Motif ID: GCUACAU

Z-value: 0.427


Mature miRNA associated with seed GCUACAU:

NamemiRBase Accession
hsa-miR-221 MIMAT0000278
hsa-miR-222 MIMAT0000279



Activity profile for motif GCUACAU.

activity profile for motif GCUACAU


Sorted Z-values histogram for motif GCUACAU

Sorted Z-values for motif GCUACAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUACAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_40398286 0.792 NM_001003942
NM_001003943
 BMF

Bcl2 modifying factor

chr15_-_40398573 0.781 NM_033503
 BMF
Bcl2 modifying factor
chr15_-_40401041 0.723 NM_001003940
 BMF
Bcl2 modifying factor
chr4_+_72052354 0.699 NM_001098484
NM_001134742
 SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr6_+_16129285 0.572 NM_013262
 MYLIP
myosin regulatory light chain interacting protein
chr16_+_28303622 0.572 NM_001024401
 SBK1
SH3-binding domain kinase 1
chr3_-_145968958 0.518 NM_001128306
NM_001177304
NM_020353
 PLSCR4


phospholipid scramblase 4


chr4_+_72204769 0.479 NM_003759
 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr4_+_55523906 0.453 NM_000222
NM_001093772
 KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr1_+_114496498 0.427 NM_181358
 HIPK1
homeodomain interacting protein kinase 1
chr1_+_114493766 0.420 NM_198269
 HIPK1
homeodomain interacting protein kinase 1
chrX_-_44202834 0.375 NM_025184
 EFHC2
EF-hand domain (C-terminal) containing 2
chr17_-_47439326 0.357 NM_001145365
NM_014897
 ZNF652

zinc finger protein 652

chr7_+_114055048 0.338 NM_001172766
NM_014491
NM_148898
NM_148900
 FOXP2



forkhead box P2



chr6_-_56112315 0.331 NM_030820
 COL21A1
collagen, type XXI, alpha 1
chr5_+_140254930 0.307 NM_018903
NM_031864
 PCDHA12

protocadherin alpha 12

chr5_+_140213968 0.305 NM_018910
NM_031852
 PCDHA7

protocadherin alpha 7

chr14_+_74111577 0.301 NM_001201366
NM_031427
 DNAL1

dynein, axonemal, light chain 1

chr5_+_140220811 0.300 NM_018911
NM_031856
 PCDHA8

protocadherin alpha 8

chr5_+_140186658 0.295 NM_018907
NM_031500
 PCDHA4

protocadherin alpha 4


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
4.74 3.79e-04 GO:0007156 homophilic cell adhesion
3.06 5.18e-03 GO:0016337 cell-cell adhesion
3.00 1.94e-02 GO:0010608 posttranscriptional regulation of gene expression
2.43 7.68e-03 GO:0051253 negative regulation of RNA metabolic process
2.42 2.92e-03 GO:0010629 negative regulation of gene expression
2.32 1.06e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32 3.65e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.29 1.37e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.20 3.96e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.18 9.48e-04 GO:0010605 negative regulation of macromolecule metabolic process
2.15 3.78e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.11 4.05e-03 GO:0031324 negative regulation of cellular metabolic process
2.10 1.44e-03 GO:0009892 negative regulation of metabolic process
1.61 2.09e-03 GO:0010468 regulation of gene expression
1.56 2.76e-02 GO:0048519 negative regulation of biological process
1.41 4.69e-03 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
7.77 2.43e-02 GO:0000932 cytoplasmic mRNA processing body
2.12 3.88e-03 GO:0044451 nucleoplasm part
1.77 5.62e-03 GO:0005654 nucleoplasm
1.42 2.63e-06 GO:0005634 nucleus
1.19 2.44e-02 GO:0043231 intracellular membrane-bounded organelle
1.19 2.67e-02 GO:0043227 membrane-bounded organelle
1.15 3.62e-03 GO:0005622 intracellular
1.14 1.07e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
15.53 2.52e-02 GO:0045295 gamma-catenin binding
6.04 4.41e-02 GO:0008013 beta-catenin binding
3.32 5.55e-04 GO:0003702 RNA polymerase II transcription factor activity
2.85 3.72e-03 GO:0016564 transcription repressor activity
2.30 3.55e-02 GO:0019904 protein domain specific binding
1.84 2.12e-02 GO:0030528 transcription regulator activity
1.50 3.00e-02 GO:0003677 DNA binding
1.49 7.10e-04 GO:0003676 nucleic acid binding
1.37 2.18e-02 GO:0046872 metal ion binding
1.36 2.36e-02 GO:0043169 cation binding
1.36 2.64e-02 GO:0043167 ion binding
1.30 8.61e-05 GO:0005515 protein binding
1.15 6.30e-04 GO:0005488 binding