Motif ID: GUGCAAA

Z-value: 1.277


Mature miRNA associated with seed GUGCAAA:

NamemiRBase Accession
hsa-miR-19a MIMAT0000073
hsa-miR-19b MIMAT0000074



Activity profile for motif GUGCAAA.

activity profile for motif GUGCAAA


Sorted Z-values histogram for motif GUGCAAA

Sorted Z-values for motif GUGCAAA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUGCAAA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_132272311 6.959 NM_001901
CTGF
connective tissue growth factor
chr2_+_8822112 6.245 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr13_+_36050885 5.699 NM_001204197
NBEA
neurobeachin
chr1_+_183605207 4.958 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr13_+_35516390 4.943 NM_015678
NBEA
neurobeachin
chr4_+_75858205 4.639 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr2_+_121103670 4.357 NM_002193
INHBB
inhibin, beta B
chr10_+_115803805 4.111 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr6_-_90121966 4.056 NM_021244
RRAGD
Ras-related GTP binding D
chr4_-_149363498 4.011 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr3_-_9994057 3.932 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr4_+_55523906 3.914 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr9_+_34458810 3.593 NM_012144
DNAI1
dynein, axonemal, intermediate chain 1
chr1_-_46598250 3.396 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr8_-_110657745 3.270 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr6_+_16129285 3.235 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chr8_-_110657025 3.199 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr8_-_110661007 3.134 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr22_-_39548448 3.128 NM_175709
CBX7
chromobox homolog 7
chr7_+_114055048 3.122 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.47 1.36e-02 GO:0070647 protein modification by small protein conjugation or removal
2.43 1.33e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.34 2.06e-05 GO:0007167 enzyme linked receptor protein signaling pathway
2.28 1.78e-02 GO:0007243 intracellular protein kinase cascade
2.28 1.78e-02 GO:0023014 signal transduction via phosphorylation event
2.14 3.54e-03 GO:0010629 negative regulation of gene expression
1.98 6.07e-03 GO:0006468 protein phosphorylation
1.89 1.54e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.86 7.68e-06 GO:0007399 nervous system development
1.82 4.27e-02 GO:0016310 phosphorylation
1.65 1.98e-02 GO:0035556 intracellular signal transduction
1.62 2.63e-02 GO:0009966 regulation of signal transduction
1.61 2.43e-03 GO:0006464 protein modification process
1.59 1.48e-02 GO:0023051 regulation of signaling
1.55 8.10e-03 GO:0043412 macromolecule modification
1.52 1.63e-02 GO:0030154 cell differentiation
1.49 3.41e-03 GO:0010468 regulation of gene expression
1.49 3.18e-02 GO:0048869 cellular developmental process
1.47 2.76e-02 GO:0051252 regulation of RNA metabolic process
1.42 6.58e-04 GO:0031323 regulation of cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.58 3.69e-02 GO:0035770 RNA granule
1.26 3.94e-03 GO:0005634 nucleus
1.16 4.04e-02 GO:0005737 cytoplasm
1.15 1.10e-05 GO:0005622 intracellular
1.15 3.39e-05 GO:0044424 intracellular part
1.07 5.07e-03 GO:0044464 cell part
1.07 5.17e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
4.41 3.00e-02 GO:0004221 ubiquitin thiolesterase activity
2.40 2.59e-04 GO:0004674 protein serine/threonine kinase activity
1.96 9.30e-03 GO:0004672 protein kinase activity
1.95 1.76e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.92 1.38e-03 GO:0016301 kinase activity
1.72 2.17e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.49 6.17e-03 GO:0008270 zinc ion binding
1.48 2.17e-03 GO:0000166 nucleotide binding
1.47 3.26e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.46 2.90e-02 GO:0017076 purine nucleotide binding
1.46 3.76e-02 GO:0032553 ribonucleotide binding
1.46 3.76e-02 GO:0032555 purine ribonucleotide binding
1.42 1.82e-05 GO:0046872 metal ion binding
1.41 2.65e-05 GO:0043169 cation binding
1.41 3.20e-05 GO:0043167 ion binding
1.26 3.35e-05 GO:0005515 protein binding
1.14 8.08e-05 GO:0005488 binding