Motif ID: EVI1.p2

Z-value: 0.975


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
EVI1 2122 ecotropic viral integration site 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MECOMchr3_-_168864325-0.183.5e-01Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_135782246 2.740 NM_001018046
NM_025052
 YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr17_+_53344966 2.109 HLF
hepatic leukemia factor
chr12_-_8219001 1.945 C3AR1
complement component 3a receptor 1
chr12_-_8218930 1.646 NM_004054
 C3AR1
complement component 3a receptor 1
chr11_-_64727608 1.553 NM_001037225
 C11orf85
chromosome 11 open reading frame 85
chr6_-_22297729 1.510 NM_000948
 PRL
prolactin
chr5_-_41213513 1.435 NM_000065
 C6
complement component 6
chrX_+_15525430 1.418 NM_001721
 BMX
BMX non-receptor tyrosine kinase
chrX_-_101694848 1.406 NM_022053
NM_001099686
 NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr14_-_76447323 1.406 TGFB3
transforming growth factor, beta 3
chrX_+_101502093 1.400 NM_022053
NM_001099686
 NXF2
NXF2B
nuclear RNA export factor 2
nuclear RNA export factor 2B
chr5_+_121465214 1.247 NM_207317
 ZNF474
zinc finger protein 474
chr19_+_6135650 1.227 NM_030924
 ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr5_-_137475076 1.188 NM_003551
 NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr1_+_179575361 1.170 NM_001199092
 TDRD5
tudor domain containing 5
chr3_-_145968819 1.166 PLSCR4
phospholipid scramblase 4
chr3_+_97158453 1.160 NM_173655
 EPHA6
EPH receptor A6
chr7_-_16921596 1.113 NM_176813
 AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr19_-_41388656 1.096 NM_000764
NM_030589
 CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr10_+_7745325 1.085 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
3.06 1.43e-02 GO:0051606 detection of stimulus
2.96 9.41e-05 GO:0050867 positive regulation of cell activation
2.92 2.23e-04 GO:0002696 positive regulation of leukocyte activation
2.87 5.53e-03 GO:0042445 hormone metabolic process
2.78 2.90e-05 GO:0002694 regulation of leukocyte activation
2.78 2.50e-03 GO:0050863 regulation of T cell activation
2.74 2.59e-05 GO:0050865 regulation of cell activation
2.73 2.71e-04 GO:0051249 regulation of lymphocyte activation
2.71 6.44e-03 GO:0051251 positive regulation of lymphocyte activation
2.65 2.79e-03 GO:0010817 regulation of hormone levels
2.45 5.84e-04 GO:0006954 inflammatory response
2.27 6.86e-03 GO:0050778 positive regulation of immune response
2.16 2.49e-04 GO:0050776 regulation of immune response
2.01 5.87e-03 GO:0002684 positive regulation of immune system process
1.88 5.24e-05 GO:0006952 defense response
1.87 6.54e-04 GO:0002682 regulation of immune system process
1.72 1.58e-03 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.88 2.97e-02 GO:0009986 cell surface
1.70 2.55e-06 GO:0005887 integral to plasma membrane
1.68 3.87e-06 GO:0031226 intrinsic to plasma membrane
1.63 8.94e-03 GO:0005615 extracellular space
1.52 6.39e-07 GO:0044459 plasma membrane part
1.47 3.98e-05 GO:0005576 extracellular region
1.33 2.52e-06 GO:0005886 plasma membrane
1.32 4.96e-06 GO:0071944 cell periphery
1.22 6.99e-04 GO:0031224 intrinsic to membrane
1.22 9.66e-04 GO:0016021 integral to membrane
1.17 6.64e-03 GO:0044425 membrane part
1.15 4.61e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.39 3.14e-02 GO:0004872 receptor activity