Motif ID: GUAACAG

Z-value: 0.521


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_139726173 1.573 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr12_-_76425375 1.336 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_-_25102281 1.104 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr12_-_25055966 1.048 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr12_-_25055228 1.040 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr14_+_85996454 0.831 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr18_+_56530060 0.662 NM_018181
ZNF532
zinc finger protein 532
chr9_-_124984018 0.659 NM_001242335
LHX6
LIM homeobox 6
chr5_-_59995938 0.648 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr11_-_115375065 0.618 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr9_-_124990706 0.611 NM_001242333
LHX6
LIM homeobox 6
chr9_-_124990949 0.540 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr21_-_16437125 0.538 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr7_-_94285477 0.493 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr16_-_87903028 0.486 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chrX_+_38420690 0.479 NM_004615
TSPAN7
tetraspanin 7
chr11_+_69924407 0.466 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr12_+_26348268 0.442 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr7_-_98741681 0.434 NM_001199847
NM_020429
NM_181349
SMURF1


SMAD specific E3 ubiquitin protein ligase 1


chr8_-_131455833 0.433 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr9_-_124989755 0.423 NM_001242334
LHX6
LIM homeobox 6
chr6_+_163835668 0.416 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr7_+_77167351 0.411 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr8_+_42752019 0.407 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr12_+_93963597 0.400 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr12_+_26348488 0.392 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr10_-_75634219 0.374 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr14_+_55034329 0.360 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr15_-_34630203 0.348 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr15_-_34629941 0.334 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr15_-_34629044 0.328 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr14_+_55221505 0.328 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr2_+_210444364 0.322 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr2_+_102314162 0.311 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr2_+_210288668 0.303 NM_001039538
MAP2
microtubule-associated protein 2
chr17_-_33390676 0.302 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr7_+_77166750 0.297 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr20_-_25604583 0.295 NM_152667
NANP
N-acetylneuraminic acid phosphatase
chr19_-_40791291 0.284 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr15_-_34610928 0.282 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr20_-_56286540 0.281 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_-_112579726 0.276 NM_152556
C7orf60
chromosome 7 open reading frame 60
chr14_-_91282760 0.271 NM_001010854
TTC7B
tetratricopeptide repeat domain 7B
chrX_-_119709618 0.267 NM_003588
CUL4B
cullin 4B
chr15_-_59981517 0.265 NM_004330
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr3_-_113465101 0.255 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_82266081 0.245 NM_012302
LPHN2
latrophilin 2
chr20_-_56284945 0.238 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr12_-_123594974 0.237 NM_020845
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr12_+_27677044 0.232 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr20_-_56285576 0.228 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr22_-_22221953 0.226 NM_002745
NM_138957
MAPK1

mitogen-activated protein kinase 1

chr2_+_238600780 0.214 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr7_-_559479 0.213 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chrX_+_38660653 0.209 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr3_+_152880024 0.208 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chr1_+_184356128 0.206 NM_030806
C1orf21
chromosome 1 open reading frame 21
chr15_+_39873276 0.205 NM_003246
THBS1
thrombospondin 1
chr3_-_71778268 0.197 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr3_-_18480203 0.193 NM_001131010
SATB1
SATB homeobox 1
chr2_-_122406994 0.191 NM_001142273
NM_001142274
NM_001207051
NM_015282
CLASP1



cytoplasmic linker associated protein 1



chr18_-_3011944 0.185 NM_014646
LPIN2
lipin 2
chr4_+_77870864 0.175 NM_018243
SEPT11
septin 11
chr18_+_43753986 0.169 NM_001008239
NM_145055
C18orf25

chromosome 18 open reading frame 25

chrX_+_38663072 0.165 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr4_-_5710293 0.163 NM_147127
EVC2
Ellis van Creveld syndrome 2
chr17_+_38474472 0.163 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr5_+_14664764 0.162 NM_138348
FAM105B
family with sequence similarity 105, member B
chr8_-_28243941 0.160 NM_018660
ZNF395
zinc finger protein 395
chr3_-_195808958 0.160 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr12_+_123868608 0.160 NM_020382
SETD8
SET domain containing (lysine methyltransferase) 8
chr3_-_195808997 0.154 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chrX_-_119694719 0.153 NM_001079872
CUL4B
cullin 4B
chr14_-_100070442 0.149 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr18_+_19321544 0.148 NM_020774
MIB1
mindbomb homolog 1 (Drosophila)
chr3_-_98620452 0.148 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr15_+_59063389 0.145 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr17_+_38465422 0.144 NM_000964
RARA
retinoic acid receptor, alpha
chr7_-_42276617 0.142 NM_000168
GLI3
GLI family zinc finger 3
chr19_+_41903693 0.140 NM_000709
NM_001164783
BCKDHA

branched chain keto acid dehydrogenase E1, alpha polypeptide

chr1_-_52456292 0.140 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr9_-_95527002 0.138 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr1_+_24645914 0.136 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr3_-_18466759 0.135 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr11_-_102962903 0.134 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr4_-_5711274 0.132 NM_001166136
EVC2
Ellis van Creveld syndrome 2
chr4_+_37246689 0.132 NM_001144990
KIAA1239
KIAA1239
chr1_+_24649529 0.132 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr12_-_54653369 0.123 NM_001127321
CBX5
chromobox homolog 5
chr4_-_153303663 0.120 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr3_+_180630054 0.117 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr3_-_71803513 0.113 NM_001134649
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr5_+_72112417 0.112 NM_002270
TNPO1
transportin 1
chr15_+_38544966 0.112 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr8_+_55370494 0.111 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr9_-_8733893 0.109 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr12_+_107349539 0.107 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr14_-_57735614 0.106 NM_006544
EXOC5
exocyst complex component 5
chr3_-_71803923 0.106 NM_173359
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr18_-_28681885 0.105 NM_004949
NM_024422
DSC2

desmocollin 2

chr1_-_221910801 0.104 NM_144728
DUSP10
dual specificity phosphatase 10
chr12_-_54653317 0.100 NM_001127322
CBX5
chromobox homolog 5
chr17_-_8534008 0.097 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr1_-_221915458 0.097 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr19_-_18632886 0.096 NM_006532
ELL
elongation factor RNA polymerase II
chr11_-_70935807 0.094 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr11_-_70507911 0.092 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_-_243418675 0.090 NM_001042404
NM_001042405
NM_014812
CEP170


centrosomal protein 170kDa


chr17_-_63052884 0.090 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr12_-_53994783 0.089 NM_001130059
ATF7
activating transcription factor 7
chr8_+_38034066 0.089 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr12_+_56915587 0.088 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_+_2985730 0.088 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr8_+_15397595 0.085 NM_006765
NM_178234
TUSC3

tumor suppressor candidate 3

chr13_-_74707913 0.085 NM_007249
KLF12
Kruppel-like factor 12
chr14_-_74226890 0.085 NM_194278
C14orf43
chromosome 14 open reading frame 43
chr3_-_71774407 0.084 NM_001134651
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr3_+_14166439 0.081 NM_024334
TMEM43
transmembrane protein 43
chr1_-_94703252 0.081 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr13_-_107187312 0.080 NM_004093
EFNB2
ephrin-B2
chr12_-_26277807 0.080 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr9_-_10612722 0.078 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr2_-_208634051 0.077 NM_003468
FZD5
frizzled family receptor 5
chrX_-_41782230 0.077 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr14_-_54955714 0.076 NM_004124
GMFB
glia maturation factor, beta
chr1_+_52608045 0.076 NM_004799
NM_007323
NM_007324
ZFYVE9


zinc finger, FYVE domain containing 9


chr6_+_20402040 0.075 NM_001949
E2F3
E2F transcription factor 3
chr18_+_55102777 0.074 NM_004852
ONECUT2
one cut homeobox 2
chr1_-_214724974 0.072 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_59436488 0.072 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr5_+_176560056 0.071 NM_172349
NSD1
nuclear receptor binding SET domain protein 1
chr9_+_72658496 0.070 NM_153267
MAMDC2
MAM domain containing 2
chr5_+_66124603 0.069 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_+_87928083 0.069 NM_005935
AFF1
AF4/FMR2 family, member 1
chr2_-_197791339 0.069 NM_024989
PGAP1
post-GPI attachment to proteins 1
chr11_+_12695851 0.069 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_-_25474948 0.068 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_30669133 0.067 NM_022344
C17orf75
chromosome 17 open reading frame 75
chr11_+_107461807 0.067 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr18_-_74207145 0.066 NM_014643
ZNF516
zinc finger protein 516
chr10_-_25012543 0.065 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr3_+_39851028 0.064 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr1_+_24645811 0.063 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr1_-_226926875 0.062 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr12_+_12869818 0.062 NM_004064
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr9_-_93405066 0.060 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr10_-_33623771 0.060 NM_001024628
NM_001024629
NM_001244972
NM_001244973
NM_003873
NRP1




neuropilin 1




chr3_+_196594708 0.060 NM_152699
SENP5
SUMO1/sentrin specific peptidase 5
chr1_+_93811476 0.059 NM_001938
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
chr9_+_108006892 0.058 NM_080546
SLC44A1
solute carrier family 44, member 1
chr3_+_9439290 0.058 NM_001080517
SETD5
SET domain containing 5
chr13_+_28712379 0.056 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr16_-_31100129 0.056 NM_001039503
PRSS53
protease, serine, 53
chr15_-_30114536 0.053 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr11_-_16497917 0.053 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr3_+_196466724 0.053 NM_002577
PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr2_+_203499819 0.051 NM_173511
FAM117B
family with sequence similarity 117, member B
chr3_-_122233781 0.050 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr9_-_74979829 0.049 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chr2_+_60983354 0.049 NM_022894
PAPOLG
poly(A) polymerase gamma
chr16_+_47495166 0.049 NM_000293
NM_001031835
PHKB

phosphorylase kinase, beta

chr10_+_116581495 0.048 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr5_-_89825292 0.048 NM_198273
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr15_+_77713229 0.047 NM_018200
HMG20A
high mobility group 20A
chr21_+_38791206 0.047 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr5_+_72143929 0.046 NM_153188
TNPO1
transportin 1
chr14_-_74253876 0.046 NM_001043318
C14orf43
chromosome 14 open reading frame 43
chr5_-_141704575 0.045 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr5_-_58882274 0.044 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_184020343 0.042 NM_024949
WWC2
WW and C2 domain containing 2
chr2_-_25564745 0.042 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chrX_+_152907892 0.041 NM_001395
DUSP9
dual specificity phosphatase 9
chr6_+_157802479 0.041 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr3_+_38495778 0.040 NM_001106
ACVR2B
activin A receptor, type IIB
chr3_-_125314367 0.040 NM_022776
OSBPL11
oxysterol binding protein-like 11
chr6_-_43027114 0.039 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr9_-_123555654 0.039 NM_012164
FBXW2
F-box and WD repeat domain containing 2
chr11_+_74660290 0.039 NM_014752
LOC653566
SPCS2
signal peptidase complex subunit 2 homolog pseudogene
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr3_+_37903643 0.039 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr6_-_62995852 0.037 NM_152688
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr1_-_202777545 0.037 NM_006618
KDM5B
lysine (K)-specific demethylase 5B
chr11_-_18655962 0.037 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr1_-_178840079 0.037 NM_004673
ANGPTL1
angiopoietin-like 1
chr5_+_176560627 0.035 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr12_-_31743822 0.035 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr12_-_24102563 0.034 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr3_-_149688638 0.034 NM_002628
NM_053024
PFN2

profilin 2

chr11_+_111473099 0.034 NM_015191
SIK2
salt-inducible kinase 2
chr8_-_54755546 0.033 NM_213620
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr7_+_138916230 0.033 NM_173569
UBN2
ubinuclein 2
chr22_-_30642683 0.033 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr18_+_3447607 0.033 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr4_-_74904329 0.032 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr10_-_88281515 0.032 NM_015045
WAPAL
wings apart-like homolog (Drosophila)
chr6_+_107811272 0.032 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr18_+_3451589 0.032 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr10_+_98592015 0.032 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr11_-_16424391 0.031 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chrX_+_51927918 0.031 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chrX_+_119737743 0.031 NM_014060
MCTS1
malignant T cell amplified sequence 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.47 1.43e-04 GO:0050794 regulation of cellular process
1.40 5.72e-04 GO:0065007 biological regulation
1.78 6.57e-04 GO:0060255 regulation of macromolecule metabolic process
2.04 7.10e-04 GO:0048523 negative regulation of cellular process
3.21 9.98e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 1.23e-03 GO:0050789 regulation of biological process
3.07 1.24e-03 GO:0031327 negative regulation of cellular biosynthetic process
5.27 1.36e-03 GO:0001701 in utero embryonic development
3.01 1.79e-03 GO:0009890 negative regulation of biosynthetic process
3.07 2.15e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.61 2.34e-03 GO:0044260 cellular macromolecule metabolic process
1.69 3.55e-03 GO:0031323 regulation of cellular metabolic process
1.89 4.14e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.69 4.48e-03 GO:0080090 regulation of primary metabolic process
1.90 4.54e-03 GO:0048519 negative regulation of biological process
1.81 7.43e-03 GO:0031326 regulation of cellular biosynthetic process
1.84 8.89e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.99 9.15e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 1.04e-02 GO:0009889 regulation of biosynthetic process
2.95 1.11e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.60 1.44e-02 GO:0019222 regulation of metabolic process
1.22 1.49e-02 GO:0009987 cellular process
2.52 1.58e-02 GO:0031324 negative regulation of cellular metabolic process
2.77 1.81e-02 GO:0009790 embryo development
2.49 1.92e-02 GO:0010605 negative regulation of macromolecule metabolic process
3.02 2.16e-02 GO:0051253 negative regulation of RNA metabolic process
2.41 2.29e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 2.41e-02 GO:0043170 macromolecule metabolic process
2.40 2.63e-02 GO:0009892 negative regulation of metabolic process
3.52 2.91e-02 GO:0044419 interspecies interaction between organisms
3.43 3.94e-02 GO:0009792 embryo development ending in birth or egg hatching
2.50 3.96e-02 GO:0031328 positive regulation of cellular biosynthetic process
3.10 4.25e-02 GO:0072358 cardiovascular system development
3.10 4.25e-02 GO:0072359 circulatory system development
3.81 4.44e-02 GO:0001944 vasculature development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 2.86e-04 GO:0044424 intracellular part
1.22 6.46e-04 GO:0005622 intracellular
1.48 9.20e-04 GO:0005634 nucleus
10.72 3.32e-03 GO:0017053 transcriptional repressor complex
10.07 2.29e-02 GO:0000118 histone deacetylase complex
1.23 2.53e-02 GO:0043229 intracellular organelle
1.23 2.82e-02 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.20 3.20e-02 GO:0001071 nucleic acid binding transcription factor activity
2.20 3.20e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
78.55 3.70e-02 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity