Motif ID: ESRRA.p2

Z-value: 1.946


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESRRAchr11_+_640730400.514.0e-03Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_118187381 6.358 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr20_+_58179601 6.016 NM_080672
 PHACTR3
phosphatase and actin regulator 3
chr1_+_152881022 4.272 NM_005547
 IVL
involucrin
chr5_+_218447 3.632 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr5_+_218355 3.268 NM_004168
 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr2_-_31030271 3.192 NM_144575
 CAPN13
calpain 13
chr10_+_81107242 3.062 PPIF
peptidylprolyl isomerase F
chr3_+_133465250 2.951 TF
transferrin
chr3_+_133465098 2.883 TF
transferrin
chr3_+_133465204 2.803 TF
transferrin
chr3_+_133464883 2.685 NM_001063
 TF
transferrin
chr1_-_144994908 2.675 PDE4DIP
phosphodiesterase 4D interacting protein
chrX_-_7895764 2.626 NM_001142389
NM_001172672
 PNPLA4

patatin-like phospholipase domain containing 4

chr5_+_218441 2.595 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr12_+_102091399 2.432 NM_020244
 CHPT1
choline phosphotransferase 1
chr12_-_120554558 2.358 RAB35
RAB35, member RAS oncogene family
chr10_+_81107259 2.330 PPIF
peptidylprolyl isomerase F
chr11_+_66624501 2.118 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr20_-_46415277 2.070 NM_001161841
NM_198596
 SULF2

sulfatase 2

chr13_-_114566951 2.045 GAS6
growth arrest-specific 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
17.78 2.02e-02 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
7.00 2.12e-05 GO:0009060 aerobic respiration
6.87 1.63e-07 GO:0042773 ATP synthesis coupled electron transport
6.87 1.63e-07 GO:0042775 mitochondrial ATP synthesis coupled electron transport
6.57 2.88e-16 GO:0022904 respiratory electron transport chain
6.53 1.22e-07 GO:0006119 oxidative phosphorylation
5.93 6.79e-04 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
5.83 2.85e-17 GO:0045333 cellular respiration
4.72 2.74e-11 GO:0022900 electron transport chain
3.93 2.00e-03 GO:0006839 mitochondrial transport
3.47 1.42e-11 GO:0015980 energy derivation by oxidation of organic compounds
3.23 6.22e-04 GO:0007005 mitochondrion organization
2.83 1.07e-09 GO:0006091 generation of precursor metabolites and energy
1.98 5.61e-07 GO:0055114 oxidation-reduction process
1.44 1.01e-05 GO:0006810 transport
1.42 3.56e-05 GO:0051234 establishment of localization
1.34 7.22e-04 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
6.73 1.77e-12 GO:0070469 respiratory chain
6.70 2.47e-11 GO:0005746 mitochondrial respiratory chain
5.93 3.96e-05 GO:0005747 mitochondrial respiratory chain complex I
5.93 3.96e-05 GO:0030964 NADH dehydrogenase complex
5.93 3.96e-05 GO:0045271 respiratory chain complex I
5.78 2.23e-17 GO:0044455 mitochondrial membrane part
4.71 2.91e-02 GO:0042645 mitochondrial nucleoid
4.57 3.73e-02 GO:0009295 nucleoid
4.42 9.79e-26 GO:0005743 mitochondrial inner membrane
4.16 1.19e-24 GO:0019866 organelle inner membrane
3.63 1.13e-23 GO:0031966 mitochondrial membrane
3.52 6.33e-23 GO:0005740 mitochondrial envelope
3.16 4.38e-26 GO:0044429 mitochondrial part
2.85 7.26e-07 GO:0005759 mitochondrial matrix
2.59 4.56e-16 GO:0031975 envelope
2.58 1.26e-15 GO:0031967 organelle envelope
2.42 9.82e-26 GO:0005739 mitochondrion
1.55 5.11e-07 GO:0031090 organelle membrane
1.35 7.06e-12 GO:0044444 cytoplasmic part
1.26 3.55e-12 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
5.93 1.80e-02 GO:0004129 cytochrome-c oxidase activity
5.93 1.80e-02 GO:0015002 heme-copper terminal oxidase activity
5.93 1.80e-02 GO:0016675 oxidoreductase activity, acting on a heme group of donors
5.93 1.80e-02 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
5.77 2.65e-04 GO:0003954 NADH dehydrogenase activity
5.77 2.65e-04 GO:0008137 NADH dehydrogenase (ubiquinone) activity
5.77 2.65e-04 GO:0050136 NADH dehydrogenase (quinone) activity
5.38 2.22e-04 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
4.45 3.09e-02 GO:0003823 antigen binding
4.22 1.63e-06 GO:0015078 hydrogen ion transmembrane transporter activity
2.99 9.37e-03 GO:0051082 unfolded protein binding
2.74 6.61e-04 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.52 5.25e-04 GO:0022890 inorganic cation transmembrane transporter activity
2.51 1.64e-02 GO:0009055 electron carrier activity
1.94 2.13e-05 GO:0016491 oxidoreductase activity
1.19 4.72e-02 GO:0003824 catalytic activity