Motif ID: GFI1.p2

Z-value: 1.864


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1chr1_-_92952429-0.222.5e-01Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_14247267 13.211 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr19_-_14247400 11.976 NM_018154
 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr14_-_55658205 6.829 NM_001146015
NM_014750
 DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr22_+_19467413 6.732 NM_001178010
NM_001178011
NM_003504
 CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr8_+_25316512 6.724 NM_152562
 CDCA2
cell division cycle associated 2
chr1_-_68962679 6.486 DEPDC1
DEP domain containing 1
chr22_+_19467467 6.224 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr17_+_57232859 6.006 NM_018304
 PRR11
proline rich 11
chr17_-_38574042 5.664 NM_001067
 TOP2A
topoisomerase (DNA) II alpha 170kDa
chr17_-_76183074 5.308 NM_003258
 TK1
thymidine kinase 1, soluble
chr1_-_68962726 5.041 NM_001114120
NM_017779
 DEPDC1

DEP domain containing 1

chr16_+_23690190 4.750 PLK1
polo-like kinase 1
chr3_+_172468469 4.475 ECT2
epithelial cell transforming sequence 2 oncogene
chr16_+_23690160 4.471 PLK1
polo-like kinase 1
chr12_-_120315074 4.462 NM_001206999
NM_007174
 CIT

citron (rho-interacting, serine/threonine kinase 21)

chr16_+_23690212 4.459 PLK1
polo-like kinase 1
chr16_+_23690191 4.421 NM_005030
 PLK1
polo-like kinase 1
chr20_-_54967221 4.252 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
 AURKA





aurora kinase A





chr16_+_23690234 4.200 PLK1
polo-like kinase 1
chr14_+_54863672 4.054 NM_001130851
NM_005192
 CDKN3

cyclin-dependent kinase inhibitor 3


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 71 entries
enrichment   p-value GO term description
5.39 2.89e-02 GO:0035336 long-chain fatty-acyl-CoA metabolic process
5.39 2.89e-02 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
3.47 3.09e-02 GO:0000819 sister chromatid segregation
2.88 1.79e-04 GO:0065004 protein-DNA complex assembly
2.82 1.90e-04 GO:0071824 protein-DNA complex subunit organization
2.70 3.26e-02 GO:0000236 mitotic prometaphase
2.65 1.78e-02 GO:0006334 nucleosome assembly
2.62 1.45e-02 GO:0031497 chromatin assembly
2.59 1.18e-02 GO:0034728 nucleosome organization
2.57 1.43e-02 GO:0007059 chromosome segregation
2.48 3.95e-03 GO:0006323 DNA packaging
2.46 3.60e-09 GO:0000087 M phase of mitotic cell cycle
2.39 7.29e-08 GO:0000280 nuclear division
2.39 7.29e-08 GO:0007067 mitosis
2.39 1.98e-05 GO:0000075 cell cycle checkpoint
2.35 1.12e-07 GO:0048285 organelle fission
2.35 2.58e-05 GO:0071156 regulation of cell cycle arrest
2.34 5.51e-03 GO:0071103 DNA conformation change
2.34 1.56e-02 GO:0006310 DNA recombination
2.32 2.52e-11 GO:0000279 M phase

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
4.36 3.54e-02 GO:0000795 synaptonemal complex
3.39 4.43e-02 GO:0005758 mitochondrial intermembrane space
3.31 3.09e-02 GO:0031970 organelle envelope lumen
3.14 5.25e-03 GO:0000794 condensed nuclear chromosome
2.93 1.46e-02 GO:0030496 midbody
2.78 1.95e-02 GO:0000922 spindle pole
2.49 1.70e-04 GO:0000793 condensed chromosome
2.43 4.03e-02 GO:0000776 kinetochore
2.39 2.73e-05 GO:0005819 spindle
2.22 6.75e-03 GO:0000775 chromosome, centromeric region
2.15 2.99e-03 GO:0044454 nuclear chromosome part
2.04 2.48e-03 GO:0000228 nuclear chromosome
2.00 1.44e-09 GO:0005694 chromosome
1.99 1.11e-07 GO:0044427 chromosomal part
1.99 2.14e-03 GO:0000785 chromatin
1.52 8.29e-03 GO:0015630 microtubule cytoskeleton
1.46 4.01e-05 GO:0005654 nucleoplasm
1.43 7.76e-08 GO:0005829 cytosol
1.40 1.06e-05 GO:0031981 nuclear lumen
1.39 2.16e-07 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.61 4.87e-02 GO:0042393 histone binding
1.54 2.35e-03 GO:0019899 enzyme binding
1.31 3.33e-02 GO:0005524 ATP binding
1.24 4.52e-02 GO:0000166 nucleotide binding
1.22 4.36e-12 GO:0005515 protein binding
1.10 9.34e-08 GO:0005488 binding