Motif ID: HLF.p2

Z-value: 1.043


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HLFchr17_+_533423200.096.4e-01Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_55866972 4.780 CES1
carboxylesterase 1
chr16_-_55867016 4.644 NM_001025194
NM_001025195
NM_001266
 CES1


carboxylesterase 1


chr8_-_6735438 2.338 NM_005218
 DEFB1
defensin, beta 1
chr2_-_113594325 2.302 NM_000576
 IL1B
interleukin 1, beta
chr2_-_216300770 2.181 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr2_+_113885137 2.170 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr12_-_91505215 2.155 LUM
lumican
chr13_-_20110884 2.006 NM_001141968
NM_130785
NM_199254
 TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr2_-_31637598 1.798 NM_000379
 XDH
xanthine dehydrogenase
chr2_+_113885145 1.611 IL1RN
interleukin 1 receptor antagonist
chr8_+_124194751 1.585 NM_032899
NM_207006
 FAM83A

family with sequence similarity 83, member A

chr8_+_124194873 1.555 FAM83A
family with sequence similarity 83, member A
chr11_+_69061599 1.521 NM_138768
 MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr19_-_41356193 1.496 NM_000762
 CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr12_-_52845862 1.403 NM_005555
 KRT6B
keratin 6B
chr20_+_16728997 1.343 NM_020157
 OTOR
otoraplin
chr20_-_56285576 1.268 NM_199169
NM_199170
 PMEPA1

prostate transmembrane protein, androgen induced 1

chr1_+_151032150 1.247 NM_006818
 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr9_+_105757592 1.211 NM_001340
 CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr5_-_147211141 1.194 SPINK1
serine peptidase inhibitor, Kazal type 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
18.99 1.75e-04 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
16.88 5.08e-04 GO:0048880 sensory system development
16.88 5.08e-04 GO:0048892 lateral line nerve development
16.88 5.08e-04 GO:0048895 lateral line nerve glial cell differentiation
16.88 5.08e-04 GO:0048925 lateral line system development
16.88 5.08e-04 GO:0048937 lateral line nerve glial cell development
16.88 5.08e-04 GO:0050935 iridophore differentiation
13.81 2.61e-03 GO:0060600 dichotomous subdivision of an epithelial terminal unit
12.66 5.05e-03 GO:0048846 axon extension involved in axon guidance
12.66 5.05e-03 GO:0090184 positive regulation of kidney development
11.82 1.28e-03 GO:0048485 sympathetic nervous system development
10.13 2.47e-02 GO:0030513 positive regulation of BMP signaling pathway
10.13 2.47e-02 GO:0048484 enteric nervous system development
7.24 1.57e-02 GO:0021545 cranial nerve development
6.33 1.43e-02 GO:0021675 nerve development
3.14 9.73e-06 GO:0006954 inflammatory response
1.99 1.74e-04 GO:0009611 response to wounding
1.95 1.69e-03 GO:0006952 defense response
1.82 4.25e-03 GO:0009605 response to external stimulus
1.42 4.80e-02 GO:0006950 response to stress

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.21 3.81e-07 GO:0005615 extracellular space
1.88 3.75e-05 GO:0044421 extracellular region part
1.54 2.84e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
4.95 2.78e-02 GO:0008009 chemokine activity