Motif ID: FEV.p2

Z-value: 1.814


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2198502730.183.4e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_-_37640187 4.849 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640287 4.656 NM_002872
 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_124194873 4.370 FAM83A
family with sequence similarity 83, member A
chr1_-_154946830 4.105 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr7_+_100770378 4.037 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr5_-_39219578 3.834 NM_001465
NM_199335
 FYB

FYN binding protein

chr1_-_154946859 3.815 NM_001130041
NM_001202859
NM_003029
 SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr8_+_124194751 3.718 NM_032899
NM_207006
 FAM83A

family with sequence similarity 83, member A

chr2_+_233925104 3.675 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr8_+_27182995 3.574 NM_173176
 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr11_-_46722139 3.559 ARHGAP1
Rho GTPase activating protein 1
chr1_-_154946801 3.491 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr7_+_106505696 3.465 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_150480486 3.317 NM_001202858
NM_004425
NM_022664
 ECM1


extracellular matrix protein 1


chr8_+_27183047 3.284 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr14_+_65171243 3.283 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_150480584 3.199 ECM1
extracellular matrix protein 1
chr20_+_33759773 3.193 NM_006404
 PROCR
protein C receptor, endothelial
chr14_+_65171149 3.158 NM_015549
 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_116356199 3.123 NM_144489
 RGS3
regulator of G-protein signaling 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 75 entries
enrichment   p-value GO term description
2.40 3.36e-03 GO:0006944 cellular membrane fusion
2.31 9.42e-03 GO:0061025 membrane fusion
1.81 4.81e-03 GO:0006184 GTP catabolic process
1.75 9.65e-03 GO:0046039 GTP metabolic process
1.66 1.08e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.64 1.07e-02 GO:0071843 cellular component biogenesis at cellular level
1.63 1.97e-03 GO:0030036 actin cytoskeleton organization
1.54 6.26e-03 GO:0006412 translation
1.54 1.28e-02 GO:0030029 actin filament-based process
1.49 2.02e-04 GO:0007010 cytoskeleton organization
1.47 2.47e-02 GO:0051301 cell division
1.46 4.94e-04 GO:0006935 chemotaxis
1.46 4.94e-04 GO:0042330 taxis
1.46 7.14e-04 GO:0001775 cell activation
1.45 1.35e-03 GO:0007599 hemostasis
1.45 2.01e-02 GO:0007264 small GTPase mediated signal transduction
1.44 1.46e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.44 8.38e-03 GO:0016044 cellular membrane organization
1.44 1.06e-02 GO:0002684 positive regulation of immune system process
1.44 2.10e-02 GO:0016032 viral reproduction

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
2.01 4.23e-02 GO:0015934 large ribosomal subunit
1.90 1.09e-03 GO:0030055 cell-substrate junction
1.90 3.16e-03 GO:0005925 focal adhesion
1.89 2.18e-03 GO:0005924 cell-substrate adherens junction
1.87 2.59e-02 GO:0030027 lamellipodium
1.84 4.93e-02 GO:0046930 pore complex
1.64 2.53e-02 GO:0005912 adherens junction
1.61 1.11e-02 GO:0031252 cell leading edge
1.61 4.80e-02 GO:0044445 cytosolic part
1.32 1.18e-12 GO:0005829 cytosol
1.23 1.57e-06 GO:0044428 nuclear part
1.23 4.61e-05 GO:0031981 nuclear lumen
1.21 3.99e-07 GO:0043228 non-membrane-bounded organelle
1.21 3.99e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.21 2.19e-02 GO:0005654 nucleoplasm
1.20 1.18e-04 GO:0043233 organelle lumen
1.20 1.08e-02 GO:0005856 cytoskeleton
1.19 2.47e-04 GO:0031974 membrane-enclosed lumen
1.19 3.22e-04 GO:0070013 intracellular organelle lumen
1.18 3.21e-05 GO:0043234 protein complex

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.68 1.18e-05 GO:0005070 SH3/SH2 adaptor activity
2.40 8.81e-05 GO:0035591 signaling adaptor activity
1.95 1.72e-04 GO:0030674 protein binding, bridging
1.93 1.17e-04 GO:0060090 binding, bridging
1.59 9.16e-03 GO:0003924 GTPase activity
1.55 3.96e-04 GO:0003779 actin binding
1.50 5.88e-04 GO:0019001 guanyl nucleotide binding
1.50 5.88e-04 GO:0032561 guanyl ribonucleotide binding
1.49 1.00e-03 GO:0005525 GTP binding
1.39 1.88e-03 GO:0008092 cytoskeletal protein binding
1.28 1.98e-02 GO:0003723 RNA binding
1.20 6.01e-27 GO:0005515 protein binding
1.06 5.10e-06 GO:0005488 binding