Motif ID: GATA1..3.p2

Z-value: 1.535


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA2chr3_-_1282120270.461.1e-02Click!
GATA3chr10_+_80967720.183.3e-01Click!
GATA1chrX_+_48644961-0.086.6e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_3405888 3.508 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr12_+_53818864 2.168 AMHR2
anti-Mullerian hormone receptor, type II
chr16_+_89778242 2.146 LOC100128881
uncharacterized LOC100128881
chr2_-_209010876 1.845 NM_005210
CRYGB
crystallin, gamma B
chr17_-_62050200 1.730 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chr2_-_216241321 1.530 FN1
fibronectin 1
chr2_-_29297126 1.393 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr8_-_121823696 1.239 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr9_-_35958095 1.221 NM_019897
OR2S2
olfactory receptor, family 2, subfamily S, member 2
chr4_+_134073180 1.196 PCDH10
protocadherin 10
chr2_-_51259239 1.186 NRXN1
neurexin 1
chr7_+_27135672 1.179 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr6_-_46825942 1.122 GPR116
G protein-coupled receptor 116
chr8_+_110099652 1.106 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr12_+_1738411 1.100 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr22_+_38219388 1.085 NM_003614
GALR3
galanin receptor 3
chr1_-_161519817 1.071 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr11_+_76813884 1.051 NM_006189
OMP
olfactory marker protein
chr17_+_36861398 1.037 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr4_-_138453628 0.958 NM_019035
PCDH18
protocadherin 18

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 88 entries
enrichment   p-value GO term description
2.55 3.33e-02 GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity
2.35 3.14e-06 GO:0019080 viral genome expression
2.35 3.14e-06 GO:0019083 viral transcription
2.30 4.40e-07 GO:0006414 translational elongation
2.27 1.42e-05 GO:0006415 translational termination
2.17 8.43e-07 GO:0031018 endocrine pancreas development
2.15 6.68e-05 GO:0043241 protein complex disassembly
2.15 6.68e-05 GO:0043624 cellular protein complex disassembly
2.11 9.07e-10 GO:0035270 endocrine system development
2.08 5.81e-07 GO:0031016 pancreas development
2.03 2.51e-04 GO:0032984 macromolecular complex disassembly
2.03 2.51e-04 GO:0034623 cellular macromolecular complex disassembly
1.98 6.11e-03 GO:0006334 nucleosome assembly
1.98 3.56e-02 GO:0048706 embryonic skeletal system development
1.93 4.19e-03 GO:0065004 protein-DNA complex assembly
1.92 8.38e-03 GO:0034728 nucleosome organization
1.90 4.04e-03 GO:0071824 protein-DNA complex subunit organization
1.88 9.27e-04 GO:0019058 viral infectious cycle
1.88 3.25e-02 GO:0031497 chromatin assembly
1.86 1.51e-04 GO:0022415 viral reproductive process

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.90 1.55e-02 GO:0005891 voltage-gated calcium channel complex
2.55 2.44e-02 GO:0034704 calcium channel complex
2.32 2.08e-04 GO:0000786 nucleosome
2.05 2.38e-03 GO:0022626 cytosolic ribosome
1.83 3.26e-04 GO:0034703 cation channel complex
1.83 1.67e-02 GO:0032993 protein-DNA complex
1.59 6.72e-07 GO:0043005 neuron projection
1.58 3.03e-02 GO:0043025 neuronal cell body
1.57 8.27e-03 GO:0034702 ion channel complex
1.57 1.82e-02 GO:0030425 dendrite
1.47 5.55e-03 GO:0044433 cytoplasmic vesicle part
1.46 7.96e-04 GO:0045202 synapse
1.45 2.33e-02 GO:0044456 synapse part
1.36 9.90e-06 GO:0042995 cell projection
1.27 2.06e-02 GO:0005615 extracellular space
1.25 6.04e-03 GO:0044421 extracellular region part
1.17 5.05e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.90 7.41e-03 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
2.78 1.62e-02 GO:0004112 cyclic-nucleotide phosphodiesterase activity
1.90 4.42e-05 GO:0022843 voltage-gated cation channel activity
1.82 4.32e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.70 6.97e-04 GO:0005244 voltage-gated ion channel activity
1.70 6.97e-04 GO:0022832 voltage-gated channel activity
1.58 6.59e-04 GO:0005261 cation channel activity
1.57 1.49e-04 GO:0022836 gated channel activity
1.51 4.75e-05 GO:0015267 channel activity
1.51 5.65e-05 GO:0022803 passive transmembrane transporter activity
1.49 2.26e-04 GO:0022838 substrate-specific channel activity
1.49 2.70e-04 GO:0005216 ion channel activity
1.34 2.71e-03 GO:0043565 sequence-specific DNA binding
1.34 6.88e-03 GO:0005198 structural molecule activity
1.32 3.03e-05 GO:0005102 receptor binding
1.30 4.10e-04 GO:0001071 nucleic acid binding transcription factor activity
1.30 4.10e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.27 2.66e-03 GO:0030528 transcription regulator activity
1.12 7.04e-09 GO:0005515 protein binding
1.04 2.65e-02 GO:0005488 binding