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• Activity deltas table
• Regulatory interactions
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Motif ID: HMX1.p2

Z-value: 1.184

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_51472816	6.292	NM_002774	KLK6	kallikrein-related peptidase 6
chr1_-_153433104	4.592	NM_002963	S100A7	S100 calcium binding protein A7
chr3_-_111314181	3.919	NM_024508	ZBED2	zinc finger, BED-type containing 2
chr11_+_69924407	3.039	NM_018043	ANO1	anoctamin 1, calcium activated chloride channel
chr22_-_37640287	2.792	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_+_4382882	2.727	NM_001759	CCND2	cyclin D2
chr22_-_37640187	2.690		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_-_107019001	2.613	NM_198057	TSC22D3	TSC22 domain family, member 3
chr17_+_74381186	2.551	NM_001142602	SPHK1	sphingosine kinase 1
chr2_-_192015733	2.513		STAT4	signal transducer and activator of transcription 4
chr17_+_74381419	2.427		SPHK1	sphingosine kinase 1
chr2_-_192015751	2.284		STAT4	signal transducer and activator of transcription 4
chrX_-_107018889	2.272		TSC22D3	TSC22 domain family, member 3
chr4_+_75310852	2.262	NM_001657	AREG	amphiregulin
chr2_-_192015934	2.197	NM_003151	STAT4	signal transducer and activator of transcription 4
chr2_-_192015706	2.151		STAT4	signal transducer and activator of transcription 4
chr10_-_135150368	2.058		CALY	calcyon neuron-specific vesicular protein
chr6_+_86159738	2.044		NT5E	5'-nucleotidase, ecto (CD73)
chrX_-_153599581	2.036		FLNA	filamin A, alpha
chr4_-_175443791	2.018	NM_000860 NM_001145816	HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)
chrX_-_153599719	2.011		FLNA	filamin A, alpha
chr4_-_175443601	1.941		HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_150521786	1.916	NM_019032 NM_025008	ADAMTSL4	ADAMTS-like 4
chr11_-_19262424	1.881	NM_024680	E2F8	E2F transcription factor 8
chrX_-_100914816	1.869	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr5_+_68485367	1.828	NM_022909	CENPH	centromere protein H
chr21_-_40685545	1.814		BRWD1	bromodomain and WD repeat domain containing 1
chr12_-_57634474	1.781	NM_020142	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr11_+_33061291	1.768		TCP11L1	t-complex 11 (mouse)-like 1
chrX_+_49028183	1.760	NM_002668	PLP2	proteolipid protein 2 (colonic epithelium-enriched)
chrX_-_132091223	1.731		HS6ST2	heparan sulfate 6-O-sulfotransferase 2
chr12_-_76425375	1.730	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr7_-_752742	1.727	NM_001164761	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_154946859	1.715	NM_001130041 NM_001202859 NM_003029	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr16_+_11439311	1.694		RMI2	RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr1_+_183155393	1.669		LAMC2	laminin, gamma 2
chr4_+_156680603	1.655		GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr8_+_31497267	1.641	NM_013962	NRG1	neuregulin 1
chr1_-_154946830	1.626		SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr16_+_11439279	1.626	NM_152308	RMI2	RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr14_+_90422260	1.618		TDP1	tyrosyl-DNA phosphodiesterase 1
chr7_+_130131921	1.614	NM_002402	MEST	mesoderm specific transcript homolog (mouse)
chr6_+_151186884	1.612		MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr19_+_676346	1.605	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr6_+_151186814	1.599	NM_001242767 NM_001242769 NM_015440	MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_+_30454396	1.590	NM_030915	LBH	limb bud and heart development homolog (mouse)
chr18_-_21166378	1.559		NPC1	Niemann-Pick disease, type C1
chr21_-_42879908	1.558	NM_001135099	TMPRSS2	transmembrane protease, serine 2
chr17_-_76183074	1.553	NM_003258	TK1	thymidine kinase 1, soluble
chrX_+_69509878	1.526	NM_012310	KIF4A	kinesin family member 4A
chr19_+_8429010	1.525	NM_001039667 NM_139314	ANGPTL4	angiopoietin-like 4
chr9_+_116263706	1.472	NM_130795	RGS3	regulator of G-protein signaling 3
chr7_+_143013218	1.414	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr19_+_2096930	1.411		IZUMO4	IZUMO family member 4
chr11_-_65667858	1.409		FOSL1	FOS-like antigen 1
chr4_-_10023094	1.402	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr17_-_80042414	1.392		FASN	fatty acid synthase
chr1_-_28503454	1.375	NM_000952 NM_001164723	PTAFR	platelet-activating factor receptor
chr16_+_88705000	1.360	NM_013278	IL17C	interleukin 17C
chr11_+_69455978	1.359		CCND1	cyclin D1
chr5_+_31193761	1.350	NM_004932	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)
chr1_-_154946801	1.347		SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr1_-_212588239	1.335	NM_001198862 NM_018252	TMEM206	transmembrane protein 206
chr1_-_212588073	1.314		TMEM206	transmembrane protein 206
chr9_+_33750463	1.307	NM_001197097 NM_007343 NM_001197098	PRSS3	protease, serine, 3
chr4_-_80993713	1.303		ANTXR2	anthrax toxin receptor 2
chr9_-_123639566	1.301	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr21_-_42880076	1.287		TMPRSS2	transmembrane protease, serine 2
chr11_-_128392061	1.287	NM_001162422 NM_005238	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_+_156863522	1.286	NM_001080471	PEAR1	platelet endothelial aggregation receptor 1
chr12_+_53440809	1.284	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr8_+_32405727	1.281	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr18_-_21166440	1.255	NM_000271	NPC1	Niemann-Pick disease, type C1
chr13_+_43148182	1.239	NM_003701	TNFSF11	tumor necrosis factor (ligand) superfamily, member 11
chr4_-_177713664	1.239	NM_005429	VEGFC	vascular endothelial growth factor C
chr10_-_99258365	1.228	NM_022362	MMS19	MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr5_-_140013034	1.212	NM_000591	CD14	CD14 molecule
chr11_-_65667860	1.207	NM_005438	FOSL1	FOS-like antigen 1
chr19_+_49055421	1.198	NM_177973	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1
chr21_-_44845920	1.189		SIK1	salt-inducible kinase 1
chr3_+_5021305	1.188		BHLHE40	basic helix-loop-helix family, member e40
chr17_+_73717596	1.184		ITGB4	integrin, beta 4
chr17_-_7166263	1.160	NM_001185023 NM_001307	CLDN7	claudin 7
chr11_+_69455938	1.160		CCND1	cyclin D1
chr17_+_73717556	1.157		ITGB4	integrin, beta 4
chr17_+_1959512	1.143	NM_001098202	HIC1	hypermethylated in cancer 1
chr1_-_149908721	1.118		MTMR11	myotubularin related protein 11
chr2_-_224903324	1.114	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr20_-_6103860	1.113		FERMT1	fermitin family member 1
chr19_-_52227220	1.112	NM_001523	HAS1	hyaluronan synthase 1
chr17_+_39968961	1.107	NM_021939	FKBP10	FK506 binding protein 10, 65 kDa
chr11_+_129245834	1.104	NM_003658	BARX2	BARX homeobox 2
chr5_-_140012730	1.099		CD14	CD14 molecule
chr1_-_26233367	1.097	NM_203399	STMN1	stathmin 1
chr2_-_216878314	1.092	NM_018000	MREG	melanoregulin
chr19_+_35782988	1.062	NM_001199216 NM_002361 NM_080600	MAG	myelin associated glycoprotein
chr1_+_6052699	1.059		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_-_26232890	1.056	NM_001145454 NM_005563	STMN1	stathmin 1
chr11_+_69455837	1.054	NM_053056	CCND1	cyclin D1
chr10_+_11865310	1.050	NM_153256	C10orf47	chromosome 10 open reading frame 47
chr10_-_101945686	1.038	NM_006459	ERLIN1	ER lipid raft associated 1
chr1_+_6052758	1.032		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr12_+_4430346	1.031	NM_020375	C12orf5	chromosome 12 open reading frame 5
chr22_-_36681757	1.028		MYH9	myosin, heavy chain 9, non-muscle
chr6_+_151187064	1.027		MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr16_-_90086299	1.026		DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr6_+_41606193	1.022	NM_005586	MDFI	MyoD family inhibitor
chr17_+_21279667	1.020	NM_021012	KCNJ12	potassium inwardly-rectifying channel, subfamily J, member 12
chr5_-_37371198	1.017		NUP155	nucleoporin 155kDa
chr12_-_76425207	1.016		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr1_-_27286875	1.011	NM_152365	C1orf172	chromosome 1 open reading frame 172
chr14_+_72398816	1.010	NM_001204423	RGS6	regulator of G-protein signaling 6
chrX_-_46618471	1.010	NM_032591	SLC9A7	solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr19_-_2096280	1.007		MOB3A	MOB kinase activator 3A
chr21_-_32931289	1.004	NM_003253	TIAM1	T-cell lymphoma invasion and metastasis 1
chr12_-_54778456	0.985	NM_015481	ZNF385A	zinc finger protein 385A
chr11_+_125495030	0.983	NM_001114121 NM_001114122 NM_001244846	CHEK1	checkpoint kinase 1
chr6_+_36644236	0.979	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_-_37371182	0.975	NM_153485	NUP155	nucleoporin 155kDa
chr11_-_65667809	0.968		FOSL1	FOS-like antigen 1
chr21_-_42880080	0.960	NM_005656	TMPRSS2	transmembrane protease, serine 2
chr19_-_2096263	0.956	NM_130807	MOB3A	MOB kinase activator 3A
chr3_+_5021096	0.952	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr1_-_6557448	0.951		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr8_-_29207795	0.940	NM_001394	DUSP4	dual specificity phosphatase 4
chr12_-_49259549	0.939	NM_014470	RND1	Rho family GTPase 1
chr6_-_40555111	0.939	NM_020737	LRFN2	leucine rich repeat and fibronectin type III domain containing 2
chr9_+_131644368	0.934	NM_001127245 NM_019594	LRRC8A	leucine rich repeat containing 8 family, member A
chrX_+_131157635	0.929	NM_001042452	MST4	serine/threonine protein kinase MST4
chr11_+_76494132	0.923	NM_015516	TSKU	tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr9_+_131644427	0.913		LRRC8A	leucine rich repeat containing 8 family, member A
chr17_+_73717515	0.910	NM_000213 NM_001005731	ITGB4	integrin, beta 4
chr6_+_33359624	0.908		KIFC1	kinesin family member C1
chr13_-_60738078	0.889	NM_001042517	DIAPH3	diaphanous homolog 3 (Drosophila)
chr3_+_5021141	0.889		BHLHE40	basic helix-loop-helix family, member e40
chr12_-_2986095	0.886		FOXM1	forkhead box M1
chr1_-_32169555	0.886		COL16A1	collagen, type XVI, alpha 1
chr4_+_41258941	0.883		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chrX_-_46618596	0.880		SLC9A7	solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr1_-_41328019	0.872		CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr9_+_131644780	0.867	NM_001127244	LRRC8A	leucine rich repeat containing 8 family, member A
chr1_-_197115566	0.866	NM_001206846 NM_018136	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr16_-_87350753	0.864		C16orf95	chromosome 16 open reading frame 95
chr2_-_101925051	0.858	NM_173647	RNF149	ring finger protein 149
chr11_+_63580922	0.853	NM_138471	C11orf84	chromosome 11 open reading frame 84
chr8_+_26371461	0.849	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr1_-_41328002	0.847	NM_133467	CITED4	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_-_149908759	0.841	NM_001145862	MTMR11	myotubularin related protein 11
chr11_+_63581031	0.840		C11orf84	chromosome 11 open reading frame 84
chr2_-_165478357	0.836	NM_004490	GRB14	growth factor receptor-bound protein 14
chr1_-_17338266	0.833	NM_001141973 NM_001141974 NM_022089	ATP13A2	ATPase type 13A2
chr19_-_46285746	0.828		DMPK	dystrophia myotonica-protein kinase
chr12_-_2986299	0.828	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr3_-_50336258	0.821	NM_001200018 NM_001200029	NAT6 HYAL3	N-acetyltransferase 6 (GCN5-related) hyaluronoglucosaminidase 3
chr14_+_65171149	0.820	NM_015549	PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_-_124310980	0.816	NM_012378	OR8B8	olfactory receptor, family 8, subfamily B, member 8
chr7_-_41742666	0.811	NM_002192	INHBA	inhibin, beta A
chr3_+_101546833	0.809	NM_001005474	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr5_+_87564729	0.808		LOC100505894	uncharacterized LOC100505894
chr17_-_7165788	0.803		CLDN7	claudin 7
chr20_-_6103562	0.800		FERMT1	fermitin family member 1
chr6_+_33359312	0.799	NM_002263	KIFC1	kinesin family member C1
chr1_+_155278538	0.799	NM_001135822 NM_001242824 NM_001242825 NM_002004	FDPS	farnesyl diphosphate synthase
chr2_-_102003923	0.797	NM_153836	CREG2	cellular repressor of E1A-stimulated genes 2
chr3_+_50192420	0.795		SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_752576	0.795	NM_001164762	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_32169619	0.793	NM_001856	COL16A1	collagen, type XVI, alpha 1
chr8_+_95653272	0.792		ESRP1	epithelial splicing regulatory protein 1
chr19_+_1026608	0.783		CNN2	calponin 2
chr17_+_1958354	0.781	NM_006497	HIC1	hypermethylated in cancer 1
chr11_+_66624875	0.781	NM_024036	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr6_+_36646489	0.781		CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_+_6052357	0.777	NM_001199861	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_+_35247838	0.772	NM_001005752	GJB3	gap junction protein, beta 3, 31kDa
chr12_-_58160823	0.767	NM_000785	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_+_163835668	0.766	NM_006775 NM_206853 NM_206854 NM_206855	QKI	QKI, KH domain containing, RNA binding
chr19_-_4535202	0.766	NM_001013706	PLIN5	perilipin 5
chr16_-_86542463	0.766		LOC400550	uncharacterized LOC400550
chr13_-_60737899	0.760		DIAPH3	diaphanous homolog 3 (Drosophila)
chr3_+_57994087	0.760	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr1_+_64058891	0.759	NM_002633	PGM1	phosphoglucomutase 1
chr16_+_23194037	0.758	NM_001039	SCNN1G	sodium channel, nonvoltage-gated 1, gamma
chr12_+_4647949	0.751	NM_001130862 NM_006479	RAD51AP1	RAD51 associated protein 1
chrX_+_131157231	0.743	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr11_-_28129701	0.740	NM_031217	KIF18A	kinesin family member 18A
chr17_-_9694613	0.738	NM_001105571 NM_001220493	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr19_-_42928152	0.738		LIPE	lipase, hormone-sensitive
chr19_+_58038744	0.737		ZNF549	zinc finger protein 549
chr19_-_47354060	0.736	NM_004069 NM_021575	AP2S1	adaptor-related protein complex 2, sigma 1 subunit
chr6_+_7727010	0.735	NM_001718	BMP6	bone morphogenetic protein 6
chr16_+_58497548	0.735	NM_020465	NDRG4	NDRG family member 4
chr1_+_155278727	0.733		FDPS	farnesyl diphosphate synthase
chr9_+_135854097	0.729	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr11_-_28129687	0.721		KIF18A	kinesin family member 18A
chr10_-_101380086	0.718		SLC25A28	solute carrier family 25, member 28
chr11_-_65640199	0.708	NM_016938	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr6_+_32121775	0.707	NM_001204103 NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 readthrough palmitoyl-protein thioesterase 2
chr1_-_6557471	0.705	NM_001042663	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_1026271	0.701	NM_004368 NM_201277	CNN2	calponin 2
chr1_+_155278677	0.700	NM_001135821	FDPS	farnesyl diphosphate synthase

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.59	4.70e-10	GO:0023051	regulation of signaling
1.20	1.33e-09	GO:0065007	biological regulation
1.13	1.88e-09	GO:0009987	cellular process
1.59	3.48e-08	GO:0009966	regulation of signal transduction
1.32	5.87e-08	GO:0023052	signaling
1.20	6.27e-08	GO:0050789	regulation of biological process
1.21	8.15e-08	GO:0050794	regulation of cellular process
1.48	1.44e-07	GO:0048583	regulation of response to stimulus
1.45	3.33e-07	GO:0030154	cell differentiation
1.36	8.71e-07	GO:0048731	system development
1.40	1.67e-06	GO:0048519	negative regulation of biological process
1.42	1.90e-06	GO:0048523	negative regulation of cellular process
1.33	2.58e-06	GO:0048856	anatomical structure development
1.42	3.57e-06	GO:0048869	cellular developmental process
1.41	5.84e-06	GO:0065008	regulation of biological quality
1.37	7.12e-06	GO:0048522	positive regulation of cellular process
1.30	9.63e-06	GO:0007165	signal transduction
1.30	9.67e-06	GO:0007275	multicellular organismal development
1.35	1.25e-05	GO:0048518	positive regulation of biological process
1.64	1.52e-05	GO:0050793	regulation of developmental process
1.28	1.82e-05	GO:0032502	developmental process
1.69	3.89e-05	GO:2000026	regulation of multicellular organismal development
1.81	5.75e-05	GO:0006928	cellular component movement
1.25	7.53e-05	GO:0051716	cellular response to stimulus
1.40	7.74e-05	GO:0048513	organ development
1.56	8.41e-05	GO:0010646	regulation of cell communication
2.27	1.58e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.20	2.68e-04	GO:0032501	multicellular organismal process
1.80	2.91e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.59	3.78e-04	GO:0009888	tissue development
1.26	4.00e-04	GO:0051179	localization
1.57	5.12e-04	GO:0022008	neurogenesis
1.59	5.40e-04	GO:0048699	generation of neurons
1.68	5.50e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.87	6.51e-04	GO:0016477	cell migration
1.26	7.60e-04	GO:0016043	cellular component organization
1.82	7.67e-04	GO:0048870	cell motility
1.82	7.67e-04	GO:0051674	localization of cell
1.43	7.76e-04	GO:0009653	anatomical structure morphogenesis
1.46	8.82e-04	GO:0051239	regulation of multicellular organismal process
1.31	9.01e-04	GO:0071842	cellular component organization at cellular level
1.43	9.54e-04	GO:0007399	nervous system development
1.26	1.02e-03	GO:0071840	cellular component organization or biogenesis
1.57	1.09e-03	GO:0040011	locomotion
1.81	1.34e-03	GO:0051094	positive regulation of developmental process
1.80	2.13e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.29	2.28e-03	GO:0071841	cellular component organization or biogenesis at cellular level
1.82	2.28e-03	GO:0007409	axonogenesis
1.63	2.37e-03	GO:0045595	regulation of cell differentiation
1.74	2.56e-03	GO:0000904	cell morphogenesis involved in differentiation
1.43	2.69e-03	GO:0035556	intracellular signal transduction
1.86	2.71e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.74	3.21e-03	GO:0031175	neuron projection development
1.45	3.75e-03	GO:0050790	regulation of catalytic activity
1.77	4.17e-03	GO:0048812	neuron projection morphogenesis
1.93	5.43e-03	GO:0022603	regulation of anatomical structure morphogenesis
1.16	5.72e-03	GO:0050896	response to stimulus
1.66	5.89e-03	GO:0050878	regulation of body fluid levels
1.39	7.01e-03	GO:0065009	regulation of molecular function
2.74	7.30e-03	GO:0051216	cartilage development
1.87	8.01e-03	GO:0009894	regulation of catabolic process
1.49	8.72e-03	GO:0032879	regulation of localization
1.21	9.79e-03	GO:0019222	regulation of metabolic process
2.84	9.94e-03	GO:0007160	cell-matrix adhesion
1.50	1.14e-02	GO:0048468	cell development
1.34	1.15e-02	GO:0007166	cell surface receptor linked signaling pathway
1.79	1.22e-02	GO:0007264	small GTPase mediated signal transduction
1.48	1.24e-02	GO:0009892	negative regulation of metabolic process
1.85	1.25e-02	GO:0007411	axon guidance
5.26	1.35e-02	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
1.42	1.36e-02	GO:0002376	immune system process
1.62	1.42e-02	GO:0042060	wound healing
1.57	1.79e-02	GO:0042325	regulation of phosphorylation
2.43	2.43e-02	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.58	2.86e-02	GO:0030030	cell projection organization
1.43	2.91e-02	GO:0051246	regulation of protein metabolic process
1.48	3.11e-02	GO:0031324	negative regulation of cellular metabolic process
1.55	3.55e-02	GO:0019220	regulation of phosphate metabolic process
1.55	3.55e-02	GO:0051174	regulation of phosphorus metabolic process
1.21	3.56e-02	GO:0031323	regulation of cellular metabolic process
1.50	3.69e-02	GO:0051128	regulation of cellular component organization
1.65	3.98e-02	GO:0001775	cell activation
1.94	4.06e-02	GO:0046578	regulation of Ras protein signal transduction
1.60	4.47e-02	GO:0048666	neuron development
3.26	4.54e-02	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.42	3.36e-07	GO:0005829	cytosol
1.38	3.25e-06	GO:0044459	plasma membrane part
1.22	3.06e-04	GO:0071944	cell periphery
1.21	7.27e-04	GO:0005886	plasma membrane
1.12	7.78e-04	GO:0005737	cytoplasm
1.69	1.67e-02	GO:0031012	extracellular matrix
3.79	2.95e-02	GO:0008305	integrin complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.23	3.18e-12	GO:0005515	protein binding
1.10	4.36e-07	GO:0005488	binding
1.56	6.39e-05	GO:0030234	enzyme regulator activity
2.87	4.91e-03	GO:0005089	Rho guanyl-nucleotide exchange factor activity
1.82	1.26e-02	GO:0005083	small GTPase regulator activity
2.52	1.90e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.62	2.40e-02	GO:0030695	GTPase regulator activity
1.60	3.27e-02	GO:0060589	nucleoside-triphosphatase regulator activity
2.07	3.29e-02	GO:0005085	guanyl-nucleotide exchange factor activity