Motif ID: GLI1..3.p2

Z-value: 2.323


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI1chr12_+_578539170.761.3e-06Click!
GLI3chr7_-_422766170.641.3e-04Click!
GLI2chr2_+_1215548660.561.2e-03Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_39873276 11.110 NM_003246
 THBS1
thrombospondin 1
chr19_-_41859519 8.536 TGFB1
transforming growth factor, beta 1
chr19_-_51472003 8.371 NM_001012964
NM_001012965
 KLK6

kallikrein-related peptidase 6

chr17_-_34122547 7.405 NM_001032278
NM_024302
 MMP28

matrix metallopeptidase 28

chr12_-_57634474 7.014 NM_020142
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_65991357 6.826 NM_001198687
NM_001198688
NM_001198689
 LEPR


leptin receptor


chr19_-_41859332 6.665 TGFB1
transforming growth factor, beta 1
chr20_+_62328002 5.945 NM_003823
 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_+_152881022 5.897 NM_005547
 IVL
involucrin
chr5_-_157002739 5.891 NM_033274
 ADAM19
ADAM metallopeptidase domain 19
chr2_-_26205327 5.886 KIF3C
kinesin family member 3C
chr1_+_150521786 5.813 NM_019032
NM_025008
 ADAMTSL4

ADAMTS-like 4

chr20_+_62328068 5.802 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr7_+_100770378 5.675 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_+_32042085 5.668 NM_001204414
NM_022164
 TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_-_152386727 5.625 NM_016190
 CRNN
cornulin
chr10_-_90712510 5.606 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_-_52845862 5.488 NM_005555
 KRT6B
keratin 6B
chr1_+_32042122 5.460 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_32042125 5.259 TINAGL1
tubulointerstitial nephritis antigen-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 54 entries
enrichment   p-value GO term description
2.37 4.49e-05 GO:0034330 cell junction organization
2.28 1.27e-03 GO:0034329 cell junction assembly
2.11 2.73e-03 GO:0051272 positive regulation of cellular component movement
2.05 1.85e-02 GO:0030335 positive regulation of cell migration
2.05 1.85e-02 GO:2000147 positive regulation of cell motility
2.03 1.82e-02 GO:0040017 positive regulation of locomotion
1.82 2.33e-03 GO:0051270 regulation of cellular component movement
1.80 4.34e-03 GO:0040012 regulation of locomotion
1.78 2.35e-02 GO:0030334 regulation of cell migration
1.76 3.51e-02 GO:2000145 regulation of cell motility
1.72 1.95e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.71 4.69e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.67 3.57e-02 GO:0007411 axon guidance
1.65 4.70e-05 GO:0042060 wound healing
1.62 1.42e-02 GO:0007409 axonogenesis
1.60 1.82e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.59 7.60e-03 GO:0007596 blood coagulation
1.59 7.60e-03 GO:0050817 coagulation
1.59 2.05e-02 GO:0048812 neuron projection morphogenesis
1.58 1.03e-02 GO:0007599 hemostasis

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.33 4.93e-03 GO:0001726 ruffle
2.25 5.55e-03 GO:0005925 focal adhesion
2.21 5.78e-03 GO:0005924 cell-substrate adherens junction
2.13 1.32e-02 GO:0030055 cell-substrate junction
2.04 2.30e-03 GO:0005912 adherens junction
1.95 1.97e-03 GO:0031252 cell leading edge
1.89 1.42e-02 GO:0070161 anchoring junction
1.61 1.86e-05 GO:0030054 cell junction
1.40 2.46e-04 GO:0000267 cell fraction
1.39 1.19e-02 GO:0005624 membrane fraction
1.37 1.77e-02 GO:0005626 insoluble fraction
1.24 2.74e-03 GO:0044459 plasma membrane part
1.23 1.31e-02 GO:0005829 cytosol
1.11 1.87e-04 GO:0005737 cytoplasm
1.11 3.07e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.19 4.94e-13 GO:0005515 protein binding
1.06 1.59e-02 GO:0005488 binding