_+_17271302	2.479		VIM	vimentin
chr9_-_98079506	2.478	NM_001243743	FANCC	Fanconi anemia, complementation group C
chr2_-_17935056	2.471		SMC6	structural maintenance of chromosomes 6
chr10_+_73723992	2.467	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr12_+_110906203	2.461	NM_013300	C12orf24	chromosome 12 open reading frame 24
chr2_+_132250500	2.444		LOC150776	sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr1_+_46713359	2.438	NM_001142548 NM_003579	RAD54L	RAD54-like (S. cerevisiae)
chr16_+_87636492	2.424	NM_020655	JPH3	junctophilin 3
chr10_-_75006963	2.419	NM_015190	DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr3_-_133380626	2.415	NM_007027	TOPBP1	topoisomerase (DNA) II binding protein 1
chr4_+_128802064	2.411	NM_001190801	PLK4	polo-like kinase 4
chr2_+_47630246	2.385	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr1_+_46049659	2.380	NM_001195193 NM_002482 NM_152298	NASP	nuclear autoantigenic sperm protein (histone-binding)
chr1_-_54304107	2.363	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr4_+_71859262	2.357	NM_000788	DCK	deoxycytidine kinase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.04	9.31e-45	GO:0007049	cell cycle
3.41	5.42e-39	GO:0022403	cell cycle phase
3.15	5.36e-38	GO:0022402	cell cycle process
3.35	5.07e-31	GO:0000278	mitotic cell cycle
2.01	1.99e-29	GO:0090304	nucleic acid metabolic process
1.87	4.74e-29	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.13	2.02e-26	GO:0006259	DNA metabolic process
1.60	2.51e-26	GO:0044260	cellular macromolecule metabolic process
3.38	1.94e-23	GO:0000279	M phase
1.70	1.91e-22	GO:0034641	cellular nitrogen compound metabolic process
1.67	5.40e-22	GO:0006807	nitrogen compound metabolic process
1.49	2.68e-21	GO:0043170	macromolecule metabolic process
2.83	8.96e-21	GO:0051276	chromosome organization
1.72	1.42e-19	GO:0071841	cellular component organization or biogenesis at cellular level
4.55	1.76e-19	GO:0006260	DNA replication
3.63	2.30e-19	GO:0051325	interphase
3.59	1.70e-18	GO:0051329	interphase of mitotic cell cycle
1.72	1.73e-18	GO:0071842	cellular component organization at cellular level
1.97	1.95e-18	GO:0006996	organelle organization
1.20	9.12e-18	GO:0009987	cellular process
1.58	1.65e-17	GO:0071840	cellular component organization or biogenesis
1.59	2.56e-17	GO:0016043	cellular component organization
3.49	1.37e-16	GO:0000280	nuclear division
3.49	1.37e-16	GO:0007067	mitosis
3.26	1.79e-16	GO:0006281	DNA repair
1.36	1.88e-16	GO:0044238	primary metabolic process
1.36	3.23e-16	GO:0044237	cellular metabolic process
3.39	7.22e-16	GO:0000087	M phase of mitotic cell cycle
3.38	8.84e-16	GO:0048285	organelle fission
2.74	1.10e-15	GO:0006974	response to DNA damage stimulus
2.51	1.45e-14	GO:0051726	regulation of cell cycle
3.08	2.88e-14	GO:0010564	regulation of cell cycle process
6.09	1.66e-13	GO:0006261	DNA-dependent DNA replication
4.19	2.63e-12	GO:0000082	G1/S transition of mitotic cell cycle
2.50	3.59e-12	GO:0016071	mRNA metabolic process
4.21	4.95e-12	GO:0006310	DNA recombination
3.05	5.79e-12	GO:0008380	RNA splicing
1.28	7.22e-12	GO:0008152	metabolic process
3.48	8.08e-12	GO:0000075	cell cycle checkpoint
2.78	8.17e-12	GO:0006397	mRNA processing
3.42	9.66e-12	GO:0071156	regulation of cell cycle arrest
2.87	1.03e-11	GO:0051301	cell division
2.32	1.67e-11	GO:0006396	RNA processing
2.12	4.20e-11	GO:0033554	cellular response to stress
4.39	1.60e-10	GO:0051320	S phase
4.34	5.37e-10	GO:0000084	S phase of mitotic cell cycle
8.62	5.76e-10	GO:0006271	DNA strand elongation involved in DNA replication
3.31	1.33e-09	GO:0000375	RNA splicing, via transesterification reactions
1.84	2.06e-09	GO:0044085	cellular component biogenesis
8.05	2.80e-09	GO:0022616	DNA strand elongation
1.65	1.20e-08	GO:0016070	RNA metabolic process
4.00	3.04e-08	GO:0051321	meiotic cell cycle
3.17	3.51e-08	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.17	3.51e-08	GO:0000398	nuclear mRNA splicing, via spliceosome
1.84	4.64e-08	GO:0022607	cellular component assembly
3.91	1.25e-07	GO:0007126	meiosis
3.91	1.25e-07	GO:0051327	M phase of meiotic cell cycle
4.00	1.43e-07	GO:0007059	chromosome segregation
2.49	1.49e-07	GO:0034622	cellular macromolecular complex assembly
2.29	1.87e-07	GO:0006325	chromatin organization
2.02	2.56e-07	GO:0065003	macromolecular complex assembly
1.98	3.02e-07	GO:0071844	cellular component assembly at cellular level
11.84	4.07e-07	GO:0071897	DNA biosynthetic process
1.56	7.71e-07	GO:0010467	gene expression
3.26	1.39e-06	GO:0071103	DNA conformation change
1.59	1.46e-06	GO:0034645	cellular macromolecule biosynthetic process
5.29	1.50e-06	GO:0051053	negative regulation of DNA metabolic process
1.47	1.97e-06	GO:0044249	cellular biosynthetic process
3.68	2.47e-06	GO:0051028	mRNA transport
8.52	2.54e-06	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
1.57	3.59e-06	GO:0009059	macromolecule biosynthetic process
3.49	4.83e-06	GO:0050657	nucleic acid transport
3.49	4.83e-06	GO:0050658	RNA transport
3.49	4.83e-06	GO:0051236	establishment of RNA localization
3.55	6.04e-06	GO:0071824	protein-DNA complex subunit organization
3.36	7.04e-06	GO:0006323	DNA packaging
3.62	7.46e-06	GO:0065004	protein-DNA complex assembly
3.26	8.03e-06	GO:0006333	chromatin assembly or disassembly
3.38	1.10e-05	GO:0006403	RNA localization
7.75	1.14e-05	GO:0006270	DNA-dependent DNA replication initiation
3.09	1.82e-05	GO:0000226	microtubule cytoskeleton organization
1.42	2.17e-05	GO:0009058	biosynthetic process
5.61	3.84e-05	GO:0008156	negative regulation of DNA replication
3.11	4.62e-05	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
2.24	5.94e-05	GO:0016568	chromatin modification
3.51	1.02e-04	GO:0031497	chromatin assembly
1.76	1.03e-04	GO:0043933	macromolecular complex subunit organization
7.89	1.82e-04	GO:0007062	sister chromatid cohesion
5.37	2.19e-04	GO:0051318	G1 phase
1.99	2.69e-04	GO:0034621	cellular macromolecular complex subunit organization
3.34	2.87e-04	GO:0034728	nucleosome organization
4.64	2.93e-04	GO:0007051	spindle organization
6.79	3.01e-04	GO:0090329	regulation of DNA-dependent DNA replication
7.48	3.60e-04	GO:0032201	telomere maintenance via semi-conservative replication
4.84	3.81e-04	GO:0000819	sister chromatid segregation
4.06	4.81e-04	GO:0031124	mRNA 3'-end processing
6.51	5.21e-04	GO:0031055	chromatin remodeling at centromere
5.43	5.48e-04	GO:0000080	G1 phase of mitotic cell cycle
7.10	6.75e-04	GO:0000722	telomere maintenance via recombination
7.10	6.75e-04	GO:0006298	mismatch repair
7.10	6.75e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
3.40	7.07e-04	GO:0006334	nucleosome assembly
3.64	7.24e-04	GO:0000216	M/G1 transition of mitotic cell cycle
2.88	7.43e-04	GO:0051052	regulation of DNA metabolic process
4.85	9.66e-04	GO:0000070	mitotic sister chromatid segregation
3.55	1.13e-03	GO:0006275	regulation of DNA replication
4.74	1.36e-03	GO:0006369	termination of RNA polymerase II transcription
4.44	1.39e-03	GO:0000723	telomere maintenance
6.01	1.41e-03	GO:0006312	mitotic recombination
3.60	1.74e-03	GO:0031123	RNA 3'-end processing
4.35	1.87e-03	GO:0032200	telomere organization
3.02	2.15e-03	GO:0031570	DNA integrity checkpoint
4.06	2.28e-03	GO:0007127	meiosis I
6.73	4.85e-03	GO:0051225	spindle assembly
3.85	4.91e-03	GO:0006406	mRNA export from nucleus
3.50	5.20e-03	GO:0006338	chromatin remodeling
1.87	5.65e-03	GO:0070271	protein complex biogenesis
10.65	7.22e-03	GO:0000731	DNA synthesis involved in DNA repair
1.17	7.31e-03	GO:0050794	regulation of cellular process
5.68	8.62e-03	GO:0043486	histone exchange
3.25	9.05e-03	GO:0000236	mitotic prometaphase
7.10	1.11e-02	GO:0006297	nucleotide-excision repair, DNA gap filling
3.45	1.24e-02	GO:0006302	double-strand break repair
2.17	1.25e-02	GO:0007017	microtubule-based process
6.09	1.36e-02	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
6.09	1.36e-02	GO:0016444	somatic cell DNA recombination
2.13	1.83e-02	GO:0007346	regulation of mitotic cell cycle
1.82	1.96e-02	GO:0006461	protein complex assembly
5.81	2.15e-02	GO:0006336	DNA replication-independent nucleosome assembly
5.81	2.15e-02	GO:0034080	CenH3-containing nucleosome assembly at centromere
5.81	2.15e-02	GO:0034724	DNA replication-independent nucleosome organization
3.44	2.39e-02	GO:0006405	RNA export from nucleus
2.22	2.40e-02	GO:0009314	response to radiation
1.15	2.48e-02	GO:0050789	regulation of biological process
5.07	2.85e-02	GO:0043044	ATP-dependent chromatin remodeling
3.12	3.02e-02	GO:0051168	nuclear export
3.55	3.03e-02	GO:0009411	response to UV
3.34	3.60e-02	GO:0006473	protein acetylation
1.14	4.62e-02	GO:0065007	biological regulation
8.52	4.79e-02	GO:0006301	postreplication repair

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.32	1.32e-50	GO:0044428	nuclear part
2.35	6.90e-43	GO:0031981	nuclear lumen
1.60	5.61e-41	GO:0005634	nucleus
2.53	1.48e-37	GO:0005654	nucleoplasm
2.10	1.90e-37	GO:0070013	intracellular organelle lumen
2.06	8.37e-37	GO:0031974	membrane-enclosed lumen
2.07	1.54e-36	GO:0043233	organelle lumen
1.30	1.83e-30	GO:0043229	intracellular organelle
1.30	1.90e-30	GO:0043226	organelle
1.33	1.90e-29	GO:0043227	membrane-bounded organelle
1.33	2.52e-29	GO:0043231	intracellular membrane-bounded organelle
1.22	1.44e-27	GO:0005622	intracellular
1.23	1.61e-27	GO:0044424	intracellular part
1.50	1.76e-27	GO:0044446	intracellular organelle part
1.49	6.31e-27	GO:0044422	organelle part
2.87	4.59e-21	GO:0005694	chromosome
2.88	1.83e-17	GO:0044427	chromosomal part
1.50	2.57e-14	GO:0032991	macromolecular complex
2.31	2.93e-14	GO:0044451	nucleoplasm part
1.54	3.28e-12	GO:0043228	non-membrane-bounded organelle
1.54	3.28e-12	GO:0043232	intracellular non-membrane-bounded organelle
3.25	8.83e-11	GO:0000228	nuclear chromosome
1.44	8.11e-09	GO:0043234	protein complex
3.26	1.42e-08	GO:0044454	nuclear chromosome part
2.84	3.81e-08	GO:0000785	chromatin
2.79	2.87e-07	GO:0016604	nuclear body
3.27	7.49e-07	GO:0000793	condensed chromosome
2.86	3.61e-06	GO:0005819	spindle
5.76	4.43e-06	GO:0005657	replication fork
3.00	1.96e-05	GO:0000775	chromosome, centromeric region
12.43	2.74e-05	GO:0042555	MCM complex
1.92	1.04e-04	GO:0030529	ribonucleoprotein complex
1.87	4.47e-04	GO:0005730	nucleolus
4.52	4.60e-04	GO:0000792	heterochromatin
1.05	5.97e-04	GO:0044464	cell part
1.05	6.14e-04	GO:0005623	cell
2.76	8.47e-04	GO:0005681	spliceosomal complex
1.72	8.51e-04	GO:0015630	microtubule cytoskeleton
6.73	8.67e-04	GO:0031519	PcG protein complex
2.02	1.79e-03	GO:0005815	microtubule organizing center
3.81	2.15e-03	GO:0016605	PML body
9.47	3.63e-03	GO:0005721	centromeric heterochromatin
9.47	3.63e-03	GO:0035098	ESC/E(Z) complex
3.44	4.27e-03	GO:0000922	spindle pole
3.62	8.39e-03	GO:0000794	condensed nuclear chromosome
3.14	8.61e-03	GO:0000779	condensed chromosome, centromeric region
2.95	2.04e-02	GO:0000790	nuclear chromatin
3.31	2.40e-02	GO:0000123	histone acetyltransferase complex
2.08	2.87e-02	GO:0005813	centrosome
7.10	3.32e-02	GO:0032300	mismatch repair complex
5.17	3.35e-02	GO:0043596	nuclear replication fork
5.85	3.79e-02	GO:0030894	replisome
5.85	3.79e-02	GO:0043601	nuclear replisome
2.00	4.88e-02	GO:0005635	nuclear envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.34	1.21e-20	GO:0005515	protein binding
1.16	2.74e-15	GO:0005488	binding
1.45	2.41e-10	GO:0003676	nucleic acid binding
1.55	4.61e-10	GO:0000166	nucleotide binding
1.44	4.83e-06	GO:0003677	DNA binding
2.60	1.48e-04	GO:0003682	chromatin binding
4.44	3.46e-04	GO:0003684	damaged DNA binding
3.65	3.48e-04	GO:0042393	histone binding
1.46	6.13e-04	GO:0030554	adenyl nucleotide binding
1.46	7.16e-04	GO:0032559	adenyl ribonucleotide binding
8.12	7.32e-04	GO:0030983	mismatched DNA binding
1.40	1.16e-03	GO:0017076	purine nucleotide binding
2.46	1.17e-03	GO:0043566	structure-specific DNA binding
1.64	1.20e-03	GO:0003723	RNA binding
1.40	1.26e-03	GO:0032553	ribonucleotide binding
1.40	1.26e-03	GO:0032555	purine ribonucleotide binding
5.39	1.30e-03	GO:0034061	DNA polymerase activity
2.74	1.37e-03	GO:0003690	double-stranded DNA binding
1.43	3.11e-03	GO:0005524	ATP binding
3.61	3.13e-03	GO:0008094	DNA-dependent ATPase activity
5.46	3.27e-03	GO:0003887	DNA-directed DNA polymerase activity
1.37	5.76e-03	GO:0035639	purine ribonucleoside triphosphate binding
11.84	5.86e-03	GO:0032135	DNA insertion or deletion binding
3.14	1.20e-02	GO:0003729	mRNA binding
3.49	1.81e-02	GO:0003697	single-stranded DNA binding
4.11	2.50e-02	GO:0019205	nucleobase, nucleoside, nucleotide kinase activity
1.94	3.29e-02	GO:0008134	transcription factor binding
7.10	4.64e-02	GO:0000217	DNA secondary structure binding