Motif ID: EWSR1-FLI1.p2

Z-value: 0.619


Transcription factors associated with EWSR1-FLI1.p2:

fusion protein between EWSR1 and FLI1 in an oncogenic event

Gene SymbolEntrez IDGene Name
EWSR1 2130 Ewing sarcoma breakpoint region 1
FLI1 2313 Friend leukemia virus integration 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EWSR1chr22_+_296642160.301.1e-01Click!
FLI1chr11_+_128563772-0.251.8e-01Click!


Activity profile for motif EWSR1-FLI1.p2.

activity profile for motif EWSR1-FLI1.p2


Sorted Z-values histogram for motif EWSR1-FLI1.p2

Sorted Z-values for motif EWSR1-FLI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EWSR1-FLI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_37892786 1.658 NM_001163334
 SYTL5
synaptotagmin-like 5
chr3_-_42307661 0.987 NM_000729
 CCK
cholecystokinin
chr18_+_43405544 0.737 NM_213602
 SIGLEC15
sialic acid binding Ig-like lectin 15
chrX_+_585078 0.644 NM_000451
NM_006883
 SHOX

short stature homeobox

chrY_+_535078 0.636 NM_000451
NM_006883
 SHOX

short stature homeobox

chr9_-_124990706 0.616 NM_001242333
 LHX6
LIM homeobox 6
chr6_-_25832268 0.570 NM_005074
 SLC17A1
solute carrier family 17 (sodium phosphate), member 1
chrX_-_109561427 0.534 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr20_+_43374487 0.514 NM_022358
 KCNK15
potassium channel, subfamily K, member 15
chr6_+_116937641 0.510 NM_001010892
NM_001161664
 RSPH4A

radial spoke head 4 homolog A (Chlamydomonas)

chr14_-_54423448 0.505 NM_001202
NM_130850
 BMP4

bone morphogenetic protein 4

chr3_-_164914448 0.469 NM_014926
 SLITRK3
SLIT and NTRK-like family, member 3
chr2_-_99917638 0.467 NM_174898
 LYG1
lysozyme G-like 1
chr20_+_42187634 0.457 NM_170693
 SGK2
serum/glucocorticoid regulated kinase 2
chr8_+_133879202 0.456 NM_003235
 TG
thyroglobulin
chr7_-_99527242 0.420 NM_181538
 GJC3
gap junction protein, gamma 3, 30.2kDa
chrX_-_109561298 0.403 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_+_156887026 0.378 NM_001099287
NM_001172292
 NIPAL4

NIPA-like domain containing 4

chrX_+_1401570 0.371 NM_001161530
NM_172247
 CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

chr7_+_36429388 0.368 NM_018685
 ANLN
anillin, actin binding protein

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.91 2.04e-02 GO:0008201 heparin binding