Motif ID: FEV.p2

Z-value: 1.814


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2198502730.183.4e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_37640187 4.849 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640287 4.656 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_124194873 4.370 FAM83A
family with sequence similarity 83, member A
chr1_-_154946830 4.105 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr7_+_100770378 4.037 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr5_-_39219578 3.834 NM_001465
NM_199335
FYB

FYN binding protein

chr1_-_154946859 3.815 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr8_+_124194751 3.718 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr2_+_233925104 3.675 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr8_+_27182995 3.574 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr11_-_46722139 3.559 ARHGAP1
Rho GTPase activating protein 1
chr1_-_154946801 3.491 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr7_+_106505696 3.465 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_150480486 3.317 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr8_+_27183047 3.284 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr14_+_65171243 3.283 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_150480584 3.199 ECM1
extracellular matrix protein 1
chr20_+_33759773 3.193 NM_006404
PROCR
protein C receptor, endothelial
chr14_+_65171149 3.158 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr9_+_116356199 3.123 NM_144489
RGS3
regulator of G-protein signaling 3
chr21_-_38639593 3.120 DSCR3
Down syndrome critical region gene 3
chr14_-_69446038 3.100 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr4_-_103266577 3.094 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr4_+_8200918 3.034 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr2_+_233925035 2.986 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr5_-_39203061 2.886 FYB
FYN binding protein
chr14_-_55658205 2.868 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr11_-_46722160 2.856 ARHGAP1
Rho GTPase activating protein 1
chr2_+_31456879 2.854 NM_014600
EHD3
EH-domain containing 3
chr8_+_27183062 2.827 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr5_+_87564729 2.818 LOC100505894
uncharacterized LOC100505894
chr2_-_215896809 2.813 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr15_-_80263460 2.806 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr19_-_11689591 2.784 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr1_+_209859524 2.774 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr1_+_16083132 2.733 FBLIM1
filamin binding LIM protein 1
chr11_-_65667860 2.725 NM_005438
FOSL1
FOS-like antigen 1
chr10_+_102107074 2.716 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr12_+_15699277 2.652 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr1_-_160313056 2.647 COPA
coatomer protein complex, subunit alpha
chr19_+_35645640 2.583 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr19_+_35645614 2.572 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr11_-_46722115 2.546 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr7_+_106505739 2.507 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chrX_+_135230736 2.499 NM_001159700
FHL1
four and a half LIM domains 1
chr17_+_26662547 2.447 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr10_+_102107256 2.411


chr16_+_50321822 2.398 NM_001114
ADCY7
adenylate cyclase 7
chr1_-_27216767 2.373 GPN2
GPN-loop GTPase 2
chr5_+_96212167 2.342 ERAP2
endoplasmic reticulum aminopeptidase 2
chr15_-_59665053 2.342 MYO1E
myosin IE
chr13_-_20805371 2.341 NM_006783
GJB6
gap junction protein, beta 6, 30kDa
chr1_+_84609941 2.324 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_30652434 2.317 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_+_169337193 2.243 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr7_+_18548899 2.241 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr20_-_56286540 2.230 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr14_-_94442894 2.196 ASB2
ankyrin repeat and SOCS box containing 2
chr1_-_93342706 2.194 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr10_+_102106958 2.158 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_40610897 2.152 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr5_+_38845962 2.150 NM_003999
OSMR
oncostatin M receptor
chr1_-_27216585 2.137 GPN2
GPN-loop GTPase 2
chr1_-_160312959 2.129


chr1_+_110091185 2.124 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr14_-_94443065 2.123 NM_001202429
ASB2
ankyrin repeat and SOCS box containing 2
chr1_+_154300275 2.123 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr18_+_21452981 2.121 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr17_-_45933138 2.116 NM_199262
SP6
Sp6 transcription factor
chr17_+_40610940 2.107 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_+_102953716 2.079 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr8_-_49833823 2.076 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr7_+_106505876 2.072 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr13_+_49280619 2.070 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr14_-_53417636 2.068 FERMT2
fermitin family member 2
chr1_-_150780705 2.066 NM_000396
CTSK
cathepsin K
chr8_-_131455833 2.051 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr2_-_192711651 2.042 SDPR
serum deprivation response
chr11_-_1643324 2.005 NM_001012709
KRTAP5-4
keratin associated protein 5-4
chr2_-_190044330 2.003 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_-_39270708 2.003 NM_001243093
FYB
FYN binding protein
chr2_-_75788027 1.993 FAM176A
family with sequence similarity 176, member A
chr2_+_37571752 1.987 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr15_-_74500394 1.980 NM_001199041
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr9_-_33167084 1.978 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr2_-_75788079 1.975 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr12_-_123201319 1.970 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr21_+_30517897 1.967 C21orf7
chromosome 21 open reading frame 7
chr10_+_94833646 1.945 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr8_-_8175860 1.945 SGK223
homolog of rat pragma of Rnd2
chr9_+_103204187 1.912 NM_001198812
C9orf30-TMEFF1
C9orf30
C9orf30-TMEFF1 readthrough
chromosome 9 open reading frame 30
chr19_-_4723755 1.905 DPP9
dipeptidyl-peptidase 9
chr1_+_169337432 1.898 BLZF1
basic leucine zipper nuclear factor 1
chr6_-_41130864 1.893 TREM2
triggering receptor expressed on myeloid cells 2
chr1_+_152956563 1.893 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr12_-_57630867 1.874 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr10_+_102107001 1.874 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_-_37193609 1.872 NM_003162
STRN
striatin, calmodulin binding protein
chr6_-_42419782 1.868 NM_033502
TRERF1
transcriptional regulating factor 1
chr2_-_220407818 1.859 NM_001195731
CHPF
chondroitin polymerizing factor
chr12_+_105153258 1.859 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr20_-_48532036 1.854 SPATA2
spermatogenesis associated 2
chr17_+_40610905 1.840 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_-_123187842 1.831 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr17_-_43510204 1.801 ARHGAP27
Rho GTPase activating protein 27
chr9_+_116356407 1.791 RGS3
regulator of G-protein signaling 3
chr8_+_22462267 1.783 KIAA1967
KIAA1967
chr19_-_11688484 1.778 ACP5
acid phosphatase 5, tartrate resistant
chr17_-_26903854 1.764 ALDOC
aldolase C, fructose-bisphosphate
chr1_+_45205466 1.756 NM_006845
KIF2C
kinesin family member 2C
chr1_+_110091249 1.723 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr9_-_33167166 1.722 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr20_+_30326903 1.714 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr5_+_57787260 1.703 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr19_-_4723791 1.699 DPP9
dipeptidyl-peptidase 9
chr11_+_844111 1.698 TSPAN4
tetraspanin 4
chr1_+_152881022 1.695 NM_005547
IVL
involucrin
chr14_-_100842637 1.692 WARS
tryptophanyl-tRNA synthetase
chr5_-_1634040 1.669 LOC728613
programmed cell death 6 pseudogene
chr4_-_10023094 1.668 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_136633934 1.662 MCM6
minichromosome maintenance complex component 6
chr7_+_143318541 1.662 NM_173678
LOC154761
FAM115C
uncharacterized LOC154761
family with sequence similarity 115, member C
chr19_-_4723814 1.657 NM_139159
DPP9
dipeptidyl-peptidase 9
chr5_-_171615095 1.656 STK10
serine/threonine kinase 10
chrX_-_153775774 1.650 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr5_+_110074708 1.635 SLC25A46
solute carrier family 25, member 46
chr1_+_45205558 1.633 KIF2C
kinesin family member 2C
chr18_-_67872897 1.629 NM_173630
RTTN
rotatin
chr1_-_162381805 1.627 NM_053282
SH2D1B
SH2 domain containing 1B
chr15_+_63340314 1.617 NM_001018008
TPM1
tropomyosin 1 (alpha)
chr10_+_114206988 1.612 VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr20_-_23030141 1.607 NM_000361
THBD
thrombomodulin
chr8_-_42065193 1.605 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr16_+_77225094 1.604 MON1B
MON1 homolog B (yeast)
chr9_+_131185129 1.603 CERCAM
cerebral endothelial cell adhesion molecule
chr9_-_101017492 1.601 TBC1D2
TBC1 domain family, member 2
chr11_+_844062 1.599 NM_001025234
TSPAN4
tetraspanin 4
chr16_+_1583657 1.597 TMEM204
transmembrane protein 204
chr6_-_41130921 1.596 NM_018965
TREM2
triggering receptor expressed on myeloid cells 2
chr2_-_216241321 1.595 FN1
fibronectin 1
chr19_+_41257086 1.593 SNRPA
small nuclear ribonucleoprotein polypeptide A
chr17_+_9729380 1.588 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr3_-_50340979 1.588 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr1_+_45205533 1.587 KIF2C
kinesin family member 2C
chr7_-_100860991 1.576 NM_001084
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_+_48876285 1.576 NM_152319
C12orf54
chromosome 12 open reading frame 54
chr15_-_59665069 1.574 NM_004998
MYO1E
myosin IE
chr13_+_46039024 1.572 NM_031431
COG3
component of oligomeric golgi complex 3
chr1_+_183114214 1.561 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr6_-_32160637 1.552 GPSM3
G-protein signaling modulator 3
chr14_-_53417808 1.552 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr2_-_110371669 1.551 NM_144710
NM_178584
SEPT10

septin 10

chr6_-_111888520 1.548 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr1_+_32688013 1.540 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_192127591 1.539 NM_130782
RGS18
regulator of G-protein signaling 18
chr2_-_161056573 1.534 NM_000888
ITGB6
integrin, beta 6
chr1_-_27216784 1.534 NM_018066
GPN2
GPN-loop GTPase 2
chr6_-_131384321 1.533 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr1_-_109825683 1.531 PSRC1
proline/serine-rich coiled-coil 1
chr2_+_239756672 1.526 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr1_+_32688010 1.524 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr9_+_33750463 1.521 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr10_+_49892860 1.521 WDFY4
WDFY family member 4
chr7_+_86273867 1.519 GRM3
glutamate receptor, metabotropic 3
chr5_+_68530713 1.515 CDK7
cyclin-dependent kinase 7
chr7_+_134464161 1.511 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr15_-_91565685 1.510 NM_018668
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chr16_+_1583666 1.507 TMEM204
transmembrane protein 204
chr17_+_40610915 1.506 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr5_+_110074740 1.503 NM_138773
SLC25A46
solute carrier family 25, member 46
chr1_-_214724565 1.501 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr15_-_34610928 1.495 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr3_-_149095517 1.492 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr2_-_216259197 1.492 FN1
fibronectin 1
chr17_-_48262900 1.486 COL1A1
collagen, type I, alpha 1
chr12_+_107712151 1.485 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr6_+_151561094 1.475 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_159923961 1.470 NM_001146172
NM_001146173
NM_033438
SLAMF9


SLAM family member 9


chr12_+_53442732 1.469 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr7_+_134464417 1.468 CALD1
caldesmon 1
chr15_-_41624760 1.458 NM_007280
OIP5
Opa interacting protein 5
chr20_+_44044706 1.455 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr7_+_143078608 1.454 ZYX
zyxin
chr7_+_129847699 1.452 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr10_-_71930185 1.450 NM_001142648
NM_020150
SAR1A

SAR1 homolog A (S. cerevisiae)

chr17_-_39507055 1.450 NM_004138
KRT33A
keratin 33A
chr5_-_127873734 1.448 NM_001999
FBN2
fibrillin 2
chr1_+_40506449 1.446 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr12_-_47473424 1.444 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr7_+_93551015 1.443 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr7_+_86274076 1.435 GRM3
glutamate receptor, metabotropic 3
chr11_+_5617330 1.432 NM_058166
TRIM6
tripartite motif containing 6
chr5_+_68530621 1.432 NM_001799
CDK7
cyclin-dependent kinase 7
chr1_+_40506406 1.431 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_88411948 1.421 AKIRIN2
akirin 2
chr2_-_9563584 1.412 ITGB1BP1
integrin beta 1 binding protein 1
chr3_-_139258373 1.408 RBP1
retinol binding protein 1, cellular
chr3_-_149095458 1.406 TM4SF1
transmembrane 4 L six family member 1
chrX_-_153775427 1.404 G6PD
glucose-6-phosphate dehydrogenase
chr15_+_69706619 1.400 NM_004856
NM_138555
KIF23

kinesin family member 23


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 1.68e-20 GO:0009987 cellular process
1.19 1.67e-11 GO:0043170 macromolecule metabolic process
1.20 2.69e-11 GO:0044260 cellular macromolecule metabolic process
1.21 5.66e-11 GO:0051716 cellular response to stimulus
1.23 3.04e-10 GO:0007165 signal transduction
1.21 2.07e-09 GO:0023052 signaling
1.22 8.32e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 1.03e-06 GO:0065007 biological regulation
1.13 1.83e-06 GO:0050896 response to stimulus
1.12 2.02e-06 GO:0044238 primary metabolic process
1.23 2.16e-06 GO:0006950 response to stress
1.19 2.50e-06 GO:0071840 cellular component organization or biogenesis
1.23 3.29e-06 GO:0044267 cellular protein metabolic process
1.28 4.69e-06 GO:0009059 macromolecule biosynthetic process
1.11 5.30e-06 GO:0050789 regulation of biological process
1.28 5.39e-06 GO:0034645 cellular macromolecule biosynthetic process
1.21 6.99e-06 GO:0048518 positive regulation of biological process
1.33 1.02e-05 GO:0002376 immune system process
1.26 1.37e-05 GO:0048583 regulation of response to stimulus
1.23 1.67e-05 GO:0090304 nucleic acid metabolic process
1.21 1.73e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.11 1.83e-05 GO:0050794 regulation of cellular process
1.18 4.95e-05 GO:0016043 cellular component organization
1.25 6.18e-05 GO:0010467 gene expression
1.21 9.28e-05 GO:0048522 positive regulation of cellular process
1.25 1.16e-04 GO:0007166 cell surface receptor linked signaling pathway
1.18 1.17e-04 GO:0019538 protein metabolic process
1.11 1.78e-04 GO:0044237 cellular metabolic process
1.49 2.02e-04 GO:0007010 cytoskeleton organization
1.46 4.94e-04 GO:0006935 chemotaxis
1.46 4.94e-04 GO:0042330 taxis
1.19 4.98e-04 GO:0071842 cellular component organization at cellular level
1.37 6.61e-04 GO:0016192 vesicle-mediated transport
1.46 7.14e-04 GO:0001775 cell activation
1.09 8.87e-04 GO:0008152 metabolic process
1.45 1.35e-03 GO:0007599 hemostasis
1.44 1.46e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.23 1.71e-03 GO:0016070 RNA metabolic process
1.63 1.97e-03 GO:0030036 actin cytoskeleton organization
1.16 2.08e-03 GO:0006807 nitrogen compound metabolic process
1.19 2.21e-03 GO:0048519 negative regulation of biological process
1.35 2.28e-03 GO:0006955 immune response
1.16 2.30e-03 GO:0034641 cellular nitrogen compound metabolic process
1.26 2.88e-03 GO:0035556 intracellular signal transduction
1.41 3.04e-03 GO:0050878 regulation of body fluid levels
1.38 3.35e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.40 3.36e-03 GO:0006944 cellular membrane fusion
1.43 4.31e-03 GO:0007596 blood coagulation
1.43 4.31e-03 GO:0050817 coagulation
1.81 4.81e-03 GO:0006184 GTP catabolic process
1.39 5.33e-03 GO:0042060 wound healing
1.31 5.45e-03 GO:0009611 response to wounding
1.54 6.26e-03 GO:0006412 translation
1.31 8.30e-03 GO:0040011 locomotion
1.44 8.38e-03 GO:0016044 cellular membrane organization
2.31 9.42e-03 GO:0061025 membrane fusion
1.75 9.65e-03 GO:0046039 GTP metabolic process
1.44 1.06e-02 GO:0002684 positive regulation of immune system process
1.64 1.07e-02 GO:0071843 cellular component biogenesis at cellular level
1.66 1.08e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.43 1.12e-02 GO:0061024 membrane organization
1.54 1.28e-02 GO:0030029 actin filament-based process
1.22 1.49e-02 GO:0006996 organelle organization
1.42 1.88e-02 GO:0050776 regulation of immune response
1.20 1.95e-02 GO:0006464 protein modification process
1.45 2.01e-02 GO:0007264 small GTPase mediated signal transduction
1.44 2.10e-02 GO:0016032 viral reproduction
1.47 2.47e-02 GO:0051301 cell division
1.26 2.47e-02 GO:0008104 protein localization
1.19 3.44e-02 GO:0043412 macromolecule modification
1.29 3.83e-02 GO:0015031 protein transport
1.18 4.05e-02 GO:0048523 negative regulation of cellular process
1.23 4.33e-02 GO:0033036 macromolecule localization
1.30 4.35e-02 GO:0022402 cell cycle process
1.26 4.47e-02 GO:0007049 cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 5.51e-15 GO:0005737 cytoplasm
1.32 1.18e-12 GO:0005829 cytosol
1.07 6.16e-10 GO:0005622 intracellular
1.08 7.37e-10 GO:0044424 intracellular part
1.14 2.48e-09 GO:0044444 cytoplasmic part
1.21 3.99e-07 GO:0043228 non-membrane-bounded organelle
1.21 3.99e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.17 1.56e-06 GO:0032991 macromolecular complex
1.23 1.57e-06 GO:0044428 nuclear part
1.12 1.54e-05 GO:0044422 organelle part
1.18 3.21e-05 GO:0043234 protein complex
1.12 3.90e-05 GO:0044446 intracellular organelle part
1.23 4.61e-05 GO:0031981 nuclear lumen
1.20 1.18e-04 GO:0043233 organelle lumen
1.19 2.47e-04 GO:0031974 membrane-enclosed lumen
1.19 3.22e-04 GO:0070013 intracellular organelle lumen
1.06 5.77e-04 GO:0043229 intracellular organelle
1.06 6.50e-04 GO:0043226 organelle
1.90 1.09e-03 GO:0030055 cell-substrate junction
1.89 2.18e-03 GO:0005924 cell-substrate adherens junction
1.90 3.16e-03 GO:0005925 focal adhesion
1.03 9.96e-03 GO:0044464 cell part
1.09 9.98e-03 GO:0005634 nucleus
1.03 1.05e-02 GO:0005623 cell
1.20 1.08e-02 GO:0005856 cytoskeleton
1.61 1.11e-02 GO:0031252 cell leading edge
1.21 2.19e-02 GO:0005654 nucleoplasm
1.64 2.53e-02 GO:0005912 adherens junction
1.87 2.59e-02 GO:0030027 lamellipodium
2.01 4.23e-02 GO:0015934 large ribosomal subunit
1.61 4.80e-02 GO:0044445 cytosolic part
1.84 4.93e-02 GO:0046930 pore complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 6.01e-27 GO:0005515 protein binding
1.06 5.10e-06 GO:0005488 binding
2.68 1.18e-05 GO:0005070 SH3/SH2 adaptor activity
2.40 8.81e-05 GO:0035591 signaling adaptor activity
1.93 1.17e-04 GO:0060090 binding, bridging
1.95 1.72e-04 GO:0030674 protein binding, bridging
1.55 3.96e-04 GO:0003779 actin binding
1.50 5.88e-04 GO:0019001 guanyl nucleotide binding
1.50 5.88e-04 GO:0032561 guanyl ribonucleotide binding
1.49 1.00e-03 GO:0005525 GTP binding
1.39 1.88e-03 GO:0008092 cytoskeletal protein binding
1.59 9.16e-03 GO:0003924 GTPase activity
1.28 1.98e-02 GO:0003723 RNA binding