Motif ID: GATA6.p2

Z-value: 0.987


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_197494030.346.5e-02Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_33795558 2.594 NM_002771
 PRSS3
protease, serine, 3
chr1_-_153044083 2.332 NM_001017418
 SPRR2B
small proline-rich protein 2B
chrX_+_37865834 2.331 NM_001163335
NM_138780
 SYTL5

synaptotagmin-like 5

chr8_+_54764367 2.126 NM_170587
 RGS20
regulator of G-protein signaling 20
chr1_-_205391180 2.015 NM_001001552
NM_001199050
NM_001199051
NM_001199052
 LEMD1



LEM domain containing 1



chr8_+_124194751 1.825 NM_032899
NM_207006
 FAM83A

family with sequence similarity 83, member A

chr2_+_27719702 1.795 NM_001486
 GCKR
glucokinase (hexokinase 4) regulator
chr12_-_91505541 1.716 NM_002345
 LUM
lumican
chr1_-_24469571 1.660 NM_021258
 IL22RA1
interleukin 22 receptor, alpha 1
chr4_-_159093717 1.637 NM_016613
 FAM198B
family with sequence similarity 198, member B
chr4_-_159094163 1.534 NM_001031700
NM_001128424
 FAM198B

family with sequence similarity 198, member B

chr4_+_169013687 1.522 NM_007193
 ANXA10
annexin A10
chr8_+_124194873 1.505 FAM83A
family with sequence similarity 83, member A
chr9_+_33240165 1.463 NM_014471
 SPINK4
serine peptidase inhibitor, Kazal type 4
chr11_-_58343308 1.447 NM_004811
 LPXN
leupaxin
chr7_+_142457318 1.417 NM_002769
 PRSS1
PRSS2
protease, serine, 1 (trypsin 1)
protease, serine, 2 (trypsin 2)
chr3_-_137851123 1.367 NM_016161
 A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr7_-_100239136 1.360 NM_003227
 TFR2
transferrin receptor 2
chr12_+_107974633 1.332 NM_001017523
 BTBD11
BTB (POZ) domain containing 11
chr11_-_124310980 1.184 NM_012378
 OR8B8
olfactory receptor, family 8, subfamily B, member 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 60 entries
enrichment   p-value GO term description
17.43 4.52e-02 GO:0006705 mineralocorticoid biosynthetic process
17.43 4.52e-02 GO:0008212 mineralocorticoid metabolic process
13.62 2.14e-02 GO:0006704 glucocorticoid biosynthetic process
10.90 1.43e-02 GO:0008211 glucocorticoid metabolic process
10.90 1.43e-02 GO:0044241 lipid digestion
9.53 7.15e-03 GO:0006700 C21-steroid hormone biosynthetic process
8.97 1.17e-02 GO:0050892 intestinal absorption
7.85 1.97e-03 GO:0008207 C21-steroid hormone metabolic process
6.46 4.18e-02 GO:0050886 endocrine process
5.32 2.61e-02 GO:0006721 terpenoid metabolic process
4.94 8.08e-05 GO:0034754 cellular hormone metabolic process
4.87 2.72e-06 GO:0007586 digestion
4.67 1.11e-03 GO:0042446 hormone biosynthetic process
4.36 2.83e-03 GO:0002576 platelet degranulation
3.96 3.56e-06 GO:0042445 hormone metabolic process
3.56 2.05e-02 GO:0006694 steroid biosynthetic process
3.50 4.60e-06 GO:0010817 regulation of hormone levels
3.48 2.35e-07 GO:0008202 steroid metabolic process
3.44 1.54e-03 GO:0006805 xenobiotic metabolic process
3.44 1.54e-03 GO:0071466 cellular response to xenobiotic stimulus

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.64 1.42e-02 GO:0031093 platelet alpha granule lumen
4.61 6.29e-03 GO:0031983 vesicle lumen
4.54 1.72e-02 GO:0034774 secretory granule lumen
4.36 2.49e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
4.21 1.56e-02 GO:0031091 platelet alpha granule
2.62 5.52e-03 GO:0030141 stored secretory granule
2.60 2.50e-14 GO:0005615 extracellular space
2.34 8.54e-14 GO:0044421 extracellular region part
2.07 7.63e-20 GO:0005576 extracellular region
1.47 8.34e-04 GO:0044459 plasma membrane part
1.38 2.14e-06 GO:0071944 cell periphery
1.37 1.46e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
8.17 2.46e-02 GO:0008395 steroid hydroxylase activity
4.02 1.74e-02 GO:0005496 steroid binding
3.51 2.00e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.30 2.22e-02 GO:0005179 hormone activity
2.91 1.37e-03 GO:0005126 cytokine receptor binding
2.81 1.59e-03 GO:0005125 cytokine activity
2.40 1.85e-05 GO:0008289 lipid binding
1.83 6.27e-05 GO:0005102 receptor binding