Motif ID: GUAAACA

Z-value: 1.332


Mature miRNA associated with seed GUAAACA:

NamemiRBase Accession
hsa-miR-30a MIMAT0000087
hsa-miR-30b MIMAT0000420
hsa-miR-30c MIMAT0000244
hsa-miR-30d MIMAT0000245
hsa-miR-30e MIMAT0000692



Activity profile for motif GUAAACA.

activity profile for motif GUAAACA


Sorted Z-values histogram for motif GUAAACA

Sorted Z-values for motif GUAAACA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAAACA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_21494663 1.904 NM_002509
 NKX2-2
NK2 homeobox 2
chr4_-_139163222 1.754 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr8_+_26371461 1.597 NM_001197293
 DPYSL2
dihydropyrimidinase-like 2
chr6_+_86159301 1.318 NM_001204813
NM_002526
 NT5E

5'-nucleotidase, ecto (CD73)

chr8_+_26435339 1.299 NM_001386
 DPYSL2
dihydropyrimidinase-like 2
chr8_+_92082423 1.127 NM_016023
 OTUD6B
OTU domain containing 6B
chr5_+_172068188 1.093 NM_001142651
 NEURL1B
neuralized homolog 1B (Drosophila)
chr12_-_77459198 1.074 NM_203394
 E2F7
E2F transcription factor 7
chr7_+_18126543 1.020 NM_001204144
 HDAC9
histone deacetylase 9
chr7_+_18548899 0.999 NM_001204147
NM_001204148
 HDAC9

histone deacetylase 9

chr1_+_91966365 0.946 NM_001134419
NM_003503
 CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr1_+_91966653 0.942 NM_001134420
 CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr13_-_61989654 0.940 NM_022843
 PCDH20
protocadherin 20
chr9_-_27573444 0.933 NM_018325
 C9orf72
chromosome 9 open reading frame 72
chr16_+_2039945 0.915 NM_004209
 SYNGR3
synaptogyrin 3
chr7_+_87505543 0.905 NM_006716
 DBF4
DBF4 homolog (S. cerevisiae)
chr7_+_94285620 0.893 NM_001040152
NM_001184961
NM_001184962
NM_015068
 PEG10



paternally expressed 10



chr7_+_94285676 0.856 NM_001172437
NM_001172438
 PEG10

paternally expressed 10

chr5_-_159739482 0.815 NM_024565
 CCNJL
cyclin J-like
chr10_+_17270257 0.800 NM_003380
 VIM
vimentin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.18 4.56e-02 GO:0016197 endosome transport
2.17 1.09e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.94 5.94e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.93 1.00e-02 GO:0010629 negative regulation of gene expression
1.92 4.08e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.89 1.07e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.84 1.62e-02 GO:0009890 negative regulation of biosynthetic process
1.84 1.77e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.82 4.29e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.81 1.23e-02 GO:0016192 vesicle-mediated transport
1.68 4.66e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.50 7.94e-03 GO:0006464 protein modification process
1.48 9.12e-03 GO:0043412 macromolecule modification
1.28 1.53e-02 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.26 2.85e-04 GO:0005634 nucleus
1.16 1.27e-08 GO:0005622 intracellular
1.16 7.33e-08 GO:0044424 intracellular part
1.16 5.47e-03 GO:0005737 cytoplasm
1.15 6.55e-04 GO:0043229 intracellular organelle
1.15 8.58e-04 GO:0043226 organelle
1.14 3.09e-02 GO:0043231 intracellular membrane-bounded organelle
1.14 3.50e-02 GO:0043227 membrane-bounded organelle
1.06 4.14e-03 GO:0044464 cell part
1.06 4.23e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.49 4.31e-04 GO:0008270 zinc ion binding
1.43 1.37e-03 GO:0046914 transition metal ion binding