Motif ID: EP300.p2

Z-value: 1.215


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_41488607-0.604.2e-04Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_28681429 4.096 DSC2
desmocollin 2
chr18_-_28681885 3.354 NM_004949
NM_024422
 DSC2

desmocollin 2

chr12_-_25101993 2.763 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_54813002 2.581 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_+_33750463 2.155 NM_001197097
NM_007343
NM_001197098
 PRSS3


protease, serine, 3


chr19_-_11689591 2.041 NM_001111034
 ACP5
acid phosphatase 5, tartrate resistant
chr12_-_54812936 1.998 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr22_-_37640187 1.895 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_+_110371887 1.887 NM_023016
 ANKRD57
ankyrin repeat domain 57
chr1_+_20915440 1.871 NM_001785
 CDA
cytidine deaminase
chr1_-_109825683 1.823 PSRC1
proline/serine-rich coiled-coil 1
chr7_-_752083 1.817 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr10_-_116164514 1.790 NM_001001936
NM_032550
 AFAP1L2

actin filament associated protein 1-like 2

chr12_+_70759974 1.752 NM_014505
 KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr22_-_37640287 1.750 NM_002872
 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_57634474 1.733 NM_020142
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chrX_+_135229536 1.665 NM_001159702
NM_001159703
NM_001449
 FHL1


four and a half LIM domains 1


chr7_+_48128939 1.621 UPP1
uridine phosphorylase 1
chr19_-_11689765 1.576 NM_001111035
NM_001111036
 ACP5

acid phosphatase 5, tartrate resistant

chr10_-_3827205 1.568 KLF6
Kruppel-like factor 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
2.05 3.76e-03 GO:0007265 Ras protein signal transduction
1.68 1.88e-02 GO:0030168 platelet activation
1.62 4.41e-07 GO:0050878 regulation of body fluid levels
1.61 1.16e-05 GO:0007599 hemostasis
1.60 2.70e-05 GO:0007596 blood coagulation
1.60 2.70e-05 GO:0050817 coagulation
1.58 4.10e-06 GO:0042060 wound healing
1.43 4.67e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.40 8.32e-04 GO:0040011 locomotion
1.36 3.43e-03 GO:0009611 response to wounding
1.32 1.92e-02 GO:0032879 regulation of localization
1.27 2.01e-02 GO:0035556 intracellular signal transduction
1.25 2.45e-02 GO:0009653 anatomical structure morphogenesis
1.25 3.76e-02 GO:0007399 nervous system development
1.24 3.00e-09 GO:0023052 signaling
1.24 3.19e-02 GO:0023051 regulation of signaling
1.23 1.48e-03 GO:0065008 regulation of biological quality
1.22 3.33e-06 GO:0007165 signal transduction
1.20 1.25e-03 GO:0048731 system development
1.18 2.72e-03 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.83 1.37e-02 GO:0005938 cell cortex
1.70 1.25e-02 GO:0031252 cell leading edge
1.68 4.06e-02 GO:0070161 anchoring junction
1.66 3.01e-04 GO:0015629 actin cytoskeleton
1.47 1.28e-04 GO:0030054 cell junction
1.46 1.47e-02 GO:0045202 synapse
1.29 1.95e-07 GO:0005829 cytosol
1.21 1.73e-03 GO:0044459 plasma membrane part
1.16 2.01e-02 GO:0043228 non-membrane-bounded organelle
1.16 2.01e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.13 1.22e-02 GO:0071944 cell periphery
1.12 1.94e-08 GO:0005737 cytoplasm
1.12 3.93e-04 GO:0044444 cytoplasmic part
1.05 7.69e-03 GO:0044424 intracellular part
1.05 1.88e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.56 5.56e-03 GO:0003779 actin binding
1.50 1.60e-04 GO:0008092 cytoskeletal protein binding
1.20 2.74e-20 GO:0005515 protein binding
1.08 1.44e-08 GO:0005488 binding