Motif ID: GCUGGUG

Z-value: 0.489


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_36050885 0.753 NM_001204197
NBEA
neurobeachin
chr15_-_68498373 0.741 NM_001031733
NM_033429
CALML4

calmodulin-like 4

chr5_+_156696351 0.706 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_+_156693051 0.667 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr13_+_35516390 0.631 NM_015678
NBEA
neurobeachin
chr9_+_17578952 0.606 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr17_+_38498270 0.563 NM_001024809
RARA
retinoic acid receptor, alpha
chr20_+_36531498 0.547 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr20_-_3149070 0.489 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_+_40859016 0.484 NM_001198979
SMAP2
small ArfGAP2
chr1_+_40839368 0.472 NM_022733
SMAP2
small ArfGAP2
chr6_+_39760148 0.470 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr6_+_39760772 0.453 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr2_+_10184371 0.451 NM_001177718
KLF11
Kruppel-like factor 11
chr1_+_40840304 0.446 NM_001198978
SMAP2
small ArfGAP2
chr1_+_61547625 0.444 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61542928 0.416 NM_001145511
NFIA
nuclear factor I/A
chr1_+_40862471 0.415 NM_001198980
SMAP2
small ArfGAP2
chr4_+_52917440 0.406 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr4_+_41614911 0.403 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_61547388 0.382 NM_001145512
NFIA
nuclear factor I/A
chr2_+_10183630 0.378 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr4_+_41362750 0.373 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr20_+_43990576 0.352 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr19_+_13105970 0.350 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_108991893 0.346 NM_181724
TMEM119
transmembrane protein 119
chr3_-_13008959 0.325 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr15_-_43877043 0.322 NM_014659
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr19_-_14316980 0.314 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr13_-_52585472 0.306 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr5_-_114880536 0.304 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr11_+_58939539 0.296 NM_015177
DTX4
deltex homolog 4 (Drosophila)
chr4_-_23891608 0.291 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr20_+_42086468 0.290 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr11_+_100557851 0.284 NM_152432
ARHGAP42
Rho GTPase activating protein 42
chr15_-_43882387 0.283 NM_001130858
NM_001130859
NM_001190214
PPIP5K1


diphosphoinositol pentakisphosphate kinase 1


chr18_+_67956136 0.278 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr5_-_176057324 0.270 NM_001001502
NM_003085
SNCB

synuclein, beta

chr20_+_54933982 0.268 NM_080821
FAM210B
family with sequence similarity 210, member B
chrX_+_69674914 0.268 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chrX_+_9431314 0.263 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr18_-_45663667 0.255 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr15_-_48470453 0.255 NM_016132
MYEF2
myelin expression factor 2
chr1_+_26438267 0.255 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr11_-_115375065 0.255 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr18_-_53255734 0.253 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chrX_+_69664704 0.251 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr10_+_76586299 0.249 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr2_+_86947387 0.247 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr11_+_118978087 0.246 NM_014807
C2CD2L
C2CD2-like
chr16_+_58549382 0.246 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr2_+_148602569 0.242 NM_001616
ACVR2A
activin A receptor, type IIA
chr3_-_136471186 0.239 NM_005862
STAG1
stromal antigen 1
chr7_-_152133071 0.239 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_120189342 0.237 NM_183240
TMEM37
transmembrane protein 37
chr10_+_72163860 0.236 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr15_-_51914770 0.235 NM_001174116
NM_001174117
NM_015263
DMXL2


Dmx-like 2


chr10_+_69644938 0.233 NM_001142498
SIRT1
sirtuin 1
chr11_-_47600458 0.230 NM_016506
NM_018095
KBTBD4

kelch repeat and BTB (POZ) domain containing 4

chr15_-_74988342 0.227 NM_001142443
NM_001142444
NM_025083
EDC3


enhancer of mRNA decapping 3 homolog (S. cerevisiae)


chr2_-_85788644 0.225 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr16_+_69599868 0.222 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr17_-_56065596 0.220 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr6_+_41514133 0.220 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr6_+_87865261 0.219 NM_015021
ZNF292
zinc finger protein 292
chrX_+_69672110 0.216 NM_020730
DLG3
discs, large homolog 3 (Drosophila)
chr11_-_130184459 0.212 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr2_-_160472960 0.212 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr5_+_149151502 0.210 NM_001172699
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr11_-_129062092 0.210 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr3_+_23987514 0.208 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_+_139175385 0.207 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr2_+_24807345 0.206 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr1_+_95558072 0.201 NM_001199679
TMEM56
transmembrane protein 56
chr1_+_205538111 0.201 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr22_-_44893903 0.201 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr15_-_75743776 0.200 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr5_+_149109814 0.198 NM_001172698
NM_133263
PPARGC1B

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

chr2_-_101034049 0.197 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr3_-_13114547 0.196 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr16_-_87525317 0.195 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr15_-_75744029 0.194 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr10_-_21186530 0.183 NM_006393
NEBL
nebulette
chr11_-_75062650 0.183 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr17_-_73775822 0.182 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr3_+_23986735 0.179 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr15_-_75748123 0.178 NM_001145357
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr10_+_69644341 0.177 NM_012238
SIRT1
sirtuin 1
chr9_-_117267710 0.173 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr14_-_25519076 0.172 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_+_37617688 0.170 NM_015083
NM_016507
CDK12

cyclin-dependent kinase 12

chr20_+_33292117 0.170 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_+_18164423 0.170 NM_148886
SMCR7
Smith-Magenis syndrome chromosome region, candidate 7
chrX_+_9432980 0.170 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr20_-_4982133 0.168 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr17_+_18163836 0.167 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chr4_-_2263706 0.167 NM_006454
MXD4
MAX dimerization protein 4
chr17_-_43568124 0.166 NM_014798
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr22_-_50746000 0.165 NM_012401
PLXNB2
plexin B2
chr9_+_115513050 0.164 NM_001012994
SNX30
sorting nexin family member 30
chr11_+_66234293 0.163 NM_001098510
NM_001243136
NM_145065
PELI3


pellino homolog 3 (Drosophila)


chr9_-_117265452 0.162 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr10_-_12085022 0.162 NM_080599
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr10_-_12084772 0.161 NM_015542
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr10_-_21463019 0.159 NM_001173484
NM_213569
NEBL

nebulette

chr2_-_97535669 0.157 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr4_-_185570575 0.156 NM_004346
NM_032991
CASP3

caspase 3, apoptosis-related cysteine peptidase

chrX_-_53254603 0.155 NM_001146702
NM_004187
KDM5C

lysine (K)-specific demethylase 5C

chr17_+_74868728 0.155 NM_198955
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr1_+_114496498 0.155 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr6_-_100911550 0.153 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr17_-_58603492 0.152 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr15_+_57511616 0.151 NM_207040
TCF12
transcription factor 12
chr15_+_57210823 0.151 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr2_+_85581840 0.150 NM_001135021
NM_001135022
NM_001135023
NM_032213
ELMOD3



ELMO/CED-12 domain containing 3



chr10_+_18948276 0.149 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr1_+_114493766 0.148 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr9_-_111882209 0.148 NM_032012
C9orf5
chromosome 9 open reading frame 5
chr11_+_11862955 0.147 NM_017944
USP47
ubiquitin specific peptidase 47
chr4_+_159131400 0.146 NM_018342
TMEM144
transmembrane protein 144
chr3_-_142166782 0.143 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr9_-_131534186 0.142 NM_006336
ZER1
zer-1 homolog (C. elegans)
chr18_+_46065367 0.141 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr19_+_47421932 0.140 NM_004491
ARHGAP35
Rho GTPase activating protein 35
chr17_+_7743233 0.139 NM_001080424
KDM6B
lysine (K)-specific demethylase 6B
chr12_-_30830143 0.138 NM_001190995
IPO8
importin 8
chr9_-_36401149 0.137 NM_194330
RNF38
ring finger protein 38
chr7_-_131241321 0.137 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr2_+_14772809 0.135 NM_145175
FAM84A
family with sequence similarity 84, member A
chr3_-_33481877 0.134 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr17_+_36861857 0.134 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr17_-_3749455 0.133 NM_001114118
NM_018553
C17orf85

chromosome 17 open reading frame 85

chr8_-_52811707 0.133 NM_052937
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr11_-_70507911 0.132 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr19_-_11670003 0.132 NM_032377
ELOF1
elongation factor 1 homolog (S. cerevisiae)
chr14_-_75179739 0.130 NM_001039479
KIAA0317
KIAA0317
chr1_-_41131323 0.130 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr15_+_49170264 0.129 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr3_-_49823626 0.128 NM_001242829
IP6K1
inositol hexakisphosphate kinase 1
chr1_+_95582827 0.127 NM_152487
TMEM56
transmembrane protein 56
chr15_-_75199461 0.127 NM_020447
C15orf17
chromosome 15 open reading frame 17
chr1_+_162351519 0.127 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr6_+_4021500 0.126 NM_003913
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr4_-_78740508 0.125 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr3_-_33481862 0.124 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr2_+_217498082 0.122 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr16_+_71560022 0.121 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr8_-_116681103 0.120 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr5_+_140044383 0.120 NM_017706
WDR55
WD repeat domain 55
chr7_+_8008416 0.119 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr18_-_57026465 0.118 NM_005570
LMAN1
lectin, mannose-binding, 1
chr9_-_36400212 0.118 NM_022781
NM_194329
RNF38

ring finger protein 38

chr6_-_31628509 0.118 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr10_+_129845806 0.117 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr22_+_41697452 0.117 NM_017590
ZC3H7B
zinc finger CCCH-type containing 7B
chr11_-_67980699 0.117 NM_016028
NM_017635
SUV420H1

suppressor of variegation 4-20 homolog 1 (Drosophila)

chr20_+_43991739 0.116 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 readthrough
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr10_+_181410 0.116 NM_001202464
ZMYND11
zinc finger, MYND-type containing 11
chr19_+_45909466 0.115 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr20_+_47538211 0.114 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr17_-_6459746 0.114 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr20_+_32150139 0.111 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr17_+_74864427 0.111 NM_001199172
NM_144677
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr9_-_130679210 0.110 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr13_+_77566043 0.109 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr10_-_65028825 0.108 NM_004241
JMJD1C
jumonji domain containing 1C
chrX_-_102531673 0.108 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr9_-_36400817 0.108 NM_194328
NM_194332
RNF38

ring finger protein 38

chr7_+_90338711 0.107 NM_012395
CDK14
cyclin-dependent kinase 14
chr3_+_51705221 0.106 NM_001129884
NM_001243727
NM_015926
NM_001243725
NM_001243726
TEX264




testis expressed 264




chr1_+_210406194 0.106 NM_019605
SERTAD4
SERTA domain containing 4
chr3_+_42544094 0.105 NM_001251883
NM_001251884
NM_001251885
NM_004624
VIPR1



vasoactive intestinal peptide receptor 1



chr1_+_36273786 0.105 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr17_+_72983723 0.104 NM_014603
CDR2L
cerebellar degeneration-related protein 2-like
chr16_+_50186809 0.104 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr14_+_60712469 0.104 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr5_-_56247915 0.102 NM_152622
MIER3
mesoderm induction early response 1, family member 3
chr2_+_28615771 0.101 NM_005253
FOSL2
FOS-like antigen 2
chr10_-_73533196 0.101 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr1_-_109935869 0.100 NM_001205228
SORT1
sortilin 1
chr9_-_33264458 0.100 NM_001172415
NM_004323
BAG1

BCL2-associated athanogene

chr20_-_3996035 0.100 NM_007219
NM_001134337
NM_001134338
RNF24


ring finger protein 24


chr20_-_4990913 0.100 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chrX_-_25034064 0.099 NM_139058
ARX
aristaless related homeobox
chr17_+_4402128 0.097 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr15_+_44719578 0.097 NM_016396
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_+_129007942 0.097 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chrX_+_152599544 0.096 NM_001080485
ZNF275
zinc finger protein 275
chr5_+_167718485 0.096 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr7_+_128864740 0.095 NM_001130720
NM_015328
AHCYL2

adenosylhomocysteinase-like 2

chr11_-_128894008 0.095 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr15_+_64791618 0.094 NM_015042
ZNF609
zinc finger protein 609
chr5_-_90679115 0.093 NM_020801
ARRDC3
arrestin domain containing 3
chr17_-_9940004 0.093 NM_201432
GAS7
growth arrest-specific 7
chr19_+_51815095 0.092 NM_001101372
IGLON5
IgLON family member 5
chr19_+_7968764 0.092 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr16_-_57318574 0.091 NM_015993
PLLP
plasmolipin
chr3_+_49449638 0.091 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr3_-_49823972 0.091 NM_001006115
NM_153273
IP6K1

inositol hexakisphosphate kinase 1

chr20_+_816710 0.091 NM_207121
FAM110A
family with sequence similarity 110, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
6.47 1.29e-05 GO:0006402 mRNA catabolic process
6.04 2.92e-04 GO:0000956 nuclear-transcribed mRNA catabolic process
5.02 4.31e-04 GO:0006401 RNA catabolic process
8.64 1.72e-02 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
1.51 2.56e-02 GO:0010468 regulation of gene expression
2.17 4.38e-02 GO:0010629 negative regulation of gene expression

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.87 1.66e-03 GO:0005802 trans-Golgi network
1.30 5.19e-03 GO:0005634 nucleus
2.13 1.02e-02 GO:0044431 Golgi apparatus part
1.13 1.49e-02 GO:0005622 intracellular
2.31 2.58e-02 GO:0045202 synapse
1.13 3.02e-02 GO:0044424 intracellular part
7.16 3.82e-02 GO:0000932 cytoplasmic mRNA processing body
3.11 4.39e-02 GO:0030136 clathrin-coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.70 4.77e-03 GO:0003714 transcription corepressor activity
1.24 8.24e-03 GO:0005515 protein binding