Motif ID: GGACGGA

Z-value: 0.162


Mature miRNA associated with seed GGACGGA:

NamemiRBase Accession
hsa-miR-184 MIMAT0000454



Activity profile for motif GGACGGA.

activity profile for motif GGACGGA


Sorted Z-values histogram for motif GGACGGA

Sorted Z-values for motif GGACGGA



Network of associatons between targets according to the STRING database.



First level regulatory network of GGACGGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_102504661 0.095 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr12_-_63328663 0.070 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr11_+_46299161 0.062 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr4_+_41362750 0.053 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr7_+_73442426 0.050 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr4_+_41614911 0.050 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_-_19229016 0.047 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr7_+_90893735 0.043 NM_003505
FZD1
frizzled family receptor 1
chr12_-_125052009 0.042 NM_001077261
NM_001206654
NM_006312
NCOR2


nuclear receptor corepressor 2


chr15_+_31619043 0.040 NM_015995
KLF13
Kruppel-like factor 13
chr3_-_58563490 0.038 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr2_-_86333277 0.035 NM_015425
POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr8_-_143851223 0.034 NM_177458
LYNX1
Ly6/neurotoxin 1
chr17_+_34058678 0.034 NM_033315
RASL10B
RAS-like, family 10, member B
chr17_+_14204326 0.031 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr3_+_49506079 0.031 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr5_+_176560627 0.031 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr5_+_176560056 0.030 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr15_-_79298001 0.030 NM_153815
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr3_+_49507470 0.028 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr19_-_42746723 0.027 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chrX_-_53713657 0.026 NM_031407
HUWE1
HECT, UBA and WWE domain containing 1
chr19_+_56124958 0.026 NM_001195605
ZNF865
zinc finger protein 865
chr1_+_224301790 0.026 NM_001136115
NM_015176
FBXO28

F-box protein 28

chr3_-_147122070 0.026 NM_001168378
ZIC4
Zic family member 4
chr3_-_147124595 0.025 NM_001243256
NM_032153
ZIC4

Zic family member 4

chr12_+_54393876 0.024 NM_006897
HOXC9
homeobox C9
chr16_-_70323407 0.024 NM_001605
AARS
alanyl-tRNA synthetase
chr15_-_83621350 0.024 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr20_-_31071187 0.023 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr20_-_43438881 0.022 NM_001205317
NM_182970
RIMS4

regulating synaptic membrane exocytosis 4

chr11_-_64546201 0.022 NM_004630
NM_201995
NM_201997
NM_201998
SF1



splicing factor 1



chr6_+_160769365 0.022 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr22_-_45405429 0.021 NM_138415
PHF21B
PHD finger protein 21B
chr1_+_53527723 0.020 NM_001199080
NM_001199082
NM_153703
PODN


podocan


chr1_+_53527822 0.020 NM_001199081
PODN
podocan
chr22_-_45405780 0.019 NM_001135862
PHF21B
PHD finger protein 21B
chr1_-_44497132 0.019 NM_001024845
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_+_189349215 0.019 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr22_+_21771661 0.018 NM_015094
HIC2
hypermethylated in cancer 2
chr11_-_64545933 0.018 NM_001178030
SF1
splicing factor 1
chr3_+_189507448 0.017 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr3_-_147123306 0.017 NM_001168379
ZIC4
Zic family member 4
chr1_+_955468 0.016 NM_198576
AGRN
agrin
chr20_+_57414794 0.016 NM_016592
GNAS
GNAS complex locus
chr22_-_45404785 0.016 NM_001242450
PHF21B
PHD finger protein 21B
chr19_+_54960064 0.016 NM_052925
LENG8
leukocyte receptor cluster (LRC) member 8
chr22_+_22020272 0.016 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr14_+_70078309 0.016 NM_014734
KIAA0247
KIAA0247
chr1_-_19217384 0.015 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr5_-_73937248 0.015 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr9_+_131644780 0.015 NM_001127244
LRRC8A
leucine rich repeat containing 8 family, member A
chr19_-_11591439 0.015 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr1_-_21978287 0.015 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr4_-_174451356 0.014 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr19_-_4400470 0.014 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr22_-_39636906 0.014 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide
chr6_+_117996616 0.014 NM_138459
NUS1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
chr1_-_44482996 0.014 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr19_+_11071583 0.014 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr19_+_11094799 0.013 NM_001128845
NM_001128846
NM_001128847
NM_001128848
SMARCA4



SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4



chr11_+_66036027 0.013 NM_030981
RAB1B
RAB1B, member RAS oncogene family
chr19_+_11071792 0.013 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr12_-_108991893 0.013 NM_181724
TMEM119
transmembrane protein 119
chr20_-_3687774 0.013 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr21_-_36260972 0.013 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1

chr1_+_22778343 0.013 NM_001083621
NM_014870
ZBTB40

zinc finger and BTB domain containing 40

chr19_-_45908288 0.012 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr11_-_64545231 0.012 NM_001178031
SF1
splicing factor 1
chr15_-_34394016 0.012 NM_020154
C15orf24
chromosome 15 open reading frame 24
chr16_+_66968319 0.011 NM_003869
NM_198061
CES2

carboxylesterase 2

chr9_+_134305476 0.011 NM_013318
PRRC2B
proline-rich coiled-coil 2B
chr15_-_99057610 0.011 NM_182562
FAM169B
family with sequence similarity 169, member B
chr19_-_51220194 0.011 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr21_-_36421586 0.011 NM_001754
RUNX1
runt-related transcription factor 1
chr9_+_140033588 0.011 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr22_-_32146119 0.010 NM_173566
PRR14L
proline rich 14-like
chr11_-_797955 0.010 NM_001191060
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr9_+_131644368 0.010 NM_001127245
NM_019594
LRRC8A

leucine rich repeat containing 8 family, member A

chr19_-_45909566 0.010 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_-_21995793 0.010 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr9_+_132388404 0.009 NM_014064
METTL11A
methyltransferase like 11A
chr22_+_40573879 0.009 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr6_+_27782793 0.009 NM_003521
HIST1H2BM
histone cluster 1, H2bm
chr8_+_55047780 0.008 NM_014175
MRPL15
mitochondrial ribosomal protein L15
chr2_+_131513007 0.008 NM_152698
NM_001105193
FAM123C

family with sequence similarity 123C

chr20_-_3766905 0.008 NM_001810
CENPB
centromere protein B, 80kDa
chr11_+_117049838 0.008 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr17_+_2699731 0.008 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr12_+_121124922 0.008 NM_014730
MLEC
malectin
chr19_+_18794391 0.008 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr10_+_102295572 0.008 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_+_244816349 0.007 NM_016076
PPPDE1
PPPDE peptidase domain containing 1
chr11_+_71935824 0.007 NM_001567
INPPL1
inositol polyphosphate phosphatase-like 1
chr7_+_150783771 0.006 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chr10_-_101190201 0.006 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr17_-_48072566 0.005 NM_005220
DLX3
distal-less homeobox 3
chr10_+_80828776 0.005 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr1_-_179112178 0.005 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr6_-_31628509 0.005 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr5_-_171433876 0.005 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr11_-_796175 0.005 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr22_+_40440664 0.004 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr8_-_145550536 0.004 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr22_+_20119354 0.004 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr2_+_131513782 0.004 NM_001105194
NM_001105195
FAM123C

family with sequence similarity 123C

chr19_+_10982244 0.004 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1
chr1_-_179198814 0.003 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr18_-_67872897 0.003 NM_173630
RTTN
rotatin
chr1_+_110163275 0.003 NM_004037
AMPD2
adenosine monophosphate deaminase 2
chr7_-_44365019 0.003 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr11_-_798196 0.003 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr19_+_10764896 0.003 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr4_-_1242882 0.002 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1

chr6_+_108882068 0.002 NM_001455
FOXO3
forkhead box O3
chr9_+_34958171 0.002 NM_015297
KIAA1045
KIAA1045
chr6_+_108881010 0.002 NM_201559
FOXO3
forkhead box O3
chr5_-_172756505 0.001 NM_003714
STC2
stanniocalcin 2
chr17_+_17584772 0.001 NM_030665
RAI1
retinoic acid induced 1
chr1_+_110168048 0.001 NM_203404
AMPD2
adenosine monophosphate deaminase 2
chr2_-_157189040 0.001 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_110162427 0.000 NM_139156
AMPD2
adenosine monophosphate deaminase 2
chr1_+_110453232 0.000 NM_000757
NM_172210
NM_172212
CSF1


colony stimulating factor 1 (macrophage)


chr16_+_1203240 0.000 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.79 2.36e-04 GO:0010628 positive regulation of gene expression
4.85 5.26e-04 GO:0045893 positive regulation of transcription, DNA-dependent
4.34 8.14e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
4.27 1.01e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.52 1.21e-03 GO:0051254 positive regulation of RNA metabolic process
4.14 1.47e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
3.37 2.42e-03 GO:0010604 positive regulation of macromolecule metabolic process
2.36 2.43e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.86 3.44e-03 GO:0031328 positive regulation of cellular biosynthetic process
3.28 3.60e-03 GO:0031325 positive regulation of cellular metabolic process
3.80 4.22e-03 GO:0009891 positive regulation of biosynthetic process
2.29 4.43e-03 GO:0051171 regulation of nitrogen compound metabolic process
3.54 4.89e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.97 6.85e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.10 7.87e-03 GO:0009893 positive regulation of metabolic process
2.34 1.11e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.28 1.76e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.21 2.95e-02 GO:0010468 regulation of gene expression

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.68 4.06e-03 GO:0016563 transcription activator activity