Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.304


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
UBTFchr17_-_42297037,
chr17_-_42298228
0.431.7e-02Click!
HMGB2chr4_-_174254730-0.346.2e-02Click!
SSRP1chr11_-_571033240.241.9e-01Click!
HMGB3chrX_+_150151757-0.115.8e-01Click!
HBP1chr7_+_1068094050.058.1e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_135782246 10.671 NM_001018046
NM_025052
YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr13_+_24144402 5.786 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr17_+_36861398 5.761 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr19_+_55888203 5.708 NM_139172
TMEM190
transmembrane protein 190
chr3_+_63638343 5.474 NM_001080537
SNTN
sentan, cilia apical structure protein
chr3_-_148939784 5.468 NM_000096
CP
ceruloplasmin (ferroxidase)
chr7_+_114055048 5.201 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr4_-_16085666 4.859 PROM1
prominin 1
chr7_-_16921596 4.852 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr5_+_94727047 4.847 NM_152548
FAM81B
family with sequence similarity 81, member B
chr3_+_186648515 4.721 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr11_+_36317724 4.297 NM_001160167
PRR5L
proline rich 5 like
chr5_+_121465214 4.192 NM_207317
ZNF474
zinc finger protein 474
chrX_+_106449861 4.181 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr18_-_53071225 4.160 NM_001243232
TCF4
transcription factor 4
chr3_+_171561138 4.102 NM_001164436
TMEM212
transmembrane protein 212
chr4_-_16085593 4.041 NM_001145847
NM_001145848
PROM1

prominin 1

chr6_-_139613114 4.000 NM_153235
TXLNB
taxilin beta
chr18_-_45663667 3.911 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr6_-_32557431 3.846 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr2_-_86564632 3.832 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr12_+_69742130 3.776 NM_000239
LYZ
lysozyme
chr13_+_43355685 3.769 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr14_-_92413738 3.671 FBLN5
fibulin 5
chr19_+_13134782 3.606 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_-_53177999 3.587 NM_001243231
TCF4
transcription factor 4
chr4_+_52917440 3.580 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr13_-_39564857 3.567 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr18_-_52988916 3.537 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr6_+_116937641 3.518 NM_001010892
NM_001161664
RSPH4A

radial spoke head 4 homolog A (Chlamydomonas)

chr11_+_61976139 3.467 NM_002407
SCGB2A1
secretoglobin, family 2A, member 1
chr22_-_50971007 3.432 NM_001014440
ODF3B
outer dense fiber of sperm tails 3B
chr1_+_244216506 3.432 NM_006352
ZNF238
zinc finger protein 238
chr13_+_50589389 3.383 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr11_+_73359734 3.374 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_-_117107700 3.371 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr8_-_72273965 3.339 EYA1
eyes absent homolog 1 (Drosophila)
chr3_-_57530067 3.209 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr7_+_116660263 3.193 ST7
suppression of tumorigenicity 7
chr11_+_6897855 3.149 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr3_-_149510609 3.077 NM_001144960
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr11_-_85430117 3.057 NM_206929
SYTL2
synaptotagmin-like 2
chr11_-_85430382 3.050 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr5_-_121414011 2.946 NM_002317
LOX
lysyl oxidase
chr6_-_29527477 2.924 UBD
ubiquitin D
chr1_+_244214576 2.912 ZNF238
zinc finger protein 238
chr14_+_21156922 2.862 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr5_-_137475076 2.824 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr22_-_50970542 2.805 ODF3B
outer dense fiber of sperm tails 3B
chr12_+_69742140 2.790 LYZ
lysozyme
chr20_-_3762060 2.789 NM_015417
SPEF1
sperm flagellar 1
chr14_-_92414004 2.740 NM_006329
FBLN5
fibulin 5
chr8_-_72274466 2.712 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_32497925 2.711 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr20_+_51588945 2.683 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr3_+_181429711 2.675 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr7_+_142829169 2.663 NM_002652
PIP
prolactin-induced protein
chr6_-_29527701 2.648 NM_006398
UBD
ubiquitin D
chr11_-_115088628 2.611 CADM1
cell adhesion molecule 1
chr5_-_121413906 2.598 LOX
lysyl oxidase
chr6_-_76203256 2.586 NM_015687
FILIP1
filamin A interacting protein 1
chr5_+_140254930 2.556 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr9_-_117150217 2.555 AKNA
AT-hook transcription factor
chr3_-_120400957 2.540 HGD
homogentisate 1,2-dioxygenase
chr3_-_167371288 2.539 NM_178824
WDR49
WD repeat domain 49
chr11_+_71791376 2.538 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr5_-_121413967 2.512 LOX
lysyl oxidase
chr18_-_53257033 2.507 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr6_-_130031278 2.480 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr20_+_18794369 2.435 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr10_-_32667543 2.418 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr3_+_181417387 2.406 SOX2-OT
SOX2 overlapping transcript (non-protein coding)
chrX_-_13835187 2.400 GPM6B
glycoprotein M6B
chr10_-_21435487 2.384 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr5_+_140186658 2.383 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr7_+_105603656 2.376 NM_152750
CDHR3
cadherin-related family member 3
chr14_-_89883306 2.370 NM_005197
FOXN3
forkhead box N3
chr1_+_3607232 2.365 NM_001126240
NM_001126241
NM_001126242
NM_001204189
NM_001204190
NM_001204191
TP73





tumor protein p73





chr10_-_123356158 2.347 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr12_-_24103842 2.326 SOX5
SRY (sex determining region Y)-box 5
chr12_-_111358353 2.316 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr2_-_157189040 2.311 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr10_+_115511212 2.307 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr7_-_131241321 2.305 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr11_-_85397215 2.254 NM_152723
CCDC89
coiled-coil domain containing 89
chrX_-_13835012 2.244 GPM6B
glycoprotein M6B
chr9_+_135753711 2.229 C9orf9
chromosome 9 open reading frame 9
chr14_-_20774089 2.221 TTC5
tetratricopeptide repeat domain 5
chr14_-_20774129 2.220 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr9_+_135754284 2.211 NM_018956
C9orf9
chromosome 9 open reading frame 9
chr3_-_114790221 2.171 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr9_-_4300028 2.168 NM_001042413
GLIS3
GLIS family zinc finger 3
chr5_+_140213968 2.163 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr1_+_244214552 2.147 NM_205768
ZNF238
zinc finger protein 238
chr11_+_71900958 2.138 NM_000802
FOLR1
folate receptor 1 (adult)
chr6_+_135502521 2.122 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr4_-_105416050 2.054 CXXC4
CXXC finger protein 4
chr3_+_3841079 2.053 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr7_+_116660291 2.040 ST7
suppression of tumorigenicity 7
chr9_-_4152182 2.034 NM_152629
GLIS3
GLIS family zinc finger 3
chr4_+_36285643 2.018 NM_001170700
DTHD1
death domain containing 1
chr9_-_3223007 2.002


chr10_-_62332666 1.988 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr13_+_36050885 1.980 NM_001204197
NBEA
neurobeachin
chrX_-_38186782 1.974 NM_000328
NM_001034853
RPGR

retinitis pigmentosa GTPase regulator

chr3_-_71353910 1.920 NM_001244812
FOXP1
forkhead box P1
chr5_+_156820161 1.909 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr16_-_21314371 1.900 NM_001014444
NM_001888
CRYM

crystallin, mu

chr13_-_36429798 1.898 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr18_-_53089722 1.893 NM_001243233
TCF4
transcription factor 4
chr1_-_217250230 1.889 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr6_+_131958441 1.852 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_-_160472960 1.841 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr1_+_61547388 1.828 NM_001145512
NFIA
nuclear factor I/A
chrX_-_38186619 1.810 RPGR
retinitis pigmentosa GTPase regulator
chr3_+_181430075 1.806 SOX2
SRY (sex determining region Y)-box 2
chr10_-_61900659 1.796 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_167298382 1.789 POU2F1
POU class 2 homeobox 1
chr19_+_13135368 1.771 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr6_+_135502445 1.768 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr17_+_17876126 1.758 NM_001130090
NM_001130091
NM_001130092
NM_031294
LRRC48



leucine rich repeat containing 48



chr17_+_7591666 1.751 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chrX_-_13835213 1.741 GPM6B
glycoprotein M6B
chrX_-_13835313 1.741 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr6_-_31681845 1.717


chr1_-_75139421 1.716 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr1_+_61547625 1.708 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr4_-_100356449 1.708 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_+_86668428 1.659 KDM3A
lysine (K)-specific demethylase 3A
chr3_-_112359547 1.629 CCDC80
coiled-coil domain containing 80
chr6_+_89790464 1.628 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_32920812 1.627 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr6_+_135502477 1.600 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr2_+_86668270 1.587 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr4_-_100356290 1.572 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_57285368 1.563 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr1_+_155099935 1.559 EFNA1
ephrin-A1
chr3_-_66024508 1.558 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr16_-_53737713 1.557 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr8_+_79578258 1.556 NM_016010
FAM164A
family with sequence similarity 164, member A
chr3_-_114478117 1.547 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr17_-_56065474 1.546 VEZF1
vascular endothelial zinc finger 1
chr5_+_36876899 1.535 NIPBL
Nipped-B homolog (Drosophila)
chr3_+_151488214 1.531 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr19_-_44831907 1.520 ZFP112
zinc finger protein 112 homolog (mouse)
chr5_-_168271852 1.495


chr16_+_810764 1.487 NM_005823
NM_001177355
MSLN

mesothelin

chr5_-_121814781 1.479


chr9_-_124989755 1.477 NM_001242334
LHX6
LIM homeobox 6
chr12_-_71551564 1.473 TSPAN8
tetraspanin 8
chr11_+_36397534 1.473 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr19_+_13135745 1.470 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_56065596 1.467 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr3_-_187454247 1.466 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr22_+_39052628 1.445 NM_001002880
NM_015373
CBY1

chibby homolog 1 (Drosophila)

chr4_+_25657434 1.433 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr1_-_41625539 1.433 NM_001172222
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr3_-_112359443 1.412 CCDC80
coiled-coil domain containing 80
chr2_+_162272892 1.410 TBR1
T-box, brain, 1
chr8_-_110693233 1.404 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr17_+_36861857 1.401 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr4_+_36283243 1.401 NM_001136536
DTHD1
death domain containing 1
chr20_-_44175995 1.400 NM_001198986
NM_020398
SPINLW1-WFDC6
SPINLW1
SPINLW1-WFDC6 readthrough
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr3_-_112359565 1.393 CCDC80
coiled-coil domain containing 80
chr2_+_86668488 1.386 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr15_-_40401041 1.386 NM_001003940
BMF
Bcl2 modifying factor
chr6_+_148663728 1.378 NM_015278
SASH1
SAM and SH3 domain containing 1
chr5_+_172483285 1.378 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr8_-_124553448 1.377 NM_001242463
NM_058229
FBXO32

F-box protein 32

chrY_+_2803111 1.376 NM_001145276
ZFY
zinc finger protein, Y-linked
chr7_-_99869772 1.374 NM_178831
GATS
GATS, stromal antigen 3 opposite strand
chr4_+_55523906 1.374 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr4_-_100273831 1.370 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr1_+_12806162 1.369 NM_152290
C1orf158
chromosome 1 open reading frame 158
chr2_+_61389628 1.368 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr14_-_61190458 1.362 NM_017420
SIX4
SIX homeobox 4
chr4_+_72102249 1.360 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_-_49242406 1.357 NM_024603
BEND5
BEN domain containing 5
chr9_-_117156684 1.348 NM_030767
AKNA
AT-hook transcription factor
chr16_+_57769667 1.342 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr6_-_32634287 1.338 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr18_+_72922725 1.331 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr20_+_32150139 1.327 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr2_-_188312872 1.324 NM_005795
CALCRL
calcitonin receptor-like
chr7_-_139876718 1.314 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr11_+_101785720 1.314 NM_020802
KIAA1377
KIAA1377
chr5_+_138677546 1.313 PAIP2
poly(A) binding protein interacting protein 2
chr5_+_140571903 1.308 NM_018930
PCDHB10
protocadherin beta 10
chr6_+_89790412 1.303 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr15_+_78556485 1.302 NM_018602
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr12_-_49582800 1.301 NM_006009
TUBA1A
tubulin, alpha 1a
chr5_+_140235594 1.287 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr5_-_41213513 1.280 NM_000065
C6
complement component 6
chr2_-_213403280 1.277 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr6_+_148663953 1.270 SASH1
SAM and SH3 domain containing 1
chr2_-_86565205 1.269 NM_001164730
REEP1
receptor accessory protein 1
chr1_-_32801606 1.267 NM_023009
MARCKSL1
MARCKS-like 1
chr5_+_138677570 1.266 PAIP2
poly(A) binding protein interacting protein 2
chr8_-_108510094 1.263 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr4_-_168155576 1.260 NM_001204353
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.92 5.17e-09 GO:0010629 negative regulation of gene expression
1.80 1.11e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.03 3.79e-06 GO:0016568 chromatin modification
1.83 5.01e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.73 8.49e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.79 1.54e-05 GO:0051253 negative regulation of RNA metabolic process
1.34 3.07e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.84 3.19e-05 GO:0006325 chromatin organization
1.68 4.97e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.25 5.56e-05 GO:0032502 developmental process
2.60 6.04e-05 GO:0007156 homophilic cell adhesion
1.16 8.91e-05 GO:0050794 regulation of cellular process
1.32 1.10e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.31 1.29e-04 GO:0010468 regulation of gene expression
1.64 1.62e-04 GO:0009890 negative regulation of biosynthetic process
1.33 1.78e-04 GO:0051252 regulation of RNA metabolic process
1.27 1.85e-04 GO:0048856 anatomical structure development
1.54 3.12e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.52 3.32e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.67 3.45e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 5.23e-04 GO:0007275 multicellular organismal development
1.32 6.44e-04 GO:0006355 regulation of transcription, DNA-dependent
1.65 6.52e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.53 7.90e-04 GO:0006351 transcription, DNA-dependent
1.50 9.14e-04 GO:0009892 negative regulation of metabolic process
1.14 1.81e-03 GO:0050789 regulation of biological process
1.62 1.87e-03 GO:0051276 chromosome organization
1.61 2.62e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.77 2.93e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.90 2.96e-03 GO:0016337 cell-cell adhesion
1.13 3.17e-03 GO:0065007 biological regulation
1.55 3.37e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.58 4.14e-03 GO:0051254 positive regulation of RNA metabolic process
1.26 5.14e-03 GO:0031326 regulation of cellular biosynthetic process
1.28 5.75e-03 GO:0048519 negative regulation of biological process
1.25 8.05e-03 GO:0048731 system development
1.52 8.18e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 8.38e-03 GO:0032774 RNA biosynthetic process
1.47 1.01e-02 GO:0031324 negative regulation of cellular metabolic process
1.25 1.07e-02 GO:0009889 regulation of biosynthetic process
1.55 1.15e-02 GO:0010628 positive regulation of gene expression
1.35 1.22e-02 GO:0007399 nervous system development
1.28 2.07e-02 GO:0048523 negative regulation of cellular process
1.49 2.13e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.24 2.43e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 3.86e-02 GO:0060255 regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.28 2.44e-14 GO:0005634 nucleus
1.10 2.53e-08 GO:0005622 intracellular
1.10 8.64e-08 GO:0044424 intracellular part
1.13 1.26e-06 GO:0043231 intracellular membrane-bounded organelle
1.13 1.69e-06 GO:0043227 membrane-bounded organelle
1.12 4.46e-06 GO:0043229 intracellular organelle
1.11 5.55e-06 GO:0043226 organelle
1.63 1.39e-05 GO:0044451 nucleoplasm part
1.34 1.80e-05 GO:0044428 nuclear part
1.37 1.90e-05 GO:0031981 nuclear lumen
3.88 3.47e-03 GO:0000932 cytoplasmic mRNA processing body
1.92 3.48e-03 GO:0016604 nuclear body
1.34 1.00e-02 GO:0005654 nucleoplasm
2.93 1.31e-02 GO:0035770 RNA granule
4.27 1.45e-02 GO:0070603 SWI/SNF-type complex
2.36 1.95e-02 GO:0016585 chromatin remodeling complex
2.17 1.96e-02 GO:0016607 nuclear speck
2.41 3.02e-02 GO:0000790 nuclear chromatin
4.78 3.31e-02 GO:0016514 SWI/SNF complex
1.23 4.00e-02 GO:0043233 organelle lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.32 6.71e-09 GO:0003676 nucleic acid binding
1.40 1.30e-08 GO:0003677 DNA binding
1.09 5.86e-07 GO:0005488 binding
1.38 1.33e-06 GO:0008270 zinc ion binding
1.51 6.56e-05 GO:0001071 nucleic acid binding transcription factor activity
1.51 6.56e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.14 6.92e-05 GO:0005515 protein binding
1.50 7.02e-05 GO:0030528 transcription regulator activity
1.29 3.66e-04 GO:0046914 transition metal ion binding
1.79 3.69e-04 GO:0000988 protein binding transcription factor activity
1.79 3.69e-04 GO:0000989 transcription factor binding transcription factor activity
1.77 6.78e-04 GO:0003712 transcription cofactor activity
1.19 5.46e-03 GO:0046872 metal ion binding
1.51 6.49e-03 GO:0043565 sequence-specific DNA binding
1.18 8.82e-03 GO:0043169 cation binding
1.18 1.15e-02 GO:0043167 ion binding
1.70 2.98e-02 GO:0016564 transcription repressor activity
1.69 3.33e-02 GO:0016563 transcription activator activity