Motif ID: FOXN1.p2

Z-value: 2.167


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXN1chr17_+_268509580.077.0e-01Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_9479943 10.997 NM_001080556
NM_145054
 WDR16

WD repeat domain 16

chr2_-_28113211 10.489 NM_022128
 RBKS
ribokinase
chr15_+_71184781 9.925 NM_001199017
NM_017691
NM_001199018
 LRRC49


leucine rich repeat containing 49


chr14_+_65016613 9.748 NM_172365
 PPP1R36
protein phosphatase 1, regulatory subunit 36
chr6_-_24911194 9.235 NM_014722
 FAM65B
family with sequence similarity 65, member B
chr17_-_74137370 9.004 NM_001454
 FOXJ1
forkhead box J1
chr6_-_32551993 8.588 HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr11_+_101918168 8.572 NM_001195005
NM_032930
 C11orf70

chromosome 11 open reading frame 70

chr13_+_24734788 8.484 NM_001166271
NM_153023
 SPATA13

spermatogenesis associated 13

chr16_+_4784261 8.342 NM_139170
 C16orf71
chromosome 16 open reading frame 71
chr22_+_45809599 8.243 RIBC2
RIB43A domain with coiled-coils 2
chr2_-_110962577 7.644 NM_000272
NM_001128178
NM_001128179
NM_207181
 NPHP1



nephronophthisis 1 (juvenile)



chr22_+_45809541 7.626 NM_015653
 RIBC2
RIB43A domain with coiled-coils 2
chr17_+_11501747 7.288 NM_001372
 DNAH9
dynein, axonemal, heavy chain 9
chr5_-_100238870 7.139 NM_175052
NM_005668
 ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr3_+_158288952 7.037 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
 MLF1





myeloid leukemia factor 1





chr7_-_120498009 6.913 TSPAN12
tetraspanin 12
chr9_+_72435730 6.461 NM_001010940
 C9orf135
chromosome 9 open reading frame 135
chr12_-_68726036 6.165 NM_001205028
NM_001205029
NM_017440
NM_020128
 MDM1



Mdm1 nuclear protein homolog (mouse)



chr17_-_6735007 6.076 NM_053285
 TEKT1
tektin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
2.28 2.50e-05 GO:0016568 chromatin modification
2.05 1.28e-04 GO:0006325 chromatin organization
1.98 1.11e-05 GO:0051276 chromosome organization
1.90 3.23e-02 GO:0006397 mRNA processing
1.85 3.94e-03 GO:0044265 cellular macromolecule catabolic process
1.80 1.13e-02 GO:0016071 mRNA metabolic process
1.62 9.80e-03 GO:0006351 transcription, DNA-dependent
1.55 1.06e-05 GO:0016070 RNA metabolic process
1.55 2.88e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.48 4.45e-06 GO:0090304 nucleic acid metabolic process
1.48 1.46e-03 GO:0006996 organelle organization
1.45 8.64e-04 GO:0010467 gene expression
1.43 3.74e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 5.59e-04 GO:0006355 regulation of transcription, DNA-dependent
1.40 6.22e-04 GO:0051252 regulation of RNA metabolic process
1.40 7.95e-03 GO:0043412 macromolecule modification
1.39 1.32e-10 GO:0044260 cellular macromolecule metabolic process
1.37 1.12e-03 GO:0010468 regulation of gene expression
1.37 2.45e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.34 2.70e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
3.66 1.79e-03 GO:0016363 nuclear matrix
3.34 6.44e-03 GO:0034399 nuclear periphery
2.25 2.52e-02 GO:0044454 nuclear chromosome part
2.09 3.14e-02 GO:0000228 nuclear chromosome
1.82 1.55e-05 GO:0044451 nucleoplasm part
1.78 3.16e-10 GO:0005654 nucleoplasm
1.70 4.32e-12 GO:0031981 nuclear lumen
1.60 2.60e-11 GO:0070013 intracellular organelle lumen
1.60 5.23e-11 GO:0044428 nuclear part
1.57 1.27e-10 GO:0043233 organelle lumen
1.57 1.27e-10 GO:0031974 membrane-enclosed lumen
1.42 5.17e-19 GO:0005634 nucleus
1.27 1.85e-18 GO:0043227 membrane-bounded organelle
1.27 2.30e-18 GO:0043231 intracellular membrane-bounded organelle
1.25 1.99e-06 GO:0044446 intracellular organelle part
1.24 5.21e-06 GO:0044422 organelle part
1.22 9.71e-15 GO:0043226 organelle
1.21 1.57e-14 GO:0043229 intracellular organelle
1.17 1.04e-14 GO:0044424 intracellular part
1.17 2.87e-14 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.66 7.42e-04 GO:0003723 RNA binding
1.59 3.86e-02 GO:0043565 sequence-specific DNA binding
1.50 2.21e-02 GO:0001071 nucleic acid binding transcription factor activity
1.50 2.21e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 2.39e-10 GO:0003676 nucleic acid binding
1.44 4.08e-06 GO:0003677 DNA binding
1.32 1.01e-02 GO:0000166 nucleotide binding
1.10 3.58e-04 GO:0005488 binding