Motif ID: ELF1,2,4.p2

Z-value: 1.528


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF4chrX_-_1292444220.791.7e-07Click!
ELF2chr4_-_140005464-0.301.1e-01Click!
ELF1chr13_-_41593491-0.077.3e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_137801166 3.122 EGR1
early growth response 1
chr17_+_2699731 3.118 NM_001100398
NM_015085
 RAP1GAP2

RAP1 GTPase activating protein 2

chr6_+_80714321 3.076 NM_001166691
NM_003318
 TTK

TTK protein kinase

chrX_-_153775427 3.060 G6PD
glucose-6-phosphate dehydrogenase
chr6_+_80714389 2.766 TTK
TTK protein kinase
chr13_-_60738078 2.725 NM_001042517
 DIAPH3
diaphanous homolog 3 (Drosophila)
chr8_+_22462267 2.636 KIAA1967
KIAA1967
chr11_-_46722139 2.482 ARHGAP1
Rho GTPase activating protein 1
chr1_+_169764174 2.418 C1orf112
chromosome 1 open reading frame 112
chr18_+_56338783 2.302 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr15_+_38544119 2.292 SPRED1
sprouty-related, EVH1 domain containing 1
chr5_+_137801178 2.225 NM_001964
 EGR1
early growth response 1
chr7_+_40174480 2.181 NM_001193311
NM_001193312
NM_001193313
NM_024728
 C7orf10



chromosome 7 open reading frame 10



chr12_-_123214882 2.151 NM_032554
 HCAR1
hydroxycarboxylic acid receptor 1
chr13_-_60737899 2.131 DIAPH3
diaphanous homolog 3 (Drosophila)
chr7_-_97601654 2.114


chr5_+_892950 2.105 NM_001166260
NM_004237
 TRIP13

thyroid hormone receptor interactor 13

chr8_+_26371461 2.104 NM_001197293
 DPYSL2
dihydropyrimidinase-like 2
chr19_-_51845377 2.066 NM_001163922
 VSIG10L
V-set and immunoglobulin domain containing 10 like
chr11_-_46722160 2.045 ARHGAP1
Rho GTPase activating protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 138 entries
enrichment   p-value GO term description
2.22 4.69e-05 GO:0000216 M/G1 transition of mitotic cell cycle
2.11 6.01e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.08 1.28e-02 GO:0006405 RNA export from nucleus
2.02 4.94e-05 GO:0051320 S phase
2.02 6.70e-05 GO:0000084 S phase of mitotic cell cycle
2.02 3.53e-03 GO:0051168 nuclear export
2.02 4.79e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.02 1.20e-02 GO:0000209 protein polyubiquitination
2.02 2.22e-02 GO:0051352 negative regulation of ligase activity
2.02 2.22e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.99 7.21e-03 GO:0022618 ribonucleoprotein complex assembly
1.99 1.33e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.97 5.81e-03 GO:0071826 ribonucleoprotein complex subunit organization
1.93 5.00e-03 GO:0051340 regulation of ligase activity
1.93 9.18e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
1.92 2.15e-03 GO:0007059 chromosome segregation
1.92 1.69e-02 GO:0018196 peptidyl-asparagine modification
1.92 1.69e-02 GO:0018279 protein N-linked glycosylation via asparagine
1.92 3.10e-02 GO:0051351 positive regulation of ligase activity
1.89 7.30e-05 GO:0000082 G1/S transition of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 50 entries
enrichment   p-value GO term description
4.03 1.01e-02 GO:0030127 COPII vesicle coat
2.51 1.17e-03 GO:0032587 ruffle membrane
2.17 2.74e-06 GO:0001726 ruffle
2.02 6.41e-03 GO:0030117 membrane coat
2.02 6.41e-03 GO:0048475 coated membrane
1.99 2.07e-03 GO:0000779 condensed chromosome, centromeric region
1.98 3.31e-02 GO:0030496 midbody
1.96 7.72e-03 GO:0000777 condensed chromosome kinetochore
1.93 2.08e-02 GO:0005643 nuclear pore
1.92 1.94e-03 GO:0000776 kinetochore
1.91 4.12e-06 GO:0000793 condensed chromosome
1.85 1.87e-02 GO:0046930 pore complex
1.79 2.06e-04 GO:0000775 chromosome, centromeric region
1.76 2.20e-05 GO:0031252 cell leading edge
1.75 1.59e-03 GO:0005681 spliceosomal complex
1.67 6.08e-04 GO:0005819 spindle
1.57 2.13e-09 GO:0030529 ribonucleoprotein complex
1.56 3.54e-02 GO:0070161 anchoring junction
1.55 2.23e-02 GO:0005840 ribosome
1.51 3.05e-07 GO:0005730 nucleolus

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.35 9.94e-04 GO:0003743 translation initiation factor activity
2.24 4.19e-06 GO:0008135 translation factor activity, nucleic acid binding
1.50 7.41e-12 GO:0003723 RNA binding
1.43 2.31e-02 GO:0003779 actin binding
1.38 1.24e-03 GO:0008092 cytoskeletal protein binding
1.22 1.28e-36 GO:0005515 protein binding
1.19 8.85e-05 GO:0000166 nucleotide binding
1.18 1.19e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.17 1.02e-02 GO:0017076 purine nucleotide binding
1.17 1.11e-02 GO:0032553 ribonucleotide binding
1.17 1.11e-02 GO:0032555 purine ribonucleotide binding
1.17 3.16e-02 GO:0016740 transferase activity
1.08 2.73e-13 GO:0005488 binding