Motif ID: FOXL1.p2

Z-value: 1.164


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXL1chr16_+_86612114-0.271.5e-01Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_50589389 8.255 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr1_+_104159953 8.183 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr5_+_94727047 7.993 NM_152548
FAM81B
family with sequence similarity 81, member B
chr3_-_12941547 6.992 IQSEC1
IQ motif and Sec7 domain 1
chr20_+_9288446 5.228 NM_000933
PLCB4
phospholipase C, beta 4
chrX_-_117119282 4.222 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr1_-_161337663 4.075 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr20_+_9458460 4.073 PLCB4
phospholipase C, beta 4
chr16_+_19467771 4.061 NM_024780
TMC5
transmembrane channel-like 5
chr5_+_156696351 4.052 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_-_183622447 3.985 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr4_-_84035888 3.839 PLAC8
placenta-specific 8
chr5_-_137475076 3.773 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr12_+_69742140 3.496 LYZ
lysozyme
chr10_+_115511212 3.370 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr10_+_94594469 3.312 NM_001013848
EXOC6
exocyst complex component 6
chr3_-_148939784 3.309 NM_000096
CP
ceruloplasmin (ferroxidase)
chr4_-_84035908 3.303 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr2_+_24807345 3.210 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr4_-_110723127 3.202 CFI
complement factor I
chr3_+_361365 3.068 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr9_-_75568232 3.006 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_-_41261539 2.960 NM_001115131
C6
complement component 6
chr14_-_106774311 2.925 IGHA1
immunoglobulin heavy constant alpha 1
chr7_+_116660291 2.925 ST7
suppression of tumorigenicity 7
chr16_-_23724820 2.824 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr18_-_24722757 2.817 NM_001243848
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr2_-_135782246 2.778 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr5_+_139505519 2.774 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr8_-_102803196 2.619 NCALD
neurocalcin delta
chr5_+_140165875 2.606 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr9_-_75567915 2.600 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_+_244214576 2.597 ZNF238
zinc finger protein 238
chr6_-_32557431 2.570 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr3_+_113616317 2.476 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr11_+_99426872 2.475 NM_175566
CNTN5
contactin 5
chr12_+_41831484 2.471 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr12_+_131438451 2.430 NM_198827
GPR133
G protein-coupled receptor 133
chr5_+_140261792 2.327 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr10_+_96522457 2.247 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr5_-_16509106 2.203 NM_019000
FAM134B
family with sequence similarity 134, member B
chr19_-_14992166 2.198 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr13_-_39564857 2.191 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr1_-_152131703 2.169 NM_001122965
RPTN
repetin
chr5_+_42548144 2.166 NM_001242402
GHR
growth hormone receptor
chr8_+_76452202 2.163 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr1_-_150738292 2.144 NM_001199739
NM_004079
CTSS

cathepsin S

chr9_-_3223007 2.138


chr17_+_26800657 2.101 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr17_-_34328530 2.041 CCL14-CCL15
CCL15
CCL14-CCL15 readthrough
chemokine (C-C motif) ligand 15
chr4_+_187070326 2.001 NM_001006655
FAM149A
family with sequence similarity 149, member A
chr5_+_140213968 2.000 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr13_+_24144402 1.958 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr8_-_102803438 1.935 NM_032041
NCALD
neurocalcin delta
chr11_+_6897855 1.902 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr4_-_100356449 1.890 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr19_+_41594367 1.870 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr3_+_171561138 1.854 NM_001164436
TMEM212
transmembrane protein 212
chr5_-_110062365 1.836 NM_001039763
TMEM232
transmembrane protein 232
chr17_-_34329083 1.812 NM_032965
CCL15
chemokine (C-C motif) ligand 15
chr16_+_82068910 1.806 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr22_+_29449877 1.801 ZNRF3
zinc and ring finger 3
chr12_+_69742130 1.795 NM_000239
LYZ
lysozyme
chr7_-_16921596 1.789 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr10_-_116444374 1.774 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_116444112 1.749 ABLIM1
actin binding LIM protein 1
chr1_+_114493766 1.735 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr5_+_42548314 1.666 NM_001242403
GHR
growth hormone receptor
chr15_+_78558522 1.632 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr10_+_96443250 1.590 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr1_-_207095198 1.586 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr4_-_110723334 1.565 NM_000204
CFI
complement factor I
chr3_+_132318980 1.547 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr4_+_70861647 1.499 NM_001009181
NM_003154
STATH

statherin

chr14_-_20774129 1.488 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr5_+_140186658 1.476 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr1_+_196621007 1.457 NM_000186
NM_001014975
CFH

complement factor H

chr11_+_17332454 1.417


chr18_+_61582744 1.400 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr1_+_244214552 1.393 NM_205768
ZNF238
zinc finger protein 238
chr17_+_68071386 1.387 NM_018658
NM_170741
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr15_-_90349819 1.354 ANPEP
alanyl (membrane) aminopeptidase
chr3_-_151102536 1.341 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr1_+_104097321 1.319 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr4_+_72102249 1.307 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr7_+_23286384 1.299 GPNMB
glycoprotein (transmembrane) nmb
chr10_-_62149487 1.287 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_-_116418056 1.281 NM_002313
ABLIM1
actin binding LIM protein 1
chr5_+_156820161 1.276 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_114790221 1.266 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_26724748 1.240 ADRA1A
adrenergic, alpha-1A-, receptor
chr5_-_41213513 1.232 NM_000065
C6
complement component 6
chr8_+_105352050 1.231 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr8_-_110620220 1.222 SYBU
syntabulin (syntaxin-interacting)
chr5_+_140602914 1.213 NM_018934
PCDHB14
protocadherin beta 14
chrX_+_37865834 1.195 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr8_+_40010986 1.195 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr3_-_25683825 1.177 TOP2B
topoisomerase (DNA) II beta 180kDa
chr6_-_55740358 1.162 NM_021073
BMP5
bone morphogenetic protein 5
chr4_+_41700736 1.161 LIMCH1
LIM and calponin homology domains 1
chr7_+_23286277 1.120 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr5_-_42811959 1.113 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr1_+_236681513 1.109 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr3_-_93747453 1.107 NM_001001850
STX19
syntaxin 19
chr11_+_73661363 1.099 NM_153614
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr8_-_110661007 1.095 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr14_+_21156922 1.088 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr4_+_76995862 1.084 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr6_+_19837599 1.082 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr7_+_90338711 1.076 NM_012395
CDK14
cyclin-dependent kinase 14
chrX_+_36254050 1.073 NM_001098843
CXorf30
chromosome X open reading frame 30
chr7_+_89843133 1.066 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr9_-_117265452 1.056 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr12_-_86230158 1.035 NM_005447
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr8_-_102803178 1.032 NCALD
neurocalcin delta
chr1_-_150738232 1.032 CTSS
cathepsin S
chr20_+_51801821 1.015 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr6_-_55740387 1.013 BMP5
bone morphogenetic protein 5
chr3_-_151058439 1.012 NM_176876
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr11_+_71903172 1.012 NM_016729
FOLR1
folate receptor 1 (adult)
chr5_+_36608430 1.002 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrM_+_12283 1.001


chr3_+_132316080 0.980 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr13_+_111855406 0.976 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_23891608 0.975 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_+_85766286 0.973 MAT2A
methionine adenosyltransferase II, alpha
chr2_-_217560247 0.960 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr6_-_134498973 0.960 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_29624249 0.956 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr7_-_112727832 0.937 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr2_+_38155901 0.930 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr3_-_121379757 0.926 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_216978708 0.919 NM_001243514
ESRRG
estrogen-related receptor gamma
chr1_+_167298382 0.915 POU2F1
POU class 2 homeobox 1
chr20_-_34117447 0.911 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr14_-_106641585 0.897 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_59775749 0.897 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr11_-_59633942 0.889 NM_001062
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr4_-_100356290 0.888 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_72667089 0.878 NM_005193
CDX4
caudal type homeobox 4
chr2_+_61389628 0.872 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr21_-_35884503 0.872 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr7_-_112727778 0.867 GPR85
G protein-coupled receptor 85
chr6_-_76203256 0.866 NM_015687
FILIP1
filamin A interacting protein 1
chr1_-_183274008 0.861 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr17_-_34328607 0.861 CCL14-CCL15
CCL14-CCL15 readthrough
chr14_-_23285011 0.857 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr20_+_19915716 0.852 RIN2
Ras and Rab interactor 2
chr4_+_69962191 0.849 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_+_23352430 0.843 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr8_+_17822093 0.842 PCM1
pericentriolar material 1
chr11_+_7618416 0.839 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_57045129 0.826 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_57530067 0.826 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr1_-_150738255 0.821 CTSS
cathepsin S
chr1_-_86043932 0.821 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_24103953 0.817 SOX5
SRY (sex determining region Y)-box 5
chr11_+_10476665 0.809 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chrX_-_77914824 0.808 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr5_+_140514787 0.808 NM_015669
PCDHB5
protocadherin beta 5
chrX_+_22050920 0.805 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr5_+_53751430 0.803 NM_006308
HSPB3
heat shock 27kDa protein 3
chr10_-_94003002 0.803 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr3_-_193272587 0.798 NM_032279
ATP13A4
ATPase type 13A4
chr9_+_273025 0.795 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr10_+_95848811 0.789 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr9_+_127119114 0.779


chrX_+_57313109 0.776 NM_174912
FAAH2
fatty acid amide hydrolase 2
chr6_+_20534686 0.773 NM_017774
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr7_+_94539209 0.772 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr4_-_186300151 0.770 NM_018409
LRP2BP
LRP2 binding protein
chr11_+_65266642 0.766


chr19_+_16059817 0.765 NM_001004465
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr3_+_108541544 0.762 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr10_-_61900659 0.753 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_144612872 0.753 NM_007124
UTRN
utrophin
chr2_-_86565205 0.752 NM_001164730
REEP1
receptor accessory protein 1
chr6_-_139613114 0.744 NM_153235
TXLNB
taxilin beta
chr11_-_1629614 0.744 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr6_-_46889620 0.740 NM_001098518
GPR116
G protein-coupled receptor 116
chr7_+_30951414 0.735 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_-_76076762 0.734 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr7_-_92855780 0.729 NM_001039372
HEPACAM2
HEPACAM family member 2
chr17_+_72429835 0.728 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr4_+_106067031 0.724 NM_017628
TET2
tet methylcytosine dioxygenase 2
chr3_-_52713728 0.717 NM_018165
NM_181042
PBRM1

polybromo 1

chr7_+_48211054 0.716 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr1_+_79115476 0.714 NM_006417
IFI44
interferon-induced protein 44
chr17_+_32683470 0.711 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr3_-_121379701 0.706 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr15_-_44969085 0.706 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr7_-_112727799 0.704 GPR85
G protein-coupled receptor 85
chr7_-_99680170 0.703


chrX_-_132162297 0.703 NM_031907
USP26
ubiquitin specific peptidase 26
chr17_-_10421858 0.702 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chrM_+_9182 0.702


chrM_+_9217 0.700


chr12_+_109826523 0.700 NM_001101421
MYO1H
myosin IH
chr1_+_151129104 0.699 NM_001204848
NM_024575
TNFAIP8L2-SCNM1
TNFAIP8L2
TNFAIP8L2-SCNM1 readthrough
tumor necrosis factor, alpha-induced protein 8-like 2
chr6_-_136847078 0.699 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.41 5.12e-04 GO:0007156 homophilic cell adhesion
2.44 2.46e-03 GO:0016337 cell-cell adhesion
12.13 3.90e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.56 4.30e-06 GO:0005576 extracellular region
1.83 5.48e-06 GO:0044421 extracellular region part
1.82 2.73e-04 GO:0005615 extracellular space
2.85 2.93e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.50 1.13e-02 GO:0005125 cytokine activity
2.10 1.84e-02 GO:0003779 actin binding