Motif ID: EOMES.p2

Z-value: 0.842


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EOMESchr3_-_27763784-0.029.0e-01Click!


Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_35938736 3.404 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr5_+_94727047 3.342 NM_152548
FAM81B
family with sequence similarity 81, member B
chr1_+_38022514 2.770 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr11_+_73358593 2.392 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr19_-_7990974 2.145 NM_206833
CTXN1
cortexin 1
chr8_-_146202727 1.867 ZNF252
zinc finger protein 252
chr10_+_114135965 1.836 ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_+_131438451 1.735 NM_198827
GPR133
G protein-coupled receptor 133
chr5_+_156820161 1.559 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_161337663 1.541 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr14_-_106774311 1.396 IGHA1
immunoglobulin heavy constant alpha 1
chr1_-_46089638 1.369 NM_001114938
NM_001190182
CCDC17

coiled-coil domain containing 17

chr12_+_69742130 1.319 NM_000239
LYZ
lysozyme
chr15_+_60296506 1.172 FOXB1
forkhead box B1
chr15_+_60296420 1.155 NM_012182
FOXB1
forkhead box B1
chr10_+_114135937 1.128 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr9_-_112970412 1.119 NM_001012993
C9orf152
chromosome 9 open reading frame 152
chr12_+_69742140 1.078 LYZ
lysozyme
chr6_+_39760148 1.044 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr10_+_114136014 1.035 ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_16077740 1.030 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr19_+_55888203 1.022 NM_139172
TMEM190
transmembrane protein 190
chr16_-_52581713 1.009 NM_001146188
TOX3
TOX high mobility group box family member 3
chr9_-_117150217 1.004 AKNA
AT-hook transcription factor
chr10_+_118305427 0.976 NM_000936
PNLIP
pancreatic lipase
chr19_-_44831907 0.934 ZFP112
zinc finger protein 112 homolog (mouse)
chr9_-_75568232 0.899 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr10_+_114154522 0.897 ACSL5
acyl-CoA synthetase long-chain family member 5
chr12_-_71551564 0.890 TSPAN8
tetraspanin 8
chr12_-_71551778 0.861 NM_004616
TSPAN8
tetraspanin 8
chr13_-_39564857 0.815 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr5_+_113698304 0.808 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_+_219246751 0.806 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr17_+_35849950 0.805 NM_007026
DUSP14
dual specificity phosphatase 14
chr3_-_122102057 0.784 NM_001017928
CCDC58
coiled-coil domain containing 58
chr17_+_35849997 0.779 DUSP14
dual specificity phosphatase 14
chr12_+_50451486 0.774 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr3_-_45837912 0.769 SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr4_-_177116713 0.765 NM_144644
SPATA4
spermatogenesis associated 4
chr16_+_71560022 0.760 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr15_-_40857229 0.749 NM_001080791
NM_001080792
NM_052849
C15orf57


chromosome 15 open reading frame 57


chr17_-_56406120 0.735 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr11_-_33913835 0.734 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_114135013 0.721 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr7_-_16505292 0.693 NM_015464
SOSTDC1
sclerostin domain containing 1
chr12_-_7848324 0.689 NM_020634
GDF3
growth differentiation factor 3
chr19_-_14992166 0.682 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr1_+_17846818 0.678 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_-_26633110 0.676 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr1_+_212782103 0.665 ATF3
activating transcription factor 3
chr10_-_123356158 0.658 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr3_-_66551341 0.658 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr19_+_50713823 0.655 MYH14
myosin, heavy chain 14, non-muscle
chr11_+_6260321 0.647 NM_001037329
CNGA4
cyclic nucleotide gated channel alpha 4
chr1_-_46598250 0.629 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr19_-_14260728 0.627 LPHN1
latrophilin 1
chr6_-_32497925 0.626 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr3_-_42843217 0.620


chr9_-_75567915 0.617 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_+_96211643 0.616 NM_001130140
NM_022350
ERAP2

endoplasmic reticulum aminopeptidase 2

chr1_+_212781969 0.598 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr11_-_9225780 0.589 DENND5A
DENN/MADD domain containing 5A
chr11_-_5271035 0.569 NM_000559
HBG1
hemoglobin, gamma A
chr1_-_85930610 0.543 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_+_47264669 0.532 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr9_-_117267710 0.524 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr11_+_45907046 0.523 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr4_-_69111333 0.518 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr20_+_44098392 0.516 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr17_+_25958257 0.515 LGALS9
lectin, galactoside-binding, soluble, 9
chr11_+_45907198 0.514 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr2_-_61697899 0.514 USP34
ubiquitin specific peptidase 34
chr3_-_100712248 0.506 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr17_+_25958245 0.500 LGALS9
lectin, galactoside-binding, soluble, 9
chr5_+_113698015 0.500 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_-_61697846 0.498 NM_014709
USP34
ubiquitin specific peptidase 34
chr13_+_99058147 0.492


chr3_-_12941547 0.487 IQSEC1
IQ motif and Sec7 domain 1
chr3_+_47029453 0.486 NBEAL2
neurobeachin-like 2
chr17_+_26800657 0.483 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr11_+_73661363 0.483 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr5_+_96212167 0.483 ERAP2
endoplasmic reticulum aminopeptidase 2
chr7_-_99766238 0.477 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr19_+_36236460 0.472 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chrX_+_37865834 0.461 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr4_-_170924911 0.459 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr20_-_62199106 0.449 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr7_-_99573637 0.441 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr6_+_135502445 0.433 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr1_+_147013181 0.431 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr12_+_56473944 0.430 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr2_+_102770401 0.429 NM_000877
IL1R1
interleukin 1 receptor, type I
chr4_+_160188997 0.426 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_82395401 0.423 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chrM_-_9203 0.421


chr7_-_99766191 0.416 GAL3ST4
galactose-3-O-sulfotransferase 4
chr3_-_52444016 0.415 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr5_-_138719018 0.414 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr20_+_138121 0.411 NM_139074
DEFB127
defensin, beta 127
chr1_+_26737306 0.399 LIN28A
lin-28 homolog A (C. elegans)
chr1_+_61547388 0.399 NM_001145512
NFIA
nuclear factor I/A
chr19_-_6433772 0.398 NM_173637
SLC25A41
solute carrier family 25, member 41
chr16_-_18937722 0.397 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr1_+_174769034 0.391 NM_001243765
RABGAP1L
RAB GTPase activating protein 1-like
chr14_-_76447445 0.390 TGFB3
transforming growth factor, beta 3
chr5_-_177099174 0.387 LOC202181
chromosome 5 open reading frame 25 pseudogene
chr12_+_74933559 0.383


chrX_+_16804531 0.380 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr5_-_44388666 0.380 NM_004465
FGF10
fibroblast growth factor 10
chr9_-_4152182 0.379 NM_152629
GLIS3
GLIS family zinc finger 3
chr21_+_25801042 0.378 FLJ42200
FLJ42200 protein
chr8_+_75896707 0.368 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chrX_+_53449804 0.365 NM_144968
NM_001031745
RIBC1

RIB43A domain with coiled-coils 1

chr1_-_202858225 0.364 NM_002871
RABIF
RAB interacting factor
chr11_-_34535302 0.363 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr6_+_135502477 0.359 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr17_+_1619816 0.358 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr21_-_36421630 0.357 RUNX1
runt-related transcription factor 1
chr5_-_138718941 0.357 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr7_+_138482696 0.355 NM_001085429
TMEM213
transmembrane protein 213
chr9_-_14722669 0.350 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr11_-_114466397 0.340 FAM55D
family with sequence similarity 55, member D
chr12_+_124773709 0.335 NM_181709
FAM101A
family with sequence similarity 101, member A
chrX_-_19688991 0.334 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr6_+_135502521 0.333 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chrX_-_10645726 0.333 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr2_-_26101173 0.332 ASXL2
additional sex combs like 2 (Drosophila)
chr16_-_75590107 0.332 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231


chr16_-_20364029 0.327 NM_001008389
NM_003361
UMOD

uromodulin

chr5_+_175665337 0.326 NM_198567
C5orf25
chromosome 5 open reading frame 25
chr1_+_16062808 0.324 NM_207348
SLC25A34
solute carrier family 25, member 34
chr2_-_26101091 0.324


chr17_-_39216343 0.318 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr11_-_5275904 0.317 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr10_+_7745229 0.315 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_+_113623364 0.313 NM_032848
C12orf52
chromosome 12 open reading frame 52
chr3_-_46505077 0.313 NM_001199149
LTF
lactotransferrin
chr3_-_146213721 0.308 NM_001199979
PLSCR2
phospholipid scramblase 2
chr5_-_124080773 0.308 NM_020747
ZNF608
zinc finger protein 608
chr8_+_104831415 0.307 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr12_+_56862300 0.306 NM_207344
SPRYD4
SPRY domain containing 4
chr14_+_51026742 0.306 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr21_-_36421578 0.304 RUNX1
runt-related transcription factor 1
chr1_+_89829435 0.299 NM_198460
GBP6
guanylate binding protein family, member 6
chr15_+_63889551 0.298 NM_203373
FBXL22
F-box and leucine-rich repeat protein 22
chr18_+_54424444 0.296 WDR7
WD repeat domain 7
chrX_+_44732402 0.295 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr11_-_44972227 0.292 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr6_+_30951484 0.284 NM_001010909
MUC21
mucin 21, cell surface associated
chr3_+_108021331 0.283 NM_007072
HHLA2
HERV-H LTR-associating 2
chr6_+_30295007 0.283 NM_172016
TRIM39
tripartite motif containing 39
chr1_+_27101217 0.283 ARID1A
AT rich interactive domain 1A (SWI-like)
chr6_-_13487772 0.280 NM_001242629
NM_018988
GFOD1

glucose-fructose oxidoreductase domain containing 1

chr11_+_36397534 0.280 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr18_+_18822168 0.277 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr6_-_29012951 0.277 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr1_-_76076762 0.272 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr6_+_30294620 0.270 NM_021253
TRIM39
tripartite motif containing 39
chr1_+_26737232 0.269 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr2_-_237172987 0.267 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr19_-_6333561 0.267 NM_133492
ACER1
alkaline ceramidase 1
chr5_+_61714710 0.264 NM_001134779
IPO11
importin 11
chr2_+_113993082 0.263 LOC654433
uncharacterized LOC654433
chr3_-_52443893 0.262 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr21_-_36421586 0.258 NM_001754
RUNX1
runt-related transcription factor 1
chr16_-_67965754 0.255 NM_001907
CTRL
chymotrypsin-like
chr15_-_90349819 0.254 ANPEP
alanyl (membrane) aminopeptidase
chr10_-_75335415 0.252 NM_152586
USP54
ubiquitin specific peptidase 54
chr17_-_20370819 0.252 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chrX_-_48693934 0.249 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr2_-_128100673 0.248 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr21_-_36421461 0.247 RUNX1
runt-related transcription factor 1
chr2_-_234474197 0.245 NM_018218
USP40
ubiquitin specific peptidase 40
chr16_-_81110803 0.244 NM_001100873
NM_152337
C16orf46

chromosome 16 open reading frame 46

chr11_-_132812870 0.243 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr9_-_79520878 0.238 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr15_+_41062158 0.238 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr11_-_62521533 0.237 NM_024784
ZBTB3
zinc finger and BTB domain containing 3
chrX_-_15872905 0.237


chr3_-_114478117 0.237 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_-_34043234 0.236 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr14_+_95078713 0.236 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr7_+_100027404 0.234 MEPCE
methylphosphate capping enzyme
chr11_-_65363466 0.234 NM_005714
NM_033347
NM_033348
NM_033455
KCNK7



potassium channel, subfamily K, member 7



chr21_-_46340776 0.234 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr15_+_78556485 0.233 NM_018602
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr6_+_167738573 0.232 NM_031949
TTLL2
tubulin tyrosine ligase-like family, member 2
chrX_+_57313109 0.231 NM_174912
FAAH2
fatty acid amide hydrolase 2
chr17_+_25958217 0.230 LGALS9
lectin, galactoside-binding, soluble, 9
chr16_+_2817654 0.230 SRRM2
serine/arginine repetitive matrix 2
chrX_-_15872921 0.230 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr15_+_73344824 0.229 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr17_+_58755158 0.228 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr9_-_5968367 0.225


chr1_+_27114409 0.224 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr2_-_200322699 0.224 NM_001172509
SATB2
SATB homeobox 2
chr12_-_52761254 0.223 NM_002283
KRT85
keratin 85
chrX_-_32430370 0.223 NM_004011
NM_004012
DMD

dystrophin

chr11_-_61348290 0.219 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr4_-_54457723 0.218 NM_001126328
LNX1
ligand of numb-protein X 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.48 2.16e-02 GO:0005887 integral to plasma membrane
1.45 4.43e-02 GO:0031226 intrinsic to plasma membrane

Nothing significant found in function category.