Motif ID: ETS1,2.p2

Z-value: 1.206


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS2chr21_+_401778470.504.8e-03Click!
ETS1chr11_-_1284574520.441.5e-02Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_154946859 3.828 NM_001130041
NM_001202859
NM_003029
 SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr13_-_20805371 3.289 NM_006783
 GJB6
gap junction protein, beta 6, 30kDa
chr1_-_154946830 3.212 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr12_-_57634474 3.014 NM_020142
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr5_-_151066445 2.807 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_88717319 2.772 NM_024756
 MMRN2
multimerin 2
chr1_-_154946801 2.762 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr4_+_2813966 2.684 SH3BP2
SH3-domain binding protein 2
chr1_-_153044083 2.615 NM_001017418
 SPRR2B
small proline-rich protein 2B
chr17_-_8113862 2.347 NM_004217
 AURKB
aurora kinase B
chr19_+_35646006 2.307 FXYD5
FXYD domain containing ion transport regulator 5
chr2_+_102953716 2.302 NM_003856
 IL1RL1
interleukin 1 receptor-like 1
chr19_+_35645640 2.301 NM_144779
NM_001164605
 FXYD5

FXYD domain containing ion transport regulator 5

chr19_+_35645614 2.270 NM_014164
 FXYD5
FXYD domain containing ion transport regulator 5
chr5_-_151066492 2.172 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr11_+_2920910 2.151 NM_183233
 SLC22A18
solute carrier family 22, member 18
chr13_-_60738078 2.117 NM_001042517
 DIAPH3
diaphanous homolog 3 (Drosophila)
chr17_+_9729380 2.097 NM_004246
 GLP2R
glucagon-like peptide 2 receptor
chr12_+_8975149 1.991 NM_144670
 A2ML1
alpha-2-macroglobulin-like 1
chr1_+_16083132 1.988 FBLIM1
filamin binding LIM protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
2.27 1.85e-02 GO:0007015 actin filament organization
2.11 1.58e-02 GO:0006414 translational elongation
1.96 5.64e-03 GO:0034330 cell junction organization
1.80 5.73e-04 GO:0030036 actin cytoskeleton organization
1.79 1.97e-02 GO:0022411 cellular component disassembly
1.79 1.97e-02 GO:0071845 cellular component disassembly at cellular level
1.70 9.08e-04 GO:0006412 translation
1.70 2.50e-02 GO:0030168 platelet activation
1.68 4.07e-03 GO:0030029 actin filament-based process
1.54 1.03e-04 GO:0071822 protein complex subunit organization
1.52 2.55e-04 GO:0042060 wound healing
1.52 4.40e-03 GO:0007010 cytoskeleton organization
1.51 5.59e-03 GO:0007596 blood coagulation
1.51 5.59e-03 GO:0050817 coagulation
1.50 7.97e-03 GO:0007599 hemostasis
1.49 1.13e-02 GO:0001775 cell activation
1.47 2.82e-02 GO:0034621 cellular macromolecular complex subunit organization
1.46 4.24e-02 GO:0070271 protein complex biogenesis
1.45 1.80e-02 GO:0050878 regulation of body fluid levels
1.41 1.08e-03 GO:0043933 macromolecular complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
2.79 7.59e-03 GO:0032587 ruffle membrane
2.33 6.41e-03 GO:0031256 leading edge membrane
2.32 3.65e-05 GO:0005925 focal adhesion
2.26 5.67e-05 GO:0005924 cell-substrate adherens junction
2.23 6.26e-05 GO:0030055 cell-substrate junction
2.19 3.33e-03 GO:0030027 lamellipodium
2.00 1.30e-04 GO:0005912 adherens junction
2.00 3.59e-02 GO:0001726 ruffle
2.00 3.59e-02 GO:0042470 melanosome
2.00 3.59e-02 GO:0048770 pigment granule
1.95 1.32e-04 GO:0070161 anchoring junction
1.89 1.99e-04 GO:0031252 cell leading edge
1.66 7.90e-03 GO:0016323 basolateral plasma membrane
1.63 1.85e-03 GO:0015629 actin cytoskeleton
1.42 1.40e-02 GO:0030529 ribonucleoprotein complex
1.34 5.62e-10 GO:0005829 cytosol
1.18 3.04e-03 GO:0043228 non-membrane-bounded organelle
1.18 3.04e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.16 5.76e-08 GO:0044444 cytoplasmic part
1.15 1.19e-13 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.40 1.07e-03 GO:0042802 identical protein binding
1.20 1.19e-18 GO:0005515 protein binding
1.07 4.08e-06 GO:0005488 binding