Motif ID: HES1.p2

Z-value: 1.431


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HES1chr3_+_193853937-0.431.7e-02Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_50355278 3.992 NM_001651
AQP5
aquaporin 5
chr5_+_131630065 3.753 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr22_-_50765405 3.116 NM_001001794
FAM116B
family with sequence similarity 116, member B
chr9_+_36136710 2.883 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr2_+_228736326 2.858 NM_178821
WDR69
WD repeat domain 69
chr20_-_3154169 2.817 ProSAPiP1
ProSAPiP1 protein
chr5_-_180018465 2.775 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr7_+_106685007 2.739 NM_002736
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr2_-_130902568 2.712 NM_207310
CCDC74B
coiled-coil domain containing 74B
chr1_+_111889194 2.700 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr6_-_132272311 2.649 NM_001901
CTGF
connective tissue growth factor
chr11_-_46867788 2.635 CKAP5
cytoskeleton associated protein 5
chr9_-_138391696 2.366 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr11_+_111385509 2.313 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr7_+_102105459 2.301 LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr11_+_61276271 2.162 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr17_-_30186217 2.009 NM_018405
C17orf79
chromosome 17 open reading frame 79
chr11_+_46299161 1.900 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr17_+_35849950 1.864 NM_007026
DUSP14
dual specificity phosphatase 14
chr1_-_223537400 1.834 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr1_-_94374986 1.817 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr1_-_109656478 1.797 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr14_+_105953256 1.748 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr2_-_10588451 1.726 NM_002539
ODC1
ornithine decarboxylase 1
chr5_+_156693051 1.723 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr1_+_227127959 1.700 ADCK3
aarF domain containing kinase 3
chr17_-_3867585 1.697 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr1_+_227127937 1.692 NM_020247
ADCK3
aarF domain containing kinase 3
chr22_+_29279573 1.683 NM_001206998
ZNRF3
zinc and ring finger 3
chr1_+_228871109 1.673 RHOU
ras homolog gene family, member U
chr2_-_62733475 1.659 NM_198276
TMEM17
transmembrane protein 17
chr20_+_56725982 1.612 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr15_-_56757239 1.611 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr13_+_35516390 1.594 NM_015678
NBEA
neurobeachin
chr1_+_227127993 1.584 ADCK3
aarF domain containing kinase 3
chr19_-_3028901 1.574 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr22_-_41593466 1.556


chr14_+_105953531 1.553 CRIP1
cysteine-rich protein 1 (intestinal)
chr6_+_19837599 1.550 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr17_+_1633754 1.547 WDR81
WD repeat domain 81
chr1_+_236305831 1.520 NM_003272
GPR137B
G protein-coupled receptor 137B
chr1_+_227127999 1.512 ADCK3
aarF domain containing kinase 3
chr16_+_2525108 1.489 NM_001199107
NM_020705
TBC1D24

TBC1 domain family, member 24

chr5_+_176237435 1.482 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr2_-_27712520 1.480 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr7_+_94139331 1.425 CASD1
CAS1 domain containing 1
chr3_+_54156573 1.425 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr16_-_54962707 1.409 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr5_+_75699003 1.407 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr20_+_36531548 1.405 VSTM2L
V-set and transmembrane domain containing 2 like
chrX_+_152240726 1.391 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr12_+_56661026 1.380 NM_001099337
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr12_-_107487585 1.371 NM_004075
CRY1
cryptochrome 1 (photolyase-like)
chr16_+_58283819 1.366 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr6_+_17281773 1.349 NM_001143942
RBM24
RNA binding motif protein 24
chr2_+_8822112 1.333 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr8_+_120885899 1.325 NM_022783
DEPTOR
DEP domain containing MTOR-interacting protein
chr6_+_57037333 1.324 BAG2
BCL2-associated athanogene 2
chr1_-_23751126 1.317 NM_003196
TCEA3
transcription elongation factor A (SII), 3
chr20_+_36531498 1.306 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chrY_+_22917953 1.297 NM_001039567
RPS4Y2
ribosomal protein S4, Y-linked 2
chr14_-_89883306 1.282 NM_005197
FOXN3
forkhead box N3
chr2_+_132285469 1.277 NM_138770
CCDC74A
coiled-coil domain containing 74A
chr17_+_35849997 1.274 DUSP14
dual specificity phosphatase 14
chr2_+_176994421 1.263 NM_001199747
NM_001199746
NM_019558
HOXD8


homeobox D8


chr8_-_97273795 1.249 NM_015942
MTERFD1
MTERF domain containing 1
chr20_-_35580109 1.246 SAMHD1
SAM domain and HD domain 1
chr5_+_612404 1.238 NM_018140
CEP72
centrosomal protein 72kDa
chr19_-_55972935 1.208 ISOC2
isochorismatase domain containing 2
chr20_-_35580175 1.204 SAMHD1
SAM domain and HD domain 1
chr18_-_12377168 1.202 AFG3L2
AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr10_+_120789227 1.199 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr1_+_245133652 1.197 EFCAB2
EF-hand calcium binding domain 2
chr9_+_124922189 1.197 NM_198469
MORN5
MORN repeat containing 5
chr11_+_1244292 1.187 NM_002458
MUC5B
mucin 5B, oligomeric mucus/gel-forming
chr20_-_35580186 1.178 NM_015474
SAMHD1
SAM domain and HD domain 1
chr11_-_86383355 1.163 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr1_-_159869897 1.159 NM_012337
CCDC19
coiled-coil domain containing 19
chr5_+_612454 1.150 CEP72
centrosomal protein 72kDa
chr16_+_67596309 1.134 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr1_+_61547625 1.133 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr15_+_50474357 1.131 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr6_-_86388419 1.127 SNHG5
small nucleolar RNA host gene 5 (non-protein coding)
chr7_+_94138991 1.125 NM_022900
CASD1
CAS1 domain containing 1
chr2_-_99552677 1.114 NM_207362
C2orf55
chromosome 2 open reading frame 55
chr8_+_144099900 1.112 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr7_+_102105367 1.103 NM_152892
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr10_-_28287790 1.099 NM_018076
ARMC4
armadillo repeat containing 4
chr16_+_29817810 1.095 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr1_+_118472364 1.094 NM_006784
WDR3
WD repeat domain 3
chr16_+_84178864 1.094 NM_178452
DNAAF1
dynein, axonemal, assembly factor 1
chr12_-_121905036 1.091 KDM2B
lysine (K)-specific demethylase 2B
chr3_-_142297650 1.089 NM_001184
ATR
ataxia telangiectasia and Rad3 related
chr7_-_158380360 1.085 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr20_-_35580045 1.083 SAMHD1
SAM domain and HD domain 1
chr2_+_10183630 1.081 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr11_+_66045645 1.075 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr6_+_88117689 1.074 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr3_-_47823419 1.061 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr2_-_172750724 1.059 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr1_+_244998592 1.047 NM_198076
FAM36A
family with sequence similarity 36, member A
chr6_+_157099041 1.016 NM_017519
NM_020732
ARID1B

AT rich interactive domain 1B (SWI1-like)

chr6_+_135502477 1.014 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr7_-_131241321 1.004 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr16_-_52580805 1.002 NM_001080430
TOX3
TOX high mobility group box family member 3
chr3_+_138327918 0.998 NM_018147
FAIM
Fas apoptotic inhibitory molecule
chr1_-_94374949 0.994 GCLM
glutamate-cysteine ligase, modifier subunit
chr7_+_90225607 0.986 CDK14
cyclin-dependent kinase 14
chr9_-_3525721 0.985 RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr12_-_120554558 0.975 RAB35
RAB35, member RAS oncogene family
chr14_+_103243813 0.973 NM_001199427
NM_003300
NM_145725
NM_145726
TRAF3



TNF receptor-associated factor 3



chr21_+_34697197 0.972 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr17_+_26646120 0.969 NM_014573
TMEM97
transmembrane protein 97
chr2_+_11295539 0.965 NM_152391
PQLC3
PQ loop repeat containing 3
chr15_-_93616308 0.964 RGMA
RGM domain family, member A
chr2_+_85766291 0.963 MAT2A
methionine adenosyltransferase II, alpha
chr3_-_127842566 0.960 NM_003707
RUVBL1
RuvB-like 1 (E. coli)
chr16_+_28303622 0.960 NM_001024401
SBK1
SH3-binding domain kinase 1
chr19_+_32896515 0.954 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr19_+_39833096 0.950 SAMD4B
sterile alpha motif domain containing 4B
chr8_+_75262616 0.949 NM_018972
NM_001040875
GDAP1

ganglioside-induced differentiation-associated protein 1

chr10_-_99094427 0.944 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr3_-_142297565 0.943 ATR
ataxia telangiectasia and Rad3 related
chr5_-_79950783 0.938 NM_000791
DHFR
dihydrofolate reductase
chr11_-_86383164 0.936 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr4_+_15480833 0.932 CC2D2A
coiled-coil and C2 domain containing 2A
chr14_+_103243832 0.931 TRAF3
TNF receptor-associated factor 3
chr1_-_94375028 0.925 GCLM
glutamate-cysteine ligase, modifier subunit
chr20_-_20693122 0.913 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr5_-_472916 0.912 PP7080
uncharacterized LOC25845
chr15_-_93632161 0.905 NM_020211
RGMA
RGM domain family, member A
chr3_-_13008959 0.899 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr11_+_125757591 0.895 HYLS1
hydrolethalus syndrome 1
chr3_+_138327541 0.881 NM_001033030
NM_001033031
NM_001033032
FAIM


Fas apoptotic inhibitory molecule


chr1_+_25757381 0.879 NM_018202
TMEM57
transmembrane protein 57
chr9_-_88714460 0.872 GOLM1
golgi membrane protein 1
chr1_-_67390413 0.866 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr2_+_10184371 0.865 NM_001177718
KLF11
Kruppel-like factor 11
chr11_+_109964086 0.863 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr9_+_96338671 0.862 NM_005392
PHF2
PHD finger protein 2
chr9_-_88714486 0.862 NM_016548
GOLM1
golgi membrane protein 1
chr17_-_4693595 0.861 LOC284014
uncharacterized LOC284014
chr17_+_17876126 0.861 NM_001130090
NM_001130091
NM_001130092
NM_031294
LRRC48



leucine rich repeat containing 48



chr3_-_47823337 0.856 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr15_-_93616358 0.856 NM_001166286
RGMA
RGM domain family, member A
chr15_-_93631751 0.854 NM_001166287
RGMA
RGM domain family, member A
chr7_-_148581297 0.849 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_+_9599546 0.848 SLC25A33
solute carrier family 25, member 33
chr14_-_53019036 0.848 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr6_+_135502521 0.847 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr1_+_15250578 0.844 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr18_-_12377248 0.842 NM_006796
AFG3L2
AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr6_+_57037058 0.837 NM_004282
BAG2
BCL2-associated athanogene 2
chr7_-_148581379 0.834 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr15_+_76352270 0.831 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr11_-_6440288 0.828 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_+_30710461 0.824 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr14_+_67999915 0.824 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr3_-_47823368 0.807 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr19_-_39340362 0.804 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr12_-_108954952 0.790 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr11_-_8615412 0.790 NM_030906
STK33
serine/threonine kinase 33
chr15_+_40697977 0.789 IVD
isovaleryl-CoA dehydrogenase
chr1_-_226111803 0.787 PYCR2
pyrroline-5-carboxylate reductase family, member 2
chr7_+_150065330 0.787 REPIN1
replication initiator 1
chr3_-_187871816 0.787 LPP-AS2
LPP antisense RNA 2 (non-protein coding)
chr19_-_18717467 0.786 CRLF1
cytokine receptor-like factor 1
chr1_-_114302093 0.785 PHTF1
putative homeodomain transcription factor 1
chrX_-_8700170 0.783 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr10_+_12391728 0.782 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr12_-_108954942 0.781 SART3
squamous cell carcinoma antigen recognized by T cells 3
chr4_-_177116713 0.777 NM_144644
SPATA4
spermatogenesis associated 4
chr17_-_40273304 0.769 NM_021078
KAT2A
K(lysine) acetyltransferase 2A
chr15_+_40698000 0.767 IVD
isovaleryl-CoA dehydrogenase
chr18_-_45935627 0.765 ZBTB7C
zinc finger and BTB domain containing 7C
chr14_+_74035865 0.762 ACOT2
acyl-CoA thioesterase 2
chr2_+_242641310 0.759 NM_032329
ING5
inhibitor of growth family, member 5
chr14_+_74003817 0.757 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr8_-_144691622 0.755 NM_023078
PYCRL
pyrroline-5-carboxylate reductase-like
chr20_+_42086468 0.753 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr12_-_49525271 0.753 NM_006082
TUBA1B
tubulin, alpha 1b
chr8_+_96037186 0.752 NM_152416
C8orf38
chromosome 8 open reading frame 38
chr6_-_154831788 0.750 CNKSR3
CNKSR family member 3
chr20_-_4982133 0.750 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr13_-_50159628 0.747 RCBTB1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr16_-_1968230 0.740 NM_001009606
HS3ST6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr17_-_10101854 0.740 NM_201433
GAS7
growth arrest-specific 7
chr3_-_107809754 0.739 NM_001777
NM_198793
CD47

CD47 molecule

chr10_+_49514652 0.735 MAPK8
mitogen-activated protein kinase 8
chr11_-_119234628 0.735 USP2
ubiquitin specific peptidase 2
chr2_+_61293038 0.735 KIAA1841
KIAA1841
chr16_+_699277 0.731 NM_145294
WDR90
WD repeat domain 90
chr1_-_32801606 0.727 NM_023009
MARCKSL1
MARCKS-like 1
chr10_+_92922696 0.726 PCGF5
polycomb group ring finger 5
chr6_-_154831652 0.726 CNKSR3
CNKSR family member 3
chr9_+_127615695 0.723 NM_001045476
WDR38
WD repeat domain 38
chr1_-_217262946 0.723 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr9_-_126030792 0.717 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chrX_-_108868250 0.716 NM_012282
KCNE1L
KCNE1-like
chr1_-_6761897 0.716 NM_018198
DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 9.92e-25 GO:0044237 cellular metabolic process
1.37 1.37e-22 GO:0044260 cellular macromolecule metabolic process
1.24 1.98e-19 GO:0008152 metabolic process
1.24 6.81e-17 GO:0044238 primary metabolic process
1.43 9.42e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 1.00e-16 GO:0006807 nitrogen compound metabolic process
1.39 1.36e-16 GO:0034641 cellular nitrogen compound metabolic process
1.29 1.81e-16 GO:0043170 macromolecule metabolic process
1.46 1.77e-14 GO:0090304 nucleic acid metabolic process
2.10 1.07e-10 GO:0016568 chromatin modification
1.11 1.85e-10 GO:0009987 cellular process
1.37 3.57e-10 GO:0044249 cellular biosynthetic process
1.36 9.77e-10 GO:0009058 biosynthetic process
1.44 2.83e-09 GO:0016070 RNA metabolic process
2.45 1.02e-08 GO:0016569 covalent chromatin modification
2.46 1.43e-08 GO:0016570 histone modification
1.39 3.39e-08 GO:0043412 macromolecule modification
1.72 6.56e-08 GO:0051276 chromosome organization
1.39 1.15e-07 GO:0006464 protein modification process
1.72 2.21e-07 GO:0006259 DNA metabolic process
1.32 2.65e-07 GO:0044267 cellular protein metabolic process
1.80 4.11e-07 GO:0006325 chromatin organization
1.37 6.35e-07 GO:0010467 gene expression
1.39 1.21e-06 GO:0006996 organelle organization
1.38 2.03e-06 GO:0009059 macromolecule biosynthetic process
2.24 2.97e-06 GO:0006260 DNA replication
1.37 7.17e-06 GO:0034645 cellular macromolecule biosynthetic process
1.53 1.49e-05 GO:0033554 cellular response to stress
1.26 6.85e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.64 8.20e-05 GO:0016071 mRNA metabolic process
1.64 1.34e-04 GO:0006974 response to DNA damage stimulus
1.56 2.21e-04 GO:0006396 RNA processing
1.83 2.33e-04 GO:0051329 interphase of mitotic cell cycle
1.82 2.35e-04 GO:0051325 interphase
1.21 2.48e-04 GO:0071840 cellular component organization or biogenesis
1.25 4.80e-04 GO:0071842 cellular component organization at cellular level
1.45 8.99e-04 GO:0006351 transcription, DNA-dependent
1.21 1.02e-03 GO:0060255 regulation of macromolecule metabolic process
1.21 1.11e-03 GO:0016043 cellular component organization
1.40 2.29e-03 GO:0007049 cell cycle
1.24 2.32e-03 GO:0010468 regulation of gene expression
1.66 2.35e-03 GO:0006397 mRNA processing
1.21 4.09e-03 GO:0019538 protein metabolic process
1.52 5.47e-03 GO:0000278 mitotic cell cycle
1.66 1.09e-02 GO:0006281 DNA repair
1.17 1.53e-02 GO:0019222 regulation of metabolic process
2.40 1.54e-02 GO:0018205 peptidyl-lysine modification
1.18 1.71e-02 GO:0031323 regulation of cellular metabolic process
1.94 2.09e-02 GO:0006730 one-carbon metabolic process
2.21 2.45e-02 GO:0040029 regulation of gene expression, epigenetic
1.38 2.63e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.23 2.79e-02 GO:0051252 regulation of RNA metabolic process
1.36 2.82e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.46 3.18e-02 GO:0051726 regulation of cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 3.10e-37 GO:0044424 intracellular part
1.17 1.56e-35 GO:0005622 intracellular
1.24 6.12e-35 GO:0043231 intracellular membrane-bounded organelle
1.24 7.32e-35 GO:0043227 membrane-bounded organelle
1.21 5.08e-32 GO:0043226 organelle
1.21 7.53e-32 GO:0043229 intracellular organelle
1.34 6.90e-29 GO:0005634 nucleus
1.51 3.02e-19 GO:0044428 nuclear part
1.46 1.14e-16 GO:0031974 membrane-enclosed lumen
1.46 2.61e-16 GO:0070013 intracellular organelle lumen
1.52 2.83e-16 GO:0031981 nuclear lumen
1.25 3.90e-16 GO:0044446 intracellular organelle part
1.44 2.62e-15 GO:0043233 organelle lumen
1.25 2.66e-15 GO:0044422 organelle part
1.53 1.30e-11 GO:0005654 nucleoplasm
1.15 1.85e-10 GO:0005737 cytoplasm
1.66 5.59e-09 GO:0044451 nucleoplasm part
1.05 9.65e-07 GO:0044464 cell part
1.05 1.02e-06 GO:0005623 cell
1.61 4.70e-05 GO:0005730 nucleolus
1.34 2.44e-04 GO:0005739 mitochondrion
1.85 5.17e-04 GO:0016604 nuclear body
1.13 7.78e-04 GO:0044444 cytoplasmic part
1.17 5.66e-03 GO:0032991 macromolecular complex
1.40 1.12e-02 GO:0031967 organelle envelope
1.37 2.75e-02 GO:0031975 envelope
1.17 2.79e-02 GO:0043234 protein complex
1.21 2.92e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 5.23e-12 GO:0005488 binding
1.17 4.60e-11 GO:0005515 protein binding
1.29 5.77e-10 GO:0003676 nucleic acid binding
1.29 4.33e-06 GO:0000166 nucleotide binding
1.17 5.99e-06 GO:0003824 catalytic activity
1.34 6.87e-06 GO:0016740 transferase activity
1.27 2.50e-05 GO:0003677 DNA binding
1.42 1.63e-03 GO:0003723 RNA binding
1.86 5.64e-03 GO:0003682 chromatin binding
1.27 8.24e-03 GO:0030554 adenyl nucleotide binding
1.28 8.34e-03 GO:0005524 ATP binding
1.27 1.03e-02 GO:0032559 adenyl ribonucleotide binding
1.40 1.27e-02 GO:0019899 enzyme binding
1.52 1.42e-02 GO:0019904 protein domain specific binding
1.15 1.56e-02 GO:0043167 ion binding
1.15 1.64e-02 GO:0046872 metal ion binding
1.15 1.79e-02 GO:0043169 cation binding
1.23 2.00e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.49 2.55e-02 GO:0016874 ligase activity
1.60 2.84e-02 GO:0016564 transcription repressor activity
1.23 2.94e-02 GO:0017076 purine nucleotide binding
1.23 3.27e-02 GO:0032553 ribonucleotide binding
1.23 3.27e-02 GO:0032555 purine ribonucleotide binding
1.79 4.98e-02 GO:0016741 transferase activity, transferring one-carbon groups