Motif ID: GUAACAG

Z-value: 0.521


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_139726173 1.573 NM_001945
 HBEGF
heparin-binding EGF-like growth factor
chr12_-_76425375 1.336 NM_007350
 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_-_25102281 1.104 NM_001178091
NM_001178092
NM_005504
 BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr12_-_25055966 1.048 NM_001178093
 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_25055228 1.040 NM_001178094
 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr14_+_85996454 0.831 NM_013231
 FLRT2
fibronectin leucine rich transmembrane protein 2
chr18_+_56530060 0.662 NM_018181
 ZNF532
zinc finger protein 532
chr9_-_124984018 0.659 NM_001242335
 LHX6
LIM homeobox 6
chr5_-_59995938 0.648 NM_001145208
NM_018369
 DEPDC1B

DEP domain containing 1B

chr11_-_115375065 0.618 NM_001098517
NM_014333
 CADM1

cell adhesion molecule 1

chr9_-_124990706 0.611 NM_001242333
 LHX6
LIM homeobox 6
chr9_-_124990949 0.540 NM_014368
NM_199160
 LHX6

LIM homeobox 6

chr21_-_16437125 0.538 NM_003489
 NRIP1
nuclear receptor interacting protein 1
chr7_-_94285477 0.493 NM_001099400
NM_001099401
NM_003919
 SGCE


sarcoglycan, epsilon


chr16_-_87903028 0.486 NM_003486
 SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chrX_+_38420690 0.479 NM_004615
 TSPAN7
tetraspanin 7
chr11_+_69924407 0.466 NM_018043
 ANO1
anoctamin 1, calcium activated chloride channel
chr12_+_26348268 0.442 NM_001135823
 SSPN
sarcospan (Kras oncogene-associated gene)
chr7_-_98741681 0.434 NM_001199847
NM_020429
NM_181349
 SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr8_-_131455833 0.433 NM_001247996
NM_018482
 ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
5.27 1.36e-03 GO:0001701 in utero embryonic development
3.81 4.44e-02 GO:0001944 vasculature development
3.52 2.91e-02 GO:0044419 interspecies interaction between organisms
3.43 3.94e-02 GO:0009792 embryo development ending in birth or egg hatching
3.21 9.98e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.10 4.25e-02 GO:0072358 cardiovascular system development
3.10 4.25e-02 GO:0072359 circulatory system development
3.07 1.24e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.07 2.15e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
3.02 2.16e-02 GO:0051253 negative regulation of RNA metabolic process
3.01 1.79e-03 GO:0009890 negative regulation of biosynthetic process
2.99 9.15e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.95 1.11e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.77 1.81e-02 GO:0009790 embryo development
2.52 1.58e-02 GO:0031324 negative regulation of cellular metabolic process
2.50 3.96e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.49 1.92e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.41 2.29e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.40 2.63e-02 GO:0009892 negative regulation of metabolic process
2.04 7.10e-04 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
10.72 3.32e-03 GO:0017053 transcriptional repressor complex
10.07 2.29e-02 GO:0000118 histone deacetylase complex
1.48 9.20e-04 GO:0005634 nucleus
1.24 2.86e-04 GO:0044424 intracellular part
1.23 2.53e-02 GO:0043229 intracellular organelle
1.23 2.82e-02 GO:0043226 organelle
1.22 6.46e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
78.55 3.70e-02 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity
2.20 3.20e-02 GO:0001071 nucleic acid binding transcription factor activity
2.20 3.20e-02 GO:0003700 sequence-specific DNA binding transcription factor activity