Motif ID: GTF2A1,2.p2

Z-value: 1.586


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A2chr15_-_59949536-0.451.3e-02Click!
GTF2A1chr14_-_816872650.038.9e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153013593 6.080 NM_006945
 SPRR2D
small proline-rich protein 2D
chr15_-_74495093 5.642 NM_001199042
NM_022369
 STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr2_-_31440378 5.582 NM_001145122
 CAPN14
calpain 14
chr12_+_53491417 5.158 NM_002178
 IGFBP6
insulin-like growth factor binding protein 6
chr15_-_74495528 5.073 NM_001142618
 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr1_-_153044083 5.011 NM_001017418
 SPRR2B
small proline-rich protein 2B
chr1_-_153067000 4.477 NM_001024209
 SPRR2E
small proline-rich protein 2E
chr12_+_53491448 4.422 IGFBP6
insulin-like growth factor binding protein 6
chr7_-_41742666 4.291 NM_002192
 INHBA
inhibin, beta A
chr7_+_100770378 3.964 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr10_-_5541401 3.790 NM_017422
 CALML5
calmodulin-like 5
chr22_+_30792929 3.672 NM_001204204
NM_012429
NM_033382
 SEC14L2


SEC14-like 2 (S. cerevisiae)


chr9_+_131191206 3.415 CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_153085963 3.369 NM_001014450
 SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr19_-_43032525 3.206 NM_001024912
NM_001184813
NM_001184815
NM_001184816
NM_001205344
NM_001712
 CEACAM1





carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)





chr8_-_23177481 3.132 LOXL2
lysyl oxidase-like 2
chr21_-_28217692 3.099 NM_006988
 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_+_130318457 3.096 NM_139055
 ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr9_-_136242925 3.088 SURF4
surfeit 4
chr19_+_48828627 3.022 NM_001425
 EMP3
epithelial membrane protein 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.71 4.20e-02 GO:0002576 platelet degranulation
2.12 4.61e-05 GO:0030029 actin filament-based process
2.08 1.02e-03 GO:0030036 actin cytoskeleton organization
1.81 1.10e-04 GO:0007596 blood coagulation
1.81 1.10e-04 GO:0050817 coagulation
1.80 1.50e-04 GO:0007599 hemostasis
1.76 5.01e-05 GO:0042060 wound healing
1.75 1.33e-04 GO:0050878 regulation of body fluid levels
1.67 1.33e-06 GO:0009611 response to wounding
1.67 1.14e-02 GO:0007010 cytoskeleton organization
1.48 2.73e-03 GO:0007154 cell communication
1.47 2.69e-04 GO:0002376 immune system process
1.47 4.58e-02 GO:0006952 defense response
1.33 1.11e-04 GO:0006950 response to stress
1.33 7.18e-04 GO:0065008 regulation of biological quality
1.27 1.72e-03 GO:0048731 system development
1.26 2.41e-05 GO:0023052 signaling
1.26 3.91e-04 GO:0048856 anatomical structure development
1.23 4.46e-03 GO:0007275 multicellular organismal development
1.22 1.74e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
6.46 3.34e-02 GO:0005952 cAMP-dependent protein kinase complex
3.05 1.64e-05 GO:0001726 ruffle
2.88 6.41e-03 GO:0031256 leading edge membrane
2.27 1.05e-04 GO:0031252 cell leading edge
1.71 2.38e-02 GO:0005578 proteinaceous extracellular matrix
1.66 1.61e-02 GO:0031012 extracellular matrix
1.56 2.33e-06 GO:0044421 extracellular region part
1.50 2.24e-03 GO:0005615 extracellular space
1.45 2.29e-09 GO:0005576 extracellular region
1.43 9.87e-03 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.70 4.35e-02 GO:0003779 actin binding
1.62 2.98e-03 GO:0008092 cytoskeletal protein binding
1.13 2.91e-04 GO:0005515 protein binding
1.06 1.69e-02 GO:0005488 binding