Motif ID: ELF1,2,4.p2

Z-value: 1.528


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF4chrX_-_1292444220.791.7e-07Click!
ELF2chr4_-_140005464-0.301.1e-01Click!
ELF1chr13_-_41593491-0.077.3e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_137801166 3.122 EGR1
early growth response 1
chr17_+_2699731 3.118 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr6_+_80714321 3.076 NM_001166691
NM_003318
TTK

TTK protein kinase

chrX_-_153775427 3.060 G6PD
glucose-6-phosphate dehydrogenase
chr6_+_80714389 2.766 TTK
TTK protein kinase
chr13_-_60738078 2.725 NM_001042517
DIAPH3
diaphanous homolog 3 (Drosophila)
chr8_+_22462267 2.636 KIAA1967
KIAA1967
chr11_-_46722139 2.482 ARHGAP1
Rho GTPase activating protein 1
chr1_+_169764174 2.418 C1orf112
chromosome 1 open reading frame 112
chr18_+_56338783 2.302 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr15_+_38544119 2.292 SPRED1
sprouty-related, EVH1 domain containing 1
chr5_+_137801178 2.225 NM_001964
EGR1
early growth response 1
chr7_+_40174480 2.181 NM_001193311
NM_001193312
NM_001193313
NM_024728
C7orf10



chromosome 7 open reading frame 10



chr12_-_123214882 2.151 NM_032554
HCAR1
hydroxycarboxylic acid receptor 1
chr13_-_60737899 2.131 DIAPH3
diaphanous homolog 3 (Drosophila)
chr7_-_97601654 2.114


chr5_+_892950 2.105 NM_001166260
NM_004237
TRIP13

thyroid hormone receptor interactor 13

chr8_+_26371461 2.104 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr19_-_51845377 2.066 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr11_-_46722160 2.045 ARHGAP1
Rho GTPase activating protein 1
chr5_-_171615095 2.041 STK10
serine/threonine kinase 10
chr19_-_4723814 2.011 NM_139159
DPP9
dipeptidyl-peptidase 9
chr22_+_38035683 1.965 NM_018957
SH3BP1
SH3-domain binding protein 1
chr12_+_53443834 1.964 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr8_+_28559143 1.958 NM_001440
EXTL3
exostoses (multiple)-like 3
chr19_-_51456159 1.953 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr2_-_65593866 1.938 NM_001128210
SPRED2
sprouty-related, EVH1 domain containing 2
chr18_+_56338678 1.921 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr11_-_64851449 1.902 CDCA5
cell division cycle associated 5
chr11_-_64851556 1.885 NM_080668
CDCA5
cell division cycle associated 5
chrX_+_64887534 1.865 MSN
moesin
chrX_+_64887593 1.853 MSN
moesin
chr14_-_54955714 1.850 NM_004124
GMFB
glia maturation factor, beta
chr19_-_4723755 1.844 DPP9
dipeptidyl-peptidase 9
chr14_+_65171243 1.809 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_-_36019194 1.807 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr14_-_100842637 1.797 WARS
tryptophanyl-tRNA synthetase
chr19_-_14247267 1.791 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr4_+_1723233 1.789 TACC3
transforming, acidic coiled-coil containing protein 3
chr19_-_4723791 1.773 DPP9
dipeptidyl-peptidase 9
chr14_-_54955664 1.771 GMFB
glia maturation factor, beta
chrX_+_64887510 1.768 NM_002444
MSN
moesin
chr11_-_46722115 1.748 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr11_+_65343498 1.713 NM_001099409
EHBP1L1
EH domain binding protein 1-like 1
chr1_+_43824598 1.685 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr10_+_27443752 1.683 NM_001172303
NM_001172304
NM_032844
MASTL


microtubule associated serine/threonine kinase-like


chr22_+_31478845 1.661 NM_001207017
SMTN
smoothelin
chr8_+_28559010 1.655 EXTL3
exostoses (multiple)-like 3
chr19_-_14247400 1.626 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_+_143078457 1.623 ZYX
zyxin
chr7_+_143078399 1.620 ZYX
zyxin
chr7_+_143078395 1.589 ZYX
zyxin
chr12_-_124068864 1.571


chr1_+_209859524 1.571 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr6_-_42419782 1.565 NM_033502
TRERF1
transcriptional regulating factor 1
chr7_+_134464161 1.559 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr7_+_143078447 1.543 ZYX
zyxin
chr7_+_143078444 1.536 ZYX
zyxin
chr1_+_169764549 1.536 NM_018186
C1orf112
chromosome 1 open reading frame 112
chr15_+_74833517 1.534 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr4_-_10023094 1.530 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr15_-_73661141 1.527 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chrX_-_153775774 1.526 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr22_+_38035718 1.509 SH3BP1
SH3-domain binding protein 1
chr17_-_8113862 1.508 NM_004217
AURKB
aurora kinase B
chr1_-_154946830 1.493 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr6_-_153304590 1.478 NM_001142522
FBXO5
F-box protein 5
chr6_-_167571315 1.471 NM_005299
GPR31
G protein-coupled receptor 31
chr2_+_31456879 1.465 NM_014600
EHD3
EH-domain containing 3
chr16_+_31483066 1.462 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr2_-_74667553 1.459 NM_001015056
NM_033046
RTKN

rhotekin

chr1_-_154946859 1.456 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr1_+_32687970 1.447 NM_003757
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32688053 1.441 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_169337193 1.434 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr1_+_32688013 1.428 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr5_+_87564729 1.427 LOC100505894
uncharacterized LOC100505894
chr1_+_32688010 1.422 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_84609941 1.403 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr21_-_38639593 1.351 DSCR3
Down syndrome critical region gene 3
chr1_-_43855448 1.350 MED8
mediator complex subunit 8
chr1_+_151032150 1.338 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_-_100842676 1.337 NM_173701
NM_213645
WARS

tryptophanyl-tRNA synthetase

chr7_+_143078608 1.332 ZYX
zyxin
chr6_-_131291480 1.331 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_-_42744318 1.316 NM_020707
HHATL
hedgehog acyltransferase-like
chr6_-_131384387 1.316 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chr17_-_43510204 1.316 ARHGAP27
Rho GTPase activating protein 27
chr2_-_45838383 1.305 NM_018079
SRBD1
S1 RNA binding domain 1
chr5_-_39219578 1.289 NM_001465
NM_199335
FYB

FYN binding protein

chr18_-_21166440 1.288 NM_000271
NPC1
Niemann-Pick disease, type C1
chr2_+_210867355 1.287 NM_199229
RPE
ribulose-5-phosphate-3-epimerase
chrX_-_15872905 1.277


chr1_+_222886655 1.274 BROX
BRO1 domain and CAAX motif containing
chr11_+_61560401 1.274 FEN1
flap structure-specific endonuclease 1
chr11_-_7694685 1.270 NM_016229
CYB5R2
cytochrome b5 reductase 2
chrX_-_15872921 1.266 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_154946801 1.264 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr16_+_50308020 1.254 ADCY7
adenylate cyclase 7
chr18_-_21166378 1.249 NPC1
Niemann-Pick disease, type C1
chr2_+_234160216 1.237 NM_001190266
NM_001190267
NM_017974
NM_030803
NM_198890
ATG16L1




ATG16 autophagy related 16-like 1 (S. cerevisiae)




chr2_-_192015733 1.215 STAT4
signal transducer and activator of transcription 4
chr2_+_210867321 1.213 NM_006916
RPE
ribulose-5-phosphate-3-epimerase
chr14_+_55034329 1.212 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr16_+_30194925 1.209 CORO1A
coronin, actin binding protein, 1A
chr2_+_234160345 1.206 ATG16L1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr17_+_78389215 1.202 ENDOV
endonuclease V
chr1_-_28969516 1.194 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr11_+_63606598 1.182 MARK2
MAP/microtubule affinity-regulating kinase 2
chr22_+_38142245 1.178 TRIOBP
TRIO and F-actin binding protein
chr1_+_6086369 1.178 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_5013618 1.173 RNF216P1
ring finger protein 216 pseudogene 1
chr12_-_52779362 1.168 NM_033045
KRT84
keratin 84
chr21_-_16437125 1.164 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr7_+_134464417 1.164 CALD1
caldesmon 1
chr12_-_6961044 1.162 CDCA3
cell division cycle associated 3
chr1_-_118472178 1.153 GDAP2
ganglioside induced differentiation associated protein 2
chr6_-_131384321 1.149 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_-_192015934 1.147 NM_003151
STAT4
signal transducer and activator of transcription 4
chr1_-_20812727 1.146 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_99698278 1.144 NM_182776
MCM7
minichromosome maintenance complex component 7
chr14_+_65171149 1.136 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_+_93447702 1.134 CHD2
chromodomain helicase DNA binding protein 2
chr1_+_16083132 1.126 FBLIM1
filamin binding LIM protein 1
chr7_+_143078358 1.124 NM_001010972
NM_003461
ZYX

zyxin

chr9_-_88969256 1.121 ZCCHC6
zinc finger, CCHC domain containing 6
chr20_+_37555055 1.121 FAM83D
family with sequence similarity 83, member D
chr13_+_49280619 1.111 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr11_+_63606346 1.106 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr20_+_37554954 1.101 NM_030919
FAM83D
family with sequence similarity 83, member D
chr1_+_156863522 1.087 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr10_+_26986557 1.081 NM_014317
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr2_-_192015751 1.072 STAT4
signal transducer and activator of transcription 4
chr1_+_150480486 1.066 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr12_-_21654484 1.065 NM_002907
NM_032941
RECQL

RecQ protein-like (DNA helicase Q1-like)

chr7_+_39663257 1.064 RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr18_-_13726433 1.046 FAM210A
family with sequence similarity 210, member A
chr10_-_118680978 1.044 KIAA1598
KIAA1598
chr12_-_21654206 1.043 RECQL
RecQ protein-like (DNA helicase Q1-like)
chr12_-_54653369 1.040 NM_001127321
CBX5
chromobox homolog 5
chr19_-_49243836 1.027 NM_017805
RASIP1
Ras interacting protein 1
chr1_+_150480584 1.025 ECM1
extracellular matrix protein 1
chr3_-_12800739 1.022 NM_018306
TMEM40
transmembrane protein 40
chr9_-_95432269 1.019 IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr18_+_56338818 1.018 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr6_-_42185603 1.014 NM_018141
MRPS10
mitochondrial ribosomal protein S10
chr1_-_38273823 1.014 YRDC
yrdC domain containing (E. coli)
chr6_-_42185599 1.013 MRPS10
mitochondrial ribosomal protein S10
chr5_+_82373316 1.012 NM_003401
NM_022406
NM_022550
XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr17_-_43510279 1.010 NM_174919
ARHGAP27
Rho GTPase activating protein 27
chr12_+_96588254 1.010 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr14_-_100842623 1.009 WARS
tryptophanyl-tRNA synthetase
chr12_+_96588000 1.008 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chrX_-_131351917 1.006 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr12_+_133287382 0.997 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr1_-_231114580 0.995 TTC13
tetratricopeptide repeat domain 13
chr17_-_4851688 0.994 PFN1
profilin 1
chr12_+_12509947 0.994 NM_058169
LOH12CR1
loss of heterozygosity, 12, chromosomal region 1
chr6_-_42185586 0.991 MRPS10
mitochondrial ribosomal protein S10
chr3_-_139258373 0.991 RBP1
retinol binding protein 1, cellular
chr4_+_177241109 0.981 SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_+_155178489 0.978 NM_002455
NM_198883
MTX1

metaxin 1

chr8_-_23261591 0.978 LOXL2
lysyl oxidase-like 2
chr1_+_40506449 0.974 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr8_-_23261626 0.973 LOXL2
lysyl oxidase-like 2
chr1_-_52499432 0.971 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr2_-_190044330 0.968 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_-_192015706 0.967 STAT4
signal transducer and activator of transcription 4
chrX_+_69509878 0.956 NM_012310
KIF4A
kinesin family member 4A
chr12_-_33049664 0.955 NM_001005242
NM_004572
PKP2

plakophilin 2

chr2_-_37193609 0.953 NM_003162
STRN
striatin, calmodulin binding protein
chr19_+_47105327 0.951 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr2_-_242626197 0.951 DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr7_+_87505737 0.950 DBF4
DBF4 homolog (S. cerevisiae)
chr22_+_38302296 0.949 MICALL1
MICAL-like 1
chr1_-_109825767 0.949 NM_001005290
NM_001032291
NM_032636
PSRC1


proline/serine-rich coiled-coil 1


chr18_-_13726582 0.946 NM_001098801
NM_152352
FAM210A

family with sequence similarity 210, member A

chr19_-_47217576 0.944 NM_001079882
PRKD2
protein kinase D2
chr17_-_41277304 0.943 BRCA1
breast cancer 1, early onset
chr8_-_130951896 0.942 FAM49B
family with sequence similarity 49, member B
chr1_+_110091249 0.942 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr2_-_80530943 0.940 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr18_+_657461 0.939 NM_001071
TYMS
thymidylate synthetase
chrX_-_8700132 0.938 KAL1
Kallmann syndrome 1 sequence
chr5_+_110074740 0.937 NM_138773
SLC25A46
solute carrier family 25, member 46
chr6_-_42185597 0.936 MRPS10
mitochondrial ribosomal protein S10
chr19_+_41257086 0.934 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr7_+_99156263 0.933 ZNF655
zinc finger protein 655
chr11_+_63606535 0.933 MARK2
MAP/microtubule affinity-regulating kinase 2
chr5_-_171615239 0.933 STK10
serine/threonine kinase 10
chr19_+_3224734 0.930 CELF5
CUGBP, Elav-like family member 5
chr3_-_108308460 0.929 NM_020890
KIAA1524
KIAA1524
chr20_-_48532036 0.927 SPATA2
spermatogenesis associated 2
chr6_+_34204647 0.926 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr1_+_15736422 0.923 EFHD2
EF-hand domain family, member D2
chr19_-_14887623 0.921 EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr9_-_35103144 0.920 NM_013442
STOML2
stomatin (EPB72)-like 2
chr20_+_30326903 0.919 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr19_+_41256758 0.919 NM_004596
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr11_+_61560352 0.917 FEN1
flap structure-specific endonuclease 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.31 2.52e-32 GO:0044260 cellular macromolecule metabolic process
1.26 1.26e-26 GO:0043170 macromolecule metabolic process
1.36 6.49e-24 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 1.16e-22 GO:0044238 primary metabolic process
1.39 3.45e-21 GO:0090304 nucleic acid metabolic process
1.20 6.14e-21 GO:0044237 cellular metabolic process
1.31 4.95e-20 GO:0034641 cellular nitrogen compound metabolic process
1.10 2.87e-19 GO:0009987 cellular process
1.29 6.76e-19 GO:0006807 nitrogen compound metabolic process
1.38 4.22e-16 GO:0010467 gene expression
1.16 5.63e-16 GO:0008152 metabolic process
1.36 6.40e-13 GO:0016070 RNA metabolic process
1.29 8.08e-13 GO:0044267 cellular protein metabolic process
1.61 8.31e-13 GO:0006396 RNA processing
1.65 8.82e-13 GO:0000278 mitotic cell cycle
1.36 1.34e-12 GO:0009059 macromolecule biosynthetic process
1.36 3.25e-12 GO:0034645 cellular macromolecule biosynthetic process
1.66 3.39e-12 GO:0016071 mRNA metabolic process
1.26 3.39e-11 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 5.46e-11 GO:0071840 cellular component organization or biogenesis
1.44 2.31e-10 GO:0007049 cell cycle
1.54 2.60e-10 GO:0022403 cell cycle phase
1.72 2.83e-10 GO:0006397 mRNA processing
1.49 4.06e-10 GO:0022402 cell cycle process
1.79 1.95e-09 GO:0008380 RNA splicing
1.21 6.68e-09 GO:0016043 cellular component organization
1.22 1.00e-08 GO:0019538 protein metabolic process
1.24 1.97e-08 GO:0071842 cellular component organization at cellular level
1.74 2.78e-08 GO:0006412 translation
1.24 2.91e-08 GO:0009058 biosynthetic process
1.46 2.93e-08 GO:0046907 intracellular transport
1.23 3.05e-07 GO:0044249 cellular biosynthetic process
1.53 4.12e-07 GO:0044265 cellular macromolecule catabolic process
1.32 6.38e-07 GO:0033036 macromolecule localization
1.29 7.60e-07 GO:0006996 organelle organization
1.85 1.09e-06 GO:0022613 ribonucleoprotein complex biogenesis
1.32 1.37e-06 GO:0051641 cellular localization
1.21 1.98e-06 GO:0048518 positive regulation of biological process
1.67 2.30e-06 GO:0048285 organelle fission
1.66 2.91e-06 GO:0051325 interphase
1.78 3.38e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.66 3.90e-06 GO:0051329 interphase of mitotic cell cycle
1.80 4.23e-06 GO:0071843 cellular component biogenesis at cellular level
1.22 4.35e-06 GO:0048522 positive regulation of cellular process
1.47 5.26e-06 GO:0006259 DNA metabolic process
1.45 5.98e-06 GO:0009057 macromolecule catabolic process
1.59 7.90e-06 GO:0030163 protein catabolic process
1.65 8.46e-06 GO:0000087 M phase of mitotic cell cycle
1.80 9.97e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.80 9.97e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
1.75 1.10e-05 GO:0071156 regulation of cell cycle arrest
1.65 1.16e-05 GO:0000280 nuclear division
1.65 1.16e-05 GO:0007067 mitosis
1.33 1.26e-05 GO:0051649 establishment of localization in cell
1.37 1.35e-05 GO:0015031 protein transport
1.37 1.39e-05 GO:0045184 establishment of protein localization
1.33 1.73e-05 GO:0008104 protein localization
1.31 1.82e-05 GO:0044085 cellular component biogenesis
1.59 3.33e-05 GO:0044257 cellular protein catabolic process
1.76 4.53e-05 GO:0000375 RNA splicing, via transesterification reactions
1.36 4.65e-05 GO:0016265 death
2.22 4.69e-05 GO:0000216 M/G1 transition of mitotic cell cycle
2.02 4.94e-05 GO:0051320 S phase
1.57 5.70e-05 GO:0051301 cell division
1.36 6.12e-05 GO:0033554 cellular response to stress
2.02 6.70e-05 GO:0000084 S phase of mitotic cell cycle
1.35 6.84e-05 GO:0008219 cell death
1.89 7.30e-05 GO:0000082 G1/S transition of mitotic cell cycle
1.72 8.01e-05 GO:0000075 cell cycle checkpoint
1.77 1.04e-04 GO:0006260 DNA replication
1.38 1.42e-04 GO:0006915 apoptosis
1.57 1.43e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
1.57 1.55e-04 GO:0043632 modification-dependent macromolecule catabolic process
1.55 1.84e-04 GO:0010564 regulation of cell cycle process
1.45 2.03e-04 GO:0006974 response to DNA damage stimulus
1.57 2.16e-04 GO:0006511 ubiquitin-dependent protein catabolic process
1.37 2.20e-04 GO:0012501 programmed cell death
1.55 3.92e-04 GO:0019941 modification-dependent protein catabolic process
1.49 4.87e-04 GO:0016032 viral reproduction
1.21 5.90e-04 GO:0043412 macromolecule modification
1.61 6.41e-04 GO:0016567 protein ubiquitination
1.43 7.10e-04 GO:0070727 cellular macromolecule localization
1.43 7.52e-04 GO:0034613 cellular protein localization
1.22 7.66e-04 GO:0006464 protein modification process
1.53 8.11e-04 GO:0070647 protein modification by small protein conjugation or removal
1.58 1.05e-03 GO:0032446 protein modification by small protein conjugation
1.48 1.20e-03 GO:0006886 intracellular protein transport
1.34 1.34e-03 GO:0016192 vesicle-mediated transport
1.28 1.69e-03 GO:0051246 regulation of protein metabolic process
1.37 1.89e-03 GO:0051726 regulation of cell cycle
1.08 2.14e-03 GO:0050789 regulation of biological process
1.92 2.15e-03 GO:0007059 chromosome segregation
1.32 2.48e-03 GO:0043933 macromolecular complex subunit organization
1.26 2.99e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.28 3.26e-03 GO:0032268 regulation of cellular protein metabolic process
2.02 3.53e-03 GO:0051168 nuclear export
1.25 3.89e-03 GO:0009893 positive regulation of metabolic process
1.82 3.94e-03 GO:0006403 RNA localization
1.26 4.75e-03 GO:0031325 positive regulation of cellular metabolic process
2.02 4.79e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.93 5.00e-03 GO:0051340 regulation of ligase activity
1.08 5.65e-03 GO:0065007 biological regulation
1.77 5.67e-03 GO:0048193 Golgi vesicle transport
1.97 5.81e-03 GO:0071826 ribonucleoprotein complex subunit organization
2.11 6.01e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.43 6.94e-03 GO:0000279 M phase
1.81 7.10e-03 GO:0050657 nucleic acid transport
1.81 7.10e-03 GO:0050658 RNA transport
1.81 7.10e-03 GO:0051236 establishment of RNA localization
1.99 7.21e-03 GO:0022618 ribonucleoprotein complex assembly
1.39 7.24e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.70 7.52e-03 GO:0010498 proteasomal protein catabolic process
1.70 7.52e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.40 7.70e-03 GO:0007010 cytoskeleton organization
1.93 9.18e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
1.25 1.13e-02 GO:0044248 cellular catabolic process
1.49 1.20e-02 GO:0031401 positive regulation of protein modification process
2.02 1.20e-02 GO:0000209 protein polyubiquitination
1.26 1.22e-02 GO:0022607 cellular component assembly
2.08 1.28e-02 GO:0006405 RNA export from nucleus
1.99 1.33e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.72 1.36e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
1.52 1.62e-02 GO:0034660 ncRNA metabolic process
1.08 1.64e-02 GO:0050794 regulation of cellular process
1.92 1.69e-02 GO:0018196 peptidyl-asparagine modification
1.92 1.69e-02 GO:0018279 protein N-linked glycosylation via asparagine
1.50 1.76e-02 GO:0006366 transcription from RNA polymerase II promoter
1.77 1.79e-02 GO:0042254 ribosome biogenesis
1.76 1.80e-02 GO:0007093 mitotic cell cycle checkpoint
1.32 1.96e-02 GO:0065003 macromolecular complex assembly
2.02 2.22e-02 GO:0051352 negative regulation of ligase activity
2.02 2.22e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.37 2.73e-02 GO:0034621 cellular macromolecular complex subunit organization
1.79 3.09e-02 GO:0051028 mRNA transport
1.92 3.10e-02 GO:0051351 positive regulation of ligase activity
1.63 3.33e-02 GO:0043687 post-translational protein modification
1.33 4.04e-02 GO:0042060 wound healing
1.89 4.45e-02 GO:0000236 mitotic prometaphase

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 3.00e-34 GO:0044424 intracellular part
1.12 1.28e-32 GO:0005622 intracellular
1.17 5.89e-28 GO:0005737 cytoplasm
1.42 6.32e-25 GO:0005829 cytosol
1.13 1.62e-23 GO:0043229 intracellular organelle
1.13 3.38e-23 GO:0043226 organelle
1.39 2.20e-22 GO:0044428 nuclear part
1.20 7.65e-21 GO:0044444 cytoplasmic part
1.21 2.60e-20 GO:0044446 intracellular organelle part
1.14 4.60e-20 GO:0043231 intracellular membrane-bounded organelle
1.14 7.11e-20 GO:0043227 membrane-bounded organelle
1.20 1.00e-19 GO:0044422 organelle part
1.35 2.49e-19 GO:0031974 membrane-enclosed lumen
1.35 4.21e-19 GO:0043233 organelle lumen
1.40 4.28e-19 GO:0031981 nuclear lumen
1.34 8.16e-18 GO:0070013 intracellular organelle lumen
1.28 3.49e-15 GO:0043228 non-membrane-bounded organelle
1.28 3.49e-15 GO:0043232 intracellular non-membrane-bounded organelle
1.18 4.72e-15 GO:0005634 nucleus
1.24 2.07e-14 GO:0032991 macromolecular complex
1.36 2.35e-10 GO:0005654 nucleoplasm
1.57 2.13e-09 GO:0030529 ribonucleoprotein complex
1.21 7.22e-09 GO:0043234 protein complex
1.51 3.05e-07 GO:0005730 nucleolus
2.17 2.74e-06 GO:0001726 ruffle
1.91 4.12e-06 GO:0000793 condensed chromosome
1.76 2.20e-05 GO:0031252 cell leading edge
1.42 2.86e-05 GO:0005694 chromosome
1.24 4.72e-05 GO:0012505 endomembrane system
1.79 2.06e-04 GO:0000775 chromosome, centromeric region
1.67 6.08e-04 GO:0005819 spindle
2.51 1.17e-03 GO:0032587 ruffle membrane
1.75 1.59e-03 GO:0005681 spliceosomal complex
1.92 1.94e-03 GO:0000776 kinetochore
1.99 2.07e-03 GO:0000779 condensed chromosome, centromeric region
1.20 3.17e-03 GO:0005856 cytoskeleton
1.38 4.43e-03 GO:0044427 chromosomal part
2.02 6.41e-03 GO:0030117 membrane coat
2.02 6.41e-03 GO:0048475 coated membrane
1.03 7.25e-03 GO:0044464 cell part
1.03 7.67e-03 GO:0005623 cell
1.96 7.72e-03 GO:0000777 condensed chromosome kinetochore
1.51 8.00e-03 GO:0005635 nuclear envelope
4.03 1.01e-02 GO:0030127 COPII vesicle coat
1.85 1.87e-02 GO:0046930 pore complex
1.93 2.08e-02 GO:0005643 nuclear pore
1.55 2.23e-02 GO:0005840 ribosome
1.98 3.31e-02 GO:0030496 midbody
1.56 3.54e-02 GO:0070161 anchoring junction
1.39 3.64e-02 GO:0005815 microtubule organizing center

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 1.28e-36 GO:0005515 protein binding
1.08 2.73e-13 GO:0005488 binding
1.50 7.41e-12 GO:0003723 RNA binding
2.24 4.19e-06 GO:0008135 translation factor activity, nucleic acid binding
1.19 8.85e-05 GO:0000166 nucleotide binding
2.35 9.94e-04 GO:0003743 translation initiation factor activity
1.38 1.24e-03 GO:0008092 cytoskeletal protein binding
1.17 1.02e-02 GO:0017076 purine nucleotide binding
1.17 1.11e-02 GO:0032553 ribonucleotide binding
1.17 1.11e-02 GO:0032555 purine ribonucleotide binding
1.18 1.19e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.43 2.31e-02 GO:0003779 actin binding
1.17 3.16e-02 GO:0016740 transferase activity